no Pilgrims visiting Sabarimala to get nowcast from Nov. 15 By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:18:46 +0530 Hygrometers to measure humidity and thermometers will be installed on the shrine premises soon to provide weather services to pilgrims, says IMD Director Full Article Kerala
no NIFT’s craft cluster projects enriching J&K’s artisans, crafts: L-G Manoj Sinha By www.thehindu.com Published On :: Thu, 14 Nov 2024 07:46:32 +0530 He described J&K as “a repository of Indian creative traditions Full Article India
no BJP’s win in recent polls is expression of people’s faith in govt. policies: Haryana Governor By www.thehindu.com Published On :: Thu, 14 Nov 2024 07:50:35 +0530 Full Article Haryana
no Mamata calls for unity of hills and plains; focuses on development in north Bengal By www.thehindu.com Published On :: Thu, 14 Nov 2024 07:55:01 +0530 This is her first official visit to Darjeeling in two years; she did not go to the hills even during the 2024 Lok Sabha election campaigns Full Article West Bengal
no ISB Insights Forum 2024 to be held on November 15 By www.thehindu.com Published On :: Wed, 13 Nov 2024 18:33:55 +0530 Full Article Telangana
no Google.org awards USD 1 mn grant to Karya to boost ai-based economic opportunities for low-income communities By www.newkerala.com Published On :: Wed, 13 Nov 2024 17:40:02 +0530 Full Article
no LTIMindtree expands footprint in US with new innovation facility By www.newkerala.com Published On :: Wed, 13 Nov 2024 18:04:02 +0530 Full Article
no A multifunctional “three-in-one” fluorescent theranostic system for hepatic ischemia–reperfusion injury By pubs.rsc.org Published On :: Chem. Sci., 2024, Advance ArticleDOI: 10.1039/D4SC04962D, Edge Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Jihong Liu, Dongni Yin, Wen Zhang, Xin Wang, Tony D. James, Ping Li, Bo TangA single-component multifunctional fluorescent theranostic system (MB-Gly) for use during hepatic ischemia-reperfusion injury (HIRI) has been developed.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
no BRO rescues 20 vehicles stuck in snow in J-K's Bandipora By www.newkerala.com Published On :: Wed, 13 Nov 2024 19:12:01 +0530 Full Article
no There will be census in country but not based on caste: Union Minister Shobha Karandlaje By www.newkerala.com Published On :: Wed, 13 Nov 2024 19:18:02 +0530 Full Article
no Akashteer: Transforming India's air defence with cutting-edge technology By www.newkerala.com Published On :: Wed, 13 Nov 2024 19:26:02 +0530 Full Article
no AI and hi-tech technologies will be used in CCTV arrangements: UP DGP Prashant Kumar on Mahakumbh 2025 preparations By www.newkerala.com Published On :: Wed, 13 Nov 2024 19:40:02 +0530 Full Article
no Assam Governor attends Sainik school Goalpara's Diamond Jubilee celebrations By www.newkerala.com Published On :: Wed, 13 Nov 2024 19:42:03 +0530 Full Article
no No gaps in management of biodegradable waste, Kerala tells NGT By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:23:47 +0530 Full Article Kerala
no Lebanon media claims Israeli strike hit apartment south of Beirut By www.thehindu.com Published On :: Wed, 13 Nov 2024 15:10:43 +0530 Israeli warplanes launched a strike at dawn targeting a residential apartment in a building in the Dawhet Full Article World
no Sri Lanka to hold key parliamentary vote on November 14 By www.thehindu.com Published On :: Wed, 13 Nov 2024 20:35:59 +0530 President Anura Kumara Dissanayake’s ruling alliance is looking to secure a majority in Parliament Full Article World
no Furoxan–piplartine hybrids as effective NO donors and ROS inducers in PC3 cancer cells: design, synthesis, and biological evaluation By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3778-3794DOI: 10.1039/D4MD00281D, Research ArticleCarolyne Brustolin Braga, Julio Cesar Milan, Matheus Andrade Meirelles, Bruno Zavan, Guilherme Álvaro Ferreira-Silva, Ester Siqueira Caixeta, Marisa Ionta, Ronaldo A. PilliA novel hybrid integrating piplartine with a furoxan moiety exhibited a sub-micromolar IC50 and extraordinary selectivity for PC3 cells, which was associated with its capacity to release NO, generate ROS, induce DNA damage, and trigger apoptosis.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
no Pyridinyl 4-(2-oxoalkylimidazolidin-1-yl)benzenesulfonates and their hydrochloride salts as novel water soluble antimitotic prodrugs bioactivated by cytochrome P450 1A1 in breast cancer cells By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3728-3745DOI: 10.1039/D4MD00476K, Research ArticleVincent Ouellette, Chahrazed Bouzriba, Atziri Corin Chavez Alvarez, Quentin Bruxelles, Geneviève Hamel-Côté, Sébastien FortinNew water soluble antimitotic CYP1A1-activated prodrugs named PYRAIB-SOs and their hydrochlorides targeting breast cancers.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
no Design and synthesis of novel multi-target tetrabromophthalimides as CBS and Topo-II inhibitors and DNA intercalators By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3800-3816DOI: 10.1039/D4MD00585F, Research ArticleMarwa Abdel-Motaal, Dalal Ali Aldakhili, Ayman B. Farag, Ayman Abo Elmaaty, Marwa Sharaky, Nadia A. Mohamed, Saad Shaaban, Abdullah Yahya Abdullah Alzahrani, Ahmed A. Al-KarmalawyNovel multi-target tetrabromophthalimides as CBS and Topo-II inhibitors and DNA intercalators.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
no Prediction of synergistic gemcitabine-based combination treatment through a novel tumor stemness biomarker NANOG in pancreatic cancer By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3853-3861DOI: 10.1039/D4MD00165F, Research ArticleJiongjia Cheng, Ting Zhu, Shaoxian Liu, Jiayu Zhou, Xiaofeng Wang, Guangxiang LiuThe synergistic effect observed in gemcitabine-based combination therapies targeting pancreatic cancer stem cells was correlated with the inhibiting effect on the expression of stemness-related gene NANOG.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
no Novel PROTAC probes targeting KDM3 degradation to eliminate colorectal cancer stem cells through inhibition of Wnt/β-catenin signaling By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3746-3758DOI: 10.1039/D4MD00122B, Research Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Shadid U. Zaman, Piyusha P. Pagare, Hongguang Ma, Rosalie G. Hoyle, Yan Zhang, Jiong LiWe designed and synthesized novel IOX1-based PROTACs, which can selectively degrade KDM3A and KDM3B to eliminate colorectal cancer stem cells through inhibition of Wnt signaling.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
no Evaluating the therapeutic potential of genetically engineered probiotic Zbiotics (ZB183) for non-alcoholic steatohepatitis (NASH) management via modulation of the cGAS-STING pathway By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3817-3836DOI: 10.1039/D4MD00477A, Research ArticleMaha Saad, Walaa Ibrahim, Amany Helmy Hasanin, Aya Magdy Elyamany, Marwa MatboliZBiotics administration in the NASH model downregulated the RNA panel (MAPK3, EDN1, TNF, miR-6888-5p, lncRNA RABGAP1L-DT-206), restored intestinal barrier integrity, reduced hepatic inflammation, and improved lipid profiles and liver enzymes.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
no Design and synthesis of novel 8-(azaindolyl)-benzoazepinones as potent and selective ROCK inhibitors By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3862-3879DOI: 10.1039/D4MD00313F, Research ArticleDaniele Pala, David Clark, Christine Edwards, Elisa Pasqua, Laura Tigli, Barbara Pioselli, Piotr Malysa, Fabrizio Facchinetti, Fabio Rancati, Alessandro AccettaThis study reports a novel, potent and selective series of ROCK inhibitors based on 8-(azaindolyl)-benzoazepinones identified through a core-hopping strategy.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
no Advances in Detecting Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Using Molecular Receptors and Nanostructured Assemblies By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4MD00661E, Review ArticleAvijit Kumar DasThe detection and quantification of non-steroidal anti-inflammatory drugs (NSAIDs) are crucial due to their widespread use and potential impact on human health and the environment. This review provides a comprehensive...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
no Supreme Court stays order for CBI probe into sexual assault of minor in Chennai By www.thehindu.com Published On :: Wed, 13 Nov 2024 13:07:47 +0530 Calls for a list of five to seven direct recruit IPS officers, including three women, who hail from other States but are now serving in Tamil Nadu cadre Full Article Tamil Nadu
no Amaran is a film about a soldier’s life, nothing more: Seeman By www.thehindu.com Published On :: Wed, 13 Nov 2024 14:55:42 +0530 Full Article Tamil Nadu
no AIADMK will not form an alliance with BJP in 2026 polls, reiterates Palaniswami By www.thehindu.com Published On :: Wed, 13 Nov 2024 16:30:55 +0530 “During the Lok Sabha election, it was said at the party headquarters and in press bytes that the AIADMK will not have alliance with the BJP in the [2026] Assembly election,” he said Full Article Tamil Nadu
no Tamil Nadu CM Stalin to launch Phase II of nutritional intervention programme for malnourished children, mothers By www.thehindu.com Published On :: Wed, 13 Nov 2024 17:23:48 +0530 Mothers of over 76,700 babies in the age group of zero to six months, identified as malnourished, would be covered under Phase II of the programme Full Article Tamil Nadu
no DUSU election results to be announced on November 21 By www.thehindu.com Published On :: Wed, 13 Nov 2024 13:18:26 +0530 The counting of votes for both the central panel and college representatives will begin at 8:30 a.m. on November 21 at the DU Conference Centre Full Article Delhi
no Centre’s nod sought for Vizag Metro, MA&UD Minister informs A.P. Assembly By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:55:45 +0530 The revised cost estimate stands at ₹17,232 crore; the project is initially proposed to come up in two phases with four corridors spanning a total length of 76 km Full Article Andhra Pradesh
no Varun Hospitality announces eco-friendly mixed-use project to replace The Gateway Hotel in Visakhapatnam By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:28:31 +0530 Full Article Andhra Pradesh
no IMD forecasts onset of winter in Telangana by November-end By www.thehindu.com Published On :: Wed, 13 Nov 2024 11:22:39 +0530 Full Article Telangana
no Hyderabad to get regional centre of Indian Institute of Creative Technology By www.thehindu.com Published On :: Wed, 13 Nov 2024 17:34:11 +0530 All activities are going to start quickly. The facility in Hyderabad will be set up in the IMAGE Tower, said Secretary, Union Ministry of Information and Broadcasting Full Article Hyderabad
no Hyderabad Airport wins global recognition for digital innovations By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:14:32 +0530 Full Article Hyderabad
no Metro Rail services to be extended to Medchal and other parts of northern Hyderabad under Phase-III: Telangana CM By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:18:36 +0530 Full Article Hyderabad
no 29th Climate Conference (COP) tracker | Day 2 LIVE: Key speeches, UK NDC, and India’s reaction at 5 p.m. on November 13 By www.thehindu.com Published On :: Wed, 13 Nov 2024 17:01:23 +0530 Vibhuti Garg, an Associate and Senior Energy Specialist with over 13 years of experience in the energy sector, will guide us through the implications of these financial negotiations and the potential impacts on global energy transitions and climate commitments at 5 p.m. on November 13 Full Article Environment
no Synthesis of MOF-supported Pt catalyst with high electrochemical oxidation activity for methanol oxidation By pubs.rsc.org Published On :: RSC Adv., 2024, 14,36370-36377DOI: 10.1039/D4RA06393G, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Merve Akin, Hatice Kars, Muhammed Bekmezci, Aysenur Aygun, Mert Gul, Guray Kaya, Fatih SenIn this study, Pt and Pt@Ti-MOF NPs catalysts were synthesized by chemical reduction method. Ti-MOF structure was synthesized using the solvothermal method, and the effect of Ti-MOF on methanol oxidation was investigated.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
no Karnataka bypolls: Channapatna, Shiggaon and Sandur constituencies witness overall turnout of 76.9% till 5 p.m. By www.thehindu.com Published On :: Wed, 13 Nov 2024 10:37:35 +0530 A total of 45 candidates are in the fray in these byelections Full Article Karnataka
no Karnataka Chief Minister Siddaramaiah says no proposal to ease night traffic ban through Bandipur By www.thehindu.com Published On :: Wed, 13 Nov 2024 14:45:12 +0530 Deputy Chief Minister D.K. Shivakumar had stated, in Wayanad in Kerala, that the government would take all possible measures to lift night traffic ban through Bandipur, which had riled wildlife conservationists in Karnataka Full Article Karnataka
no No dearth of funds for development works: CM By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:39:24 +0530 Full Article Karnataka
no 80.48% voter turnout recorded in Shiggaon By www.thehindu.com Published On :: Wed, 13 Nov 2024 20:51:07 +0530 The polling for the byelection to Shiggaon Legislative Assembly Constituency in concluded peacefully with large number of voters turning up at 241 polling stations in the assembly segment to exercise their franchise on Wednesday Full Article Karnataka
no Kannada has survived because of native speakers from North Karnataka: Horatti By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:05:42 +0530 Full Article Karnataka
no Carlsen in focus as top stars vie for honours By www.thehindu.com Published On :: Wed, 13 Nov 2024 12:19:50 +0530 The focus, of course, will be very much on Carlsen, who is returning to the tournament that he won in convincing fashion in 2019 Full Article Sport
no Comeback man Shami hogs the spotlight as MP takes honours on opening day against Bengal By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:38:38 +0530 Full Article Sport
no MobiKwik sees no business impact due to RBI’s P2P diktat, Co-Founder Taku says By www.thehindubusinessline.com Published On :: Wed, 13 Nov 2024 09:57:54 +0530 Revenue likely to grow over 50 per cent for many years, Taku says Full Article Companies
no Ennoventure bags $8.9 million in Series A led by Tanglin Venture Partners By www.thehindubusinessline.com Published On :: Wed, 13 Nov 2024 10:50:10 +0530 The round included participation from existing investors, such as Fenice Investment Group and additional SAFE investors Full Article Companies
no The globally-acclaimed Candlelight Concert is now in Chennai. Listen to classical and contemporary music at Museum Theatre, amidst thousands of candles By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:12:01 +0530 The first concert on November 15 will feature tunes from Tamil and Hindi films, followed by tributes to Coldplay, Mozart, Queen, and Abba in the upcoming months Full Article Life & Style
no Yet another incident of doctor being attacked By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:22:03 +0530 Full Article Chennai
no U.T. seeks Centre’s nod to implement Smart Meter Project with post-paid plan option By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:27:15 +0530 There is stiff resistance from various quarters for the pre-paid Smart Meter Project. It will be difficult to introduce the prepaid functionality at the beginning stages of the implementation, says Minister for Home A. Namassivayam in his memorandum submitted to Union Minister for Power Manohar Lal Khattar Full Article Puducherry
no On the Draw — November 13, 2024 By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:36:44 +0530 Full Article Cartoon