computational

Computational Software: A New Paradigm for EDA Tools

Cadence has a new white paper out on Computational Software . I've written on these topics in Breakfast Bytes, most recently in the posts: Computational Software System Analysis: Computational...

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computational

New computational method unravels single-cell data from multiple people

A new computational method for assigning the donor in single cell RNA sequencing experiments provides an accurate way to unravel data from a mixture of people. The Souporcell method could help study how genetic variants in different people affect which genes are expressed during infection or response to drugs, and help research into transplants, personalized medicine and malaria.




computational

GSK hires computational drug design expert Dr Kim Branson as new head of machine learning and AI

British multinational GlaxoSmithKline have hired computational drug design expert Dr Kim Branson as the company’s new Senior Vice President, Global Head of Artificial Intelligence and Machine Learning.

In his new role, the biotech veteran will oversee projects which use AI to identify novel targets for potential medicines.

Dr Branson brings to the role more than 15 years’ worth of experience in biotech and academia having held positions at a number of Silicon Valley firms including Gliimpse, Lumia and Hessian Informatics.

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computational

Toward a Containment Strategy for Smallpox Bioterror: An Individual-Based Computational Approach

Abstract

An individual-based computational model of smallpox epidemics in a two-town county is presented and used to develop strategies for bioterror containment. A powerful and feasible combination of preemptive and reactive vaccination and isolation strategies is developed which achieves epidemic quenching while minimizing risks of adverse side effects. Calibration of the model to historical data is described. Various model extensions and applications to other public health problems are noted.

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computational

Toward a Containment Strategy for Smallpox Bioterror : An Individual-Based Computational Approach


Brookings Institution Press 2004 55pp.

In the United States, routine smallpox vaccination ended in 1972. The level of immunity remaining in the U.S. population is uncertain, but is generally assumed to be quite low. Smallpox is a deadly and infectious pathogen with a fatality rate of 30 percent. If smallpox were successfully deployed as an agent of bioterrorism today, the public health and economic consequences could be devastating.

Toward a Containment Strategy for Smallpox Bioterror describes the scientific results and policy implications of a simulation of a smallpox epidemic in a two-town county. The model was developed by an interdisicplinary team from the Johns Hopkins Bloomberg School of Public Health and the Brookings Institution Center on Social and Economic Dynamics, employing agent-based and other advanced computational techniques. Such models are playing a critical role in the crafting of a national strategy for the containment of smallpox by providing public health policymakers with a variety of novel and feasible approaches to vaccination and isolation under different circumstances. The extension of these techniques to the containment of emerging pathogens, such as SARS, is discussed.

About the Authors:
Joshua M. Epstein and Shubha Chakravarty are with the Brookings Institution. Derek A. T. Cummings, Ramesh M. Singha, and Donald S. Burke are with the Johns Hopkins Bloomberg School of Public Health.

ABOUT THE AUTHORS

Derek Cummings
Donald S. Burke
Joshua M. Epstein
Ramesh M. Singa
Shubha Chakravarty

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Ordering Information:
  • {9ABF977A-E4A6-41C8-B030-0FD655E07DBF}, 978-0-8157-2455-1, $19.95 Add to Cart
      
 
 




computational

Coupled Contagion Dynamics of Fear and Disease: Mathematical and Computational Explorations

Published version of the CSED October 2007 Working Paper

ABSTRACT

Background

In classical mathematical epidemiology, individuals do not adapt their contact behavior during epidemics. They do not endogenously engage, for example, in social distancing based on fear. Yet, adaptive behavior is well-documented in true epidemics. We explore the effect of including such behavior in models of epidemic dynamics.

Methodology/Principal Findings

Using both nonlinear dynamical systems and agent-based computation, we model two interacting contagion processes: one of disease and one of fear of the disease. Individuals can “contract” fear through contact with individuals who are infected with the disease (the sick), infected with fear only (the scared), and infected with both fear and disease (the sick and scared). Scared individuals–whether sick or not–may remove themselves from circulation with some probability, which affects the contact dynamic, and thus the disease epidemic proper. If we allow individuals to recover from fear and return to circulation, the coupled dynamics become quite rich, and can include multiple waves of infection. We also study flight as a behavioral response.

Conclusions/Significance

In a spatially extended setting, even relatively small levels of fear-inspired flight can have a dramatic impact on spatio-temporal epidemic dynamics. Self-isolation and spatial flight are only two of many possible actions that fear-infected individuals may take. Our main point is that behavioral adaptation of some sort must be considered.”

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Publication: PLoS One Journal
      
 
 




computational

Development of a computational modeling laboratory for examining tobacco control policies: Tobacco Town

       




computational

Development of a computational modeling laboratory for examining tobacco control policies: Tobacco Town

       




computational

A dedicated home for computational science

Originally posted on - blogs by NPG staff

This guest blog comes from Fernando Chirigati, Chief Editor of Nature Computational Science.  Read more




computational

Digging up facts about fake news: The Computational Propaganda Project

This may come as a surprise to most serious policymakers, but here’s a fact: not all that is “news” is fact-checked information. Worse, non-facts are frequently introduced into stories and passed off as facts. Welcome to the new information world. It is unsettling, and hardly augurs well for robust policymaking. So what can be done about it?




computational

Computational neuroscience : Second Latin American Workshop, LAWCN 2019, São João Del-Rei, Brazil, September 18-20, 2019, proceedings [Electronic book] / Vinícius Rosa Cota, Dante Augusto Couto Barone, Diego Roberto Colombo Dias, Laila Cris

Cham, Switzerland : Springer, [2019]




computational

Applied computational fluid dynamics and turbulence modeling [Electronic book] : practical tools, tips and techniques / Sal Rodriguez.

Cham : Springer, c2019.




computational

Applications of computational intelligence [Electronic book] : Second IEEE Colombian Conference, ColCACI 2019, Barranquilla, Colombia, June 5-7, 2019, Revised Selected Papers / Alvaro David Orjuela-Cañón, Juan Carlos Figueroa-García, Juli&#

Cham : Springer, 2020.




computational

Computational gas-solids flows and reacting systems: theory, methods and practice / [edited by] Sreekanth Pannala, Madhava Syamlal, Thomas J. O'Brien

Barker Library - TA357.5.M84 C646 2011




computational

Advanced computational dynamics of particles, materials and structures / Jason Har and Kumar K. Tamma

Barker Library - TA352.H365 2012




computational

Computational fluid-structure interaction: methods and applications / Yuri Bazilevs, Department of Structural Engineering, University of California, San Diego, USA, Kenji Takizawa, Department of Modern Mechanical Engineering and Waseda Institute for Advan

Barker Library - TA357.5.F58 B39 2013




computational

Computational methods in multiphase flow VII / editors, C.A. Brebbia, P. Vorobieff

Barker Library - TA357.5.M84 I585 2013




computational

Using HPC for computational fluid dynamics: a guide to high performance computing for CFD engineers / Shamoon Jamshed

Barker Library - TA357.J384 2015




computational

Industrial computational fluid dynamics: September 21-25, 2015 / lecture series directors, J.-M. Buchlin & Ph. Planquart

Barker Library - TA357.5.M43 I548 2015




computational

38th advanced computational fluid dynamics: adjoint methods and their application in computational fluid dynamics: September 14-17, 2015 / edited by H. Deconinck & T. Horvath

Barker Library - TA357.5.D37 A15 2015




computational

Finite element methods for computational fluid dynamics: a practical guide / Dmitri Kuzmin, TU Dortmund University, Dortmund, Germany, Jari Hämäläinen, Lappeenranta University of Technology, Lappeenranta, Finland

Barker Library - TA357.5.D37 K89 2015




computational

Advanced computational fluid and aerodynamics / Paul G Tucker

Barker Library - TA357.5.D37 T83 2016




computational

A first course in computational fluid dynamics / H. Aref, Virginia Polytechnic Institute and State University, S. Balachandar, University of Florida

Barker Library - TA357.5.D37 A74 2018




computational

Industrial computational fluid dynamics / edited, J.-M. Buchlin & Ph. Planquart

Barker Library - TA357.5.D37 I53 2017




computational

Computational methods and clinical applications for spine imaging: 6th International Workshop and Challenge, CSI 2019, Shenzhen, China, October 17, 2019, proceedings / Yunliang Cai, Liansheng Wang, Michel Audette, Guoyan Zheng, Shuo Li (eds.)

Online Resource




computational

The Oxford handbook of computational economics and finance / edited by Shu-Heng Chen, Mak Kaboudan, and Ye-Rong Du

Dewey Library - HB143.5.O94 2016




computational

Computational systems toxicology / edited by Julia Hoeng and Manuel C. Peitsch




computational

Introduction to computational linear algebra / Nabil Nassif, American University of Beirut, Lebanon, Jocelyne Erhel, INRIA, Rennes, France, Bernard Philippe, INRIA, Rennes, France

Nassif, Nabil




computational

Research in computational molecular biology: 20th Annual Conference, RECOMB 2016, Santa Monica, CA, USA, April 17-21, 2016, Proceedings / Mona Singh (ed.)

Online Resource




computational

Application of computational intelligence to biology / Ravi Bhramaramba, Akula Chandra Sekhar, editors

Online Resource




computational

Algorithms for computational biology: third International Conference, AlCoB 2016, Trujillo, Spain, June 21-22, 2016, Proceedings / María Botón-Fernández, Carlos Martín-Vide, Sergio Santander-Jiménez, Miguel A. Vega-Rodríguez

Online Resource




computational

Computational intelligence methods for bioinformatics and biostatistics: 12th International Meeting, CIBB 2015, Naples, Italy, September 10-12, 2015, revised selected papers / Claudia Angelini, Paola MV Rancoita, Stefano Rovetta (eds.)

Online Resource




computational

Computational methods in systems biology: 14th International Conference, CMSB 2016, Cambridge, UK, September 21-23, 2016, Proceedings / edited by Ezio Bartocci, Pietro Lio, Nicola Paoletti

Online Resource




computational

Computational biology and bioinformatics: gene regulation: gene, RNA, protein, epigenetics / editor, Ka-Chun Wong, Department of Computer Science, City University of Hong Kong, Kowloon Tong, Hong Kong

Hayden Library - QH324.2.W66 2016




computational

Algorithms for computational biology: 4th International Conference, AlCoB 2017, Aveiro, Portugal, June 5-6, 2017, Proceedings / edited by Daniel Figueiredo, Carlos Martín-Vide, Diogo Pratas, Miguel A. Vega-Rodríguez (eds.)

Online Resource




computational

11th International Conference on Practical Applications of Computational Biology & Bioinformatics / Florentino Fdez-Riverola, Mohd Saberi Mohamad, Miguel P. Rocha, Juan F. De Paz, Tiago Pinto, editors

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computational

Computational methods in systems biology: 15th International Conference, CMSB 2017, Darmstadt, Germany, September 27-29, 2017, Proceedings / Jérôme Feret, Heinz Koeppl (eds.)

Online Resource




computational

Advanced computational methods in life system modeling and simulation: International Conference on Life System Modeling and Simulation, LSMS 2017 and International Conference on Intelligent Computing for Sustainable Energy and Environment, ICSEE 2017, Nan

Online Resource




computational

Stochastic processes, multiscale modeling, and numerical methods for computational cellular biology David Holcman, editor

Online Resource




computational

Computational intelligence methods for bioinformatics and biostatistics: 13th International Meeting, CIBB 2016, Stirling, UK, September 1-3, 2016, Revised selected papers / Andrea Bracciali, Giulio Caravagna, David Gilbert, Roberto Tagliaferri (eds.)

Online Resource




computational

Computational systems biology: methods and protocols / edited by Tao Huang

Online Resource




computational

Research in Computational Molecular Biology: 22nd Annual International Conference, RECOMB 2018, Paris, France, April 21-24, 2018, Proceedings / edited by Benjamin J. Raphael

Online Resource




computational

Algorithms for computational biology: 5th International Conference, AlCoB 2018, Hong Kong, China, June 25-26, 2018, Proceedings / Jesper Jansson, Carlos Martín-Vide, Miguel A. Vega-Rodríguez (eds.)

Online Resource




computational

Computational methods in systems biology: 16th International Conference, CMSB 2018, Brno, Czech Republic, September 12-14, 2018, Proceedings / Milan Češka, David Šafránek (eds.)

Online Resource




computational

Advances in bioinformatics and computational biology: 11th Brazilian Symposium on Bioinformatics, BSB 2018, Niterói, Brazil, October 30-November 1, 2018, Proceedings / Ronnie Alves (ed.)

Online Resource




computational

Computational biology: a hypertextbook / Scott T. Kelley, Department of Biology, San Diego State University, San Diego, California, and Dennis Didulo, Becton, Dickinson and Company, San Diego, California

Online Resource




computational

Computational intelligence methods for bioinformatics and biostatistics: 14th International Meeting, CIBB 2017, Cagliari, Italy, September 7-9, 2017, revised selected papers / Massimo Bartoletti [and 6 more] (eds.)

Online Resource




computational

Research in computational molecular biology: 23rd Annual International Conference, RECOMB 2019, Washington, DC, USA, May 5-8, 2019, Proceedings / Lenore J. Cowen (eds.)

Online Resource




computational

Algorithms for computational biology: 6th International Conference, AlCoB 2019, Berkeley, CA, USA, May 28-30, 2019, Proceedings / Ian Holmes, Carlos Martín-Vide, Miguel A. Vega-Rodríguez, editors

Online Resource




computational

Advances in Computational Intelligence: 15th International Work-Conference on Artificial Neural Networks, IWANN 2019, Gran Canaria, Spain, June 12-14, 2019, Proceedings, Part I / edited by Ignacio Rojas, Gonzalo Joya, Andreu Catala

Online Resource