Development of the cerebellum from molecular aspects to diseases / Hassan Marzban, editor
The biology of thought: a neuronal mechanism in the generation of thought - a new molecular model / Krishnagopal Dharani
Sensation and perception / E. Bruce Goldstein and James R. Brockmole
The Oxford handbook of molecular psychology / edited by Turhan Canli
GABA and the basal ganglia: from molecules to systems / edited by James M. Tepper, Elizabeth D. Abercrombie and J. Paul Bolam
Genetic models and molecular pathways underlying autism spectrum disorders / edited by Anantha Shekhar
Melanin-concentrating hormone and sleep: molecular, functional and clinical aspects / S.R. Pandi-Perumal, Pablo Torterolo, Jaime M. Monti, editors
Chromatographic detection of low-molecular-mass metal complexes in the cytosol of Saccharomyces cerevisiae
DOI: 10.1039/C9MT00312F, Paper
Labile metal pools in the cytosol of yeast, including those of iron, copper, zinc, and manganese, can be detected and characterized using size-exclusion chromatography with online ICP-MS.
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Gold(III) bis(dithiolene) complexes: from molecular conductors to prospective anticancer, antimicrobial and antiplasmodial agents
DOI: 10.1039/D0MT00064G, Paper
The anticancer, antimicrobial and antiplasmodial activities of six gold(III) bis(dithiolene) complexes were studied. Complexes (1-6) showed relevant anticancer properties against A2780/A2780cisR ovarian cancer cells (IC50 values of 0.08-2 µM), also...
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[ASAP] The Energetics of Hydrogen Molecule Oxidation in NiFe-hydrogenase
Podcast: Treating cocaine addiction, mirror molecules in space, and new insight into autism
Listen to stories on the first mirror image molecule spotted in outer space, looking at the role of touch in the development of autism, and grafting on lab-built bones, with online news editor David Grimm. Karen Ersche talks about why cocaine addiction is so hard to treat and what we can learn by bringing addicted subjects into the lab with host Sarah Crespi. [Image: Science/Music: Jeffrey Cook]
Cargo-sorting molecular robots, humans as the ultimate fire starters, and molecular modeling with quantum computers
This week we hear stories on the gut microbiome’s involvement in multiple sclerosis, how wildfires start—hint: It’s almost always people—and a new record in quantum computing with Online News Editor David Grimm. Andrew Wagner talks to Lulu Qian about DNA-based robots that can carry and sort cargo. Sarah Crespi goes behind the scenes with Science’s Photography Managing Editor Bill Douthitt to learn about snapping this week’s cover photo of the world’s smallest neutrino detector. Listen to previous podcasts. [Image: Curtis Perry/Flickr; Music: Jeffrey Cook]
Following 1000 people for decades to learn about the interplay of health, environment, and temperament, and investigating why naked mole rats don’t seem to age
David Grimm—online news editor for Science—talks with Sarah Crespi about the chance a naked mole rat could die at any one moment. Surprisingly, the probability a naked mole rat will die does not go up as it gets older. Researchers are looking at the biology of these fascinating animals for clues to their seeming lack of aging. Sarah also interviews freelancer Douglas Starr about his feature story on the Dunedin Multidisciplinary Health and Development Study—a comprehensive study of the lives of all the babies born in 1 year in a New Zealand hospital. Starr talks about the many insights that have come out of this work—including new understandings of criminality, drug addiction, and mental illness—and the research to be done in the future as the 1000-person cohort begins to enter its fifth decade. Listen to previous podcasts. [Image: Tim Evanson/Flickr/CC BY-SA 2.0; Music: Jeffrey Cook]
How DNA is revealing Latin America’s lost histories, and how to make a molecule from just two atoms
Geneticists and anthropologists studying historical records and modern-day genomes are finding traces of previously unknown migrants to Latin America in the 16th and 17th centuries, when Asians, Africans, and Europeans first met indigenous Latin Americans. Sarah Crespi talks with contributing correspondent Lizzie Wade about what she learned on the topic at the American Association of Physical Anthropologists’s annual meeting in Austin. Sarah also interviews Kang-Keun Ni about her research using optical tweezers to bring two atoms—one cesium and one sodium—together into a single molecule. Such precise control of molecule formation is allowing new observations of these basic processes and is opening the door to creating new molecules for quantum computing. This week’s episode was edited by Podigy. Listen to previous podcasts. [Image: Juan Fernando Ibarra; Music: Jeffrey Cook]
Molecular analysis of edible bird’s nest and rapid authentication of Aerodramus fuciphagus from its subspecies by PCR-RFLP based on the cytb gene
DOI: 10.1039/C9AY02548K, Paper
Edible bird's nest (EBN), for its great nutritional value, is widely used around the world, especially in China and Singapore. EBNs of different origins and types may vary in price...
The content of this RSS Feed (c) The Royal Society of Chemistry
Improving the determination of celecoxib in body fluids and pharmaceuticals using a new selective and thermosensitive molecularly imprinted poly(vinylidene fluoride) membrane
DOI: 10.1039/D0AY00237B, Paper
Molecularly imprinted membranes that demonstrated high selectivity for celecoxib were synthesized using N-vinylcaprolactam and 2-hydroxyethyl methacrylate.
The content of this RSS Feed (c) The Royal Society of Chemistry
In situ imaging of intracellular human telomerase RNA with molecular beacon-functionalized gold nanoparticles
DOI: 10.1039/D0AY00461H, Paper
We develop molecular beacon-functionalized gold nanoparticles for in situ human telomerase RNA imaging in live cells.
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Sample treatment based on molecularly imprinted polymers for the analysis of veterinary drugs in food samples: a review
DOI: 10.1039/D0AY00533A, Critical Review
The use of veterinary drugs in medical treatments and in the livestock industry is a recurrent practice. In subtherapeutic doses during prolonged times act to growth promoters. Residues of these...
The content of this RSS Feed (c) The Royal Society of Chemistry
Detection of organophosphorus compounds using a surface acoustic wave array sensor based on supramolecular self-assembling imprinted films
DOI: 10.1039/D0AY00211A, Paper
In this study, diisopropyl methylphosphonate (DIMP), tributyl phosphate (TBP), and dimethyl methylphosphonate (DMMP) were selected as organophosphorus chemical warfare agent (CWA) simulants.
The content of this RSS Feed (c) The Royal Society of Chemistry
A flower-like Ag coated with molecularly imprinted polymers as surface-enhanced Raman scattering substrate for sensitive and selective detection of glibenclamide
DOI: 10.1039/D0AY00575D, Paper
The flower-like Ag, was formed by nanosheets self-assembly, as SERS active substrate was utilized for preparation of flower-like Ag@molecularly imprinted polymers (MIPs) surface-enhanced Raman scattering (SERS) sensor. Based on the...
The content of this RSS Feed (c) The Royal Society of Chemistry
Synthesis, evaluation and molecular modelling of piceatannol analogues as arginase inhibitors
DOI: 10.1039/D0MD00011F, Research Article
A quantum chemistry guided optimisation (leading to piceatannol analogue 3t) with a good understanding of the catechol binding mode to the bimanganese cluster of arginase.
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Protein—fragment complex structures derived by NMR Molecular Replacement
DOI: 10.1039/D0MD00068J, Research Article
Recently we have established an NMR Molecular Replacement method, which is capable of solving the structure of the interaction site of protein-ligand complexes in a fully automated manner. While the...
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Workforce optimization workbook for transportation construction projects / Timothy Taylor, Roy Sturgill, Steve Waddle, Ying Li, Kentucky Transportation Center; Paul Goodrum, Keith Molenaar, Sara Al-Haddad, University of Colorado Boulder
[ASAP] ICBM-OCEAN: Processing Ultrahigh-Resolution Mass Spectrometry Data of Complex Molecular Mixtures
[ASAP] Probing the Mechanism of Structure-Switching Aptamer Assembly by Super-Resolution Localization of Individual DNA Molecules
[ASAP] Breaking the Affinity Limit with Dual-Phase-Accessible Hotspot for Ultrahigh Raman Scattering of Nonadsorptive Molecules
[ASAP] Sequencing of Small DNA Fragments with Aggregated-Induced-Emission Molecule-Labeled Nucleotides
[ASAP] CycloBranch 2: Molecular Formula Annotations Applied to imzML Data Sets in Bimodal Fusion and LC-MS Data Files
[ASAP] Approximating the Strength of the Intramolecular Hydrogen Bond in 2-Fluorophenol and Related Compounds: A New Application of a Classic Technique
[ASAP] Molecular Design of Heptazine-Based Photocatalysts: Effect of Substituents on Photocatalytic Efficiency and Photostability
Why Is the UK so Much Better at Molecular Profiling?
Drs Jack West and Sanjay Popat discuss the strengths and limitations of their respective US and UK systems for identifying and treating lung cancer with actionable mutations.
Medscape Oncology
Brassica improvement: molecular, genetics and genomic perspectives / Shabir Hussain Wani, Ajay Kumar Thakur, Yasin Jeshima Khan, editors
Insect sex pheromone research and beyond: from molecules to robots / Yukio Ishikawa, editor
Role of molecular bend angle and biaxiality in the stabilization of the twist-bend nematic phase
DOI: 10.1039/D0SM00078G, Communication
Within mean-field theory for V-shaped molecules, we have investigated how the alteration of a molecule's structural features influence the stabilization of modulated and non-modulated nematic phases.
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Structural properties of contractile gels based on light-driven molecular motors: a small-angle neutron and X-ray study
DOI: 10.1039/D0SM00031K, Paper
The collective rotation of light-driven molecular motors actuates the structural changes and macroscopic contraction of the chemical gels.
The content of this RSS Feed (c) The Royal Society of Chemistry
Bi-continuous orthorhombic soft matter phase made of polycatenar molecules
DOI: 10.1039/D0SM00331J, Communication
A slight deformation of a double gyroid structure of a cubic Iād phase results in the formation of a phase with an orthorhombic Pcab symmetry. The phase seems to be an intermediate state towards a columnar phase made of helical pillars.
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Assessing the Extent of Structural and Dynamic Modulation of Membrane Lipids due to Pore Forming Toxins: Insights from Molecular Dynamics Simulations
DOI: 10.1039/D0SM00086H, Paper
Infections in many virulent bacterial strains are triggered by the release of pore forming toxins (PFTs), which form oligomeric transmembrane pore complexes on the target plasma membrane. The spatial extent...
The content of this RSS Feed (c) The Royal Society of Chemistry
Classical and Non-Classical Melatonin Receptor Agonist-Directed Micellization of Bipyridinium-Based Supramolecular Amphiphiles in Water
DOI: 10.1039/D0SM00424C, Paper
The addition of molecular recognition units into structures of amphiphiles is a means by which soft matter capable of undergoing template-directed micellization can be obtained. These supramolecular amphiphiles can bind...
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Impact of Chiral Supramolecular Nanostructure on the Mechanical and Electrical Performances of Triphenylene-based discotic physical gels
DOI: 10.1039/D0SM00152J, Paper
Discotic π-conjugated supramolecular assemblies, especially with chiral supramolecular nanostructures, have been attracting growing research interests due to their significant optoelectronic properties and the possibilities of their applications in the new...
The content of this RSS Feed (c) The Royal Society of Chemistry
Systematic approach for wettability prediction using molecular dynamics simulations
DOI: 10.1039/D0SM00197J, Paper
An efficient approach for fast screening of liquids in terms of their wetting properties.
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Saddle-curvature instability of lipid bilayer induced by amphipathicpeptides: A molecular model
DOI: 10.1039/D0SM00499E, Paper
Amphipathic peptides that partition into lipid bilayers affect the curvature elastic properties oftheir host. Some of these peptides are able to shift the Gaussian modulus to positive values, thustriggering an...
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Odisha: Headmaster arrested for attempting to molest Class X girl
Arrest made after the villagers staged a demonstration demanding action against the headmaster.
President's award winning headmaster suspended for molesting minor student
Students demand arrest of headmaster accused of molesting minor student
In lieu of a formal FIR against him, Pramod K Swain has been suspended but not arrested.
FIR against AAP's Seemapuri MLA Dharmendra Koli on molestation charge
Koli, who contested polls after his sister died, allegedly molested wife of one of the candidates.