Everything is at stake. Everything is at stake with nuclear weapons. While working as a nuclear war planner for the Kennedy administration, Daniel Ellsberg was shown a document calculating that a U.S. nuclear attack on communist countries would result in 600 million dead. As he put it later: “A hundred Holocausts.” That was in 1961. […]

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While reports in Israel assess that Hezbollah may have lost 80 percent of its rocket arsenal and also lost 2,000 fighters, Hezbollah is putting on a brave face, claiming Israel is far from its goals.

Megan Fox's current beau Machine Gun Kelly is in “no relationship” with the actress’ ex-husband Brian Austin Green, as the couple expect their first baby together.According to TMZ, MGK and Green have had little to no contact over the past two years, with sources saying that the...

In most vertebrates, a pattern of chemical marks on the genome is a reliable indicator of age, but in axolotls this clock seems to stop after the first four years of life

They fight invaders, clear debris and tend neural connections, but sometimes microglia go rogue. Preventing this malfunction may offer new treatments for brain conditions including Alzheimer's

Experiments show that effect doesn’t always follow cause in the weird world of subatomic particles, offering fresh clues about the quantum origins of space-time

The gamma ray burst known as GRB221009A is the biggest explosion astronomers have ever glimpsed and we might finally know what caused the blast

The direction of cause and effect was brought into question for quantum objects more than a decade ago, but new calculations may offer a way to restore it

Tiny pieces of stone found in a rock formation in Western Australia may be the oldest evidence of a meteorite impact on Earth, dating back nearly 3.5 billion years

Understanding how the world’s largest-known collection of pink diamonds came to the surface in Australia around 1.3 billion years ago could help us find hidden deposits elsewhere in the world

An area of the seabed north of Australia has been mapped in detail for the first time, revealing that large numbers of people could have lived there until it was inundated by rising seas

Several enormous craters left by explosions have been spotted in Siberia over the past 15 years, and a new explanation links them to hot gas – and climate change

Seismologists were mystified by a strange signal that persisted for nine days in 2023 – now its source has been identified as a standing wave caused by a landslide in Greenland

Lake sediments reveal the ancient history of Aboriginal people’s use of fire to manage the landscape, a tradition that has benefits for biodiversity

An excavation on an island in the Coral Sea shows that Indigenous Australians were producing ceramics long before the arrival of Europeans

An excavation on Timor reveals humans first settled on the island 44,000 years ago, long after the earliest occupation of Australia – suggesting migration to the latter took another route

Wooden sticks found in an Australian cave appear to match the accounts of a 19th-century anthropologist, suggesting the GurnaiKurnai people practised the same ritual at the end of the last glacial period

We know that modern humans took one of two routes to first reach Australia, and now an ancient chunk of plant resin has tipped the evidence towards the northern option

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Visible particle is an important issue in the biopharmaceutical industry, and it may occur across all the stages in the life cycle of biologics. Upon the occurrence of visible particles, it is often necessary to conduct chemical identification and root cause analysis to safeguard the safety and efficacy of the biotherapeutic products. In this article, we present a number of typical particles and relevant root cause analysis in the categories of extrinsic, intrinsic, and inherent particles that are commonly encountered in the biopharma industry. In particular, the optical images of particles obtained both in situ and after isolation are provided, along with spectral and elemental information. The particle identification was carried out with multiple microscopic and microspectroscopic techniques, including stereo optical microscopy, Fourier-transform infrared microscopy, confocal Raman microscopy, scanning electron microscopy, and energy dispersive X-ray spectroscopy. Both commercial and in-house spectral databases were used for comparison and identification. In addition to particle identification, we placed significant efforts on the root cause analysis of the addressed particles with the intention to provide a relatively whole picture of the particle-related issues and practical references to particle mitigation for our peers in the biopharmaceutical industry.