Governor Nyesom Wike of Rivers State, on Friday arrested 14 persons hidden in two trailers conveying cattle from Adamawa State to Port Harcourt, the State’s capital. Wike told reporters that the trailers were intercepted following a tip-off from well-meaning Nigerians, who told the State authorities that some Northerners were making their way into Port Harcourt. […]

COVID-19 lockdown: Rivers Govt arrests 14 persons, to auction 2 truckload of cows

A frontline activist, Ebun-Olu Adegboruwa, SAN, has accused the Governor of Rivers State, Nyesom Wike of turning into a dictator. He listed some attributes of dictatorship being displayed by the Governor to include the arbitrary arrest of pilots and oil workers; the closure of State boundaries and now an executive order to auction all vehicles […]

COVID-19 lockdown: Gov. Wike becoming a dictator in Rivers – Senior lawyer, Adegboruwa

Governor Nyesom Wike of Rivers State has told the people of the State and the entire Nigerians to hold the President Muhammadu Buhari-led Federal Government responsible if COVID-19 escalates in the State. Wike said this in his statewide broadcast on Friday, adding that nobody should be surprised if the coronavirus cases in the State rise […]

COVID-19: Hold Buhari govt responsible if coronavirus escalates in Rivers – Wike cries out

It is not for nothing that it is said that two heads are better than one. Then Prof. Kimse Okoko modified it to ‘two good heads.’ I believe that Gov. Nyesom Wike should involve his entire cabinet members (as it appears he does not) in managing Covid-19 in Rivers State. If he does that, I […]

Senibo Chris Finebone: Way to go in fighting COVID-19 in Rivers State(1)

BY EMEKA EJERE Governor Nyesom Wike, of Rivers State has accused the state’s deputy commissioner of police, DCP Adamu Abubakar of sabotaging the lockdown in the state by issuing illegal letters to companies after collecting money from them. Wike, who spoke in an interview on Thursday, said the deputy commissioner of Police released people he […]

The post Police collecting bribe, sabotaging lockdown in Rivers – Wike appeared first on Hallmarknews.

A man has been taken to hospital after a he was hurt by a bull in Southland this afternoon.St John Ambulance tweeted that they had been called to Riversdale, 30 kilometres north-west of Gore, just after 4pm."Two vehicles attended...

A horror crash involving a truck and a tanker carrying a flammable substance has led to the closure of the N2, near the Mtunzini Toll Plaza on the KwaZulu-Natal north coast. ......

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(MENAFN - Jordan News Agency) Irbid, May 9 (Petra) �� The number of coronavirus patients in the isolation ward at the King Abdullah University Hospita... ......

TROOP D NEWS RELEASE May 9, 2020 **UPDATE** Driver and Passenger Killed in Head-On Crash in Calcasieu Parish Sulphur, LA. - The deceased passenger is identified as 38-year-old Michael C. Vidrine of Eunice, LA. Original Release - On May 8, 2020, at approximately 4:15 p.m., Troopers from Louisiana State Police Troop D responded to a two-vehicle, fatal crash on LA Hwy 27 on top of...

The standoff has created massive traffic jams at border control gates of member countries.

Prague Daily Monitor

According to a story run in Deník N, a blind woman going out for a morning walk ran into a nightmare scenario on Monday in Prague's trendy Žižkov area.

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Prague Daily Monitor

As seems to be the norm this winter, the Czech Republic had another day of record warm temperatures on Sunday. With the warm temperatures came high velocity winds which knocked out electricity for hundreds of homes in the western part of the country, caused traffic accidents and as much as a 30% halt in railways service.

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ADB today approved a $200 million loan to pilot an integrated approach to river restoration in one of the tributaries of the Yangtze River Basin in the PRC. The project in...

ADB has approved a $100 million loan for a demonstration project that will help clean up the Xin’an River in Anhui Province in the PRC. The project will also pilot an innovative financing mechanism to reduce rural pollution...

SST26VF040A Software Driver

SST26VF020A Software Driver

AN3444 Driving LEDs with Constant Current and Sequential Linear LED Drivers

At HARMAN, our Connected Car division designs, engineers and innovates every day to provide connected solutions for our most valued partners, and our compute model integration with Mercedes-Benz is no exception. Earlier this year, the luxury vehicle ...

IFA 2015, BERLIN – HARMAN International Industries, Incorporated (NYSE:HAR), the premier connected technologies company for automotive, consumer and enterprise markets, today announced the world’s first aftermarket amplifiers to feature HARMAN’s Clari-Fi...

Some of the first dinosaurs may have lived and hunted on the largest delta plain ever discovered, which was 10 times the size of the Amazon river delta

We’ve found a 200-metre cliff in Mars's Hellas basin, the first evidence of a river that flowed on the planet for more than 100,000 years

Title: Taking Away Car Keys Can Be Tough for Older Drivers
Category: Health News
Created: 4/27/2012 6:06:00 PM
Last Editorial Review: 4/30/2012 12:00:00 AM

Title: Upper-Body Strength Key for NASCAR Drivers
Category: Health News
Created: 4/27/2012 6:06:00 PM
Last Editorial Review: 4/30/2012 12:00:00 AM

Title: Pot-Booze Combo More Dangerous for Teen Drivers Than Alcohol Alone
Category: Health News
Created: 4/28/2014 9:35:00 AM
Last Editorial Review: 4/28/2014 12:00:00 AM

Title: Health Tip: Be a Safe Driver for Your Kids
Category: Health News
Created: 5/5/2017 12:00:00 AM
Last Editorial Review: 5/5/2017 12:00:00 AM

Title: Women Are Much Safer Drivers Than Men, British Study Finds
Category: Health News
Created: 4/7/2020 12:00:00 AM
Last Editorial Review: 4/7/2020 12:00:00 AM

ABSTRACT

Host persistence of bacteria is facilitated by mutational and recombinatorial processes that counteract loss of genetic variation during transmission and selection from evolving host responses. Genetic variation was investigated during persistent asymptomatic carriage of Neisseria meningitidis. Interrogation of whole-genome sequences for paired isolates from 25 carriers showed that de novo mutations were infrequent, while horizontal gene transfer occurred in 16% of carriers. Examination of multiple isolates per time point enabled separation of sporadic and transient allelic variation from directional variation. A comprehensive comparative analysis of directional allelic variation with hypermutation of simple sequence repeats and hyperrecombination of class 1 type IV pilus genes detected an average of seven events per carrier and 2:1 bias for changes due to localized hypermutation. Directional genetic variation was focused on the outer membrane with 69% of events occurring in genes encoding enzymatic modifiers of surface structures or outer membrane proteins. Multiple carriers exhibited directional and opposed switching of allelic variants of the surface-located Opa proteins that enables continuous expression of these adhesins alongside antigenic variation. A trend for switching from PilC1 to PilC2 expression was detected, indicating selection for specific alterations in the activities of the type IV pilus, whereas phase variation of restriction modification (RM) systems, as well as associated phasevarions, was infrequent. We conclude that asymptomatic meningococcal carriage on mucosal surfaces is facilitated by frequent localized hypermutation and horizontal gene transfer affecting genes encoding surface modifiers such that optimization of adhesive functions occurs alongside escape of immune responses by antigenic variation.

IMPORTANCE Many bacterial pathogens coexist with host organisms, rarely causing disease while adapting to host responses. Neisseria meningitidis, a major cause of meningitis and septicemia, is a frequent persistent colonizer of asymptomatic teenagers/young adults. To assess how genetic variation contributes to host persistence, whole-genome sequencing and hypermutable sequence analyses were performed on multiple isolates obtained from students naturally colonized with meningococci. High frequencies of gene transfer were observed, occurring in 16% of carriers and affecting 51% of all nonhypermutable variable genes. Comparative analyses showed that hypermutable sequences were the major mechanism of variation, causing 2-fold more changes in gene function than other mechanisms. Genetic variation was focused on genes affecting the outer membrane, with directional changes in proteins responsible for bacterial adhesion to host surfaces. This comprehensive examination of genetic plasticity in individual hosts provides a significant new platform for rationale design of approaches to prevent the spread of this pathogen.

Drivers with blood-alcohol levels below legal limits cause 15% of all crash deaths that involve alcohol, a study in the March issue of the American Journal of Preventive Medicine finds.

Key Points

Professional drivers show a higher prevalence of obstructive sleep apnoea (OSA) compared with the general population. Furthermore, there is concern about the association between OSA and car crash risk given that drivers with OSA show an increased risk for car accidents. Despite this risk, OSA is often underdiagnosed and undertreated in this population, mainly due to lack of appropriate screening and sleep study referrals. Polysomnography (PSG), the gold standard test, is inappropriate for systematic screening because of its high expense, complexity and relative inaccessibility in this population. Therefore, there is a strong demand for good screening tools, including both subjective and objective data that may assist in early identification of possible OSA among professional drivers and, thus, aid in PSG examination referral and OSA management in an accredited sleep centre. However, there is considerable disagreement over screening methods and criteria for triggering a sleep study referral in different countries. There is also a strong need for further research in the area of OSA screening of commercial drivers in order to improve the diagnostic accuracy of screening tools and ensure that patients with OSA are accurately identified.

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