amp Behind the campaign promises - Health and social care spending By feeds.bmj.com Published On :: Fri, 22 Nov 2019 16:21:30 +0000 A UK general election has been called - polling day is on the 12th of December, and from now until then we’re going to be bringing you a weekly election-themed podcast. We want to help you make sense of the promises and pledges, claims and counter-claims, that are being made around healthcare and the NHS out on the campaign trail. This week... Full Article
amp Behind the campaign promises - Health beyond the NHS By feeds.bmj.com Published On :: Sat, 30 Nov 2019 09:10:48 +0000 A UK general election has been called - polling day is on the 12th of December, and from now until then we’re going to be bringing you a weekly election-themed podcast. We want to help you make sense of the promises and pledges, claims and counter-claims, that are being made around healthcare and the NHS out on the campaign trail. This week... Full Article
amp Behind the campaign promises - what the NHS means for the election By feeds.bmj.com Published On :: Thu, 05 Dec 2019 19:09:30 +0000 UK general election has been called - polling day is on the 12th of December, and from now until then we’re going to be bringing you a weekly election-themed podcast. We want to help you make sense of the promises and pledges, claims and counter-claims, that are being made around healthcare and the NHS out on the campaign trail. This week we're... Full Article
amp Behind the campaign promises - Doctors in parliament By feeds.bmj.com Published On :: Mon, 09 Dec 2019 18:52:26 +0000 The UK general election is happening this week, and you’ve probably made your mind up which MP you’re voting for already - and maybe the NHS has influenced that decision. This year has seen an increase in the number of doctors running for parliament, and in this podcast we find out what motivates doctors to step away from clinical practice, and... Full Article
amp Talk Evidence - digital clubbing, osteoarthritis & sustainable EBM By feeds.bmj.com Published On :: Mon, 16 Dec 2019 19:36:54 +0000 We’re back for the December Talk Evidence, and this month we’re being very digital Firstly,(1.20) Helen tells us about arthritic fingers - should we be using prednisolone for treatment when people have painful osteoarthritis of the hand Then (13.30) Carl gets us all to check our fingers for clubbing, and we find out how useful it is as a test... Full Article
amp 5' AMP-activated protein kinase activation causes GLUT4 translocation in skeletal muscle By diabetes.diabetesjournals.org Published On :: 1999-08-01 EJ Kurth-KraczekAug 1, 1999; 48:1667-1671Articles Full Article
amp Evidence for 5'AMP-Activated Protein Kinase Mediation of the Effect of Muscle Contraction on Glucose Transport By diabetes.diabetesjournals.org Published On :: 1998-08-01 Tatsuya HayashiAug 1, 1998; 47:1369-1373Rapid Publications Full Article
amp Triggering and amplifying pathways of regulation of insulin secretion by glucose By diabetes.diabetesjournals.org Published On :: 2000-11-01 JC HenquinNov 1, 2000; 49:1751-1760Articles Full Article
amp Too close for comfort - St Mary families in cramped homes have eyes on virus By jamaica-gleaner.com Published On :: Fri, 08 May 2020 00:26:06 -0500 Sandra Ferguson resides with her children and grandchildren in a concrete dwelling that is sectioned into four living quarters in the Fort George Road area of Annotto Bay. With 10 of them sharing kitchen and bathroom facilities, Ferguson said... Full Article
amp Scotiabank – a loose vampire By jamaica-gleaner.com Published On :: Sat, 09 May 2020 00:06:30 -0500 THE EDITOR, Madam: On May 5, 2020, at about 8:40 a.m., I went completely berserk, telling two staff members of the Bank of Nova Scotia from the Liguanea branch some proper Jamaica vernaculars, long like the Holland Bamboo. I was astonished by my... Full Article
amp Lauren Campbell – basking in shades of creativity By jamaica-gleaner.com Published On :: Sun, 26 Apr 2020 00:16:37 -0500 She’s what you’d term the consummate creative – through the sensory ‘dry land tourist’ tales of her ‘Right Roun Di Corna’ blog to the pieces in her JadeLauren eyewear brand, Lauren Campbell is colouring the world with beauty, life, and bomb... Full Article
amp n-3 Fatty Acid and Its Metabolite 18-HEPE Ameliorate Retinal Neuronal Cell Dysfunction by Enhancing Müller BDNF in Diabetic Retinopathy By diabetes.diabetesjournals.org Published On :: 2020-03-20T11:50:29-07:00 Diabetic retinopathy (DR) is a widespread vision-threatening disease, and neuroretinal abnormality should be considered as an important problem. Brain-derived neurotrophic factor (BDNF) has recently been considered as a possible treatment to prevent DR-induced neuroretinal damage, but how BDNF is upregulated in DR remains unclear. We found an increase in hydrogen peroxide (H2O2) in the vitreous of patients with DR. We confirmed that human retinal endothelial cells secreted H2O2 by high glucose, and H2O2 reduced cell viability of MIO-M1, Müller glia cell line, PC12D, and the neuronal cell line and lowered BDNF expression in MIO-M1, whereas BDNF administration recovered PC12D cell viability. Streptozocin-induced diabetic rats showed reduced BDNF, which is mainly expressed in the Müller glia cell. Oral intake of eicosapentaenoic acid ethyl ester (EPA-E) ameliorated BDNF reduction and oscillatory potentials (OPs) in electroretinography (ERG) in DR. Mass spectrometry revealed an increase in several EPA metabolites in the eyes of EPA-E–fed rats. In particular, an EPA metabolite, 18-hydroxyeicosapentaenoic acid (18-HEPE), induced BDNF upregulation in Müller glia cells and recovery of OPs in ERG. Our results indicated diabetes-induced oxidative stress attenuates neuroretinal function, but oral EPA-E intake prevents retinal neurodegeneration via BDNF in Müller glia cells by increasing 18-HEPE in the early stages of DR. Full Article
amp This is the D-backs prospect to watch in camp By mlb.mlb.com Published On :: Mon, 4 Feb 2019 21:10:42 EDT The countdown to pitchers and catchers reporting is down to single digits for all 30 MLB clubs, but as exciting as it is to see the return of Major League stars, it's also a time to dream about the next wave of baseball talent. Full Article
amp Greinke arrives at D-backs camp By mlb.mlb.com Published On :: Fri, 15 Feb 2019 19:05:12 EDT D-backs ace Zack Greinke reported to Salt River Fields on Friday after missing the first two days of pitcher and catcher workouts. Full Article
amp 'Campfire drill' helps pitchers, catchers bond By mlb.mlb.com Published On :: Fri, 15 Feb 2019 18:39:10 EDT After seeing improved communication between pitchers and catchers last year, the "campfire" drill was put back on the D-backs' schedule and took place Friday at Salt River Fields. Full Article
amp Sagicor raises doubt about Scotia Life T&T deal By jamaica-gleaner.com Published On :: Fri, 08 May 2020 00:09:28 -0500 Sagicor Finance Company has raised doubt about whether the deal to acquire the assets of Scotia Life Trinidad... Full Article
amp SVL ramping up online games By jamaica-gleaner.com Published On :: Fri, 08 May 2020 00:18:10 -0500 SUPREME VENTURES Limited, SVL, has locked down its Acropolis gaming lounge since March 18, when the Government mandated the closure of all lounges and bars. Sports wagering has fallen precipitously, concomitant with the suspension of sporting... Full Article
amp 13th Annual Immigration Law & Policy Conference By www.migrationpolicy.org Published On :: Wed, 20 Jul 2016 11:36:58 -0400 With issues of immigration policy very much at the forefront of the 2016 elections, this annual conference offers policy and legal analysis on key immigration topics facing the country and the incoming administration and Congress in 2017. Full Article
amp 13th Annual Immigration Law & Policy Conference By www.migrationpolicy.org Published On :: Wed, 28 Sep 2016 15:39:09 -0400 The 13th annual Immigration Law & Policy Conference offered policy and legal analysis on key immigration topics, including: the election and the future of immigration policy; refugee resettlement in the United States; immigration detention and enforcement; and the impacts of the Supreme Court opinion in the important U.S. vs Texas case Full Article
amp Trump Administration Makes Down Payment on Campaign Pledges to Address Illegal Immigration By www.migrationpolicy.org Published On :: Thu, 14 Dec 2017 13:17:21 -0500 In its first year, the Trump administration moved to deliver on some of Donald Trump’s campaign promises on immigration, including ramping up enforcement in the U.S. interior and ending the Deferred Action for Childhood Arrivals (DACA) program. The administration also announced the termination of Temporary Protected Status (TPS) for nationals of some countries. This article explores some of the top policy changes. Full Article
amp Shaping a Narrative of "Crisis" at Border, Trump Administration Takes Muscular Action By www.migrationpolicy.org Published On :: Tue, 18 Dec 2018 16:06:51 -0500 The Trump administration took sweeping action in 2018 to slow legal immigration, make life harder for some immigrants already in the United States, rebuff would-be asylum seekers, and reduce refugee resettlement. Shaping a narrative of crisis at the border, the administration significantly changed the U.S. asylum system, deployed troops and tear gas, and separated families—yet Central American migrants continued to arrive. Full Article
amp Will Immigration Reform Ever Succeed Again? The Legacy of IRCA & Its Enduring Lessons By www.migrationpolicy.org Published On :: Wed, 26 Jun 2019 13:38:21 -0400 This discussion on the 1986 Immigration Reform and Control Act (IRCA) showcases MPI Fellow Charles Kamasaki's book, Immigration Reform: The Corpse That Will Not Die. Kamasaki is joined by other veterans of the IRCA debate for a conversation on the lessons, the intended and unintended consequences, and how the law’s legacy has shaped contemporary politics on immigration. Full Article
amp What's New in Farm Labor? Immigration and the Agricultural Sector By www.migrationpolicy.org Published On :: Wed, 26 Aug 2015 12:12:00 -0400 An expert discussion on the findings of the National Agricultural Workers Survey (NAWS) related to immigrants, along with an overview of farm labor in 2015 and discussion on how current and possible future immigration policies might impact immigrant workers in the agricultural sector. Full Article
amp What's New in Farm Labor? Immigration and the Agricultural Sector By www.migrationpolicy.org Published On :: Wed, 16 Sep 2015 12:18:47 -0400 An expert discussion on the findings of the National Agricultural Workers Survey (NAWS) related to immigrants, along with an overview of farm labor in 2015 and discussion on how current and possible future immigration policies might impact immigrant workers in the agricultural sector. Full Article
amp Plasma Lipidome and Prediction of Type 2 Diabetes in the Population-Based Malmö Diet and Cancer Cohort By care.diabetesjournals.org Published On :: 2020-01-20T12:00:30-08:00 OBJECTIVE Type 2 diabetes mellitus (T2DM) is associated with dyslipidemia, but the detailed alterations in lipid species preceding the disease are largely unknown. We aimed to identify plasma lipids associated with development of T2DM and investigate their associations with lifestyle. RESEARCH DESIGN AND METHODS At baseline, 178 lipids were measured by mass spectrometry in 3,668 participants without diabetes from the Malmö Diet and Cancer Study. The population was randomly split into discovery (n = 1,868, including 257 incident cases) and replication (n = 1,800, including 249 incident cases) sets. We used orthogonal projections to latent structures discriminant analyses, extracted a predictive component for T2DM incidence (lipid-PCDM), and assessed its association with T2DM incidence using Cox regression and lifestyle factors using general linear models. RESULTS A T2DM-predictive lipid-PCDM derived from the discovery set was independently associated with T2DM incidence in the replication set, with hazard ratio (HR) among subjects in the fifth versus first quintile of lipid-PCDM of 3.7 (95% CI 2.2–6.5). In comparison, the HR of T2DM among obese versus normal weight subjects was 1.8 (95% CI 1.2–2.6). Clinical lipids did not improve T2DM risk prediction, but adding the lipid-PCDM to all conventional T2DM risk factors increased the area under the receiver operating characteristics curve by 3%. The lipid-PCDM was also associated with a dietary risk score for T2DM incidence and lower level of physical activity. CONCLUSIONS A lifestyle-related lipidomic profile strongly predicts T2DM development beyond current risk factors. Further studies are warranted to test if lifestyle interventions modifying this lipidomic profile can prevent T2DM. Full Article
amp Look: Dangling raccoon rescued from under California highway on-ramp By www.upi.com Published On :: Fri, 08 May 2020 15:08:05 -0400 Animal rescuers in California said they reached over the side of a freeway on-ramp to rescue a raccoon seen dangling from a metal beam under the ramp. Full Article
amp Leukocyte Telomere Length, DNA Oxidation, and Risk of Lower-Extremity Amputation in Patients With Long-standing Type 1 Diabetes By care.diabetesjournals.org Published On :: 2020-03-20T11:50:34-07:00 OBJECTIVE Telomere shortening and DNA oxidation are associated with premature vascular aging, which may be involved in lower-extremity amputation (LEA). We sought to investigate whether leukocyte telomere length (LTL) and plasma 8-hydroxy-2'-deoxyguanosine (8-OHdG), a biomarker of DNA oxidation, were associated with LEA in subjects with type 1 diabetes at high vascular risk. RESEARCH DESIGN AND METHODS LTL (quantitative PCR) and plasma 8-OHdG concentrations (immunoassay method) were assessed at baseline in the GENEDIAB (Génétique de la Néphropathie Diabétique) type 1 diabetes cohort. Logistic and Cox proportional hazards regression models were fitted to estimate odds ratio (OR) (at baseline) and hazard ratio (HR) (during follow-up), with related 95% CI, by increasing biomarker tertiles (T1, T2, T3). RESULTS Among 478 participants (56% male, mean ± SD age 45 ± 12 years and diabetes duration 29 ± 10 years), 84 patients had LEA at baseline. Baseline history of LEA was associated with shorter LTL (OR for T2 vs. T1 0.62 [95% CI 0.32–1.22] and for T3 vs. T1 0.41 [0.20–0.84]) but not with plasma 8-OHdG (1.16 [0.56–2.39] and 1.24 [0.61–2.55], respectively). New cases of LEA occurred in 34 (12.3%) participants during the 10-year follow-up. LTL were shorter (HR T2 vs. T1 0.25 [95% CI 0.08–0.67] and T3 vs. T1 0.29 [0.10–0.77]) and plasma 8-OHdG higher (2.20 [0.76–7.35] and 3.11 [1.07–10.32]) in participants who developed LEA during follow-up compared with others. No significant interaction was observed between biomarkers on their association with LEA. CONCLUSIONS We report the first independent association between LTL shortening and excess risk of LEA in type 1 diabetes. High plasma 8-OHdG was also associated with incident LEA but partly dependent on cofounding variables. Full Article
amp A New Migration Policy for A New Era: A Conversation with Mexico's Interior Secretary Olga Sánchez Cordero By www.migrationpolicy.org Published On :: Thu, 28 Feb 2019 14:38:21 -0500 On her first official trip to Washington, DC, Secretary of the Interior Olga Sánchez Cordero offered a public address on Mexico’s new approach to migration policy at MPI. Her remarks and the event discussion were mostly conducted in Spanish, and this recording is of the simultaneous English interpretation. Full Article
amp Dentists rank No. 2 in U.S. News & World Report’s Best Jobs report By www.ada.org Published On :: Tue, 14 Jan 2020 07:58:00 -0600 Dentists leaped up to No. 2 in U.S. News & World Report’s annual rankings of the 100 Best Jobs, the magazine revealed on its website Jan. 7. Full Article
amp Texas A&M dental school opens new clinic, education building By www.ada.org Published On :: Tue, 21 Jan 2020 10:14:00 -0600 Texas A&M College of Dentistry announced Jan. 17 it opened it’s a new 160,000-square-foot, nine-story clinic, which enables the dental school to increase underserved patients’ access to care. Full Article
amp Tampa Bay Lightning team dentist puts players’ mouths back together again By www.ada.org Published On :: Thu, 27 Feb 2020 09:54:00 -0600 When Dr. Gil Rivera became a dentist, he had no idea his career would take him to the bloodied and bruised front lines of the NHL, but nearly 18 years later, he continues to treat the ravaged mouths of professional hockey players as the team dentist of the Tampa Bay Lightning. Full Article
amp Association launches new ADA Science & Research Institute By www.ada.org Published On :: Thu, 12 Mar 2020 08:07:00 -0500 The American Dental Association launched the new ADA Science & Research Institute LLC on Jan. 1, bringing together the Science Institute in Chicago and research group in Gaithersburg, Maryland, that previously reported to the ADA Foundation. Full Article
amp ADA initiates grassroots campaign in response to CARES Act By www.ada.org Published On :: Sun, 22 Mar 2020 18:47:00 -0500 The ADA is calling on dentists everywhere to contact their legislators today ahead of the Senate’s vote on the Coronavirus Aid, Relief and Economic Security Act. Full Article
amp Breaking New Ground: Ten Ideas to Revamp Integration Policy in Europe By www.migrationpolicy.org Published On :: Wed, 23 Jan 2019 10:00:37 -0500 To address the intersecting challenges facing European societies—from population aging and labor-market change, to immigration and political upheaval—governments need to hone new strategies for helping both newcomers and long-term residents succeed amid diversity. This report explores some of the most promising approaches, drawing on input from policymakers, the private sector, civil society, and others. Full Article
amp Strict Preanalytical Oral Glucose Tolerance Test Blood Sample Handling Is Essential for Diagnosing Gestational Diabetes Mellitus By care.diabetesjournals.org Published On :: 2020-04-29T13:46:01-07:00 OBJECTIVEPreanalytical processing of blood samples can affect plasma glucose measurement because on-going glycolysis by cells prior to centrifugation can lower its concentration. In June 2017, ACT Pathology changed the processing of oral glucose tolerance test (OGTT) blood samples for pregnant women from a delayed to an early centrifugation protocol. The effect of this change on the rate of gestational diabetes mellitus (GDM) diagnosis was determined.RESEARCH DESIGN AND METHODSAll pregnant women in the Australian Capital Territory (ACT) are recommended for GDM testing with a 75-g OGTT using the World Health Organization diagnostic criteria. From January 2015 to May 2017, OGTT samples were collected into sodium fluoride (NaF) tubes and kept at room temperature until completion of the test (delayed centrifugation). From June 2017 to October 2018, OGTT samples in NaF tubes were centrifuged within 10 min (early centrifugation).RESULTSA total of 7,509 women were tested with the delayed centrifugation protocol and 4,808 with the early centrifugation protocol. The mean glucose concentrations for the fasting, 1-h and 2-h OGTT samples were, respectively, 0.24 mmol/L (5.4%), 0.34 mmol/L (4.9%), and 0.16 mmol/L (2.3%) higher using the early centrifugation protocol (P < 0.0001 for all), increasing the GDM diagnosis rate from 11.6% (n = 869/7,509) to 20.6% (n = 1,007/4,887).CONCLUSIONSThe findings of this study highlight the critical importance of the preanalytical processing protocol of OGTT blood samples used for diagnosing GDM. Delay in centrifuging of blood collected into NaF tubes will result in substantially lower rates of diagnosis than if blood is centrifuged early. Full Article
amp "Merit-Based" Immigration: Designing Successful Selection Systems By www.migrationpolicy.org Published On :: Fri, 17 May 2019 16:51:28 -0400 With the U.S. administration calling for the United States to adopt a more “merit-based” immigrant selection system, this conversation focused on what policymakers should consider in designing—and managing—immigrant selection systems in a time of intense labor-market and demographic change. Full Article
amp Migration & Coronavirus: A Complicated Nexus Between Migration Management and Public Health By www.migrationpolicy.org Published On :: Thu, 19 Mar 2020 10:35:46 -0400 This webinar, organized by MPI and the Zolberg Institute on Migration and Mobility at The New School, discussed the state of play around the globe surrounding COVID-19 and examined where migration management and enforcement tools may be useful and where they may be ill-suited to advancing public health goals. Full Article
amp Curbing the Influence of "Bad Actors" in International Migration (Transatlantic Council Statement) By www.migrationpolicy.org Published On :: Sat, 01 Feb 2014 00:00:00 -0500 This Transatlantic Council on Migration Statement assesses the continuum of policies needed to disrupt illegal migration-related activities and addresses the conditions that make them possible. It examines the role of migration "bad actors"—human traffickers and unscrupulous employers, among them—who operate and profit in this environment, and considers how governments can deploy resources to discourage their actions. Full Article
amp Will Immigration Reform Ever Succeed Again? The Legacy of IRCA & Its Enduring Lessons By www.migrationpolicy.org Published On :: Wed, 12 Jun 2019 12:34:22 -0400 This provocative discussion showcases Charles Kamasaki's book, Immigration Reform: The Corpse That Will Not Die, and explores the lessons that can be learned from the Immigration Reform and Control Act of 1986, its intended and unintended consequences, and how the law’s legacy has shaped contemporary politics surrounding immigration. Full Article
amp On This Day, May 9: Freighter collapses Tampa Bay bridge, killing 35 By www.upi.com Published On :: Sat, 09 May 2020 03:00:06 -0400 On May 9, 1980, a Liberian freighter rammed a bridge in Florida's Tampa Bay, collapsing part of the span and dropping 35 people to their deaths. Full Article
amp Entertainer Roy Horn of Siegfried & Roy dies of COVID-19 complications at 75 By www.upi.com Published On :: Sat, 09 May 2020 08:39:06 -0400 German-born entertainer Roy Uwe Ludwig Horn, one half of the stage duo Siegfried & Roy, has died of complications from the coronavirus. He was 75. Full Article
amp "Merit-Based" Immigration: Designing Successful Selection Systems By www.migrationpolicy.org Published On :: Thu, 09 May 2019 15:57:37 -0400 MPI and OECD experts discuss what policymakers should consider in designing and managing immigrant selection systems in a time of intense labor-market and demographic change. Full Article
amp “Merit-Based” Immigration: Trump Proposal Would Dramatically Revamp Immigrant Selection Criteria, But with Modest Effects on Numbers By www.migrationpolicy.org Published On :: Thu, 30 May 2019 10:20:09 -0400 The Trump administration’s plan to create a "merit-based" U.S. immigration system, lessening the longstanding focus on family reunification in favor of more economic migrants, has met with a lackluster response from Democrats and Republicans alike. This Policy Beat article explores how the Trump proposal would reshape immigration to the United States, and how it compares to selection systems in other countries and past debates about changing the U.S. system. Full Article
amp [ Cell Phones & Plans ] Open Question : What is the closest android equivalent to the 1st generation iPhone SE? By answers.yahoo.com Published On :: Sat, 09 May 2020 17:15:19 +0000 I am torn, I know it is time to upgrade my phone, but I don't know whether to upgrade to just accept the larger phone size and go with the 2nd gen SE or go with an android. I'd be interested to know what the closest equivalent android device there is to the 1st gen SE. I am open to a bigger screen size, but not a bigger phone. So, if there was an andriod that was all screen on the front, but was similar size to the original SE, I would be open to that. Full Article
amp [ Religion & Spirituality ] Open Question : Christians, why do some people keep lying by saying trans been using other Gender's room for long time but that lie? By answers.yahoo.com Published On :: Sat, 09 May 2020 17:15:22 +0000 i even got this from pro trans page that say they have laws banning men from women's room & trans aka GD was put into mad house, & even then there been alot of time where rapists &perverted freaks been using other Gender's bath room too doesn't make it right, they go to prison if they find out Full Article
amp [ Singles & Dating ] Open Question : Muslim man looking for relief? By answers.yahoo.com Published On :: Sat, 09 May 2020 17:15:23 +0000 I know it's Ramadan, but I've been feeling urges for a few years now and it's just getting more and more now. I always imagine about sex and loving my to-be wife. Right now, I'm studying medicine, so my parents told me it's too early to get married (24 years old). I just don't know really what to do. I prone masturbate to get some relief. What should I do? Full Article
amp [ Polls & Surveys ] Open Question : Poll: Is it okay if I make love to my gin and tonic instead ? By answers.yahoo.com Published On :: Sat, 09 May 2020 17:16:07 +0000 It's lockdown after all. Full Article
amp [ Earth Sciences & Geology ] Open Question : Are earthquakes necessary to release the earth's energy? By answers.yahoo.com Published On :: Sat, 09 May 2020 17:16:34 +0000 Full Article
amp [ Law & Ethics ] Open Question : Law and Ethics: Do you think gore should be illegal? By answers.yahoo.com Published On :: Sat, 09 May 2020 17:16:44 +0000 I certainly do, it doesn't make sense how someone crazy recording someone getting killed isn't illegal but CP is! That shouldn't be because, they should be either running away or trying to stop that super duper crazy person. Why can't both of them be illegal? Full Article
amp [ Religion & Spirituality ] Open Question : Does God love it when you call him Big Poppa? By answers.yahoo.com Published On :: Sat, 09 May 2020 17:17:49 +0000 Full Article