Podřízení na něj spoléhají v časech dobrých i zlých. A když přijdou opravdové těžkosti, záleží často jen na jeho schopnostech, jak moc se podnik otřese, nebo zda padne úplně.

In the mountains of Topanga, OneRepublic bassist Brent Kutzle is asking $2.195 million for the scenic retreat he bought a year ago.

Nigerian percussionist Tony Allen was best known for his work with Afrobeat pioneer Fela Kuti's band Africa 70 and went on to play with Damon Albarn and Flea.

Jena : G. Fischer, 1890.

Jena : G. Fischer, 1887.

Berlin : A. Hirschwald, 1893.

Five persons were killed in a clash between two groups at Moti Hamirpar village in Kutch district of Gujarat on Saturday afternoon, police said.

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____________________________________________________________________________________________________________________________________________________________________________________________________ Ippassaq wifikkut attaveqaatitigut ajutoornerup kingorna arlallit...

The structures "nakute mo ii desu" and "hitsuyō wa arimasen" let people know they're not obliged to do something.

Congenital anomalies of the kidneys and urinary tracts (CAKUT) are disorders caused by defects in the development of the kidneys and their outflow tracts. The formation of the kidneys begins at week 3 and nephrogenesis continues until week 36, therefore, the kidneys and outflow tracts are susceptible to environmental risk factors that perturb development throughout gestation. Many genes have been implicated in kidney and outflow tract development, and mutations have been identified in patients with CAKUT. In severe cases of CAKUT, when the kidneys do not form, the fetus will not survive. However, in less severe cases, the baby can survive with combined kidney and outflow tract defects or they may only be identified in adulthood. In this review, we will cover the clinical presentation of CAKUT, its epidemiology, and its long-term outcomes. We will then discuss risk factors for CAKUT, including genetic and environmental contributions. Although severe CAKUT is rare, low nephron number is a much more common disorder with its effect on kidney function increasingly apparent as a person ages. Low nephron number appears to arise by the same mechanisms as CAKUT, but it differs in terms of the magnitude of the insult and the timing of when it occurs during gestation. By understanding the causes of CAKUT and low nephron number, we can begin to identify preventive treatments and establish clinical guidelines for how these patients should be followed.

TOM LEONARD: Last week, the Los Angeles trial of suspected serial killer Michael Gargiulo was treated to the bizarre sight of a moustachioed Ashton Kutcher - in a courtroom that wasn't a film set.

Scooter Braun's birthday brought out a bevy of stars to Los Angeles on Tuesday. And Justin Bieber, Ashton Kutcher and Mila Kunis led the cavalcade of luminaries.

Mila Kunis and Ashton Kutcher have poked fun at rumours of a split by sharing a lighthearted video.

The actor, 41, cut a casual figure in a basic white T-shirt and a pair of blue denim jeans, however the eye was drawn to Ashton's usual choice of headgear.

Scooter Braun got away from his feud with Taylor Swift to spend the 4th of July at a parade with his friend and client Justin Bieber, as well as Hailey Bieber, Ashton Kutcher and Mila Kunis.

They're a famous pair in the same profession

It was just another day for Mila Kunis on Tuesday in LA, but the starlet looked just as pretty as ever.

The actor was stoic during his Thursday outing with his wife. Earlier that day 'Hollywood Ripper' Michael Gargiulo was convicted of murdering Ashley Ellerin, 22, who was reportedly dating Kutcher.

Their outing comes a week to the day after Kunis celebrated her 36th birthday on August 14.

The 36-year-old actress carried an iced coffee to-go as she left the historic Nate 'n Al's Jewish deli before showing off an incredible impression of Bachelor in Paradise star John Paul Jones.

Ashton Kutcher twisted his toe 'in the other direction' as he was trying to put his and Mila Kunis' four-year-old daughter Wyatt to bed.

His ex-wife Demi Moore has opened up about their failed marriage - and the loss of their baby - in her soon to be released memoir.

Ashton Kutcher has fired back at his ex-wife Demi Moore following her shock claims about their relationship in her bombshell memoir.

Demi Moore has criticised ex-husband Ashton Kutcher for 'shaming' her by sharing a picture of her in her underwear during their marriage in the latest bombshell revelation from her tell-all memoir.

'Yeah, I'll say fired, sure,' the 41-year-old said in an interview with FirstWeFeast.com . 'At a certain point we just kind of agreed that it wasn't working out. More him than me.'

Ashton Kutcher used a text number that he tweeted out amid the fallout from ex-wife Demi Moore's memoir to call for Donald Trump to be impeached over the Ukraine scandal.

The couple was coming off a trying week following the release of Moore's memoir, which included many tidbits about The Ranch actor.

The celebrity couple met up with Mila's dad Mark Kunis and a group of other family and their friends at the wildly popular Nate 'N Al's Delicatessen in Beverly Hills on a sunny Saturday.

The 36-year-old actress told comedian Andrea Savage that she's a huge fan of reality television and even had a notion to throw her hat into the realm.

The 41-year-old Two And A Half Men star was spotted out with his children on a shopping trip on Tuesday. Mom Mila Kunis, 36, didn't appear to be with her family for the jaunt/,

They met on the popular 90s sitcom, That 70s Show. And on Sunday, Mila Kunis, 36, and Ahston Kutcher, 41, stepped out with their two children to head to the Yellow Balloon to get the kids haircuts.

Mila Kunis and Ashton Kutcher and their two children look like the quintessential family as they enjoy a day out in Los Angeles. Ashton's show The Ranch finally gets series finale release date.

They are known to twin on family outings. And Ashton Kutcher and Mila Kunis were back at it again on Monday. The couple took their daughter Wyatt, aged five, and son Dimitri, aged three, out to dance class.

They are parents of two children under five. And on Thursday, Mila Kunis, 36, and Ashton Kutcher, 41, enjoyed a kid-free date night in West Hollywood.

Ashton sported a grey T-shirt emblazoned with the message 'support your local farmers'

Ashton Kutcher and Mila Kunis announced on Sunday morning that they had created their own Quarantine Wine where 100% of proceeds would be given to charity.

Ashton Kutcher and Mila Kunis shared a new snap of the couple kissing, as they get ready for their at-home interview with The Tonight Show Starring Jimmy Fallon.

Ashton Kutcher and Mila Kunis opened up about the Quarantine Wine brand they launched last month, which has far surpassed their expectations.

The Two and a Half Men actor, 42, and the Bad Moms star, 36, took part in a game of voice swap where they had to speak while the other person mimed.

The A-listers attended the party at the Saddle Ranch restaurant in Los Angeles for the event thrown by the well-known record executive on Tuesday.

Sunshine Coast cabinet maker Zac Whiting, 18, has been locked up at Kuta Police station since Friday morning after he was accused of punching guard Adni Junus Liu.

He sparked an infamous twitter war in 2014 against Ashton Kutcher. But now Charlie Sheen has said he blames his ego for his temper tirades and regrets the way he treated the actor stepping into his role.

Ashton Kutcher braved the open air to pick-up some well deserved takeout for his family at Black Market Liquor Bar in Studio City. Kutcher sported an N95 face mask and black disposable gloves.

Five persons were killed in a clash between two groups at Moti Hamirpar village in Kutch district of Gujarat on Saturday afternoon, police said. A group of people wielding sharp weapons attacked another group on suspicion that they were informing police about the hooch trade in nearby areas, said an official. Liquor production and sale are prohibited in Gujarat. Four persons were killed on the spot while another died at a hospital at Rapar. Kutch-East Superintendent of Police Parikshita Rathod said teams from nearby police stations and the local crime branch was deployed in the village to maintain peace. The deceased were identified as Jesang Rajput, Amra Rajput, Petha Bhavan Rajput, Vela Pecha and and Akhabhai. Further probe was on, the SP said.

Prior to 1995, KSRTC did not have a single bus on this route, but nowadays there are 24 trips between Manathavady in Wayanad and Kutta in Kodagu, Karnataka. By the second stop on the journey, there is not a seat vacant. P Sainath continues his series on the agrarian crisis in Wayanad.

Hockey India condoled the demise of Pandanda Kuttappa, a legendary figure in the region of Coorg who gave the sport the world famous Kuttani, family hockey tournament.

Nayanthara, the lady superstar is all set to play a goddess for the first time in her career in the upcoming movie Mookuthi Amman. The movie, which is touted to be a satirical comedy, is currently under the post-production stage. Recently,

Kutch Lignite Thermal Power Station