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Therapy and Psychotropic Medication Use in Young Children With Autism Spectrum Disorder

BACKGROUND AND OBJECTIVES:

Guidelines suggest young children with autism spectrum disorder (ASD) receive intensive nonpharmacologic interventions. Additionally, associated symptoms may be treated with psychotropic medications. Actual intervention use by young children has not been well characterized. Our aim in this study was to describe interventions received by young children (3–6 years old) with ASD. The association with sociodemographic factors was also explored.

METHODS:

Data were analyzed from the Autism Speaks Autism Treatment Network (AS-ATN), a research registry of children with ASD from 17 sites in the United States and Canada. AS-ATN participants receive a diagnostic evaluation and treatment recommendations. Parents report intervention use at follow-up visits. At follow-up, 805 participants had data available about therapies received, and 613 had data available about medications received.

RESULTS:

The median total hours per week of therapy was 5.5 hours (interquartile range 2.0–15.0), and only 33.4% of participants were reported to be getting behaviorally based therapies. A univariate analysis and a multiple regression model predicting total therapy time showed that a diagnosis of ASD before enrollment in the AS-ATN was a significant predictor. Additionally, 16.3% of participants were on ≥1 psychotropic medication. A univariate analysis and a multiple logistic model predicting psychotropic medication use showed site region as a significant predictor.

CONCLUSIONS:

Relatively few young children with ASD are receiving behavioral therapies or total therapy hours at the recommended intensity. There is regional variability in psychotropic medication use. Further research is needed to improve access to evidence-based treatments for young children with ASD.




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Screening Tools for Autism Spectrum Disorder in Primary Care: A Systematic Evidence Review

CONTEXT:

Recommendations conflict regarding universal application of formal screening instruments in primary care (PC) and PC-like settings for autism spectrum disorder (ASD).

OBJECTIVES:

We systematically reviewed evidence for universal screening of children for ASD in PC.

DATA SOURCES:

We searched Medline, PsychInfo, Educational Resources Informational Clearinghouse, and Cumulative Index of Nursing and Allied Health Literature.

STUDY SELECTION:

We included studies in which researchers report psychometric properties of screening tools in unselected populations across PC and PC-like settings.

DATA EXTRACTION:

At least 2 authors reviewed each study, extracted data, checked accuracy, and assigned quality ratings using predefined criteria.

RESULTS:

We found evidence for moderate to high positive predictive values for ASD screening tools to identify children aged 16 to 40 months and 1 study for ≥48 months in PC and PC-like settings. Limited evidence evaluating sensitivity, specificity, and negative predictive value of instruments was available. No studies directly evaluated the impact of screening on treatment or harm.

LIMITATIONS:

Potential limitations include publication bias, selective reporting within studies, and a constrained search.

CONCLUSIONS:

ASD screening tools can be used to accurately identify percentages of unselected populations of young children for ASD in PC and PC-like settings. The scope of challenges associated with establishing direct linkage suggests that clinical and policy groups will likely continue to guide screening practices. ASD is a common neurodevelopmental disorder associated with significant life span costs.1,2 Growing evidence supports functional gains and improved outcomes for young children receiving intensive intervention, so early identification on a population level is a pressing public health challenge.3,4




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Disparities in Service Use Among Children With Autism: A Systematic Review

CONTEXT:

Research reveals racial, ethnic, and socioeconomic disparities in autism diagnosis; there is limited information on potential disparities related to other dimensions of services.

OBJECTIVE:

We reviewed evidence related to disparities in service use, intervention effectiveness, and quality of care provided to children with autism by race, ethnicity, and/or socioeconomic status.

DATA SOURCES:

Medline, PsychInfo, Educational Resources Informational Clearinghouse, and the Cumulative Index to Nursing and Allied Health Literature were searched by using a combination of Medical Subject Headings terms and keywords related to autism, disparities, treatment, and services.

STUDY SELECTION:

Included studies addressed at least one key question and met eligibility criteria.

DATA EXTRACTION:

Two authors reviewed the titles and abstracts of articles and reviewed the full text of potentially relevant articles. Authors extracted information from articles that were deemed appropriate.

RESULTS:

Treatment disparities exist for access to care, referral frequency, number of service hours, and proportion of unmet service needs. Evidence revealed that racial and ethnic minority groups and children from low-income families have less access to acute care, specialized services, educational services, and community services compared with higher-income and white families. We found no studies in which differences in intervention effectiveness were examined. Several studies revealed disparities such that African American and Hispanic families and those from low-income households reported lower quality of care.

LIMITATIONS:

The body of literature on this topic is small; hence it served as a limitation to this review.

CONCLUSIONS:

The documented disparities in access and quality of care may further identify groups in need of outreach, care coordination, and/or other interventions.




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Chronic Thrombocytopenia as the Initial Manifestation of STIM1-Related Disorders

Pediatric thrombocytopenia has a wide differential diagnosis, and recently, genetic testing to identify its etiology has become more common. We present a case of a 16-year-old boy with a history of chronic moderate thrombocytopenia, who later developed constitutional symptoms and bilateral hand edema with cold exposure. Laboratory evaluation revealed evidence both of inflammation and elevated muscle enzymes. These abnormalities persisted over months. His thrombocytopenia was determined to be immune mediated. Imaging revealed lymphadenopathy and asplenia, and a muscle biopsy was consistent with tubular aggregate myopathy. Ophthalmology evaluation noted photosensitivity, pupillary miosis, and iris hypoplasia. Genetic testing demonstrated a pathogenic variant in STIM1 consistent with autosomal dominant Stormorken syndrome. Our case is novel because of the overlap of phenotypes ascribed to both gain-of-function and loss-of-function pathogenic variants in STIM1, thereby blurring the distinctions between these previously described syndromes. Pediatricians should consider checking muscle enzymes when patients present with thrombocytopenia and arthralgia, myalgia, and/or muscle weakness. Our case highlights the importance of both multidisciplinary care and genetic testing in cases of chronic unexplained thrombocytopenia. By understanding the underlying genetic mechanism to a patient’s thrombocytopenia, providers are better equipped to make more precise medical management recommendations.




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Sleep Disorders in Adolescents

Chronic sleep deprivation is a common, treatable condition among adolescents. Growing literature supports a myriad consequences that impact overall health, behavior, mood, and academic performance in this vulnerable age group during a time when there are rapid changes in physical development and emotional regulation. This article reviews the epidemiology and health effects of sleep deprivation in adolescents as well as common disorders leading to sleep loss and evidence to support treatment. Although a variety of important sleep disorders may disrupt quality of sleep in adolescents, such as obstructive sleep apnea, restless leg syndrome, and narcolepsy, this article will focus on common disorders that affect the quantity of sleep, such as poor sleep hygiene, circadian rhythm disorders, and insomnia.




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Management of Opioid Misuse and Opioid Use Disorders Among Youth

In response to the growing impact of the current opioid public health crisis in the United States on adolescents and young adults, pediatricians have an expanding role in identifying opioid use early, preventing escalation of risky use, reducing opioid-related harms, and delivering effective therapies. Research and expert consensus suggest the use of brief interventions focused on reducing risks associated with ongoing opioid use and using motivational interviewing strategies to engage youth in treatment. Because fatal opioid overdose remains a major cause of opioid-related mortality among youth, delivering overdose education as part of any visit in which a youth endorses opioid use is one evidence-based strategy to decrease the burden of opioid-related mortality. For youth that are injecting opioids, safe injection practices and linkage to needle or syringe exchanges should be considered to reduce complications from injection drug use. It is crucial that youth be offered treatment at the time of diagnosis of an opioid use disorder (OUD), including medications, behavioral interventions, and/or referral to mutual support groups. The 2 medications commonly used for office-based OUD treatment in adolescents are extended-release naltrexone (opioid antagonist) and buprenorphine (partial opioid agonist), although there is a significant treatment gap in prescribing these medications to youth, especially adolescents <18 years of age. Addiction is a pediatric disease that pediatricians and adolescent medicine physicians are uniquely poised to manage, given their expertise in longitudinal, preventive, and family- and patient-centered care. Growing evidence supports the need for integration of OUD treatment into primary care.




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Sport & discipleship - Igor's story

Sport creates a platform for evangelism and discipleship in Ukraine.




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Leonard Cheshire Disability host Fashion Show in Glasgow

Words: Abbie Lyall




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Issue of the Day: Disney's new TV streaming service

Disney, one of the most famous names in film, has launched a new TV service, called Disney Plus. Coming to a living room near you.




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Distributing Bibles at the Reindeer Festival

Partners of OM EAST distribute copies of My First Bible to Nenets children on the Yamal Peninsula in northern Arctic Russia.




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Swindon's Swedish adventure

We follow Swindon Town Football in the Community Under-17 girls on their journey from England to the Gothia Cup in Sweden.




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Finland's grassroots paradise

We visit the winners of the Best Club category in the 2011 UEFA Grassroots Day Awards.




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Passenger terminal at BER approved for use / Dahme-Spreewald administrative district grants approval

The Dahme-Spreewald administrative district’s local building inspection authority confirmed the completion of the passenger terminal (Terminal 1) at BER following completion of the construction work.




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Coronavirus: Scottish businesses which ignore social distancing face police action

NICOLA Sturgeon said she does not expect police to be “routinely patrolling office blocks” as sweeping new enforcement powers come into force to include workplaces flouting social distancing rules.




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TV: Grime artist Big Zuu prepares made-to-order dishes for UK comedians

Big Zuu is headed back out on tour - but not as we know it.




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Rosemary Goring's Country Life: finding distraction and delight, right outside the window

Sunday, April 19, 2020.




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Gardening: Discover the best virtual gardens, podcasts and expert advice

If you're yearning for all the gardening shows that have been cancelled, you can still be inspired by exploring gorgeous virtual gardens now and throughout the summer, from the comfort of your armchair.




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Developing disciples

OM intentionally disciples Cambodian staff so that they, in turn, can disciple others.




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Pioneering disability tech firm Neatebox accepted into bank accelerator programme

NEATEBOX, the Scottish technology firm which specialises in improving accessibility for people with disabilities, has been accepted into an accelerator programme run by Royal Bank of Scotland.




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Glasgow man arrested after 'stun guns' discovered in firearm smuggling probe

A 53-year-old man has been arrested in connection with smuggling firearms into the country.




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Vanishing places: Scottish locations that have disappeared

St Kilda




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Coronavirus in Scotland: Pop-up paths and cycle lanes to boost social distancing

TEMPORARY walking and cycling routes are set to pop-up across Scotland in a bid to improve social distancing while Scots are now being advised to wear face coverings in “enclosed spaces”.




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'Completely different take on Indian food' – Ron Mackenna's restaurant review of Swadish

Swadish – Modern Indian Cuisine




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Latest 11-Inch iPad Pro With Cellular Gets $199 Discount

The latest iPad Pro featuring 1TB of storage and cellular connectivity is on sale at Amazon for just $1,299.99. Models with less storage and just Wi-Fi are also marked down.




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Gerard Richardson: South African surprise led to discovery

ONE of the trying things about being a drinks columnist is the number of wines I have to taste in order to write this Shakespearian text for you guys. Products have to be really special to stand out from the crowd and, thankfully, they occasionally still do.




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Iain Macwhirter: Super Tuesday will showcase Democrats' dismal failure to take on Donald Trump

Mardi Gras in New Orleans has always had a gothic element. The voodoo culture dates from the African American diaspora, though it’s now mostly for tourists. But this year there was an authentically macabre dimension to Fat Tuesday.




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Rapid Deployment of Remote Learning: Lessons From 4 Districts

Chief technology officers are facing an unprecedented test of digital preparedness due to the coronavirus pandemic, struggling with shortfalls of available learning devices and huge Wi-Fi access challenges.




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Many Districts Won't Be Ready for Remote Learning If Coronavirus Closes Schools

E-learning may help some schools keep instruction flowing but major gaps in access and resources mean not all schools are ready to offer virtual classes, and not all students are equipped to learn online.




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How Districts Are Helping Teachers Get Better at Tech Under Coronavirus

Educators are struggling to learn how to use new tech tools—devices, apps, software, and online textbooks—in greater volume than ever before.




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How Weather Forced a Minn. District to Establish E-Learning Options On the Fly

The director of teaching and learning for a Minnesota district talks about putting e-learning days into action under difficult circumstances.




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Remote Learning Problems During Coronavirus Prompt Resignation of Big District Tech Leader

The top technology official for Virginia's Fairfax County schools resigned after the district struggled to handle some major technical glitches in its e-learning platforms.




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Coronavirus: Social distancing to continue in schools when they gradually reopen

EDUCATION Secretary John Swinney does not expect schools to reopen overnight as he stressed they would only do so when it was safe for public health.




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Neil Mackay: Scotland’s handling of schools in lockdown is a national disgrace

THE teacher had four pupils yesterday. Just four pupils out of a class of 33 took part in virtual online lockdown lessons.




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How One District Is Raising Math Rigor and Achievement for Students of Color

The Long Beach, Calif., school district is deploying a multifaceted strategy to put more students of color in high-level math courses and help them succeed.




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Black Parents Force District to End Academic Tracking

Fed up with their district’s unmet pledges to stop steering African American students into low-level classes, parents take action.




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Why Do Schools Hang On to Discriminatory Dress Codes?

School dress codes are clashing with students, parents, and researchers who see the rules and their enforcement as rife with racism and sexism. Some school leaders say the codes are important for safety and teaching kids to comply.




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SNP MP accused of capitalising on virus crisis following 'brazenly disloyal' remarks at virtual meeting

AN SNP MP has been accused of capitalising on the virus crisis to undermine Nicola Sturgeon and boost their own profile following a series of remarks made in an online party meeting.




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Ed. Dept. Says States Must Update Teacher-Distribution Plans

The Education Department wants states to re-submit "equity plans" to ensure that effective teachers are matched with disadvantaged and minority students.




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Flexible Seating: Collaboration Catalyst or Classroom Disaster?

Popularized by social media, new classroom arrangements are all the rage in K-12. But experts and educators caution there is more to it than just moving desks around.




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Loving Our Students From a Distance

During this hard and scary time, when our students need their teachers the most, suddenly they can’t be there in person. Here are some ways teacher Justin Minkel has found to keep that connection virtually.




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Wealthier Enclaves Breaking Away From School Districts

Over two years, 27 communities have split from their home districts, and the new districts are mostly wealthier, whiter, and more property-rich than the ones left behind.




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In Alabama Case, Desegregation History Defeats District's Secession Effort

The appeals court put the brakes on a predominantly white community's racially tinged efforts to secede from a larger school system.




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Schools' Racial Makeup Can Sway Disability Diagnoses

Three new studies show that a web of factors appear to influence how often black and Hispanic children are identified for special education compared to similar white peers.




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The Splintering of Wealthy Areas From School Districts Is Speeding Up

The school funding group EdBuild finds neighborhood attempts to secede popping up in more school districts, with racial and economic isolation increasing in their wake.




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No race balance, but desegregation ends for Georgia district




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Desegregation Order Lifted on Georgia School District in Coronavirus Hotspot

Dougherty County, a largely black school district in an region heavily affected by coronavirus, is no longer subject to desegregation orders first imposed in 1963.




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District's Hair-Length Rule for Male Basketball Players Struck Down by Court

A federal appeals court has struck down an Indiana school district's policy requiring short hair for boys on the basketball team, ruling that the lack of a similar policy for girls'-team basketball players results in illegal sex discrimination.




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Judge Dismisses Concussion Lawsuit Against Illinois High School Association

An Illinois judge has dismissed the nation's first class-action lawsuit against a state high school association over its handling of concussions, ruling that it had made strides in that regard since the filing of the lawsuit.




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Parents Sue N.Y. School Districts, Medical Responders Over Football Player's Death

The parents of a 16-year-old who died last fall from football-related brain trauma are suing the New York school districts he played for and the medical responders who tended to him the night he sustained his fatal injury.




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How's Discipline at Your School? Don't Just Look at Referral and Suspension Data, Get Perception Data

YouthTruth asked 104,000 school staff, students, and their families how they perceive the fairness of discipline at their schools. The results can help start conversations about discipline policy and leading by listening.