The pilot, which was initially one of the most buzzed about pieces of ESSA, allows states to try out new forms of testing in a handful of districts, with the goal of eventually taking them statewide.

Mississippi, Arkansas, and New Mexico have the highest percentages of students who lack adequate home technology for remote learning.

Rural Iowa school superintendents and school board members unite to form new rural education advocacy group.

Minnesota and West Virginia are the first two states that submitted plans in the fall to win federal approval.

86 Sergei Bobrovsky, 85 Cole Perfetti, and 85 Alexandar Goergiev among new cards

Who is the best player in Penguins' history to wear #64?

The Calgary Flames' fifth game in eight nights and three time zones was a tough one they need to learn from

The latest update of the College Football Playoff rankings was officially released Tuesday night on ESPN, with the Alabama Crimson Tide seeing some movement as a result of their dominant 42-13 road win over the LSU Tigers on Saturday. In the rankings

Penn State moved up in this week's College Football Playoff rankings.

No. 1 Oregon will travel to Madison this weekend to take on the Wisconsin Badgers at Camp Randall Stadium.

Texas A&M's Week 11 bye week was (hopefully) successful in terms of fixing the issues that plagued the Aggies, especially the defensive issues that led to 25 missed tackles in the 44-20 loss to South Carolina, which dropped the Aggies to No. 14 in the first Col

Miami landed 9th in the latest CFP bracket. Here’s the College Football Playoff picture for the Hurricanes and path to the championship.

Penn State football landed Xth in the second CFP rankings. Here’s the College Football Playoff picture for the Nittany Lions.

The College Football Playoff Selection Committee has released its second set of rankings, and Clemson football's moved up to No. 20 following a 24-14 win over Virginia Tech. Starting at No. 23 in last week’s CFP rankings, the Tigers’ latest rise highlights thei

Here's a look at the College Football Playoff bracket and playoff picture after the latest committee rankings were released.

Notre Dame football has one remaining game against a CFP-ranked team: Nov. 23 at Yankee Stadium against No. 24 Army (9-0).

The second release of College Football Playoff rankings changes the projected bracket. Here's what it looks like if the season ended today.

With new CFP rankings having Indiana at No. 5, it's a clear sign from the Playoff committee: wins matter.

We're now eleven weeks into the college football season and that means we have an idea of where Ohio State when it comes to the landscape of the 2024 season. The Buckeyes beat Penn State on the road two weeks ago to boost its resumé and remain right

The Big Ten dominated the latest edition of the College Football Playoff (CFP) rankings, with the conference claiming four of the top five slots in the new standings revealed Tuesday night.

This Quality Counts 2019 Highlights Report captures all the data you need to assess your state's performance on key educational outcomes.

Public schools in West Virginia are closed despite a deal that was supposed to end the teacher strike today.

Michael Martirano led the state's schools through dramatic budget cuts, academic challenges, and a state-versus-local battle over school construction.

As Oklahoma teachers prepare for day four of their statewide walkout, here's a guide to the larger picture of teacher protests.

Teachers will receive a 5 percent raise, pending a vote by the state legislature. School will resume Thursday.

The West Virginia Senate trimmed the proposed pay raise for teachers from 5 percent to 4 percent, prompting union officials to declare that the strike will continue indefinitely.

The statewide teacher strike could end today if both chambers of the legislature pass the bill to deliver a 5 percent raise to all school employees.

The West Virginia House of Delegates passed its version of a sweeping education omnibus bill, which would allow the state's first charter schools.

Lawmakers effectively killed the controversial education bill that had prompted the second statewide strike in two years.

Teachers across the state will walk out of their classrooms on Tuesday to protest an education bill going through the state legislature.

This Quality Counts 2020 Highlights Report captures all the data you need to assess your state's performance on key educational outcomes.

After a couple years of clashes with teachers in the state, West Virginia Senate President Mitch Carmichael was ousted in Tuesday's Republican primary election by a teacher.

A federal investigation of Chicago's failures to respond to sexual violence in schools raises troubling questions for school districts nationwide.

AMERICUS, Ga. — Georgia Southwestern State University graduate guard Destiny Garrett was named the Peach Belt Conference Women's Basketball Player of the Week this afternoon by the league office. Garrett set a school record with 13 assists in the 17th-ranked Lady Hurricanes 85-61 win over Florida Tech on Saturday and completed her first-ever double-double with a career-best 21 points. Garrett ...

LSU women's basketball bucked a bit of a slow start to blowout Charleston Southern Tuesday morning.

Lady Vols basketball relied on its best 3-point shooting night of the season to close out a win over Middle Tennessee State on Tuesday

South Carolina football landed 21st in the latest CFP bracket. Here’s the College Football Playoff for the newly ranked No. 23 Gamecocks.

Nov. 12—The Gonzaga women's basketball team has much to learn after a challenging loss at Stanford on Sunday. Losses have a way of exposing a team's shortcomings. And there is much to learn from the worst loss (89-58) in coach Lisa Fortier's 11 seasons. Stanford, unranked in the preseason poll for the first time since 1999-2000, is unranked no more. The Cardinal (3-0) entered at No. 24 in the ...

Robbert Havekes
Dec 12, 2012; 32:18137-18149
BehavioralSystemsCognitive

Kyle E. Mathewson
Mar 4, 2009; 29:2725-2732
BehavioralSystemsCognitive

Low-intensity transcranial focused ultrasound stimulation (TUS) is a novel technique for noninvasive brain stimulation (NIBS). TUS delivered in a theta (5 Hz) burst pattern (tbTUS) induces plasticity in the human primary motor cortex (M1) for 30–60 min, showing promise for therapeutic development. Metaplasticity refers to activity-dependent changes in neural functions governing synaptic plasticity; depotentiation is the reversal of long-term potentiation (LTP) by a subsequent protocol with no effect alone. Metaplasticity can enhance plasticity induction and clinical efficacy of NIBS protocols. In our study, we compared four NIBS protocol combinations to investigate metaplasticity on tbTUS in humans of either sex. We delivered four interventions: (1) sham continuous theta burst stimulation with 150 pulses (cTBS150) followed by real tbTUS (tbTUS only), (2) real cTBS150 followed by sham tbTUS (cTBS only), (3) real cTBS150 followed by real tbTUS (metaplasticity), and (4) real tbTUS followed by real cTBS150 (depotentiation). We measured motor-evoked potential amplitude, short-interval intracortical inhibition, long-interval intracortical inhibition, intracortical facilitation (ICF), and short-interval intracortical facilitation before and up to 90 min after plasticity intervention. Plasticity effects lasted at least 60 min longer when tbTUS was primed with cTBS150 compared with tbTUS alone. Plasticity was abolished when cTBS150 was delivered after tbTUS. cTBS150 alone had no significant effect. No changes in M1 intracortical circuits were observed. Plasticity induction by tbTUS can be modified in manners consistent with homeostatic metaplasticity and depotentiation. This substantiates evidence that tbTUS induces LTP-like processes and suggests that metaplasticity can be harnessed in the therapeutic development of TUS.

Estimating the direction of functional connectivity (FC) can help further elucidate complex brain function. However, the estimation of directed FC at the voxel level in fMRI data, and evaluating its performance, has yet to be done. We therefore developed a novel directed seed-based connectivity analysis (SCA) method based on normalized pairwise Granger causality that provides greater detail and accuracy over ROI-based methods. We evaluated its performance against 145 cortical retrograde tracer injections in male and female marmosets that were used as ground truth cellular connectivity on a voxel-by-voxel basis. The receiver operating characteristic (ROC) curve was calculated for each injection, and we achieved area under the ROC curve of 0.95 for undirected and 0.942 for directed SCA in the case of high cell count threshold. This indicates that SCA can reliably estimate the strong cellular connections between voxels in fMRI data. We then used our directed SCA method to analyze the human default mode network (DMN) and found that dlPFC (dorsolateral prefrontal cortex) and temporal lobe were separated from other DMN regions, forming part of the language-network that works together with the core DMN regions. We also found that the cerebellum (Crus I-II) was strongly targeted by the posterior parietal cortices and dlPFC, but reciprocal connections were not observed. Thus, the cerebellum may not be a part of, but instead a target of, the DMN and language-network. Summarily, our novel directed SCA method, visualized with a new functional flat mapping technique, opens a new paradigm for whole-brain functional analysis.

In a new book, a curator at England's Natural History Museum describes rare and interesting nests and eggs—from the house sparrow to the village weaver—and the lessons they hold for avian conservation

A new book reveals striking images from six decades of the beloved Wildlife Photographer of the Year competition

The work of Diné artist DY Begay, now on view at the National Museum of the American Indian, blends tradition and modernity

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