en Fertility awareness based methods for pregnancy prevention By feeds.bmj.com Published On :: Sat, 13 Jul 2019 17:38:01 +0000 Fertility awareness based methods of contraception are increasingly being used for pregnancy prevention. In the US, the proportion of contraceptive users who choose such methods has grown from 1% in 2008 to approximately 3% in 2014. Relative to other methods of pregnancy prevention, however, substantial misinformation exists around fertility... Full Article
en Fighting bad science in Austria By feeds.bmj.com Published On :: Wed, 17 Jul 2019 16:29:32 +0000 Cochrane Austria have been asking the public what they'd like to know about health. Not whether the latest drug is more efficacious, but whether glacier stone power cures hangovers. Gerald Gartlehner, director of the Cochrane Austria Centre joins us to explain what they do, and how their evidence has been received. Read more about the project... Full Article
en Patient's rights in research - moving beyond participation By feeds.bmj.com Published On :: Thu, 25 Jul 2019 14:54:57 +0000 At EBM live recently, we ran a workshop with researchers, patients and clinicians to talk about patient rights in research - should patients be setting the full research agenda? Should they be full participants and authors? Helen Macdonald, BMJ’s UK research editor and co-host of our talk evidence podcast sat down to Paul Wicks, researcher and... Full Article
en Burnout - Don't try to make the canary in the coal mine more resilient By feeds.bmj.com Published On :: Thu, 08 Aug 2019 16:59:04 +0000 Burnout is a problem in healthcare - it’s a problem for individuals, those who experience it and decide to leave a career they formerly loved, but it’s also a problem for our healthcare system. Burnout is associated with an increase in medical errors, and poor quality of care. Fundamentally it’s a patient safety issue. But, unlike other patient... Full Article
en Gottfried Hirnschall is optimistic about ending the HIV epidemic By feeds.bmj.com Published On :: Thu, 15 Aug 2019 16:45:11 +0000 In 2001, Gottfried Hirnschall joined the WHO to work on the global response to HIV/AIDs, 18 years later he just retired as the director of WHO’s department for HIV and Hepatitis. The intervening period, almost half the time we’ve been aware of the disease the fight against the infection has been characterised by scientific breakthroughs, and... Full Article
en Talk Evidence - Tramadol, medical harm, and alexa By feeds.bmj.com Published On :: Wed, 21 Aug 2019 10:49:28 +0000 Welcome back to Talk Evidence - where Helen Macdonald and Carl Heneghan take you through what's happening in the world of Evidence. This month we'll be discussing tramadol being prescripted postoperatively, and a new EBM verdict says that should change(1.36). How much preventable harm does healthcare causes (11.20. A canadian project to help... Full Article
en The government is lacking detail over Brexit planning By feeds.bmj.com Published On :: Wed, 04 Sep 2019 17:43:31 +0000 Brexit. Who knows what’s going to happen in the next few weeks, months, years - the uncertainty is high. In the face of that, you’d hope that the government was doing all it could to plan for any eventuality - let alone for a massive, country altering one like suddenly crashing out without a deal - but Martin McKee, professor of public health at... Full Article
en Extending the UK's sugar tax to snacks By feeds.bmj.com Published On :: Fri, 06 Sep 2019 11:54:58 +0000 In the UK, for just over a year, we've been paying the "Soft Drinks Industry Levy" - a tax on sugary beverages intended to reduce our consumption of free sugars. That was based on taxes that had happened in other countries, however, in the UK high sugar snacks, such as confectionery, cakes, and biscuits make a greater contribution to intakes of... Full Article
en Talk Evidence - Recurrent VTE, CRP testing for COPD, CMO report, and a consultation By feeds.bmj.com Published On :: Mon, 23 Sep 2019 10:21:58 +0000 Helen talks about new research on prevention of recurrent VTE - and Carl things the evidence goes further, and we can extend prophylaxis for a year. 13.00 - CRP testing for antibiotic prescription in COPD exacerbations, should we start doing it in primary care settings - and what will that mean. We also hear from Chris Butler, one of the... Full Article
en Talk Evidence - eating less, drinking less, drug approval data By feeds.bmj.com Published On :: Fri, 04 Oct 2019 16:41:57 +0000 Talk Evidence is back, with your monthly take on the world of EBM with Duncan Jarvies and GPs Carl Heneghan (also director for the Centre of Evidence Based Medicine at the University of Oxford) and Helen Macdonald (also The BMJ's UK research Editor). This month Carl talks about evidence that restricting your diet might improve health at a... Full Article
en How Blockchain could improve clinical trial transparency By feeds.bmj.com Published On :: Sat, 12 Oct 2019 13:06:50 +0000 Blockchain is the digital technology that underpins cryptocurrencies such as bitcoin, and has been proposed as the digital panacea of our times. But Leeza Osipenko, from the London School of Economics, has thought about how it could actually be used in clinical trials, and what else would need to change in our regulatory environment to make that... Full Article
en Ancestry DNA tests can over or under estimate genetic disease risk By feeds.bmj.com Published On :: Thu, 17 Oct 2019 14:36:18 +0000 Direct-to-consumer genetic tests are sold online and in shops as a way to “find out what your DNA says". They insights into ancestry or disease risks; others claim to provide information on personality, athletic ability, and child talent. However, interpretation of genetic data is complex and context dependent, and DTC genetic tests may produce... Full Article
en Statins for primary prevention - How good is the evidence By feeds.bmj.com Published On :: Mon, 21 Oct 2019 10:12:15 +0000 Statins are now the most commonly used drug in the UK and one of the most commonly used medicines in the world, but debate remains about their use for primary prevention for people without cardiovascular disease. Paula Byrne from the National University of Ireland Galway, joins us to talk about the evidence of benefit for low risk individuals,... Full Article
en Talk Evidence - aggravating acronyms, a time to prescribe, and screening (again) By feeds.bmj.com Published On :: Mon, 11 Nov 2019 11:51:44 +0000 Talk Evidence is back, with your monthly take on the world of EBM with Duncan Jarvies and GPs Carl Heneghan (also director for the Centre of Evidence Based Medicine at the University of Oxford) and Helen Macdonald (also The BMJ's UK research Editor). This month Helen talks about the messy business of colon cancer screening - which modality is... Full Article
en Behind the campaign promises - GP numbers, and appointment slots By feeds.bmj.com Published On :: Fri, 15 Nov 2019 16:59:59 +0000 A UK general election has been called - polling day is on the 12th of December, and from now until then we’re going to be bringing you a weekly election-themed podcast. We want to help you make sense of the promises and pledges, claims and counter-claims, that are being made around healthcare and the NHS out on the campaign trail. This week has... Full Article
en Behind the campaign promises - Health and social care spending By feeds.bmj.com Published On :: Fri, 22 Nov 2019 16:21:30 +0000 A UK general election has been called - polling day is on the 12th of December, and from now until then we’re going to be bringing you a weekly election-themed podcast. We want to help you make sense of the promises and pledges, claims and counter-claims, that are being made around healthcare and the NHS out on the campaign trail. This week... Full Article
en Behind the campaign promises - Doctors in parliament By feeds.bmj.com Published On :: Mon, 09 Dec 2019 18:52:26 +0000 The UK general election is happening this week, and you’ve probably made your mind up which MP you’re voting for already - and maybe the NHS has influenced that decision. This year has seen an increase in the number of doctors running for parliament, and in this podcast we find out what motivates doctors to step away from clinical practice, and... Full Article
en Talk Evidence - Talking about harms By feeds.bmj.com Published On :: Fri, 13 Dec 2019 18:18:10 +0000 In this special edition of talk evidence, Helen Macdonald and Carl Henneghan talk about creating an evidence base from harms. We hear from a member of the pubic who experienced harm from a drug, and now advises the FDA. A former regulator who explains why reporting harms is so important. And finally, an investigative journalist who explains what... Full Article
en Talk Evidence - digital clubbing, osteoarthritis & sustainable EBM By feeds.bmj.com Published On :: Mon, 16 Dec 2019 19:36:54 +0000 We’re back for the December Talk Evidence, and this month we’re being very digital Firstly,(1.20) Helen tells us about arthritic fingers - should we be using prednisolone for treatment when people have painful osteoarthritis of the hand Then (13.30) Carl gets us all to check our fingers for clubbing, and we find out how useful it is as a test... Full Article
en Talking up your research - Sex makes a difference By feeds.bmj.com Published On :: Fri, 20 Dec 2019 15:50:09 +0000 As editors, we feel like we’re spending a lot of time taking the superlatives out from articles - amazing, novel, important… But new research on BMJ.com suggests that we might not be doing that great a job, and that for some reason, papers authored by men tend to have more of them - because men put more in, or maybe a bias against woman writing in... Full Article
en Talk Xmas Evidence By feeds.bmj.com Published On :: Tue, 31 Dec 2019 14:52:53 +0000 Welcome to the festive talk evidence, giving you a little EBM to take you into the new year. As always Duncan Jarvies is joined by Helen Macdonald (resting GP and editor at The BMJ) and Carl Heneghan (active GP, director of Oxford University’s CEBM and editor of BMJ Evidence) This month: (2.00) Helen look back at a Christmas article, which... Full Article
en Surviving childhood cancer treatment By feeds.bmj.com Published On :: Tue, 21 Jan 2020 13:21:18 +0000 In a British cohort, 30% of patients who had survived childhood cancer had died within 45 years of diagnosis; only 6% were expected to have died. 51% had developed a new primary cancer, but a 26% died of cardiovascular disease - thought to be caused by their treatment. Consequently, efforts to reduce long term mortality have focused on reducing... Full Article
en Talk Evidence - Sepsis, talc and blindsided by blinding By feeds.bmj.com Published On :: Wed, 22 Jan 2020 17:40:40 +0000 Welcome to the festive talk evidence, giving you a little EBM to take you into the new year. As always Duncan Jarvies is joined by Helen Macdonald (resting GP and editor at The BMJ) and Carl Heneghan (active GP, director of Oxford University’s CEBM and editor of BMJ Evidence)* This month: (1.20) Carl tells us about new research on treating... Full Article
en Prevalence and treatment of precocious puberty By feeds.bmj.com Published On :: Tue, 28 Jan 2020 17:19:40 +0000 Precocious puberty, that is puberty that starts before age 8 in girls and 9 in boys seems to be on the rise, but whether that’s because of an increase in incidence, or greater attention is unknown - what we do know that precocious puberty in girls is commonly idiopathic, while in boys is a red flag for pathology. But either way ther first point of... Full Article
en QI and improvement are not synonyms By feeds.bmj.com Published On :: Fri, 31 Jan 2020 18:17:26 +0000 In October 2019, Mary Dixon-Woods, director of the THIS Institute, dedicated to healthcare improvement. In that she explained how she believed healthcare improvement could be improved. The essay took the position that "Quality Improvement" isn't necessarily the best way to improve healthcare, and that more rigour needs to be brought to the field.... Full Article
en Writing a good outpatient letter means addressing it to the patient By feeds.bmj.com Published On :: Fri, 07 Feb 2020 11:31:30 +0000 In many countries (including the UK and Australia) it is still common practice for hospital doctors to write letters to patients’ general practitioners (GPs) following outpatient consultations, and for patients to receive copies of these letters. However, Hugh Rayner, consultant nephrologist, and Peter Rees, former Chair of the Academy of... Full Article
en David Williams - everyday discrimination is an independent predictor of mortality By feeds.bmj.com Published On :: Thu, 13 Feb 2020 12:44:12 +0000 There comes a tipping point in all campaigns when the evidence is overwhelming and the only way to proceed is with action. According to David Williams, it’s time to tackle the disproportionate effects of race on patients in the UK. David Williams, from Harvard University, developed the Everyday Discrimination Scale that, in 1997, launched a new... Full Article
en Talk Evidence - Building an evidence base for covid-19 By feeds.bmj.com Published On :: Mon, 17 Feb 2020 15:22:17 +0000 We're taking a break from the usual Talk Evidence to focus on the new corona virus that has emerged in China. With a brand new disease, we have to build our evidence base from scratch - basic virology, epidemiology, pathogenicity, transmissibility, and ultimately treatment are all unknowns. In this episode of Talk Evidence, we're trying to get... Full Article
en Why we are failing patients with multimorbidity By feeds.bmj.com Published On :: Thu, 05 Mar 2020 14:54:02 +0000 We know that the number of people living with multiple health conditions is rising year on year, and yet training, guidelines, organisations and physical spaces in healthcare still largely focus on single diseases or organ systems. The means that patients in the NHS are often treated as if their conditions exist in isolation, and that their care... Full Article
en Cycling - Does the health benefit outweigh the accident risk (in the UK) By feeds.bmj.com Published On :: Thu, 12 Mar 2020 16:22:11 +0000 We all know we should be doing more exercise, and one way to do that is by active commuting - journeying to work on foot or by bike. One thing preventing people from taking up cycling is the fear of being involved in road traffic accidents, and that the risk isn't worth the benefit of the extra exercise. It’s even more confusing when air... Full Article
en For a greener NHS - a call for evidence By feeds.bmj.com Published On :: Sat, 14 Mar 2020 12:46:26 +0000 The NHS is a world leader in sustainable healthcare - and it's the staff who have have been leading the charge. The For A Greener NHS campaign is asking everyone who has made a change to the way they work, to submit evidence and help shape the whole organisation's response to the climate emergency. In this podcast, Isobel Braithwaite, public... Full Article
en Talk Evidence - testing under the microscope and opioid prescription By feeds.bmj.com Published On :: Fri, 20 Mar 2020 20:08:10 +0000 This edition of talk evidence was recorded before the big increase in covid-19 infections in the UK, and then delayed by some self isolation. We'll be back with more evidence on the pandemic very soon. As always Duncan Jarvies is joined by Helen Macdonald (resting GP and editor at The BMJ) and Carl Heneghan (active GP, director of Oxford... Full Article
en Talk Evidence Covid-19 update - Confused symptoms, fatality rate uncertainty, Iceland's testing By feeds.bmj.com Published On :: Fri, 27 Mar 2020 16:14:17 +0000 For the next few months Talk Evidence is going to focus on the new corona virus pandemic. There is an enormous amount of uncertainty about the disease, what the symptoms are, fatality rate, treatment options, things we shouldn't be doing. We're going to try to get away from the headlines and talk about what we need to know - to hopefully give... Full Article
en Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing By feeds.bmj.com Published On :: Thu, 09 Apr 2020 09:53:16 +0000 For the next few months Talk Evidence is going to focus on the new corona virus pandemic. There is an enormous amount of uncertainty about the disease, what the symptoms are, fatality rate, treatment options, things we shouldn't be doing. We're going to try to get away from the headlines and talk about what we need to know - to hopefully give... Full Article
en Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss By feeds.bmj.com Published On :: Mon, 13 Apr 2020 20:39:17 +0000 For the next few months Talk Evidence is going to focus on the new corona virus pandemic. There is an enormous amount of uncertainty about the disease, what the symptoms are, fatality rate, treatment options, things we shouldn't be doing. We're going to try to get away from the headlines and talk about what we need to know - to hopefully give... Full Article
en Talk Evidence - Remdesivir, care homes, and death data By feeds.bmj.com Published On :: Fri, 17 Apr 2020 15:00:49 +0000 For the next few months Talk Evidence is going to focus on the new corona virus pandemic. There is an enormous amount of uncertainty about the disease, what the symptoms are, fatality rate, treatment options, things we shouldn't be doing. We're going to try to get away from the headlines and talk about what we need to know - to hopefully give... Full Article
en Teleconsulting with Trish Greenhalgh and Fiona Stevenson By feeds.bmj.com Published On :: Wed, 22 Apr 2020 17:41:46 +0000 A new podcast from The BMJ, to help GP's feel more connected, heard, and supported. Subscribe on; Apple podcasts - https://bit.ly/applepodsDBI Spotify - https://bit.ly/spotifyDBI Google podcasts - https://bit.ly/googlepodsDBI In our first episode, we discuss the highs and lows of video consultations, and how coronavirus has altered the landscape... Full Article
en Talk Evidence - covid ethics, waste and a minimum RCT size By feeds.bmj.com Published On :: Fri, 24 Apr 2020 16:19:18 +0000 For the next few months Talk Evidence is going to focus on the new corona virus pandemic. There is an enormous amount of uncertainty about the disease, what the symptoms are, fatality rate, treatment options, things we shouldn't be doing. We're going to try to get away from the headlines and talk about what we need to know - to hopefully give... Full Article
en Talk Evidence covid-19 update - lack of testing transparency, how to give good debate By feeds.bmj.com Published On :: Mon, 04 May 2020 16:25:18 +0000 For the next few months Talk Evidence is going to focus on the new corona virus pandemic. There is an enormous amount of uncertainty about the disease, what the symptoms are, fatality rate, treatment options, things we shouldn't be doing. We're going to try to get away from the headlines and talk about what we need to know - to hopefully give you... Full Article
en Frontline stories - caring for non-covid patients By feeds.bmj.com Published On :: Tue, 05 May 2020 19:32:52 +0000 As the pandemic plays out - hospitals are reconfigured to increase critical care capacity, outpatient clinics become virtual, and elective procedures delayed. How are these affecting care for those who are in hospital but don't have covid-19? In this podcast, Matt Morgan,honorary senior research fellow at Cardiff University, consultant in... Full Article
en Talk evidence covid-19 update: natural history of covid, include patients in guidelines By feeds.bmj.com Published On :: Sat, 09 May 2020 09:13:00 +0000 For the next few months Talk Evidence is going to focus on the new corona virus pandemic. There is an enormous amount of uncertainty about the disease, what the symptoms are, fatality rate, treatment options, things we shouldn't be doing. We're going to try to get away from the headlines and talk about what we need to know - to hopefully give you... Full Article
en Glucose-Induced Reactive Oxygen Species Cause Apoptosis of Podocytes and Podocyte Depletion at the Onset of Diabetic Nephropathy By diabetes.diabetesjournals.org Published On :: 2006-01-01 Katalin SusztakJan 1, 2006; 55:225-233Complications Full Article
en C-Reactive Protein Is an Independent Predictor of Risk for the Development of Diabetes in the West of Scotland Coronary Prevention Study By diabetes.diabetesjournals.org Published On :: 2002-05-01 Dilys J. FreemanMay 1, 2002; 51:1596-1600Complications Full Article
en Morbidity and Mortality in Diabetics In the Framingham Population: Sixteen Year Follow-up Study By diabetes.diabetesjournals.org Published On :: 1974-02-01 Mariano J GarciaFeb 1, 1974; 23:105-111Original Contribution Full Article
en Moving GLUT4: The Biogenesis and Trafficking of GLUT4 Storage Vesicles By diabetes.diabetesjournals.org Published On :: 1997-11-01 Shane ReaNov 1, 1997; 46:1667-1677Perspectives in Diabetes Full Article
en High Incidence of Metabolically Active Brown Adipose Tissue in Healthy Adult Humans: Effects of Cold Exposure and Adiposity By diabetes.diabetesjournals.org Published On :: 2009-07-01 Masayuki SaitoJul 1, 2009; 58:1526-1531Metabolism Full Article
en Endothelial Progenitor Cell Dysfunction: A Novel Concept in the Pathogenesis of Vascular Complications of Type 1 Diabetes By diabetes.diabetesjournals.org Published On :: 2004-01-01 Cindy J.M. LoomansJan 1, 2004; 53:195-199Complications Full Article
en Thiazolidinediones in the Treatment of Insulin Resistance and Type II Diabetes By diabetes.diabetesjournals.org Published On :: 1996-12-01 Alan R SaltielDec 1, 1996; 45:1661-1669Perspectives in Diabetes Full Article
en Relation Between Antioxidant Enzyme Gene Expression and Antioxidative Defense Status of Insulin-Producing Cells By diabetes.diabetesjournals.org Published On :: 1997-11-01 Markus TiedgeNov 1, 1997; 46:1733-1742Original Article Full Article
en A Lesson in Metabolic Regulation Inspired by the Glucokinase Glucose Sensor Paradigm By diabetes.diabetesjournals.org Published On :: 1996-02-01 Franz M MatschinskyFeb 1, 1996; 45:223-241Banting Lecture 1995 Full Article