Title: Working With Horses May Ease Stress in Kids
Category: Health News
Created: 4/29/2014 2:36:00 PM
Last Editorial Review: 4/30/2014 12:00:00 AM

North Carolina is developing a unique and innovative infrastructure to support integrated physical, behavioral, and social health care. Efforts by the North Carolina Department of Health and Human Services, the Foundation for Health Leadership & Innovation, Cone Health, Atrium Health, and the One Charlotte Health Alliance advance our understanding of how to best operationalize the design and payment of integrated services. Best practices such as the collaborative care and primary care behavioral health models reduce inefficiencies and disparities by bringing together teams of primary care and behavioral health care providers.

As the novel coronavirus spreads, communities across the United States are struggling to offer public testing. The need is urgent. Testing got off to a delayed start in the United States as a result of technical missteps and a slow response from government officials. Now cities across the country are...

Cytogenetic risk stratification at diagnosis has long been one of the most useful tools to assess prognosis in acute lymphoblastic leukemia (ALL). To examine the prognostic impact of cytogenetic abnormalities on outcomes after allogeneic hematopoietic cell transplantation, we studied 1731 adults with Philadelphia-negative ALL in complete remission who underwent myeloablative or reduced intensity/non-myeloablative conditioning transplant from unrelated or matched sibling donors reported to the Center for International Blood and Marrow Transplant Research. A total of 632 patients had abnormal conventional metaphase cytogenetics. The leukemia-free survival and overall survival rates at 5 years after transplantation in patients with abnormal cytogenetics were 40% and 42%, respectively, which were similar to those in patients with a normal karyotype. Of the previously established cytogenetic risk classifications, modified Medical Research Council-Eastern Cooperative Oncology Group score was the only independent prognosticator of leukemia-free survival (P=0.03). In the multivariable analysis, monosomy 7 predicted post-transplant relapse [hazard ratio (HR)=2.11; 95% confidence interval (95% CI): 1.04-4.27] and treatment failure (HR=1.97; 95% CI: 1.20-3.24). Complex karyotype was prognostic for relapse (HR=1.69; 95% CI: 1.06-2.69), whereas t(8;14) predicted treatment failure (HR=2.85; 95% CI: 1.35-6.02) and overall mortality (HR=3.03; 95% CI: 1.44-6.41). This large study suggested a novel transplant-specific cytogenetic scheme with adverse [monosomy 7, complex karyotype, del(7q), t(8;14), t(11;19), del(11q), tetraploidy/near triploidy], intermediate (normal karyotype and all other abnormalities), and favorable (high hyperdiploidy) risks to prognosticate leukemia-free survival (P=0.02). Although some previously established high-risk Philadelphia-negative cytogenetic abnormalities in ALL can be overcome by transplantation, monosomy 7, complex karyotype, and t(8;14) continue to pose significant risks and yield inferior outcomes.

This follow-up study of a randomized, prospective trial included 192 patients with newly diagnosed severe aplastic anemia receiving antithymoglobulin and cyclosporine, with or without granulocyte colony-stimulating factor (G-CSF). We aimed to evaluate the long-term effect of G-CSF on overall survival, event-free survival, probability of secondary myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML), clinical paroxysmal nocturnal hemoglobinuria, relapse, avascular osteonecrosis and chronic kidney disease. The median follow-up was 11.7 years (95% CI, 10.9-12.5). The overall survival rate at 15 years was 57±12% in the group given G-CSF and 63±12% in the group not given G-CSF (P=0.92); the corresponding event-free survival rates were 24±10% and 23±10%, respectively (P=0.36). In total, 9 patients developed MDS or AML, 10 only a clonal cytogenetic abnormality, 7 a solid cancer, 18 clinical paroxysmal nocturnal hemoglobinuria, 8 osteonecrosis, and 12 chronic kidney disease, without any difference between patients treated with or without G-CSF. The cumulative incidence of MDS, AML or isolated cytogenetic abnormality at 15 years was 8.5±3% for the G-CSF group and 8.2±3% for the non-G-CSF group (P=0.90). The cumulative incidence of any late event including myelodysplastic syndrome or acute myeloid leukemia, isolated cytogenetic abnormalities, solid cancer, clinical paroxysmal nocturnal hemoglobinuria, aseptic osteonecrosis, chronic kidney disease and relapse was 50±12% for the G-CSF group and 49±12% for the non-G-CSF group (P=0.65). Our results demonstrate that it is unlikely that G-CSF has an impact on the outcome of severe aplastic anemia; nevertheless, very late events are common and eventually affect the prognosis of these patients, irrespectively of their age at the time of immunosuppressive therapy (NCT01163942).

The low supply of traditional office space expanding in central districts of Ho Chi Minh City (HCMC) has lead to the growth of coworking spaces, or flexible office spaces there.

When his alarm goes off at 3:30 a.m., 54-year-old Jeff Reid knows it's time to begin his day and prepare for an eight-hour shift on the front lines of the coronavirus pandemic. As a grocery store worker, Reid never imagined he'd find himself in this position. Every day before his 5 a.m. shift, Reid prepares his morning essentials -- 1,000 milligrams of the powdered vitamin supplement Emergen-C and his morning prayers.

From yoga apps to an intelligent jumprope

Azure's still going strong, and even Xbox avoided major losses.

Follow our live Covid-19 updates HERE Coronavirus: The symptoms

Follow our live coronavirus updates here Coronavirus: the symptoms

An NHS nurse who continued to work night shifts into her 80s has died after contracting Covid-19, her devastated family have confirmed.

Chancellor Rishi Sunak said the Government had faced some unexpected delays to the delivery of personal protective equipment from Turkey.

A top New York City doctor has taken her own life after battling coronavirus on the frontline, officials have said.

In today's Diary: Jude Kelly leads review of coronavirus impact on women in arts / Sophie Raworth's blue moment / Kerry Godliman struggles with tech / Philip Tetlock on Dominic Cummings and his reputation

Measures being considered to help safely reopen workplaces included staggered shift times and reduced hot-desking, according to a draft Government plan.

A security guard has denied raping a woman while working at an NHS hospital.

NASA Administrator Jim Bridenstine has confirmed in a tweet that the space agency is working with movie star Tom Cruise on a project that involves shooting a film on the International Space Station. Deadline Hollywood reported on Monday that a space movie project involving NASA and SpaceX is in the works, but that "no studio is in the mix at this stage." Bridenstine followed up with a tweet saying that NASA was "excited" to be working with Cruise, and explaining that "we need popular media to inspire a new generation of engineers and scientists to make NASA's ambitious plans a… Read More

The US believes Russia is working with Syrian President, Bashar al-Assad, to send militia fighters and equipment to Libya, according to senior officials. Speaking to reporters on Thursday, US special envoy for Syria, Jim Jeffrey, said Libya’s increasingly shadowy battlefield could get even more complicated. “We know that, certainly, the Russians are working with Assad to transfer militia fighters, possibly third country, possibly Syrian, to Libya, as well as equipment,” he said. His comments came a day after a leaked UN report confirmed the presence of Russian and Syrian mercenaries operating in Libya in support of renegade military commander, Khalifa Haftar. The report revealed that Russian private military contractor, Wagner Group, has up to 1,200 mercenaries operating in Libya in support of General Haftar’s forces, which are already backed by the UAE, Russia and Egypt. The report, seen by Reuters, is one of the first indications of the scale of Wagner’s military operation in Libya’s messy battlefield, as well as the first time the UN has confirmed the presence of the shadowy Russian mercenaries. Since 2014, the oil-rich North African country has been split between areas controlled by the internationally recognised Government of National Accord in Tripoli and the northwest, and territory held by Gen Haftar’s eastern-based forces in Benghazi. For almost six years Gen Haftar’s forces have been at war with a coalition of militias from the west of the country who support the government in Tripoli. Turkey is the only military backer of the Tripoli government that is currently trying to stave off Haftar’s year-long offensive on the capital. The UAE and Egypt have long strengthened Haftar’s forces with military equipment, including aircraft and helicopters, while Moscow provided private contractor forces. As the conflict has drawn on and involvement has increasingly become the stage for a struggle for power in the region, diplomats say both Turkey and the UAE have deployed drones and the use of mercenaries has increased, now seemingly including forces from Russia and Syria. Libya has been mired in chaos since a 2011 NATO intervention helped topple Colonel Muammar Gaddafi, and its battlefields increasingly populated with foreign fighters in a shadow-war. Russian mercenaries were first reported fighting alongside General Haftar’s forces in Libya in 2018. Vladimir Putin, the Russian president, however, insisted that those mercenaries do not represent the Russian government. Yet when General Haftar visited Moscow in 2018, Yevgeny Prigozhin, a businessman with long-standing ties to Mr Putin and suspected owner of Wagner, was seen in the footage of the meeting, sitting near the Russian defence minister. Russia, which also backs Assad’s government in Syria, has maintained a delicate balancing act in Libya, forging ties with both the UN-recognised government and with the rebel commander. But Moscow’s patience with General Haftar began to run out earlier this year when he and his entourage in January abruptly left the much-anticipated cease-fire talks in Moscow mediated by Russia and Turkey without signing the deal. Henry Wooster, deputy assistant secretary at State Department’s Bureau of Near Eastern Affairs also expressed increasing concern over the ties between the Libyan commander and Syria’s president, who are both bitter enemies of Turkey and fighting Turkish-backed militant groups on their soil. “Haftar’s establishment of so-called diplomatic relations with the Assad regime...is very much a part of the piece of the question of Syrian mercenaries, at least on his side of the equation,” he said. While the leaked report also confirmed the presence of Syrian mercenaries in Libya fighting alongside Haftar’s forces, Pro-Turkish Syrians are also known to be fighting with the Tripoli government, against General Haftar.

Thanks to them, everyone from Vancouver immigrants to Langley labourers are staying well fed and cared for. 

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The remote working stakes have just gone up a notch

Report suggests the series takes place in a whole new part of the Star Wars timeline

'One foot wrong and you don't know what could happen'

Work up a sweat while protecting your locks

Manchester United are yet to offer Odion Ighalo a permanent deal with Ole Gunnar Solskjaer undecided over his plans to sign a striker this summer.

Manchester United fans hailed the fine work of 'agent Marcus Rashford' once more after his FIFA 20 battle with England colleague Jadon Sancho.

West Ham's medical department have relished the challenge of keeping the squad fit and motivated during the lockdown and has hailed the commitment of the players.

Bees vice-chairman Donald Kerr believes there is scope for the trusts of all London clubs to unite at this difficult time

The pandemic reminds me of a different invisible enemy. Once again, coordinated action is the only effective response

Deja vu. In recent days I’ve had that sense more than once. Every time I come home, remove my mask and wash my hands, I start thinking whether it is safe to keep on wearing the clothes that I had on outside. What if they are contaminated by the virus? Well, I can change clothes, but what if the particles have already jumped somewhere else, and are now in my home? Some would call it paranoia. I call it deja vu. I recognise those thoughts and remember the feelings.

That is because I first experienced them more than 30 years ago, in May 1986, on a trip to Kyiv, then the capital of Soviet Ukraine. It was a few weeks after the explosion at the Chernobyl nuclear reactor, and I was in the city – about 100km from the disaster area – on a business trip. We already knew that there was radiation in the air. Water trucks were spraying the streets, foreign students were leaving the city, and overseas broadcasters like the BBC were telling us to stay inside. But our own government was sending confusing and distressing messages: there is absolutely no danger, but make sure you keep children inside, and pregnant women too. Oh, and close your windows when you are at home.

In celebration of Mother’s Day, Women in Animation and the Animation Guild have joined forces to encourage equality and flexibility in the workplace and to support the animation community “as it navigates the unprecedented effects of the COVID-19 pandemic.” In a joint statement, they noted that “many animation workers are pulling double duty – balancing […]

With food, water and money in desperately short supply, dozens of working dogs have been surrendered from properties throughout Queensland and New South Wales.

Two-thirds of working mums and dads are struggling to look after themselves physically and mentally, according to a new report. The findings are pretty depressing. But what can parents actually do about it?

A rare, insider look at the highly secretive game industry from the Game Developers Conference. Developers share thoughts on working conditions, the need for unionization, attempts to diversify and more.

Workers at Amazon's massive Riverside County fulfillment center in Eastvale, where there have been three confirmed cases of COVID-19, filed complaints with Cal/OSHA and the Riverside Department of Public Health on Wednesday

Jobless international hospitality workers deemed ineligible for the Federal Government's JobKeeper and JobSeeker programs are "heartbroken" at their treatment and turning to restaurants providing free meals during the coronavirus pandemic.

The former first lady returned to her alma mater, Chicago’s Whitney M. Young Magnet High School, in November 2018 as part of her cross-country tour to promote her “Becoming” memoir, hosting an intimate discussion with 20 female students.

Veteran character actor Peter Gerety has a meaty role in Richard Jury's "Working Man" even as the movie shifts from quiet dignity into melodrama.

"Every professional faces challenges. As a woman in industry, particularly in leadership, it adds another dimension to those challenges in how you present yourself."

The United States has filed a lawsuit against New York attorney Thomas B. Pruzan, d/b/a the Pruzan Law Firm, seeking to put an end to Mr. Pruzan’s repeated failure to timely deposit and pay the employment and unemployment taxes due from his law firm, as well as his failure to timely file employment and unemployment tax returns with the Internal Revenue Service.

"Justice is, quite simply, the cornerstone of American democracy. The most profound aspirations of our nation’s founding could not be satisfied, nor its audacious hopes realized, without meaningful access to justice for all."

Attorney General Eric Holder today announced the formation of a Financial Fraud Enforcement Task Force Working Group to focus specifically on fraud in the energy markets.

Chun-Yu Zhao, of Centreville, Va., and Donald H. Cone, of Frederick, Md., were convicted by a federal jury in Alexandria, Va., for their roles in a sophisticated scheme to import and sell counterfeit Cisco-branded computer networking equipment.

Donald H. Cone, 48, of Frederick, Md., was sentenced today in Alexandria, Va., to 30 months in prison for his role in a sophisticated conspiracy to import and sell counterfeit Cisco-branded computer networking equipment.

A Virginia woman was sentenced today to 60 months in prison for leading a sophisticated conspiracy to import and to sell counterfeit Cisco-branded computer networking equipment, laundering criminal proceeds and obtaining her citizenship through fraud.