PURPOSE

Operational failures are system-level errors in the supply of information, equipment, and materials to health care personnel. We aimed to review and synthesize the research literature to determine how operational failures in primary care affect the work of primary care physicians.

PURPOSE

The prognosis of older patients with dizziness in primary care is unknown. Our objective was to determine the prognosis and survival of patients with different subtypes and causes of dizziness.

Background:

Unnecessary antibiotic use in the community in Canada is not well defined. Our objective was to quantify unnecessary antibiotic prescribing in a Canadian primary care setting.

Background:

It is unclear how patient-reported access to primary care differs by physician payment model and participation in team-based care. We examined the association between timely and after-hours access to primary care and physician payment model and participation in team-based care, and sought to assess how access varied by patient characteristics.

Background:

Incentive payments for chronic diseases in British Columbia were intended to support primary care physicians in providing more comprehensive care, but research shows that not all physicians bill incentives and not all eligible patients have them billed on their behalf. We investigated patient and physician characteristics associated with billing incentives for chronic diseases in BC.

People with type 1 diabetes may receive a significant portion of their care from primary care providers (PCPs). To understand the involvement of PCPs in delivering type 1 diabetes care, we performed surveys in California and Florida, two of the most populous and diverse states in the United States. PCPs fill insulin prescriptions but report low confidence in providing type 1 diabetes care and difficulty accessing specialty referrals to endocrinologists.

Cruciferous vegetables have been of special interest due to the rich presence of bioactive compounds such as sulforaphane which show promising potential on cancer prevention and therapy as an epigenetic dietary strategy. Abnormal epigenetic alteration as one of the primary contributors to tumor development is closely related to breast cancer initiation and progression. In the present study, we investigated the effect of dietary broccoli sprouts (BSp), a common cruciferous vegetable, on prevention of estrogen receptor (ER)-negative mammary tumors at three different temporal exposure windows using a spontaneous breast cancer mouse model. Our findings indicate that maternal BSp treatment exhibited profound inhibitory and preventive effects on mammary cancer formation in the nontreated mouse offspring. The BSp diet administered to adult mice also showed suppressive effects on mammary cancer but was not as profound as the maternal BSp preventive effects. Moreover, such protective effects were linked with differentially expressed tumor- and epigenetic-related genes, as well as altered global histone acetylation, DNA methylation, and DNA hydroxymethylation levels. We also found that the expression changes of tumor-related genes were associated with the levels of histone methylation of H3K4 and H3K9 in the gene promoter regions. In addition, BSp-enriched sulforaphane was shown to increase protein expression of tumor suppressor genes such as p16 and p53 and inhibit the protein levels of Bmi1, DNA methyltransferases, and histone deacetylases in ERα-negative breast cancer cell lines. Collectively, these results suggest that maternal exposure to key phytochemicals may contribute to ER-negative mammary tumor prevention in their offspring through epigenetic regulations.

Bernie Sanders' bid to collect convention delegates hits snag as New York cancels Democratic presidential primary

Maryland police released body camera footage of an officer shooting and killing a man who rushed towards him with a knife.

7.45am update: Tragic pregnant mother's baby loses fight for life

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More than 14,000 London children have been turned away from their first-choice primary school, the Evening Standard can reveal today.

Primary schools are set to reopen as soon as June 1 as part of Boris Johnson's coronavirus lockdown exit strategy, The Sunday Telegraph reports.

Maggie Doherty

The post Mary Gaitskill’s Art of Loneliness appeared first on The Nation.

Here is the COVID-19 situation in Maryland and Washington, DC.

Colorado, Montana and Tennessee are among states to reopen amid coronavirus outbreak.

Five St. Mary’s County, Md., commercial fisherman pleaded guilty today to illegally overfishing striped bass also known as rockfish.

Tax return preparer Lawrence Sperling pleaded guilty today to aiding in the preparation of false tax returns. Sperling was scheduled to begin trial on April 14, 2009 before Judge Deborah Chasanow in Greenbelt, Md. According to the indictment and the plea agreement, Sperling knowingly prepared tax returns for his clients that contained false and fraudulent items, including inflated medial expenses, charitable contributions, miscellaneous employment-related expenses, and child care credits.

Thomas L. Hallock, a commercial fisherman licensed in Maryland, was sentenced today in U.S. District Court in Greenbelt, Md., to 12 months in prison, for illegally overfishing striped bass also known as rockfish. He was also fined $4,000 and ordered to pay restitution in the amount of $40,000 to the National Fish and Wildlife Foundation to the benefit of the Chesapeake Bay Striped Bass Restoration Account.

The Department filed a lawsuit in U.S. District Court in Baltimore alleging that the city of Baltimore’s zoning code discriminates against individuals with disabilities by requiring substance abuse treatment facilities to go through a burdensome “conditional ordinance” zoning process in order to locate in any zone.

William Michael King, a fifty-year-old truck driver from Maryland, pleaded guilty today to assault and violating the civil rights of an African American man he encountered while King delivered construction materials to the Pentagon.

Following a four-day trial and less than an hour of deliberations, a federal jury today convicted tax return preparer, Marcel J. Toto-Ngosso, of Silver Spring, Md., of 17 counts of preparing false tax returns in connection with a scheme to generate fraudulent tax refunds for client-taxpayers.

Two Baltimore businessmen were indicted today for conspiring to rig bids at tax lien auctions in Maryland for more than five years. The one-count felony indictment filed today in the U.S. District Court in Baltimore alleges that Harvey M. Nusbaum and his business partner, Jack W. Stollof, participated in a conspiracy to rig bids in tax lien auctions conducted by the city of Baltimore and various counties in the state of Maryland beginning in or around the Spring of 2002 and continuing until at least Aug. 9, 2007.

Defendant Paul Raymond Green was sentenced late last week to 52 months in prison and three years of supervised release for his role in a scheme to prostitute minor females. Green, 23, previously pleaded guilty to conspiracy to commit sex trafficking.

Marcel J. Toto-Ngosso of Silver Spring, Md., was sentenced to 70 months in prison today for preparing and filing false tax returns in connection with a scheme to generate fraudulent tax refunds for his clients.

A Maryland scientist who once worked for the Department of Energy, the Department of Defense and the National Aeronautics and Space Administration has been arrested for attempted espionage

U.S. District Judge Deborah K. Chasanow today sentenced Roberto Antonio Argueta, aka "Alex Antonio Cruz," aka "Buda," 29, of Hyattsville, Md., to life in prison, plus an additional 35 years, for ordering the murder of Nancy Diaz and the attempted murder of another juvenile girl.

Lloyd Mack Royal, III aka “Blyss”, aka “B”, aka “Furious” was convicted late yesterday of sex trafficking of minors and sex trafficking by force, fraud, and coercion, as well as firearm and drug charges.

Andres Echevarria, aka “B-Boy” and “King B-Boy,” pleaded guilty today to conspiracy to participate in a racketeering enterprise, in connection with his gang activities as a member of the Almighty Latin King and Queen Nation (Latin Kings).

Lloyd Mack Royal III, aka “Blyss,” “B,” and “Furious,” 29, of Gaithersburg, Md., was sentenced today by U.S. District Judge Alexander Williams Jr. for his role in a sex trafficking operation.

The United States has settled alleged violations of federal and state underground storage tank (UST) regulations at 17 gas stations in Delaware and Maryland formerly owned by Duncan Petroleum Corp.

CSI Engineering and CSI Design Build, located in Beltsville, Md., and their president, Debdas Ghosal, have agreed to pay the United States $200,000 to settle claims that they used false statements to obtain contracts from several government agencies.