A casting core resulting from alkaline earth metal oxide particles having an average particle size of 0.8-4 mm being dispersed in a water-soluble alkali metal salt matrix. The casting core can be efficiently produced using a method of dispersing alkaline earth metal hydroxide particles having favorable disintegration properties and a particle size in the range of 1-5 mm in a molten water-soluble alkali metal salt, converting to alkaline earth metal oxide particles by means of dehydration, and casting in a mold, cooling, and hardening.

A method of producing a trailing arm of a torsion beam axle in which an integrated drive unit of a wheel-adjacent electric drive has an electric machine and a transmission. By using the method, the trailing arm is produced in the form of a casting with a box profile. The contours for producing the area that accommodates the transmission, the connection point to the vehicle body, the bore that receives the cross-member which connects the two trailing arms to one another, the U-profile of the trailing arm, the box profile and the area that accommodates the electric machine, are modeled by cores such that the contours for producing the connection point of the trailing arm to the vehicle body, the bore that receives the cross-member and the U-profile of the trailing arm are modeled by one core.

Various embodiments provide systems and methods for casting amorphous alloys. Exemplary casting system may include an insertable and rotatable vessel configured in a non-movable induction heating structure for melting amorphous alloys to form molten materials in the vessel. While the molten materials remain heated, the vessel may be rotated to pour the molten materials into a casting device for casting them into articles.

An inline bitumen froth steam heater system including steam injection and static mixing devices is provided. The system heats and de-aerates input bitumen froth without creating downstream processing problems with the bitumen froth such as emulsification or live steam entrainment. The system is a multistage unit that injects and thoroughly mixes steam with bitumen resulting in output bitumen material having temperature of about 190° F. The system conditions a superheated steam supply to obtain saturated steam at about 300° F. The saturated steam is contacted with bitumen froth flow and mixed in a static mixer stage. The static mixers provide surface area and rotating action that allows the injected steam to condense and transfer its heat to the bitumen froth. The mixing action and increase in temperature of the bitumen froth results in reduction in bitumen viscosity and allows the release of entrapped air from the bitumen froth.

A device for processing a hydrocarbon resource may include a hydrocarbon processing container configured to receive the hydrocarbon resource therein and having a pair of opposing ends with an enlarged width medial portion therebetween. The device may also a spirally wound electrical conductor surrounding the hydrocarbon processing container, and a radio frequency (RF) circuit coupled to the spirally wound electrical conductor and configured to supply RF power to the hydrocarbon resource while tracking a load resonance of the RF circuit. The RF circuit may be configured to generate magnetic fields within the hydrocarbon processing container parallel with an axis thereof.

A device for processing a hydrocarbon resource may include a hydrocarbon processing container configured to receive the hydrocarbon resource therein and having a pair of opposing ends with an enlarged width medial portion therebetween. The device may also include a radio frequency (RF) source, and a first spirally wound electrical conductor surrounding the hydrocarbon processing container and coupled to the RF source. The device may further include a second spirally wound electrical conductor carried within the hydrocarbon processing container. The first spirally wound electrical conductor may be configured to generate magnetic fields with the hydrocarbon processing container that are parallel with an axis thereof.

A device for processing a hydrocarbon resource may include a hydrocarbon processing container configured to receive the hydrocarbon resource therein and having a pair of opposing ends with an enlarged width medial portion therebetween. The device may also include a radio frequency (RF) source, and a spirally wound electrical conductor surrounding the hydrocarbon processing container and coupled to the RF source. The spirally wound electrical conductor may be configured to generate magnetic fields within the hydrocarbon processing container that are parallel with an axis thereof.

Two-stage hydroprocessing uses a common dividing wall fractionator. Hydroprocessed effluents from both stages of hydroprocessing are fed to opposite sides of the dividing wall.

The present invention provides a method and an apparatus for recovery of spent lubricating oil. The evaporation of hydrocarbon fractions from spent lubricating oil is carried out in three steps. The first step is at approximately 150-1030 mbar and between 70-240° C. in which is greater than 99% water, greater than 99% of ethylene glycol and greater than 50% of hydrocarbon molecules with normal boiling point up to 310° C. are evaporated from spent oil. The second step is operated at 6-30 mbar and 200-2900 C in which predominantly gasoil and light vacuum gasoil fractions are evaporated. The third step is operated at 250-320° C. and 0.5-15 mbar in which mainly heavy vacuum gasoil (boiling range of 425 to 570° C. on ASTM D-1160 test) is evaporated from spent oil.

Provided is a glove which has good adhesiveness to a rubber or resin coating material and excellent durability and further fits a hand well enabling good work efficiency. The glove is knitted from a covered yarn obtained by winding a sheath yarn around a core yarn and at least a part of the surface thereof is coated with a rubber or resin coating material, wherein the sheath yarn is a crimped yarn made of a high strength fiber having, as a property of a raw yarn, a tensile strength of 1.75 N/tex or more as measured according to JIS L 1013 8.5, and the crimped yarn simultaneously satisfies the following (1) to (3): (1) a degree of bulkiness of 40 cm3/g or more as measured according to JIS L 1013 8.16 A method after hot water treatment at 90° C. for 20 minutes, (2) a bulk compression modulus of 80% or more as measured according to the same method, and (3) a shrinkage/elongation ratio of 20% or more as measured according to JIS L 1013 8.11 A method.

A rotary sinker enabling stitch formation by a knitting machine using a rotor for forming a stitch, a knitting machine including the rotary sinker, and a stitch forming method are provided. The ring sinkers as rotating bodies are capable of rotating about a rotation axis independently of each other. The rotation times of the ring sinkers are set to be different from each other. Thus, the rotation times are adjusted to be different between the ring sinker that holds an old loop and the ring sinker that holds a new loop. Adjustment of the rotation times prevents application of a large tension to the knitting yarn made of low stretch fiber, and a stitch can be formed even with a knitting yarn made of non-stretch or low-stretch fiber.

A knitting head of a knitting machine for manufacturing flexible hoses (1) with a knitted reinforcement layer, which comprises a guide body (14) with a central tubular conduit (15) for the passage of the bearing layer (2) and having a outlet end portion (16) with a first outer peripheral surface (17) having a first predetermined radius (r1), a plurality of knitting needles (18) arranged along the periphery of said end portion (16) of said conduit (15) and having first longitudinal end sections (18') arranged along the circumference of said outer peripheral surface (17) and second longitudinal end sections (18″) arranged over a second cylindrical surface (19) having a second radius (r2) greater than said first radius (r1), at least one disk-shaped cam element (22), which is adapted to rotate at a first rotation speed and has a third predetermined radius (r3). The third radius (r3) is greater than said second radius (r2), connection means (23) being provided for connecting said disk-shaped element (22) to said second end sections (18″) of said needles (18), said connection means (23) having at least one longitudinal portion (24) with a radial dimension decreasing from said third radius (r3) to said second radius (r2).

An apparatus for closing a toe end of a tubular hosiery body includes a stitching device having a main body, a fixed reed, a movable reed pivoted to the fixed reed, and a main drive assembly for driving the movable reed to rotate relative to the fixed reed between juxtaposed and stacked positions. A rotary control unit includes a support frame supporting the main body, a rotary disc attached to the main body, a plurality of detent members disposed around the rotary disc, and a plurality of control drive members respectively driving the detent members. The control drive members consecutively operate to consecutively actuate the respective detent members such that the rotary disc together with the stitching device consecutively produces a limited amount of rotation in an intermittent manner.

Sinker cam segments in a circular knitting machine are located with respect to the generally radial direction by a generally radially inwardly facing location surface disposed radially outward of the segments. Each segment's radially outer end defines a contact region that abuts the locating surface. The contact region can be complementary surface contour to that of the locating surface, or a pair of discrete, spaced contact points protruding out from the radially outer end of the segment. The contact region is a reference for positioning the sinker cam segment with respect to the generally radial direction.

In the case of a single circular knitting machine consisting of a central rotatable needle cylinder (Z), around which a sinker ring (PR) comprising sinkers (P) as well as stationary cam systems (S) are arranged, which act on the needles (1), which are in each case assigned to the sinkers (P) and which can be moved vertically up and down, so as to replace the pitches, which hit one another rigidly, with a sinker grid system, which is flexible per se, which is automatically oriented in the needle gaps, a rocker (44) comprising an upper and a lower control bump (45) being provided in each case on the end of the sinkers (P), which is spaced apart from the needle, the sinker ring (PR), at the end below the sinkers (P), which is spaced apart from the needle, is embodied as a pivot point projection (40) comprising pivot point slits (41), in which the sinkers (P) are accommodated with their pivot inlet (43) so that they are capable of being tilted and the sinkers (P) being are laterally fixed in the needle gaps with sliding noses (47) at the end, which is spaced apart from the needle, transport the last knitting loops to the needle shaft (1) behind the needle latches in response to the knitting loop formation.

A two stage scrubber process for ethanol fermentation has a first stage using fusel oil to remove the hazardous air pollutants and recover the majority of the ethanol. A second stage uses water as the scrubbing solvent to recover any residual ethanol that is stripped from the first stage.

A method of converting a conventional atmospheric frying device to a vacuum frying device is provided. The method includes positioning a hood on top of a conventional frying device to provide an enclosure for drawing a vacuum within the modified devices. In addition, the method can include strengthening the existing vat so that it is capable of withstanding the forces associated with vacuum frying.

A coffee machine comprises a frothing device, wherein an internal milk channel leading to a frothing chamber is provided into which opens a bypass air inlet for operable air supply to the frothing device. A flexible milk suction line connects the frothing device with a milk supply container. Means are provided for cleaning the frothing device and the milk suction line with rinsing water from a continuous-flow water heater of the coffee machine. A controlled valve arrangement is provided which feeds rinsing water from the continuous-flow water heater to the bypass air inlet of the frothing device. A milk suction end of the milk suction line is directly or indirectly, fluid-conductively connectable with a residual water pan of the coffee machine prior to feeding rinsing water to the bypass air inlet.

A beverage machine for preparing and dispensing a hot beverage having a pump dispensing system. Hot water passes through a water distributor to infuse material in a filter basket. A coffee tank receives the brewed beverage and maintains it at an appropriate temperature. On demand, a pump dispensing system delivers the beverage through an outlet chamber and spout into a user's cup. The user manipulates a switch to vary the rate at which the pump dispensing system dispenses the beverage.

The disclosure provides methods and compositions for suppressing retroviruses, including novel methods for treating a retroviral infection in a human in need of such treatment, comprising delivering a functional meiosis arrest female protein 1 (MARF1) to cells containing a retroviral provirus, together with novel expression constructs comprising a coding sequence encoding a functional MARF1 operatively linked to a promoter, vectors comprising such constructs, and packaging cell lines for use in making such vectors.

The present invention provides compositions and methods relating to or derived from antigen binding proteins capable of inducing B-Klotho, and or FGF21-like mediated signaling. In embodiments, the antigen binding proteins specifically bind to a complex comprising β-Klotho and at least one of (i) FGFR1c, (ii) FGFR2c and (iii) FGFR3c. In some embodiments the antigen binding proteins induce FGF21-like signaling. In some embodiments, an antigen binding protein is a fully human, humanized, or chimeric antibodies, binding fragments and derivatives of such antibodies, and polypeptides that specifically bind to a complex comprising β-Klotho and at least one of (i) FGFR1c, (ii) FGFR2c and (iii) FGFR3c. Other embodiments provide nucleic acids encoding such antigen binding proteins, and fragments and derivatives thereof, and polypeptides, cells comprising such polynucleotides, methods of making such antigen binding proteins, and fragments and derivatives thereof, and polypeptides, and methods of using such antigen binding proteins, fragments and derivatives thereof, and polypeptides, including methods of treating or diagnosing subjects suffering from type 2 diabetes, obesity, NASH, metabolic syndrome and related disorders or conditions.

The invention provides compositions and methods for treating leukemia, for example, acute myeloid leukemia (AML) and B-cell acute lymphoid leukemia (B-ALL). The invention also relates to at least one chimeric antigen receptor (CAR) specific to CD123, vectors comprising the same, and recombinant T cells comprising the CD123 CAR. The invention also includes methods of administering a genetically modified T cell expressing a CAR that comprises a CD123 binding domain. The invention also includes methods of bone marrow ablation for use in treatments necessitating bone marrow reconditioning or transplant.

The present disclosure provides compositions and methods of use involving binding proteins, e.g., antibodies and antigen-binding fragments thereof, that bind to the matrix metalloproteinase-9 (MMP9) protein (MMP9 is also known as gelatinase-B), such as where the binding proteins comprise an immunoglobulin (Ig) heavy chain (or functional fragment thereof) and an Ig light chain (or functional fragment thereof).

Provided herein are methods of treatment to regenerate, restore or rejuvenate a tissue. Methods include making adult somatic and germ cells pluripotent for administration to a patient. Alternatively, created pluripotent cells may be differentiated to the desired tissue type and administered to a patient to repair or enhance the target tissue.

Materials and methods for treating and preventing American Foulbrood disease in honeybees, such as materials and methods for using phage lysin enzymes to lyse Paenibacillus larvae, are provided herein.

In one aspect, the invention relates to a method of loading exosomes with oligonucleotide cargo, by incubating an oligonucleotide comprising one or more hydrophobic modifications with a population of exosomes for a period of time sufficient to allow loading of the exosomes with the oligonucleotide. Exosomes loaded with hydrophobic ally modified oligonucleotide cargo, and uses thereof, are also provided.

The invention provides for a proteomic approach for identification of specific bacterial protein profiles that may be used in the development of methods for the diagnosis of bacterial chronic sinusitis. The invention provides for methods for determining the presence of pathogenic bacteria in the upper respiratory tract of a subject using protein profiles of the pathogenic bacteria. The invention also provides for methods of diagnosing a bacterial infection of the upper respiratory tract of a subject using protein profiles of a pathogenic bacteria. In addition, the invention provides for devices, immunoassays and kits for identifying pathogenic bacteria in the upper respiratory tract.

A cold rolling mill is described wherein the unstressed shape of metal sheet is continuously sensed during rolling by a plurality of negligible displacement force sensors perpendicularly disposed relative to the pass line at a mill location producing a tensile stress above 4,000 p.s.i. in the metal sheet being rolled. The output signals from those sensors underlying opposite edges of the metal sheet are compared to equalize reduction at the sheet edges while the difference between the force measured by a centrally situated sensor and the average force measured by the sensors underlying opposite edges of the sheet provide a signal indicative of the roll bending force required to produce flat sheet.

A device is disclosed for pressing objects by lifting the objects into a waiting pressing shaft. The shaft includes a forming element at its lower end for forming the object, and the shaft is engaged by its upper end through a pivot member to an air cylinder in a manner which provides a force advantage to the air cylinder. Also, a system for pressing objects is disclosed, in which the press device is employed in conjunction with a turntable for sequential and continuous pressing operations.

A machine for automatically joining front and back parts of buttons employs a turntable with nests that are rotated through a series of stations at which the parts are placed in the nests in a desired orientation, joined, and checked for defects. Orientation of the parts is achieved by video imaging of a first part as it is randomly placed in a nest, and computer-controlled placement of the second part based on the ascertained position of the first part.

A method and apparatus for substantially automatically joining front and back parts of buttons employs a turntable with retaining means that are rotated through a series of stations at which the parts are placed in the retaining means in a desired orientation, joined, and checked for defects. A human operator places button front parts at a first station, and the remaining stations carry out the assembly and quality control steps automatically. Placement at the first station determines the alignment and orientation of the two buttons.

A button making device capable of simply exchanging a first pressed mold, a second pressed mold, and a pressing mold so as to produce buttons of different sizes; a polygonal button whose front surface plate is dome-wise curved and has its shape fixed; and such a button making device, are provided. The button making device has a sliding platform, two pressed molds, a fixed member, a pressing shaft, a pressing mold, and an operation mechanism. The pressed molds are provided on an attachment member which is removably attached to the sliding platform. The pressing mold is removably attached to a lower end of the pressing shaft using magnetic force. The present invention can be used for a button making device which can easily form a metal button by press processing which can be used as an accessory adhered to clothes or the like by a pin or the like.

Gender specific synthetic nutritional compositions for female or male infants up to 1 month of age wherein, the concentration of alanine, and/or histidine, and/or isoleucine, and/or proline, and/or valine is adapted based on that found in HM produced for an infant of the same gender and age, and nutritional systems comprising them.

The invention concerns a sweetened dairy product comprising a dairy material, at least one steviol glycoside, at least one additive selected from a polysaccharide of fructose units and a salt.

Cat food products are provided. The cat food product may comprise a single sealed container comprising 10 g to 40 g of a complete and balanced semi-moist or wet cat food, or may comprise a plurality of such sealed containers. Methods of providing a cat food are also provided and comprise filling a container with from 10 g to 40 g of a complete and balanced semi-moist or wet cat food and sealing the container.

The present invention relates to protein compositions. In particular, the invention relates to a method for the production of a composition comprising casein fibrils. Further aspects of the invention area composition comprising casein fibrils, the use of such a composition and a food product comprising the composition.

Gender specific synthetic nutritional compositions for infants up to 1 month of age wherein, the total protein content is adapted based on that found in HM produced for infants of the same gender and age, and nutritional systems comprising them.

Disclosed herein is a nutrient delivery system that provides a nutritional formula for consumption. The nutrient delivery system includes a pod and a nutritional powder comprising at least one phospholipid. The nutritional formula has improved characteristics, such as decreased foaming.

The present invention is directed to a Modular Liquid Infusing, Flavoring and Dispensing Device that provides a means to infuse flavor into liquids for variable periods of time prior to dispensing, and after the brewing process, wherein the system provides a means to control the rate at which the liquid is dispensed, reduces the trauma to the dispensed liquid, and reduces the amount of foaming in the dispensed liquid. The present invention further provides a method for using the Modular Liquid Infusing, Flavoring, and Dispensing Device.

A device that automatically actuates the reversing lever of a ratchet mechanism when the radial direction of the motor is changed. The auto-shift mechanism includes a worm gear that rotates with the motor, and a disc coupled to the worm gear that moves laterally as the worm gear rotates. Axial movement of the disc actuates a reversing lever of a ratchet mechanism by either pulling or pushing the reversing lever. A lost-motion mechanism can absorb an initial amount of torque so that the auto-shift mechanism can run its course prior to applying the torque to a fastener.

A dual-pawl ratchet wrench mechanism is disclosed having a stop mechanism for limiting over-travel of a reversing lever for selecting drive directions. The stop mechanism is formed on a disc is selectively engageable with first and second pawls to move the pawls into and out of engagement with a ratchet gear to determine a torque drive direction, the ratchet gear capable of providing torque to a working piece in the selected drive direction. The design simplifies manufacturing. Additionally, the reversing lever is assembled with the mechanism in a manner to improve sealing.

A girdle band for underwear connection and a processing method thereof, the girder band has a baseband with upper and lower overturning edges, a plurality of snap rings, surface cloth and a shaping layer, and the processing method has the following steps: firstly respectively connecting both surfaces of the lower overturning edge of the baseband with the shaping layer and the first strip of the surface cloth; sewing the bottom surface of the second strip of the surface cloth with the shaping layer; forming the upper and the lower overturning edges; and using an ultrasonic wave cutting machine for cutting the long strip-shaped baseband into girdle band units. The girdle band has the advantages of no sewing joints on the back surface and good appearance effect, and can avoid skin injuries.

An embroidery data processor includes a color information acquiring unit configured to acquire color information of a workpiece cloth on which an embroidery pattern composed of a plurality of color-based pattern portions is sewn, a color storage unit configured to store data of defined colors, an assignment unit configured to randomly extract colors from the colors stored by the color storage unit for every color-based pattern portion, the extracted colors being used as thread color data specifying colors of the color-based pattern portions respectively, the assignment unit assigning the extracted colors to the respective color-based pattern portions, and a setting unit configured to set a predetermined extraction range containing a similar color or a contrast color based on the color information acquired by the acquiring unit. The assignment unit is configured to extract the color stored by the color storage unit in the set extraction range.

A punching device including a punching die (5a) that can be connected to the needle bar and a punching matrix (5b) that can be fastened to a needle plate (7) of a sewing machine. The punching matrix (5b) is embodied as a lid of a clippings container (9). The planar object (23) to be processed is displaced via the tambour frame in a punching plane L2, with this punching plane L2 being arranged parallel above the sewing plane L1.

A method for fabricating a repair laminate for a composite part having an exposed surface includes applying a bonding material to the exposed surface and forming an uncured ply stack assembly on the bonding material. The uncured ply stack assembly is formed by forming and compacting a series of uncured ply stacks. The ply stack assembly and bonding material are then cured.

A thin film forming apparatus and a thin film forming method using the same are disclosed. In one aspect, the thin film forming apparatus comprises a mask that includes a blocking portion and an opening. It also includes an etching source that jets an etching gas through the opening of the mask to etch a thin film according to a pattern. The mask includes a gas blower for blowing a gas around the opening so that the etching gas does not penetrate into a thin film area corresponding to the block portion. When the thin film forming apparatus is used, a normal residual area of a thin film may be safely preserved and patterning may be accurately performed. Thus, the quality of a product manufactured by using the thin film forming apparatus may be improved.

The object of the invention is to provide a plasma processing apparatus having enhanced plasma processing uniformity. The plasma processing apparatus comprises a processing chamber 1, means 13 and 14 for supplying processing gas into the processing chamber, evacuation means 25 and 26 for decompressing the processing chamber 1, an electrode 4 on which an object 2 to be processed such as a wafer is placed, and an electromagnetic radiation power supply 5A, wherein at least two kinds of processing gases having different composition ratios of O2 or N2 are introduced into the processing chamber through different gas inlets so as to control the in-plane uniformity of the critical dimension while maintaining the in-plane uniformity of the process depth.

A system for fluid partitioning for chemical amplification or other chemical processing or separations of a sample, comprising a first dispenser of a first polymeric sheet, wherein the first polymeric sheet contains chambers; a second dispenser of a second polymeric sheet wherein the first dispenser and the second dispenser are positioned so that the first polymeric sheet and the second polymeric sheet become parallel; a dispenser of the fluid positioned to dispense the fluid between the first polymeric sheet and the second polymeric sheet; and a seal unit that seals the first polymeric sheet and the second polymeric sheet together thereby sealing the sample between the first polymeric sheet and the second polymeric sheet and partitioning the fluid for chemical amplification or other chemical processing or separations.

The present invention provides a method for bonding two substrates using a UV radiation curing-redox curing adhesive system having a shadow area and a transparent area, comprising: bonding the shadow area of the substrates using a redox curing adhesive system, and bonding the transparent area of the substrates using a liquid optically clear adhesive containing UV initiators.

The invention relates to a method for connecting a first tube to a second tube, the tubes being interconnected in an overlapping region by means of an adhesive that fills a gap in the overlapping region between the tubes. Said method is characterized in that: a) adhesive is applied to the overlapping region of at least one of the tubes and the adhesive is selected in such a way that it is solid at temperatures of below 30° C. after application to the overlapping region and prior to the connection of the tubes, and cannot be cured without thermal activation; b) the tube having the adhesive in the overlapping region is pushed onto or inside the other tube; c) the tubes are fixed in relation to one another in the overlapping region by a heatable clamp, said clamp being designed in such a way that it can heat the tubes in said region; d) the adhesive is thermally activated by heating the overlapping region with the aid of the heatable clamp, whereby the adhesive cures and connects the two tubes in the overlapping region; and e) the heatable clamp is removed once the adhesive has cured. The invention also relates to a method for producing a refrigerator and to a refrigerator comprising correspondingly joined tube sections.