A previous work by the artist, dedicated to the Israeli victims of Hamas, was also vandalized.

Trump also said he will nominate Fox News Channel host Pete Hegseth to be secretary of defense.

1. Donald Trump picks Elon Musk, Vivek Ramaswamy to lead Government Efficiency Department  Moneycontrol
2. Trump’s 'Manhattan Project' of government reform: Musk and Ramaswamy to lead efficiency crusade  The Times of India
3. Donald Trump Picks Elon Musk, Vivek Ramaswamy For Cabinet: Internet Has This To Say  News18
4. A dope for DOGE (and Dogecoin): Trump taps Musk in efficiency team, crypto fans rejoice  The Economic Times
5. Video | Elon Musk In Trump's New Cabinet, UK Church Abuse Scandal, Saudi Megacity in Trouble  NDTV

Spain's Climate Floods Tragedy in Pictures

President-elect Donald Trump is starting to fill key posts in his second administration.

to wire guitar pickups

A mouse's tumours, scales from a butterfly's wings and a smiling cross-section of a bracken fern are some of the incredible images from the Nikon Small World photography competition

Working with a tiny cantilever, physicists managed to violate the second law of thermodynamics, using less energy than expected to change the cantilever’s motion

This spectacular selection of images is taken from the winners of the Northern Lights Photographer of the Year competition, run by Capture the Atlas

Amazing images of an open-air library, underground lab and design museum show the reincarnation of dead mines, captured in a new book, 102 Things to Do With a Hole in the Ground

The Renaissance artist Michelangelo had carried out human dissections, which may have led him to include women with breast cancer in some of his pieces

A new radiometric dating technique reveals that cave paintings on Sulawesi, Indonesia, are even older than previously thought, pushing back the earliest evidence of storytelling

We know that modern humans took one of two routes to first reach Australia, and now an ancient chunk of plant resin has tipped the evidence towards the northern option

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Title: Think Safety When Picking, Packing School Backpacks
Category: Health News
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Category: Health News
Created: 8/26/2020 12:00:00 AM
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Category: Health News
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Title: Picture of Nickel Contact Dermatitis
Category: Images
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Title: Picture of Phototoxic Dermatitides
Category: Images
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Pleiotropy, measured as expression breadth across tissues, is one of the best predictors for protein sequence and expression conservation. In this study, we investigated its effect on the evolution of cis-regulatory elements (CREs). To this end, we carefully reanalyzed the Epigenomics Roadmap data for nine fetal tissues, assigning a measure of pleiotropic degree to nearly half a million CREs. To assess the functional conservation of CREs, we generated ATAC-seq and RNA-seq data from humans and macaques. We found that more pleiotropic CREs exhibit greater conservation in accessibility, and the mRNA expression levels of the associated genes are more conserved. This trend of higher conservation for higher degrees of pleiotropy persists when analyzing the transcription factor binding repertoire. In contrast, simple DNA sequence conservation of orthologous sites between species tends to be even lower for pleiotropic CREs than for species-specific CREs. Combining various lines of evidence, we propose that the lack of sequence conservation in functionally conserved pleiotropic CREs is owing to within-element compensatory evolution. In summary, our findings suggest that pleiotropy is also a good predictor for the functional conservation of CREs, even though this is not reflected in the sequence conservation of pleiotropic CREs.

The human major histocompatibility complex (MHC) is a ~4 Mb genomic segment on Chromosome 6 that plays a pivotal role in the immune response. Despite its importance in various traits and diseases, its complex nature makes it challenging to accurately characterize on a routine basis. We present a novel approach allowing targeted sequencing and de novo haplotypic assembly of the MHC region in heterozygous samples, using long-read sequencing technologies. Our approach is validated using two reference samples, two family trios, and an African-American sample. We achieved excellent coverage (96.6%–99.9% with at least 30x depth) and high accuracy (99.89%–99.99%) for the different haplotypes. This methodology offers a reliable and cost-effective method for sequencing and fully characterizing the MHC without the need for whole-genome sequencing, facilitating broader studies on this important genomic segment and having significant implications in immunology, genetics, and medicine.

Anna Marie Privitere gets de-wormed but has to tell Chris to stop helping. Phil Willis is not at all biased about musous. Kelley Ryan is all about the DMCAs. But Alex Fuller saw all of this coming.

The post RPG Cast – Episode 566: “Unsolicited Dik-Dik Pics” appeared first on RPGamer.

Phil laughs at stupid Diablo IV hardcore deaths. Kelley goes for the all cannon ending. Jason is depressed and wants to play Dirge of Cerberus. Ryan doesn't have enough turn based RPGs in his life. Also, happy 100th birthday to Paw's grandfather!

The post RPG Cast – Episode 680: “Warning: Spicy Sausage” appeared first on RPGamer.

Robert wants to be Tuxedo Mask, but with food and goggles. Kelley plays Find the Smell every day. Chris longs for freedom from his loot torture.

The post RPG Cast – Episode 707: “Pictomancers Working for Exposure” appeared first on RPGamer.

The Real Housewives of Salt Lake City is TV’s best soap opera, week after week offering twists more shocking than secret twins and characters returning from the dead. That’s because it’s all real, happening in the most haunted suburb in the continental United States.

Where else do two women connect over knowing the long-lost birth father of one’s child? Is there another city where women squabble over body positivity in a parking lot off the side of a snowy mountain? Surely, there’s no other place on Earth where Lisa Barlow could come across anywhere near a voice of reason.

But that all happens here in Salt Lake City. Five episodes in, Season 5 has continued to evolve into the most captivating season in modern Real Housewives history, carried by the ever-changing bonds between our OGs and a team of wonderfully bizarre newbies.

Read more at The Daily Beast.

Senate Minority Leader Mitch McConnell called his party’s presidential nominee, Donald Trump, a “stupid,” “ill-tempered,” and “despicable human being,” according to his own records.

McConnell made the withering assessments in a series of private “personal oral histories” that he gave to Michael Tackett, the deputy Washington bureau chief of the Associated Press, who has a forthcoming biography about the Kentucky senator called The Price of Power. The AP conveniently reported the book’s juicy details.

McConnell’s remarks were made after the 2020 election that Trump lost, and the senator was apparently elated to see the backside of the former president, musing, “it’s not just the Democrats who are counting the days” until he leaves office.

Read more at The Daily Beast.

Update:

The RPS 100 is our list of the best games to play on PC. It encompasses the full breadth and width of PC gaming stretching back to 1873, but focuses solely on those games that remain great to play today. It's updated yearly by our crack team of writers, and the first half of the 2024 edition is live now.

Read more

Gears just a few micrometres wide can be carved from silicon using a beam of electrons, enabling tiny robots or machines that could interact with human cells

Fortnite fans are going wild after Epic Games announced it's bringing back the original version of its battle royale as Fortnite OG as a permanent addition to the game.

Senate Republicans on Wednesday will elect a new party leader for the first time in nearly two decades.

President-elect Donald Trump announced Tuesday that John Ratcliffe, a former Texas congressman and director of national intelligence, will serve as the director of the Central Intelligence Agency in his administration.

President-elect Donald Trump announced a flurry of appointments Tuesday for key posts in his new administration, including former Director of National Intelligence John Ratcliffe to lead the CIA and the expected nomination of South Dakota Gov. Kristi Noem to head the Department of Homeland Security.

Three people have been taken to hospital after a car mounted the pavement and smashed into a restaurant in Piccadilly Circus, the Metropolitan Police have said.

The Renaissance artist Michelangelo had carried out human dissections, which may have led him to include women with breast cancer in some of his pieces

President-elect Trump has made six selections to serve in his Cabinet in the week since the election, a faster pace than he set when elected to the presidency in 2016.

Despite his own isolationist musings, the first picks of President-elect Donald Trump's incoming administration hail from a decidedly more traditionalist wing of the Republican Party.

President-elect Trump announced that he had picked real estate investor and campaign donor Steve Witkoff to be his special envoy to the Middle East.

John Ratcliffe, who previously served as President-elect Trump's principal intelligence advisor, has now been picked by Trump to serve as director of the CIA.

Since winning the election last week, President-elect Trump has begun evaluating and rolling out his Cabinet picks, with dozens of names jockeying for some two dozen positions.

The Canadian women's soccer team was implicated in a drone scandal this past summer. But, an investigation determined drone use against opponents, predated the Paris Olympics.

Both hit weeks after OpenAI released a ChatGPT app.

Anthropic’s smallest AI model now beats its older largest LLM, Opus, at some tasks.