The college systems, which enroll a combined 700,000 students across the state, will move to a “distance learning model,” Cuomo said at a coronavirus-related press conference Wednesday.

But it’s not clear whether elevated cholesterol is bad for birds.

Among those rallying against state shutdown orders are anti-vaccination activists. They see these protests as a way to form political alliances that promote their movement.

Play was suspended during the Ducks-Blues game on Tuesday at Honda Center after St. Louis defenseman Jay Bouwmeester collapsed on the bench during the first period.

Blues defenseman Jay Bouwmeester went into cardiac arrest during a game against the Ducks on Tuesday. Ducks medical personnel helped save his life.

A two-decade-long dry spell that has parched much of the western United States is turning into one of the deepest 'megadroughts' of the past 1,200 years.

We asked parents across the country how they're managing the new job of educating their kids. These are the tricks they rely on.

Since when is it a good idea for the president of the United States to encourage political leaders to cave in to demands by armed protesters?

Paulette Jiles delighted with her convention-breaking western romance, 'News of the World.' Her follow-up, 'Simon the Fiddler,' is just old-fashioned.

The people waving the American flag at lockdown protests are using it as a symbol of selfishness.

After putting his Playa del Rey home on the market, writer Dennis Lehane has purchased a Westchester house three miles away for $2.395 million.

Chelsea have entered negotiations with Leicester over Ben Chilwell after the left-back reportedly told his agent he wants a transfer to London.

Saddlemaker Steve Hafen talks about what it takes to build a saddle to last generations, and how family and hard work are key components in his life.

Comer was offensive coordinator for Western Boone's back-to-back state title teams

Superintendent of Public Instruction Jennifer McCormick announced Thursday that schools will stay closed for the rest of the academic year.

While a return to full, in-person classes is unlikely, IU President Michael McRobbie outlined five possibilities for the fall semester.

As colleges look to the fall semester, they're faced with the uncertainty of what it will look like. But plans are underway.

Pro chef and friend to footballers Jonny Marsh shares the secrets to one of Paul Pogba’s favourite dishes - steak with polenta fries and a chimichurri sauce.

Manchester City will continue to make part of their Etihad Campus available to the NHS, even after the Premier League returns.

The governor offered a gentle rebuke to protesters: You're not helping.

An overview of the breakaway region in eastern Moldova

Key facts about the territory disputed between Morocco and the Polisario independence movement

The former Virginia governor's book tour about white supremacy and Charlottesville was interrupted by activists who faulted McAuliffe for siding with the Virginia city's government and police.

As the Western Cape ramps up its screenings and testing for Covid-19 as confirmed cases rise, the ANC in the province is calling for the return to Level 5 lockdown to be considered.

Seventeen more Covid-19-related deaths have been recorded in the country, bringing the number to 178, while the biggest one-day spike in new cases hit 663.

Stay up to date with the latest news, views and analysis as the number of coronavirus cases in SA increases.

Cosatu in the Western Cape says that it is deeply concerned over the "alarming rate on increase" in Covid-19 infections in the province.

Western Australia

The Amateur Traveler talks to Karl Anders who returns to the show to talk about travel to Western Montana and in particular to the majestic Glacier National Park. Karl encourages us to drive the Going to the Sun Highway but then to get off the blacktop and hick some of the back country of the park (preferably in a group large enough to discourage the curiosity of bears). He describes some of his favorite hikes such as the trail to Hidden Lakes. Glacier is often rated as one of the top places in the United States to hike or backpack. The valleys of Glacier are carved by glacial activity although there aren't as many glaciers still in the park. Karl also talks about some nearby destinations like the National Bison Refuge, Bitterroot Valley and nearby Missoula with its museum to Smokejumpers.

The Amateur Traveler talks to Nathan from Wand’rly Magazine about Great Smoky Mountains National Park and about his current home of Western North Carolina. The Great Smoky Mountains National Park is the most visited U.S. National Park.

Hear about travel to Oslo and Western Norway as the Amateur Traveler talks to Øystein about his native Norway.

Hear about travel to the Western Sahara as the Amateur Traveler  talks to Francis Tapon about this disputed region as part of his trip to every country in Africa. 

Hear about a western Mediterranean cruise to Spain, Gibraltar, France, Monaco and Italy on Holland America's Westerdam where I just attended a press trip.

Hear about travel to Western Australia as the Amateur Traveler talks to Erica Carrico from ericacarrico.com about her trip to the wild and surprising Pilbara region.

Hear about travel to Pittsburgh and Western Pennsylvania as the Amateur Traveler talks to Tom Shaner about his hometown.

Hear about travel to Manchester England as the Amateur Traveler talks to Helena Ringstrom about her adopted home.

The following article, Legal Immigrant in Michigan Sends a Message to MI Gov Whitmer and Media Criticizing Freedom-Loving Protesters, was first published on 100PercentFedUp.com.

The media and even some governors are trying to paint the Americans who are protesting to open businesses up as racists and even Nazis. The Governor of Michigan recently made a derogatory statement about the protesters implying they are racists. Painting a negative picture of the people who want their freedom and businesses demonizes our […]

Continue reading: Legal Immigrant in Michigan Sends a Message to MI Gov Whitmer and Media Criticizing Freedom-Loving Protesters ...

Purinergic signaling by extracellular ATP regulates a variety of cellular events and is implicated in both normal physiology and pathophysiology. Several molecules have been associated with the release of ATP and other small molecules, but their precise contributions have been difficult to assess because of their complexity and heterogeneity. Here, we report on the results of a gain-of-function screen for modulators of hypotonicity-induced ATP release using HEK-293 cells and murine cerebellar granule neurons, along with bioluminescence, calcium FLIPR, and short hairpin RNA–based gene-silencing assays. This screen utilized the most extensive genome-wide ORF collection to date, covering 90% of human, nonredundant, protein-encoding genes. We identified two ABCG1 (ABC subfamily G member 1) variants, which regulate cellular cholesterol, as modulators of hypotonicity-induced ATP release. We found that cholesterol levels control volume-regulated anion channel–dependent ATP release. These findings reveal novel mechanisms for the regulation of ATP release and volume-regulated anion channel activity and provide critical links among cellular status, cholesterol, and purinergic signaling.

4 March 2020 , Volume 96, Number 2

James M. Ntambi
Sep 1, 1999; 40:1549-1558
Reviews

Margrit Schwarz
Sep 1, 1998; 39:1833-1843
Articles

W Gamble
Nov 1, 1978; 19:1068-1070
Articles