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[ASAP] Accelerated Protein Folding Using Greedy-Proximal A*

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01194




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French Open ticket holders to get refund

The French Tennis Federation says it will refund tickets purchased for the French Open because of uncertainty related to the coronavirus pandemic.




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Lead with Heart in Mind: Treading the Noble Eightfold Path for Mindful and Sustainable Practice / Joan Marques

Online Resource




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Saint Patrick retold: the legend and history of Ireland's patron saint / Roy Flechner

Online Resource




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Sensation and perception / E. Bruce Goldstein and James R. Brockmole

Hayden Library - QP431.G64 2017




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Creativity: the human brain in the age of innovation / by Elkhonon Goldberg

Hayden Library - QP376.G65 2018




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Arterial chemoreceptors: new directions and translational perspectives / Estelle B. Gauda, Maria Emilia Monteiro, Nanduri Prabhakar, Christopher Wyatt, Harold D. Schultz, editors

Online Resource




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The old drift: a novel / Namwali Serpell

Hayden Library - PR9405.9.S37 O53 2019




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The short plays / Harold Pinter ; with a foreword by Antonia Fraser

Lewis Library - PR6066.I53 A6 2018




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With no fresh content, broadcasters rely on old classics, web shows to entertain viewers

Confined to her home during the lockdown, Gwalior-based 37-year old Mansha Kasture is reliving childhood memories with her 8 year-old daughter, Mishika, watching Ramanand Sagar’s epic 'Ramayana' on DD National.




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Socio-Spatial Inequalities in Contemporary Cities [electronic resource] / by Alfredo Mela, Alessia Toldo

Mela, Alfredo, author




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The "democratic soldier" [electronic resource] : comparing concepts and practices in Europe / Sabine Mannitz

Mannitz, Sabine




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Cooldrink and Culture [electronic resource]




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Gold(III) bis(dithiolene) complexes: from molecular conductors to prospective anticancer, antimicrobial and antiplasmodial agents

Metallomics, 2020, Accepted Manuscript
DOI: 10.1039/D0MT00064G, Paper
Diana Fontinha, Silvia Andreia Sousa, Tânia S. Morais, Miguel Prudêncio, Jorge Leitão, Yann Le Gal, Dominique Lorcy, Rafaela Silva, Mariana Velho, Dulce Belo, Manuel Almeida, Joana Guerreiro, Teresa Pinheiro, Fernanda M. Marques
The anticancer, antimicrobial and antiplasmodial activities of six gold(III) bis(dithiolene) complexes were studied. Complexes (1-6) showed relevant anticancer properties against A2780/A2780cisR ovarian cancer cells (IC50 values of 0.08-2 µM), also...
The content of this RSS Feed (c) The Royal Society of Chemistry




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[ASAP] Gold(I)-Catalyzed Highly Enantioselective [4 + 2]-Annulations of Cyclopentadienes with Nitrosoarenes via Nitroso-Povarov versus Oxidative Nitroso-Povarov Reactions

ACS Catalysis
DOI: 10.1021/acscatal.0c01293




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[ASAP] ß-Cyclodextrin–NHC–Gold(I) Complex (ß-ICyD)AuCl: A Chiral Nanoreactor for Enantioselective and Substrate-Selective Alkoxycyclization Reactions

ACS Catalysis
DOI: 10.1021/acscatal.0c00127




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The cold centre / Inka Parei

Hayden Library - PT2676.A665 K3513 2014




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Hermann Hesse über "Narziss und Goldmund": eine Dokumentation zur Entstehungs- und Wirkungsgeschichte / herausgegeben von Volker Michels

Hayden Library - PT2617.E85 Z48 2015




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Science Podcast - Monstrous stone monuments of old and a rundown of stories from our daily news site (3 Jan 2014)

Britain's prehistoric stone monuments; stories from our daily news site.




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The oldest piece of Mars on Earth and a news roundup (21 November 2014)

Eric Hand discusses the winding history of the Black Beauty meteorite--a 4.4 billion-year-old piece of Mars. Online news editor David Grimm brings stories on bacteria's role in the blood-brain barrier, the "ice-pocalypse", and why only 10 percent of galaxies may host complex life. Hosted by Sarah Crespi. [Img: © Joe McNally]




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Podcast: Combatting malnutrition with gut microbes, fighting art forgers with science, and killing cancer with gold

Online News Editor David Grimm shares stories on how our abilities shape our minds, killing cancer cells with gold nanoparticles, and catching art forgery with cat hair.   Laura Blanton joins host Sarah Crespi to discuss how nourishing our gut microbes may prevent malnutrition. Read the related research in Science.   [Image: D. S. Wagner et al., Biomaterials, 31 (2010)]   Authors: Sarah Crespi; David Grimm




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Podcast: Saving wolves that aren’t really wolves, bird-human partnership, and our oldest common ancestor

Stories on birds that guide people to honey, genes left over from the last universal common ancestor, and what the nose knows about antibiotics, with Devi Shastri.  The Endangered Species Act—a 1973 U.S. law designed to protect animals in the country from extinction—may need a fresh look. The focus on “species” is the problem. This has become especially clear when it comes to wolves—recent genetic information has led to government agencies moving to delist the grey wolf. Robert Wayne helps untangle the wolf family tree and talks us through how a better understanding of wolf genetics may trouble their protected status.  [Image: Claire N. Spottiswoode/Music: Jeffrey Cook]




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Podcast: 400-year-old sharks, busting a famous scientific hoax, and clinical trials in pets

News stories on using pets in clinical trials to test veterinarian drugs, debunking the Piltdown Man once and for all, and deciding just how smart crows can be, with David Grimm.   From the magazine It’s really difficult to figure out how old a free-living animal is. Maybe you can find growth rings in bone or other calcified body parts, but in sharks like the Greenland shark, no such hardened parts exist. Using two different radiocarbon dating approaches, Julius Neilsen and colleagues discovered that the giant Greenland shark may live as long as 400 years.   Read the research.   [Image: James Howard McGregor/Wikimedia Commons/Music: Jeffrey Cook]




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Podcast: An 80-million-year-old dinosaur protein, sending oxygen to the moon, and competitive forecasting

This week, we chat about how the Earth is sending oxygen to the moon, using a GPS data set to hunt for dark matter, and retrieving 80-million year old proteins from dinosaur bones, with Online News Editor David Grimm. And Philip Tetlock joins Alexa Billow to discuss improving our ability to make judgments about the future through forecasting competitions as part of a special section on prediction in this week’s issue of Science. Listen to previous podcasts. [Image: NASA; Music: Jeffrey Cook]




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How to weigh a star—with a little help from Einstein, toxic ‘selfish genes,’ and the world’s oldest Homo sapiens fossils

This week we have stories on what body cams reveal about interactions between black drivers and U.S. police officers, the world’s oldest Homo sapiens fossils, and how modern astronomers measured the mass of a star—thanks to an old tip from Einstein—with Online News Intern Ryan Cross. Sarah Crespi talks to Eyal Ben-David about a pair of selfish genes—one toxin and one antidote—that have been masquerading as essential developmental genes in a nematode worm. She asks how many more so-called “essential genes” are really just self-perpetuating freeloaders? Science Careers Editor Rachel Bernstein is also here to talk about stress and work-life balance for researchers and science students. Listen to previous podcasts. [Image: Chris Burns/Science; Music: Jeffrey Cook]




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Building conscious machines, tracing asteroid origins, and how the world’s oldest forests grew

This week we hear stories on sunlight pushing Mars’s flock of asteroids around, approximately 400-million-year-old trees that grew by splitting their guts, and why fighting poverty might also mean worsening climate change with Online News Editor David Grimm. Sarah Crespi talks with cognitive neuroscientist Stanislas Dehaene of the Collège de France in Paris about consciousness—what is it and can machines have it? For our monthly books segment, Jen Golbeck reviews astronaut Scott Kelly’s book Endurance: A Year in Space, A Lifetime of Discovery. Listen to previous podcasts. [Image: NASA/Goddard; Music: Jeffrey Cook]​




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Folding DNA into teddy bears and getting creative about gun violence research

This week, three papers came out describing new approaches to folding DNA into large complex shapes—20 times bigger than previous DNA sculptures. Staff Writer Bob Service talks with Sarah Crespi about building microscopic teddy bears, doughnuts, and more from genetic material, and using these techniques to push forward fields from materials science to drug delivery. Sarah also interviews Philip Cook of Duke University in Durham, North Carolina, about his Policy Forum on gun regulation research. It’s long been hard to collect data on gun violence in the United States, and Cook talks about how some researchers are getting funding and hard data. He also discusses some strong early results on open-carry laws and links between gun control and intimate partner homicide. Listen to previous podcasts. [Image: : K. WAGENBAUER ET AL., NATURE, VOL. 551, 2017; Music: Jeffrey Cook]




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Metaresearchers take on meta-analyses, and hoary old myths about science

Meta-analyses—structured analyses of many studies on the same topic—were once seen as objective and definitive projects that helped sort out conflicts amongst smaller studies. These days, thousands of meta-analyses are published every year—many either redundant or contrary to earlier metaworks. Host Sarah Crespi talks to freelance science journalist Jop de Vrieze about ongoing meta-analysis wars in which opposing research teams churn out conflicting metastudies around important public health questions such as links between violent video games and school shootings and the effects of antidepressants. They also talk about what clues to look for when trying to evaluate the quality of a meta-analysis. Sarah also talked with three other contributors to our “Research on Research” special issue. Pierre Azoulay of the Massachusetts Institute of Technology (MIT) in Cambridge, Ben Jones of Northwestern University in Evanston, Illinois, and MIT’s Heidi Williams discuss the evidence for some hoary old scientific home truths. See whether you can guess who originally made these claims and how right or wrong they were: Do scientists make great contributions after age 30? How important is it to stand on the shoulders of giants? Does the truth win, or do its opponents just eventually die out? Read the rest of the package on science under scrutiny here. This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts. About the Science Podcast [Image: Davide Bonazzi/@SalzmanArt; Show music: Jeffrey Cook; additional music: Nguyen Khoi Nguyen]




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How the appendix could hold the keys to Parkinson’s disease, and materials scientists mimic nature

For a long time, Parkinson’s disease was thought to be merely a disorder of the nervous system. But in the past decade researchers have started to look elsewhere in the body for clues to this debilitating disease—particularly in the gut. Host Meagan Cantwell talks with Viviane Labrie of the Van Andel Institute in Grand Rapids, Michigan, about new research suggesting people without their appendixes have a reduced risk of Parkinson’s. Labrie also describes the possible mechanism behind this connection. And host Sarah Crespi talks with Peter Fratzl of the Max Planck Institute of Colloids and Interfaces in Potsdam, Germany, about what materials scientists can learn from nature. The natural world might not produce innovations like carbon nanotubes, but evolution has forged innumerable materials from very limited resources—mostly sugars, proteins, and minerals. Fratzl discusses how plants make time-release seedpods that are triggered by nothing but fire and rain, the amazing suckerin protein that comprises squid teeth, and how cicadas make their transparent, self-cleaning wings from simple building blocks. Fratzl’s review is part of a special section in Science on composite materials. Read the whole package, including a review on using renewables like coconut fiber for building cars and incorporating carbon nanotubes and graphene into composites. This week’s episode was edited by Podigy. Download the transcript (PDF) Listen to previous podcasts. About the Science Podcast [Image: Roger Smith/Flickr; Music: Jeffrey Cook]




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The age-old quest for the color blue and why pollution is not killing the killifish

Humans have sought new materials to make elusive blue pigments for millennia—with mixed success. Today, scientists are tackling this blue-hued problem from many different angles. Host Sarah Crespi talks with contributing correspondent Kai Kupferschmidt about how scientists are looking to algae, bacteria, flowers—even minerals from deep under Earth’s crust—in the age-old quest for the rarest of pigments. Also this week, host Meagan Cantwell speaks with Andrew Whitehead, associate professor in the department of environmental toxicology at the University of California, Davis, about how the Atlantic killifish rescued its cousin, the gulf killifish, from extreme pollution. Whitehead talks about how a gene exchange occurred between these species that normally live thousands of kilometers apart, and whether this research could inform future conservation efforts. This week’s episode was edited by Podigy Download the transcript (PDF) Ads on this show: KiwiCo Listen to previous podcasts. About the Science Podcast




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From nose to toes—how coronavirus affects the body, and a quantum microscope that unlocks the magnetic secrets of very old rocks

Coronavirus affects far more than just the lungs, and doctors and researchers in the midst of the pandemic are trying to catalog—and understand—the virus’ impact on our bodies. Staff Writer Meredith Wadman joins host Sarah Crespi to discuss what we know about how COVID-19 kills. See all of our News coverage of the pandemic here, and all of our Research and Editorials here. Also this week, Staff Writer Paul Voosen talks with Sarah about quantum diamond microscopes. These new devices are able to detect minute traces of magnetism, giving insight into the earliest movements of Earth’s tectonic plates and even ancient paleomagnetic events in space. This week’s episode was produced with help from Podigy. Listen to previous podcasts. About the Science Podcast Download a transcript (PDF).




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English's pronoun problem is centuries old

Language works as a dynamic democracy, not as rule by experts.




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'Chintu<I>ji</I>'s scolding was always hilarious'

Juhi Chawla remembers her co-star Rishi Kapoor.




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In situ imaging of intracellular human telomerase RNA with molecular beacon-functionalized gold nanoparticles

Anal. Methods, 2020, Advance Article
DOI: 10.1039/D0AY00461H, Paper
Tao Xie, Ziyan Fan, Ruilong Zhang, Xiaohe Tian, Guangmei Han, Zhengjie Liu, Zhongping Zhang
We develop molecular beacon-functionalized gold nanoparticles for in situ human telomerase RNA imaging in live cells.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Broad band : the untold story of the women who made the Internet / Claire L. Evans

Evans, Claire Lisa, author




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Cyclic boronates as versatile scaffolds for KPC-2 β-lactamase inhibition

RSC Med. Chem., 2020, 11,491-496
DOI: 10.1039/C9MD00557A, Research Article
Catherine L. Tooke, Philip Hinchliffe, Alen Krajnc, Adrian J. Mulholland, Jürgen Brem, Christopher J. Schofield, James Spencer
Mono- (vaborbactam) and bi-cyclic (taniborbactam) boronate inhibitors bind KPC-2 similarly, but the latter is essentially irreversible.
The content of this RSS Feed (c) The Royal Society of Chemistry




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The Cambridge handbook of stakeholder theory / edited by Jeffrey S. Harrison (University of Richmond) [and three others]

Dewey Library - HD31.C326 2019




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Sustainable and Safe Dams Around the World /: Proceedings of the ICOLD 2019 Symposium, (ICOLD 2019), June 9-14, 2019, Ottawa, Canada = Publications du Symposium CIGB 2019, Juin 9-14, 2019, Ottawa, Canada un Monde de Barrages Durables et Sécuritaires

Online Resource




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Inductive melting and holding: fundamentals, plants and furnaces, process engineering / Erwin Dötsch

Online Resource




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The state, popular mobilisation and gold mining in Mongolia: shaping 'neoliberal' policies / Dulam Bumochir

Online Resource




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Frost action in soils: fundamentals and mitigation in a changing climate / prepared by the Frozen Ground Committee and the Transportation and Infrastructure Committee of the Cold Regions Engineering Division of the American Society of Civil Engineers ; ed

Online Resource




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Turning silicon into gold: the strategies, failures, and evolution of the tech industry / Griffin Kao, Jessica Hong, Michael Perusse, Weizhen Sheng

Online Resource




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Korea : a Cold War conflict 1950 - 1953 : a publication for secondary schools




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Western Australia looking west / [photographer:] Richard Woldendorp ; [commentaries by] Geoffrey Bolton ... [et al]

Woldendorp, Richard, 1927-




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A sarong for Clio : essays on the intellectual and cultural history of Thailand : inspired by Craig J. Reynolds / Maurizio Peleggi, editor




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One world divisible : a global history since 1945 / David Reynolds

Reynolds, David, 1952-




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The fall of tsarism : untold stories of the February 1917 Revolution / Semion Lyandres

Lyandres, Semion, 1959- author




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Golden destiny : the centenary history of Kalgoorlie-Boulder and the Eastern Goldfields of Western Australia / by Martyn and Audrey Webb

Webb, Martyn J. (Martyn Jack), 1925-2016




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14-year-old boy dies after police ‘thrash’ him

Four such videos of policemen beating up people surface online




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[ASAP] Capping Ligand Size-Dependent LSPR Property Based on DNA Nanostructure-Mediated Morphological Evolution of Gold Nanorods for Ultrasensitive Visualization of Target DNA

Analytical Chemistry
DOI: 10.1021/acs.analchem.0c00321