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Comparative Genomic Analysis of Third Generation Cephalosporin-Resistant Escherichia coli Harboring blaCMY-2-Positive IncI1 group, IncB/O/K/Z, and IncC Plasmids Isolated from Healthy Broilers in Japan. [Epidemiology and Surveillance]

The off-label use of third generation cephalosporin (3GC) during in ovo vaccination or vaccination of newly hatched chicks, was a common practice worldwide. CMY-2-producing Escherichia coli have been disseminated among broiler production. The objectives of this study were to determine the epidemiological linkage of blaCMY-2-positive plasmids among broilers both within and outside Japan because grandparent stock and parent stock were imported in Japan. We examined the whole genome sequences of 132 3GC-resistant E. coli isolates collected from healthy broilers during 2002-2014. The predominant 3GC-resistance gene was blaCMY-2, which was detected in the plasmids of 87 (65.9%) isolates. The main plasmid replicon types were IncI1-I (n=21; 24.1%), IncI (n=12; 13.8%), IncB/O/K/Z (n=28; 32.2%), and IncC (n=22; 25.3%). Those plasmids were subjected to gene clustering and network analyses and plasmid multi-locus sequence typing (pMLST). The chromosomal DNA of isolates was subjected to MLST and single nucleotide variant (SNV)-based phylogenetic analysis.

MLST and SNV-based phylogenetic analysis revealed high diversity of E. coli isolates. ST429 harboring blaCMY-2-positive IncB/O/K/Z was closely related to isolates from broiler in Germany harboring blaCMY-2-positive IncB/O/K/Z. pST55-IncI and pST12-IncI1-I and pST3-IncC were prevalent in western Japan. pST12-IncI1-I and pST3-IncC were closely related to those detected in E. coli isolates from chicken in American continent, whereas 26 IncB/O/K/Z were related to those in Europe. These data will be useful to reveal the whole picture of transmission of CMY-2-producing bacteria in and out of Japan.




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Dietary Fats and Atherosclerosis From Childhood to Adulthood

BACKGROUND:

The association of dietary fat distribution with markers of subclinical atherosclerosis during early life is unknown. We examined whether success in achieving the main target of an infancy-onset dietary intervention based on the distribution of dietary fat was associated with aortic and carotid intima-media thickness (IMT) and distensibility from childhood to young adulthood.

METHODS:

In the prospective randomized controlled Special Turku Coronary Risk Factor Intervention Project trial, personalized dietary counseling was given biannually to healthy children from infancy to young adulthood. The counseling was based on Nordic Nutrition Recommendations, with the main aim of improving the distribution of dietary fat in children’s diets. IMT and distensibility of the abdominal aorta and common carotid artery were measured repeatedly at ages 11 (n = 439), 13 (n = 499), 15 (n = 506), 17 (n = 477), and 19 years (n = 429). The targeted distribution of dietary fat was defined as a ratio of saturated fatty acids to monounsaturated and polyunsaturated fatty acids of <1:2 and as an intake of saturated fatty acids of <10% of energy intake. Participants who met ≥1 of these 2 criteria were defined to achieve the main intervention target.

RESULTS:

Individuals who achieved the main intervention target had lower aortic IMT (age- and sex-adjusted mean difference 10.4 µm; 95% confidence interval: 0.3 to 20.5 µm) and better aortic distensibility (0.13% per 10 mm Hg; 95% confidence interval: 0.00% to 0.26% per10 mm Hg) compared with their peers who did not meet the target.

CONCLUSIONS:

Achieving the main target of an infancy-onset dietary intervention, reflecting dietary guidelines, was favorably associated with aortic IMT and distensibility during the early life course. These data support the recommendation of favoring unsaturated fat to enhance arterial health.




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Trends in Pediatric Malpractice Claims 1987-2015: Results From the Periodic Survey of Fellows

BACKGROUND:

Pediatricians are less frequently sued than other physicians. When suits are successful, however, the average payout is higher. Little is known about changes in the risk of litigation over time. We sought to characterize malpractice lawsuit trends for pediatricians over time.

METHODS:

The Periodic Survey is a national random sample survey of American Academy of Pediatrics members. Seven surveys between 1987 and 2015 asked questions regarding malpractice (n = 5731). Bivariate and multivariable analyses examined trends and factors associated with risk and outcome of malpractice claims and lawsuits. Descriptive analyses examined potential change in indemnity amount over time.

RESULTS:

In 2015, 21% of pediatricians reported ever having been the subject of any claim or lawsuit, down from a peak of 33% in 1990. Report of successful outcomes in the most-recent suit trended upward between 1987 and 2015, greatest in 2015 at 58%. Median indemnity was unchanged, averaging $128 000 in 2018 dollars. In multivariate analysis, male sex, hospital-based subspecialty (neonatology, pediatric critical care, pediatric emergency medicine, and hospital medicine), longer career, and more work hours were associated with a greater risk of malpractice claim.

CONCLUSIONS:

From 1987 to 2015, the proportion of pediatricians sued has decreased and median indemnity has remained unchanged. Male pediatricians and hospital-based subspecialists were more likely to have been sued. Greater knowledge of the epidemiology of malpractice claims against pediatricians is valuable because it can impact practice arrangements, advise risk-management decisions, influence quality and safety projects, and provide data to guide advocacy for appropriate tort reform and future research.




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Fin24.com | What to know about shift from equities to 'safety' of bonds

Geopolitical factors and economic uncertainty make some investors shift away from equities into what they perceive to be the safety of higher-quality bonds.




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Hacked and Cut Off From the Public: This Is School Board Business in the Coronavirus Crisis

Social distancing is forcing school business to be conducted virtually, putting school boards in the difficult spot of making crucial decisions on spending and other issues without the same level of public input.




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Mechanical Engineering department draws from existing success in online teaching

When the novel coronavirus pandemic prompted the transition to remote learning at Penn State, faculty and administrators in the Department of Mechanical Engineering were prepared for the challenge.




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STEM Education: Lessons From 20 Years of Data

For the first time, guest bloggers share analysis from 20 years of math and science international assessment data.




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How to Stream the Super Bowl From Anywhere

Getting ready for the big game? There are plenty of options, even if you're abroad. Here's how to watch in the states or bypass region blocking with a VPN to watch the Super Bowl.




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How to Copy Large Files From Your Phone to a Computer

There are plenty of ways to transfer large files between Windows, Mac, iOS, and Android devices, including AirDrop, Google Photos, Bluetooth transfer, and third-party programs.




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How to Run Windows 10 From a USB Drive

Loading and running Windows 10 from a USB drive is a handy option when you're using a computer saddled with an older version of Windows.




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LG TV Morphs From Flat Screen to Curved With Press of a Button

At CES, LG Display is showing off a 65-inch concept TV that can bend at the edges, allowing it to switch from a flat-screen display to a curved one in about five seconds. The company also put a bendable OLED on a foldable tablet/laptop.




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Former Hearts chairman Leslie Deans urges club to take legal action against SPFL and clubs who 'voted for Hearts ejection from league'

Former Hearts chairman Leslie Deans has urged the club to take legal action against the SPFL as well as those who voted to end the season early, effectively relegating the Jambos.




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Four fined for 800 mile round trip from London to Motherwell

A family of four was caught flouting lockdown restrictions after attempting to travel to Motherwell for a mini-break.




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Sixth resident dies from Covid-19 at Skye Home Farm care home where more than 50 have tested positive

A sixth resident has died from coronavirus in a care home on Skye.




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Berks faculty member coordinates mask donation from Reading Chinese Association

Hongyan “Red” Yuan, an instructional designer at Penn State Berks and member of the board of the Reading Chinese Association (RCA), recently helped to coordinate the donation of 1,500 surgical masks to Penn State Health St. Joseph.




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The Burden of Diabetes Mellitus Among US Youth: Prevalence Estimates From the SEARCH for Diabetes in Youth Study

SEARCH for Diabetes in Youth Study Group
Oct 1, 2006; 118:1510-1518
ARTICLES




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Mortality and Neonatal Morbidity Among Infants 501 to 1500 Grams From 2000 to 2009

Jeffrey D. Horbar
Jun 1, 2012; 129:1019-1026
ARTICLES




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Abnormal Pulmonary Outcomes in Premature Infants: Prediction From Oxygen Requirement in the Neonatal Period

Andrew T. Shennan
Oct 1, 1988; 82:527-532
ARTICLES




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Secondary Sexual Characteristics and Menses in Young Girls Seen in Office Practice: A Study from the Pediatric Research in Office Settings Network

Marcia E. Herman-Giddens
Apr 1, 1997; 99:505-512
ARTICLES




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Update on the 1987 Task Force Report on High Blood Pressure in Children and Adolescents: A Working Group Report from the National High Blood Pressure Education Program

National High Blood Pressure Education Program Working Group on Hypertension Control in Children and Adolescents
Oct 1, 1996; 98:649-658
ARTICLES




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The EPICure Study: Outcomes to Discharge From Hospital for Infants Born at the Threshold of Viability

Kate Costeloe
Oct 1, 2000; 106:659-671
ARTICLES




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A Simple Estimate of Glomerular Filtration Rate in Children Derived From Body Length and Plasma Creatinine

G. J. Schwartz
Aug 1, 1976; 58:259-263
ARTICLES




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Palivizumab, a Humanized Respiratory Syncytial Virus Monoclonal Antibody, Reduces Hospitalization From Respiratory Syncytial Virus Infection in High-risk Infants

The IMpact-RSV Study Group
Sep 1, 1998; 102:531-537
ARTICLES




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Neonatal Outcomes of Extremely Preterm Infants From the NICHD Neonatal Research Network

Barbara J. Stoll
Sep 1, 2010; 126:443-456
ARTICLES




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Save Up to 50 Percent on Almost Everything From Vistaprint

Start your new year off right by getting some new customized items for your business, or just treat yourself to a unique 2020 calendar of your own design, all for a fantastic price.




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Colombian archbishop removes from ministry 15 priests accused of sexual abuse

Villavicencio, Colombia, Apr 7, 2020 / 12:00 am (CNA).- The president of the Colombian bishops’ conference, Óscar Urbina, suspended 15 priests of his archdiocese from ministry who have been accused of sexual abuse. Other jurisdictions in the country have removed four other priests.

Archbishop Óscar Urbina of Villavicencio told Colombian media that the accused priests represent 15% of the city’s priests.

The priests are accused of committing sexual abuse in Colombia, Italy and the United States, Caracol Radio reported.

Fr. Carlos Villabón, communications director and chancellor for the archdiocese of Villavicencio, told ACI Prensa, CNA’s Spanish language news partner, that the 15 priests were suspended while a canonical investigation proceeds at the Vatican.

“On March 16, 2020 these 15 priests were notified after a preliminary investigation was carried out. They are neither convicted nor acquitted by this suspension, only asked to relinquish their parish duties, cease celebrating the Eucharist and cease their ministerial service while the complete investigation is conducted,” the priest explained.

The results of the preliminary investigation “are now being sent to the Congregation for the Doctrine of the Faith at the Vatican, and there they will determine the gravity of the facts and what the Church calls a penal canonical process will be conducted,” Villabón said.

“It’s unknown how much time the canonical process will take, but the idea is that it proceed as quickly as possible, considering that in Italy and in many parts of the world there’s a quarantine because of the coronavirus,” the communications director added.
Caracol Radio published a list of the 19 priests, but Villabón told ACI Prensa that the archdiocese would neither confirm nor deny the names reported.

 “According to a witness under protection by the prosecutor’s office, the 19 priests apparently formed a network of abusers, Caracol Radio reported.

In an April 3 statement, the archdiocese of Villavicencio announced that an accusation was received Feb. 14, 2020 concerning “acts against sexual morality by some priests of this archdiocese.”

“Having as a priority the alleged victim, we expressed to him our deep pain and solidarity and have offered him psychological and spiritual accompaniment. We reaffirm our commitment to act with clarity and transparency for his good and that of the Church,” the statement said.

Following the protocols of the Archdiocesan Commission for the Protection of Minors, once the abuse was reported, the regional prosecutor’s office was notified and “we made ourselves completely available to cooperate in the investigations taking place in this case,” the statement said.

The archdiocese said that it has taken steps “to eradicate the terrible evil of abuse within and outside our institution. We ask to be informed of any situations where one of our members has finally betrayed his vocation of service and dedication to the Lord and the community.”

A version of this story was first reported by ACI Prensa, CNA's Spanish-language news partner. It has been translated and adapted by CNA.

 




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LG Pulls Out From Mobile World Congress Over Coronavirus Fears

LG is skipping the event, citing the travel restrictions from the ongoing coronavirus outbreak. However, the GSMA still plans on holding the annual tech show, saying the outbreak has caused 'minimal impact' so far.




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The Phone From Pablo Escobar's Brother Is Just a Galaxy Fold Covered in Gold Foil

The new foldable phone from Pablo Escobar's brother is a Samsung Galaxy Fold with no changes to the software, according to a YouTuber and a journalist who obtained the products amid consumer worries the business is a scam.




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How to Do a Reverse Image Search From Your Phone

Google's reverse image search is a breeze on a desktop, but what about when you're on a mobile device? Google, Bing, and others have options.




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An update from Brandywine's Chancellor regarding COVID-19




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Books: What we can learn from the literature of imprisonment

The exercise yard lies just below my window. Every day I pace around it 12 times before returning to solitary confinement. The King George V park in Bearsden, of course, does not resemble the interior of any jail and the restrictions on my liberty are minor in comparison to those who have been imprisoned down the ages.




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Dutton Institute pulls from decades of experience to aid students

When Penn State decided in early March to cancel all in-person classes, staff at the Dutton Institute were already weeks into a plan to assist faculty members with the transition. They had the snow-day protocol complete with teaching tools from hundreds of learning designers with decades of experience creating courses for the virtual world.




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Roy Horn of 'Siegfried and Roy' fame dies from COVID-19 complications

Roy Horn was 75.




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Students With Disabilities Fear Fallout From College Admissions Scandal

Allegations that some students lied about having disabilities so they could get special accommodations on college entrance exams have the disabilities community worried about a backlash.




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Overhauling Student Assessments: A View From the Pilot's Seat

Louisiana and New Hampshire are among the handful of states that have stepped up to experiment with crafting new student assessments under the Every Student Succeeds Act.




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It's Official: All States Have Been Excused From Statewide Testing This Year

Within three weeks, a pandemic has completely changed the national landscape on testing. The U.S. Department of Education has now excused all 50 states and the District of Columbia from the requirement that they test all their students in math and English/language arts.




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From Puerto Rico to Penn State: A journey to becoming a student marshal

Daniela Claudio Pagán, a graphic design senior from Puerto Rico, has been named the College of Arts and Architecture's 2020 student marshal.




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How to Get the Best Cable Modem: Buy or Rent From Your ISP?

You may be able to save money and get faster speeds by buying a cable modem instead of renting one from your ISP. Here's what you need to know.




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1 in 4 Americans Would Refuse COVID-19 Vaccine from Government

Source: www.thegatewaypundit.com - Friday, May 08, 2020
One in Four Americans would refuse a COVID-19 vaccine according to a new ABC News/Ipsos poll. The news comes as Americans trust in the medical community continues to plunge thanks to overblown predictions on the extent of the coronavirus pandemic, fake news reporting and the continued attacks on hydroxychloroquine treatments that are showing great success. HUGE UPDATE: Dr. Fauci and Dr. Birx Used Imperial College Model — NOW CONFIRMED AS A COMPLETE FRAUD — To Persuade President Trump to Lock Down Entire US Economy! After losing your business and livelihood due to faulty models and predictions why would you trust the government with a COVID-19 vaccine? Via ABC Action News : Americans, by a large 30-point margin, are resistant to re-opening the country now, believing the risk to human life of opening the country outweighs the economic toll of remaining under restrictive lockdowns — a concern that starkly divides along partisan lines, according to a new ABC News/Ipsos released Friday. In the new poll, conducted by Ipsos in partnership with ABC News using Ipsos’ Knowledge Panel, nearly two-thirds of Americans said they more closely align with the view that opening the county now is not advantageous since it will result in a higher death toll, while slightly more than one-third agree with the belief that an immediate reopening is beneficial to minimize the negative impact on the economy. But those attitudes show deep partisan divisio




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Two Turkish clubs banned from UEFA competitions

038 - Romanian club handed deferred sanction




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UEFA Appeals Body bans two Turkish clubs from UEFA competitions

042 - Decisions made after Beşiktaş JK and Fenerbahçe SK appeal initial decision




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Parliament Committee to hear from leading microbiologist on the impact of COVID-19

A Scottish Parliament Committee will take evidence from a leading microbiologist, Professor Hugh Pennington, as it begins its scrutiny of the Government’s response to COVID-19.




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Fin24.com | Investors switch from SA to Mexico

The SA market is losing favour among international investors.




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Fin24.com | Sorting the 'p' from the 'e'

The price earnings ratio can be useful but sometimes misleading for investors trying to decide which equities to buy.




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From South Africa to Turkey to France

Martin and Petro De Lange start ministry to Turks in France.




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From dream to reality

“It was a long, green boat, sailing gently along the river,” recalled Ana Barros (Portugal), as she described her dream to her mum. This happened before she had even seen a picture of OM's Riverboat.




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What is Curriculum? From Managed Instruction to Personalized Learning

In this blended, mix-and-match, do-it-yourself world of education, what is curriculum, and who develops it? How do we know if it works?




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Direct from TXL to the Danish Sunny Island

From the 2nd July 2020, the Danish airline DAT will fly directly from Berlin-Tegel to Rønne (Bornholm). The popular Baltic island can then be reached within an hour’s flight time on Thursdays and Sundays until the 9th August.




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5 From 1: Federal Politics and Policy

My top five announcements from each monthly issue of School Improvement Industry Announcements – Policy and Politics. The criterion for selection is information and events that help edbizbuzz readers understand how what happens in Washington shapes our emerging market for school improvement products




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Who went through from the #UYL groups?

Ajax, Atlético, Barcelona, Hoffenheim, Liverpool, Manchester United, Porto and Real Madrid topped their groups to reach the last 16.