The invention relates to the use of NF-κB inducing kinase (NIK) and related molecules for the modulation of signal activities controlled by cytokines, and some new such molecules.

The invention relates to indolesulfonyl halogenides which are useful for the protection of organic compounds comprising at least one guanidino moiety and/or at least one amino group. The invention further relates to a process for their preparation and their use as protecting reagents. The invention also relates to the process for the protecting reaction and to the protected compounds thereof.

Disclosed herein are polypeptides, polynucleotides encoding, cells and organisms comprising novel DNA-binding domains, including TALE DNA-binding domains. Also disclosed are methods of using these novel DNA-binding domains for modulation of gene expression and/or genomic editing of endogenous cellular sequences.

IL4/IL13-binding proteins comprise binding domains, which inhibit IL4/IL13 binding to IL4Ralpaha and common gamma chain complexes (Type 1) and inhibit IL4 binding to IL4Ralpha and IL13Ralpha1 complexes (Type 2), and IL13 binding to IL13Ralpha1 and/or IL13Ralpha2, are useful in the treatment of cancer, inflammatory, and other pathological conditions, such as allergic or fibrotic conditions, especially pulmonary conditions.

The present invention relates to treating a tissue in a mammal from the effects of reperfusion using flagellin.

A spindle structure for an optical disc and an optical disc drive employing the spindle structure are provided. The spindle structure includes a spindle motor having a rotation axis, a spindle that is coupled to the rotation axis, and a sliding cone coupled to the spindle and inserted into a center hole of the optical disc. The sliding cone includes a plurality of hook-shaped guide rods extended toward the spindle, and the spindle includes guide holes, to which the plurality of hook-shaped guide rods are inserted into and coupled.

A turn table for a spindle motor and a spindle motor having the turn table are provided, the turn table for a spindle motor according to an exemplary embodiment comprising a clamping plate configured to have a locking protrusion protruding from an inner surface of a first recess thereof, the first recess being concavely formed in an outer circumference of the clamping plate; and a turn-table body configured to have a second recess to receive the clamping plate, and a plurality of protrusions protruding from an inner surface defined by the second recess towards the first recess to lock the locking protrusion.

A turn table of a spindle motor is provided, wherein an outer diameter of a vertical portion at the disk insertion unit facing an inner periphery of a small-diameter disk is smaller by 0.01% to 0.15% than the inner periphery of the small-diameter disk to enable a chucking of the small-diameter disk having an inner diameter of an inner periphery smaller than 15 mm.

A cob conveying and cleaning system for use with a corn harvester, incorporating air induction in cooperation with an air flow from the harvester, for cleaning and separating lighter crop residue to be returned to the field from a mixed flow of the residue and cobs, such that the cleaned cobs can be collected, and the lighter residue optionally spread on the field. The air flow and induction are combined to cooperatively lift or draw the lighter residue from the mixed flow, and to optionally spread the removed lighter residue over a field. The induction apparatus can be located on the harvester, and used as a residue spreader when cobs are not collected.

A spreader assembly for a combine harvester, the assembly including a pair of disks configured to be rotated such that chaff material dropped onto the disks is spread about the combine harvester, wherein each disk is operably connected to its own motor and a spreader frame assembly. The spreader frame assembly includes a first side support pivotably connected to a frame of the combine harvester, a second side support pivotably connected to the frame of the combine harvester, and at least one disk support configured to support at least one of the pair of disks. The spreader frame assembly further defines an opening configured such that when the combine harvester is windrowing material, no portion of the spreader frame assembly interferes with the flow of windrowing material.

A windrow door assembly for controlling a direction of flow of crop residue expelled from a combine is disclosed. The window door assembly may generally include a door panel extending between a first end and a second end. The door panel may be moveable between a closed position, wherein the crop residue being expelled from the combine is directed along the door panel into a spreader of the combine, and an opened position, wherein the crop residue is directed along the door panel towards a rear opening of the combine. In addition, the windrow door assembly may include a deflector panel rotatably coupled to the door panel. The deflector panel may be configured to alter the direction of flow of the crop residue when the door panel is in the opened position.

Provided is a method for shutting down an indirect internal reforming SOFC, in which a hydrocarbon-based fuel is reliably reformed, and the oxidative degradation of the anode can be prevented by a reformed gas. A method for shutting down an indirect internal reforming SOFC including a reformer; an SOFC; a combustion region for combusting the anode off-gas of the SOFC; and an enclosure for housing the reformer, the SOFC, and the combustion region, wherein the method includes causing the flow rate of a fuel supplied to the reformer to become FE from FS; and stopping the supply of the fuel to the reformer when an anode temperature becomes lower than the oxidative degradation temperature, where FE represents a flow rate of the fuel supplied to the reformer in a state in which the anode temperature is steady and lower than the oxidative degradation temperature, in which in the reformer the fuel is reformed and a reformed gas with a composition suitable to be supplied to an anode is produced, and in which an amount of the reformed gas produced is equal to or more than the requisite minimum flow rate for preventing the oxidative degradation of the anode when the anode temperature is a temperature equal to or higher than the oxidative degradation temperature, and FS represents a flow rate of the fuel supplied to the reformer at the start of the shutdown method. Also provided is an indirect internal reforming SOFC appropriate for this method.

A bookbinding structure for binding a stack of sheets including an elongated substrate having a first surface on which a first, heat activated, adhesive matrix is disposed and a second surface on which a second, pressure activated adhesive is disposed. The first adhesive matrix will be used to binding an edge of the stack so as to form a bound book with no cover. The second adhesive matrix includes first and second spaced-apart segments which extend along the length of the substrate. First and second release liners are disposed over the first and second adhesive segments, with the release liners remaining in place until the stack of sheets have been bound with the bookbinding structure. One of the release liners is manually removed from the bound stack and the stack is positioned in a cover assembly with the edge of the stack being positioned opposite a spine section of the cover assembly. The remaining release liner prevents the cover assembly from prematurely attaching to the stack thereby enabling the user to more easily positioned the stack with in the assembly. The user then forces the cover assembly against the exposed adhesive segment thereby securing part of the cover assembly to the stack. The second release liner is then removed and pressure is applied to that part of the cover assembly opposite the exposed segment thereby completing the binding sequence.

In contrast to slot-type gaming machines with their preset paylines designating predetermined array positions, the paylines of this novel wagering game are unknown until the indicia in the array have been selected. The indicia are selected from a variety of indicium types, each having a different number of members for identifying adjacent indicia. The randomly selected indicia determine the paylines, if any, in the array. Conditions may be imposed that limit the size and geometry of the paylines in this wagering game.

A guide piece projects from an outside surface of a cage bar of a cage so as to make sliding contact with a raceway surface of an outer ring. As the cage rotates, the guide piece operates to guide the rotation of the cage while removing an excess grease on the raceway surface and transferring the excess grease to axially opposite ends of the outer ring. The guide piece is formed with a through-hole extending from an inner periphery of the cage to an edge of the guide piece for supplying the lubricant from the inner periphery side of the cage to the raceway surface.

A bearing ring for a radial rolling bearing, in particular for a cylindrical roller bearing or needle bearing which has, on one of the radial surface areas thereof, a track for a set of cylindrical rolling bodies which are cageless or are guided by a cage and one or two guide flanges axially bounding the track of the rolling bodies is/are fastened to the axial end surfaces of said bearing by adhesive bonding. Each guide flange has a rectangular profile cross section with a horizontal fastening limb and a vertical flange limb and, by way of the horizontal fastening limb thereof, is adhesively bonded in an encircling axial groove in an axial end surface of the bearing ring. The width of each axial groove is greater than the material thickness of each fastening limb, and each guide flange can be fixed radially in position in the particular axial groove of a profiling of the fastening limb of said guide flange, the profiling being in contact both with the outer wall and with the inner wall of the associated axial groove.

There is provided a spindle motor including: a shaft connected directly or indirectly to a base member and having a depression groove formed in a central portion of an outer peripheral surface thereof; a sleeve rotatably installed on the shaft and having a communication hole formed so as to be connected to the depression groove; and a rotor hub fixedly installed on the sleeve to thereby rotate together therewith, wherein the communication hole is inclined so that lubricating fluid may be easily injected into the depression groove, and the sleeve has a fluid storage part formed on an outer peripheral surface thereof, the fluid storage part being connected to the communication hole and temporarily storing the lubricating fluid therein.

Communication facilitated between frames of a browser window. Whenever a particular frame receives a message destined for a target frame from a source frame, the particular frame determines if the particular is indeed the target frame. If so, the particular frame processes the message, but if not, the particular frame determines whether the target frame has registered with the particular frame. If the target frame has registered with the particular frame, the particular frame uses a handle communicated as part of the registration to dispatch the message further towards the target frame. In some cases, this handle may be directly that of the target frame itself, in which case the particular frame communicates the message directly with the target frame. This manner of inter-frame communication may be facilitated by a unique registration process when frames come into existence.

A mat with an upper road side and a lower ground contacting side, the mat comprising: a frame supporting one or more boards; and a grapple receiver formed in an interior portion of the mat and indented from one or both of the upper road side and the lower ground contacting side to allow grapple jaws to grip the grapple receiver between the grapple jaws.

A grinding attachment for highways and similar surfaces is disclosed for grinding operations closer to adjacent obstacles than is possible with existing equipment using a straddle-type centrally mounted grinding drum. The grinding attachment assembly comprises at one end a stub axle, which engages the grinding drum via a head extension. The stub axle is attached to a shroud which is in turn supported by a mounting assembly, which in operation attaches to a vehicle or machine able to drive the grinding attachment. The grinding drum can thereby operate proximal obstacles adjacent a grinding surface by virtue of arrangement of the stub axle, shroud and mounting assembly.

A computer-implemented method and computing system for identifying, using one or more computing devices, an appointment scheduled for at least one user. Some embodiments may include determining, using the one or more computing devices, a present location for the at least one user and generating, using the one or more computing devices, a reminder for the appointment based upon, at least in part, the present location.

A backlight module includes a carrier plate, a plurality of light sources, a plurality of circular Fresnel lenses, and a plurality of cylinder Fresnel lenses. The circular Fresnel lenses are arranged in an array form on the carrier plate. The light sources correspond to the circular Fresnel lenses, and are located in a side away from the carrier plate. One cylinder Fresnel lens is set between every two adjacent circular Fresnel lenses. A length direction of each cylinder Fresnel lens is parallel to an extending direction of adjacent column of the circular Fresnel lens. The circular and cylinder Fresnel lenses are used to reflect a light incident into their surfaces, and to increase an emission angle of the reflected light.

Computationally implemented methods and systems are described herein that are designed to, among other things, receiving a level-one encrypted output of a surveillance device; encrypting at least a part of the level-one encrypted output of the surveillance device with a level-two encryption key whose decryption key is inaccessible by a level-two encryption entity; and transmitting a level-two encrypted output of the surveillance device.

In accordance with this invention a binder composition for treating particulate material to form a solid aggregate matrix is prepared by providing a urea formaldehyde precondensate; a polar solvent; additional urea; an acid or salt thereof, the acid or salt thereof being selected such as to render the pH of the binder composition to a value from 2.0 to 5.3; providing a sugar; providing a binding promoter for enhancing the binding between the binder composition and the particulate material; and mixing the above so as to form a binder composition. The binder composition is mixed with particulate material and allowed to set into a solid aggregate matrix over a period of longer than 30 minutes from being mixed with the said particulate material.

The invention relates to a balancing device, having a measuring system for determining the rotational unbalance of a test object, comprising a spindle unit with a spindle, which is intended to hold the test object and rotate it at a test rotational speed, and a spindle mounting, by which the spindle unit is movably anchored on the machine base, such that the spindle unit can oscillate in a predetermined measuring direction as a result of the unbalance forces occurring during the measurement operation, and at least one sensor, which upon rotation of the spindle detects at least one unbalance characteristic variable occurring in the measuring direction, and a material removal system for balancing the test object by material removal in a predetermined site. The measuring system and the material removal system are designed such that material can be removed when the test object is held in the spindle.

An adjustable drill is provided comprising a drill body having at least one face surface with a plurality of serrations provided therewith. The drill further has at least one cartridge having a cooperating plurality of second serrations, to be driven with the drill body when assembled therewith. The at least one cartridge includes at least one insert pocket, and at least one insert is releasably affixed in the insert pocket provided in the cartridge. In further examples, the adjustable drill may have a central cutting system in combination with the adjustable cartridge type system, wherein the central cutting system may be modular. There may also be provided a modular type of holder arrangement to provide flexibility to adapt the system for various applications.

A rotating cylinder includes and a main body, a piston head, a piston rod and a guide assembly. The piston head slidably is received within the main body. The piston rod partially received within the main body, the piston head is fixed to the piston head, the piston rod defines one or more guiding groove adjacent to the piston head, the guiding groove includes a straight portion, a first helix portion and a second helix portion, the straight portion extends axially toward the piston head, the first helix portion curvedly extends away from the straight portion toward the piston head, the second helix portion curvedly extends from an end of the first helix portion toward a direction away from the piston head and the straight portion. The guide assembly is mounted on the main body and includes one or more guiding member slidably engaged with the guiding groove.

There are provided a substrate for an inkjet head and an inkjet head wherein in a case where a protection layer of heating resistors is energized, an electrical connection with portions around the protection layer is more reliably cut. A first protection layer provided for the substrate for an inkjet head includes individual sections provided at positions corresponding to the plurality of heating resistors and a common section which commonly connects the plurality of individual sections. The individual sections and the common section are connected via connect sections which are eluted and connect in a case where an electrochemical reaction occurs between the connect sections and ink when electricity flow therethrough, so that an electrical connection between the individual sections and the common section is cut.

An inductive power outlet for providing power to an electric load via an inductive power receiver includes at least one primary inductive coil wired to a power supply via a driver configured to provide a driving voltage across the primary inductive coil such that a secondary voltage is induced in a secondary inductive coil associated with the inductive power receiver. The driver may include a controller configured to receive feedback control signals from the inductive power receiver indicating if more or less power is required. The controller may be further configured to adjust the driving voltage according to the control signals.

A transfer switch configured to detect a ground current is configured to selectively connect a first power source or a second power source to a load. Each of the power sources includes at least one “hot” lead and one neutral lead, and the transfer switch is configured to switch both the “hot” and the neutral leads. If the neutral switching portion of the transfer switch fails, current may be supplied to the load via the “hot” lead of one of the power sources and return from the load via a ground conductor and the neutral lead of the other power source. The transfer switch includes a current sensor, detecting current on the ground conductor, in order to detect such a condition. The signal from the current sensor is provided to a control circuit, which, in turn, activates an indicator if the current on the ground conductor exceeds a predefined level.

A power distribution system for distributing electric power generated by a wind farm between an AC power transmission link and a DC power transmission link is provided. Both power transmission links connect the wind farm to a substation of a power grid. The power distribution system includes a central wind farm controller and a distribution device. In response to a control signal from the central wind farm controller, the distribution device distributes the generated electrical power between the two power transmission links. It is further described a power transmission system with the above described power distribution system and a method for distributing electric power between an AC power transmission link and a DC power transmission link.

A circuit and method for wirelessly coupling an electrical energy between an electrical energy source and at least one load is provided. The circuit comprises a primary unit and at least one secondary unit. The primary unit includes an input node for receiving an input voltage produced by the energy source; a transmitter circuit including a transmitter coil configured to generate an electromagnetic field; and a regulator. The regulator is configured to sense a current consumption of the primary unit, determine a gradient of the current consumption with respect to different input voltages, and determine an optimal input voltage based on the gradient. The at least one secondary unit comprises a receiver circuit and a load. The receiver unit includes a coil that wirelessly and inductively couples with the electromagnetic field of the primary unit to receive power therefrom. The receiver unit further includes a regulator circuit configured to provide a constant power to an output node.

A system for electrical braking of a vehicle comprises a power bus coupled to a first driver associated with a first electromechanical actuator (EMA). The power bus is also coupled to a second driver associated with a second EMA, and the first EMA and the second EMA are associated with a wheel of the vehicle. The power bus provides braking power to the first EMA via the first driver and to the second EMA via the second driver. A normal braking command interface provides a first braking signal to the first driver and a second braking signal to the second driver. An emergency/park brake interface bypasses the normal braking command interface and sends a first emergency/park braking signal to the first driver and a second emergency/park braking signal to the second driver. A sensor measures a current at a single location of the power bus that is proportional to a braking force exerted on the wheel.

A circuit includes a comparator having input terminals configured to be coupled across a drive transistor adapted to drive a phase of a motor. The comparator senses a drive current of the motor phase, said sensed drive current represented by a periodic signal whose period is indicative of motor speed. A motor speed calculation circuit receives the periodic signal and processes the periodic signal to determine a speed of the motor.

A drive section for a substrate transport arm including a frame, at least one stator mounted within the frame, the stator including a first motor section and at least one stator bearing section and a coaxial spindle magnetically supported substantially without contact by the at least one stator bearing section, where each drive shaft of the coaxial spindle includes a rotor, the rotor including a second motor section and at least one rotor bearing section configured to interface with the at least one stator bearing section, wherein the first motor section is configured to interface with the second motor section to effect rotation of the spindle about a predetermined axis and the at least one stator bearing section is configured to effect at least leveling of a substrate transport arm end effector connected to the coaxial spindle through an interaction with the at least one rotor bearing section.

A front loader is provided with an indicator device. The indicator device is configured to indicate that the work implement is in an identical posture irrespective of a height position of the work implement, by aligning a rear end of the indicator rod with a rear end of the guide tube.

A communication process between two constitutive elements of the network of electricity distribution in a domestic or industrial premise including circuit breakers, electrical modules, switches, electrical plugs and light connection devices. The process including the following steps: assignment by a protocol such as DHCP, BootP or RARP of a first IP address to a first element of the power distribution network, assignment of a second IP address to a second element, and establishment of a communication between the first and second elements of the power distribution network.

Disclosed are polyvalent macromolecules, compositions comprising the macromolecules, and methods of use. The polyvalent macromolecules have a polymer backbone and pendent groups attached to the polymer backbone. Some or all of the pendent groups have optionally a linker, a surface-seeking group capable of binding strongly to a metal surface, and a spectroscopically detectable chromophore detectable.

The invention provides a binding layer comprising a polysaccharide substituted by carboxylic groups or derivatives thereof exhibiting high performance in the binding of ligand molecules and in the interaction thereof with analyte molecules. A method for the preparation of the binding layer and for the assaying of various analyte molecules is also provided.

The novel metallocenes of the formula I in which, preferably, M1 is Zr or Hf, R1 and R2 are alkyl or halogen, R3 and R4 are hydrogen, R5 and R6 are alkyl or haloalkyl, —(CR8R9)m—R7—(CR8R9)n— is a single- or multi-membered chain in which R7 may also be a (substituted) hetero atom, m+n is zero or 1, and R10 is hydrogen, form, together with aluminoxanes as cocatalysts, a very effective catalyst system for the preparation of polyolefins of high stereospecificity and high melting point.

A dual function binding machine for making journal notebooks at home includes a hole punching mechanism and a binding mechanism. A punch die includes a plurality of rectangular punch teeth in a graduated configuration to minimize the amount of force required to penetrate through the journal book materials. A guide provides different positions for punching through covers, inner pages and continuous punching of both. This allows the perfect alignment and fit of the outside covers with the inside pages. A spring biased lever operates the punch die in a horizontal direction. The binding mechanism included in the same machine has a vertical outer vise wall that is horizontally movable to compress the binding material to the pages and covers of the journal notebook.

A viewfinder 3 includes a finder optical system S2 including first and second lens groups L1, L2; a zoom frame 6 provided with first and second cam grooves 63, 64 configured to rotate about an optical axis A2 to move the first and second lens groups L1, L2 in the optical axis direction in accordance with the shapes of the first and second cam grooves 63, 64; and a diopter adjuster 9 configured to adjust the diopter of the finder optical system S2. The diopter adjuster 9 changes the position of the zoom frame 6 in the optical axis direction to adjust the diopter of the finder optical system S2, and adjusts, during rotation of the zoom frame 6, the position of the zoom frame 6 in the optical axis direction such that the diopter of the finder optical system S2 is maintained.

The laser mount arrangement can have a laser bar and a driver positioned adjacent to one another and secured against a connection face of a heat sink base. The heat sink base is connected to and forms a first electrical connection between the laser bar and the driver. A second electrical connection is also provided between the laser bar and the driver opposite the heat sink base, which can be in the form of a flexible metal sheet with a narrow upward fold. This arrangement can provide a low inductance path for the current.

A bookbinding apparatus for producing a booklet by coating an adhesive onto a back side of a bundle of sheets and by pasting a book cover onto the back side of the bundle of sheets, comprises: an oblique cutout portion forming section to form a cutout on an edge of each sheet of the bundle of sheets in such a way that an oblique cutout portion is formed along the width of the back side of the bundle of sheets; a sheet bundle accommodating section to accommodate the bundle of sheets on which the oblique cutout portion is formed; a coating section to coat an adhesive on the back side of the bundle of sheets accommodated in the sheet bundle accommodating section; and a bookbinding section to paste a book cover on the adhesive-coated back side of the bundle of sheets so as to produce the booklet.

Proposed is an image processing apparatus in which the data processing method is changed over in suitable fashion in accordance with job settings when binding is performed. To accomplish this, the image processing apparatus is such that when stored image data is processed, the output format is determined from a job ticket and processing for dividing image data is controlled in accordance with the output format determined. In accordance with the output format determined, the apparatus changes over the output timing of divided page image data.

A notch forming device, comprises a notch forming section to form a notch on an edge of a sheet constituting a sheet bundle to be outputted in accordance with an execution of a job; a shifting section to shift a position of a notch to be formed on a sheet by the notch forming section; and a control section to control the shifting section. When plural sheet bundles are outputted in accordance with the execution of the job, the control section controls the shifting section to make a position of a notch on a leading sheet of each sheet bundle at the same position.

A machine for binding a packet of sheets of binding elements has a transfer belt designed to magnetically fix the binding elements and to move between a disengagement position in which it receives the binding elements and an engagement position in which it is positioned in a closure zone, closure devices disposed upstream of the transfer belt and designed, in the closure zone, to close the elements, a magnetic binding table disposed upstream of the closure devices, and comprising a fixing zone for holding a series of ends of the elements, and a magnetic top guide disposed upstream of the closure devices and above the binding table, and comprising a fixing zone for holding the other series of ends of the elements, the packet of perforated sheets being inserted between the table and the top guide.

An image forming system including a control section provides control in such a way that, the ring binder of the size determined for the first set of copies is adopted so that ring binding is performed for a second set of copies or copies thereafter in a case of executing a job for ring binding of a plurality of copies. When at least one of a status change in the sheet feed section, a main power source being turned off, or a change in a job ticket is occurred from a suspension to a resumption of the job, since the thickness of a bundle of sheets may change, the thickness measuring section is caused to measure the thickness of the bundle in a first set of copies subsequent to resumption. And the control section judges continuation or suspension of a job.

A method and system for on-demand book production is provided in which covers and book content are synchronized at book binding equipment. In one exemplary system and method, a single printer prints a book cover followed by its corresponding book block. The cover and book block are each sequentially staged and synchronized together for binding in the binding equipment. In another method and system for on-demand book production, covers are printed and encoded at a first printer and a book block printing instruction is initiated in response to decoding of the cover in the binding equipment. Printing of the book block is in a separate but integrated printer and the book block is fed to the binding equipment for binding with the book cover. In each instance, synchronized book covers and book blocks are bound in and output from the binding equipment.

Apparatus is disclosed for controlling the depth of a layer of a layer of adhesive on a peripheral surface of a rotary member (e.g., a wheel) for the application of the adhesive to an object. The apparatus comprises a heated reservoir containing a supply of hot melt adhesive maintained within a desired temperature range, where the rotary member is partially immersed in the adhesive and is rotated by a motor such that the as the rotary member is rotated up out of the peripheral surface of the rotary member has the layer of adhesive thereon. A computer controls system controls the motor such that the speed of the rotary member may be increased or decreased so as to vary the depth of the adhesive on the peripheral surface of the rotary member.