coronavirus

Coronavirus impact: Early funding of start-ups may hit a stumbling block

This comes as seed investments in India during the January-March quarter, which was hit by the lowest level in five quarters





coronavirus

The 2019 Novel Coronavirus Outbreak – Update From NIAID’s Anthony Fauci, MD

In February 2020 the nature of the 2019-nCoV outbreak is still slowly coming into focus but it appears to be acting more like bad pandemic influenza (efficient spread, overall lower mortality) than like SARS (less efficient spread, overall higher mortality). Anthony Fauci, MD, of the US National Institute of Allergy and Infectious Diseases (NIAID) discusses the latest developments with JAMA Editor in Chief Howard Bauchner.

Coronavirus Resource Center




coronavirus

Coronavirus in Italy—Report From the Front Lines

Physicians in Lombardy, Italy, have been overwhelmed by COVID-19 patients requiring critical care. Based on an existing ECMO center network they developed an ICU network to rapidly identify, triage, and manage patients infected with SARS-2-CoV. Maurizio Cecconi, MD, of Humanitas University in Milan discusses the region’s approach to the surge, including clinical and supply management, health care worker training and protection, and ventilation strategies, with JAMA Editor Howard Bauchner.

Read the article:

Critical Care Utilization for the COVID-19 Outbreak in Lombardy, Italy: Early Experience and Forecast During an Emergency Response




coronavirus

Coronavirus Testing – March 16 Q&A with the CDC’s Jay Butler, MD

Coronavirus testing will help countries manage coronavirus disease 2019 (COVID-19) but will raise questions about how to counsel patients about their test results. The CDC's Deputy Director for Infectious Diseases Jay C. Butler, MD, talks with JAMA Editor Howard Bauchner about what to advise healthy patients with positive PCR results, sick patients with negative test results, exposed health care workers, and more.




coronavirus

Coronavirus Disease 2019 (COVID-19) Mitigation: Preparing Hospitals and Health Systems

The strategy for managing the COVID-19 pandemic has shifted from containment to mitigation. What does that mean for US hospitals and health systems? Kaiser Permanente Executive Vice President Stephen M. Parodi, MD, discusses telemedicine, protecting health care workers, equipment allocation planning, and more.




coronavirus

Coronavirus in New York - Report From the Front Lines

The ARDS in COVID-19 patients appears more responsive to PEEP and prone ventilation, but seems to require prolonged ventilation and may be associated with myocardial injury. Michelle N. Gong, MD, MS, Chief of Critical Care Medicine at Montefiore Medical Center in the Bronx, discusses her department's experience managing critically ill coronavirus patients, procuring diagnostic tests and personal protective equipment (PPE) for her staff, and more.




coronavirus

Coronavirus (COVID-19) Update: Vaccines and Immunity

As COVID-19 spreads globally, populations who survive their illness will become immune. Mayo Vaccine Research Group Director Gregory Poland, MD, discusses antibody responses, duration of immunity, vaccine safety, and the prospects for using convalescent serum to passively immunize people unexposed to SARS-CoV-2.




coronavirus

Coronavirus (COVID-19) Update: Fairly Rationing ICU Care

Hospitals need ways to make rational, fair decisions about who gets ICU beds and ventilators if COVID-19 patients overwhelm capacity. Douglas B. White, MD, MAS, Director of the Program on Ethics and Decision Making in Critical Illness at the University of Pittsburgh, discusses a framework for those decisions and a guideline he helped develop for allocation of scarce resources in public health emergencies.




coronavirus

Coronavirus (COVID-19) Update: The Near Future

How does the current pandemic compare to historical infectious outbreaks and what can we expect in summer and fall of 2020? Nicholas Christakis, MD, PhD, MPH, director of the Human Nature Lab, Co-director of the Institute of Network Science, and Sterling Professor of Social and Natural Science at Yale University, discusses the epidemiology of COVID-19.




coronavirus

Coronavirus (COVID-19) Update: Critical Care Management

Noninvasive ventilation (NIV), working with dying patients’ families, use of experimental therapies, and more. JAMA Associate Editor Derek Angus, MD, MPH, Distinguished Professor and Chair of Critical Care Medicine at the University of Pittsburgh, provides a COVID-19 ICU management update.

Watch the recording of this livestream




coronavirus

Coronavirus Disease 2019 (COVID-19) Update: Epidemics in History

Infectious epidemics have always driven change and triggered discrimination in human societies. Frank Snowden, DPhil, Professor Emeritus of History and History of Medicine at Yale University and author of Epidemics and Society: From the Black Death to the Present (Yale University Press, 2019), puts the COVID-19 pandemic in historical context.




coronavirus

Coronavirus (COVID-19) Update: Clinical Review

Questions about testing, chloroquine toxicity, duration of immunity and reinfection, and what to expect next are gripping the US as the novel coronavirus spreads. JAMA Associate Editor Preeti Malani, MD, professor of medicine and Chief Health Officer at the University of Michigan, discusses recent developments in a live conversation with JAMA Editor in Chief Howard Bauchner. Recorded on April 6, 2020.




coronavirus

Coronavirus Q&A: Former Utah Governor and HHS Secretary Mike Leavitt

US states are taking the lead in managing the COVID-19 pandemic. What can state governors expect from the federal government and from the US Department of Health and Human Services? Governor Mike Leavitt from Leavitt Partners joins JAMA Editor Howard Bauchner, MD, in this live Q&A. Recorded April 8, 2020.




coronavirus

New York City Coronavirus (COVID-19) Update

New York City coronavirus update from Mitchell Katz, MD, President and CEO of NYC Health + Hospitals, the largest municipal public health system in the United States. Recorded April 13, 2020.




coronavirus

Coronavirus and Health Policy

JAMA Health Forum editors John Ayanian, MD, MPP, and Melinda Buntin, PhD, discuss changes in US health care and health policy driven by the coronavirus pandemic. Recorded April 16, 2020.




coronavirus

Coronavirus Q&A: Update From the CDC

Anne Schuchat, MD, Principal Deputy Director of the Centers for Disease Control and Prevention (CDC), discusses evolution of CDC guidance and latest developments in the COVID-19 pandemic. Recorded Friday May 1, 2020.




coronavirus

Understanding Observational Treatment Comparisons in the Setting of Coronavirus Disease 2019 (COVID-19)

With the emergence of coronavirus disease 2019 (COVID-19) as a global pandemic, individuals with preexisting chronic health conditions such as hypertension, diabetes, and cardiovascular disease have been identified as particularly vulnerable. These patients are also more likely than the general population to be taking angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs). As the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus that causes COVID-19 gains entry into cells via binding to the angiotensin-converting enzyme 2 (ACE2) receptor, concerns have been raised that these therapies might facilitate the transmission of the virus or affect outcomes adversely. Given that ACEI and ARB therapies are known to provide benefit for the underlying conditions treated, stopping ACEI/ARB therapy carries risks. Moreover, local inactivation of the renin-angiotensin-aldosterone system may have protective effects against the development and progression of acute lung failure. In the absence of clinical evidence of benefit or risk of ACEIs/ARBs, current societal statements recommend against discontinuing these drugs other than for standard clinical indications. Robust clinical data are needed to clarify the effect of ACEIs/ARBs on SARS-CoV-2 infection.




coronavirus

Amul to Dettol: Brands go viral with safety messages about coronavirus

From advisories and warnings to smart witticisms, brands across categories are reaching out to consumers over the shadow of Covid-19




coronavirus

Coronavirus: Health scare forces work from home, but is India Inc ready?

India Inc has embraced remote working because of a health scare. But there are important lessons on enabling infrastructure, managing remote teams and ensuring productivity...




coronavirus

Soap success: Medimix reports business surge as coronavirus spreads

The medicinal soap brand is seeing a sharp spurt in demand across the country




coronavirus

As coronavirus cases spike, social media battles the epidemic of fakes

Google, Twitter, TikTok, Facebook team up with global health agencies and governments to put up the guardrails on the fake trail




coronavirus

AIIB extends $500 mn loan to India to deal with coronavirus crisis

The bank's board of directors has approved a loan to India to strengthen the preparedness of the country's national health system




coronavirus

Global patterns in coronavirus diversity




coronavirus

Discovery of a rich gene pool of bat SARS-related coronaviruses provides new insights into the origin of SARS coronavirus




coronavirus

Ecology, evolution and classification of bat coronaviruses in the aftermath of SARS




coronavirus

Bats are natural reservoirs of SARS-like coronaviruses




coronavirus

Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats




coronavirus

Prevalence and genetic diversity of coronaviruses in bats from China




coronavirus

Identification of diverse alphacoronaviruses and genomic characterization of a novel Severe Acute Respiratory Syndrome-Like coronavirus from bats in China




coronavirus

Genomic characterization of Severe Acute Respiratory Syndrome-related coronavirus in European bats and classification of coronaviruses based on partial RNA-dependent RNA polymerase gene sequences




coronavirus

Detection of novel SARS-like and other coronaviruses in bats from Kenya




coronavirus

Isolation and characterization of a novel bat coronavirus closely related to the direct progenitor of Severe Acute Respiratory Syndrome coronavirus




coronavirus

Full-length genome sequences of two SARS-like coronaviruses in horseshoe bats and genetic variation analysis




coronavirus

Bat Severe Acute Respiratory Syndrome-like coronavirus WIV1 encodes an extra accessory protein, ORFX, involved in modulation of the host immune response




coronavirus

Ecoepidemiology and Complete Genome Comparison of different strains of Severe Acute Respiratory Syndrome-Related Rhinolophus Bat Coronavirus in China reveal bats as a reservoir for acute, self-limiting infection that allows recombination events




coronavirus

Novel SARS-like betacoronaviruses in bats, China, 2011




coronavirus

ORF8-related genetic evidence for Chinese horseshoe bats as the source of human Severe Acute Respiratory Syndrome coronavirus




coronavirus

Longitudinal surveillance of SARS-like coronaviruses in bats by quantitative real-time PCR




coronavirus

A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence




coronavirus

Difference in receptor usage between Severe Acute Respiratory Syndrome (SARS) coronavirus and SARS-like coronavirus of bat origin




coronavirus

Bat severe acute respiratory syndrome-like coronavirus ORF3b homologues display different interferon antagonist activities




coronavirus

The evolving design of the Coronavirus

The podium placard has been the silent messenger of the daily Coronavirus briefings.




coronavirus

Amid coronavirus lockdown, steel demand pick-up off to a slow start

Construction activities have resumed, albeit in a staggered manner; in some pockets there is demand for yellow goods as well




coronavirus

Uber loses $2.9 bn in coronavirus crisis, drops bike and scooter business

Demand for the Eats business grew 89 per cent in April, excluding India, and we've seen an enormous acceleration in demand since mid-March, Khosrowshahi said




coronavirus

The wash brigade: Inculcating a simple habit to fight coronavirus pandemic

As the world population feverishly washes hands, an initiative by a small NGO in Uttar Pradesh seems prescient




coronavirus

In this coronavirus lockdown, India feels like the calm before the storm

Strong social networks got India through the calamity of demonetisation. By not giving migrant workers enough time to get home, the govt has likely deprived them of this




coronavirus

Finding mask a daunting task amid coronavirus. Should you make your own?

While we don't have a lot of research on the effectiveness of homemade masks in preventing the spread of infection, scientists who study airborne diseases can offer some guidance.




coronavirus

LIC in the time of coronavirus: A question mark now on the mega IPO

The listing of LIC is being thought when it is still a pre-dominant player in the sector. This is just like in the case of the State Bank of India in 1993




coronavirus

Three ways to combat coronavirus

Strengthening primary and community health care, combined with vastly expanded testing, will be key to overcoming the pandemic that threatens to rage through the country