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Identification of Cardiovascular Monosodium Urate Crystal Deposition in Gout Using Dual-Energy CT

To the Editor We read the recent article by Klauser et al with great interest. While the potential implications of the findings are exciting, we have several concerns. First, the authors do not explicitly state whether electrocardiogram gating was used in their study. This is an important detail because cardiac motion artifact is a source of artifactual coloration with dual-energy computed tomography (DECT), particularly with dual-source scanners given the approximately 80-millisecond temporal difference between the 2 radiography beams. Furthermore, beam hardening artifact from calcified atheromas and partial volume effect, known sources of artifacts in the 2-material decomposition algorithm of DECT, may largely explain the findings. While patients with gout had higher prevalence of coronary calcification (55 of 59 patients [93%]) and cardiovascular monosodium urate (MSU) deposition (51 of 59 patients [86%]) than controls, the authors do not report whether the 4 patients with gout without coronary calcifications exhibited MSU deposition nor the number of controls or cadaveric hearts with coronary calcification. The images from the article show areas of green pixelization occurring adjacent to calcified plaques on grayscale computed tomography images (eg, Figure 2A and D, left anterior descending artery [yellow arrowhead]), which would favor this artifact hypothesis without additional data.




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Identification of Cardiovascular Monosodium Urate Crystal Deposition in Gout Using Dual-Energy CT—Reply

In Reply We appreciate the valuable comments of Becce et al on our article. We applied prospective electrocardiography gating using a thin-slice cardiac protocol to ensure highest spatial resolution with minimal motion artifact. A noncontrast electrocardiography-gated computed tomography (CT) examination with standardized scan parameters was performed using a 128-slice dual-source CT (SOMATOM Definition Flash; Siemens) with a detector collimation of 2 × 64 × 0.6 mm, rotation time of 0.28 seconds, and prospective electrocardiography triggering for heart rates less than 65 beats per minute (diastolic padding, 70% of RR interval) and more than 65 beats per minute (systolic padding, 40% of RR interval). Axial images were reconstructed with 0.75-mm slice width, increment of 0.5, and a medium-smooth convolution kernel (B26f). When motion artifact was present, it was distinguished by visual analysis of an experienced observer and colorized pixels related to motion were excluded.




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McManus-Young clipping collection of materials on magic, 1870-1955 [Revised Finding Aid]

With a date span of 1779 through 1955, the McManus-Young Collection provides a rich survey of the literature of "illusion practices," which includes works on conjuring, ventriloquism, fortune-telling, spiritualism, witchcraft, gambling, hypnotism, automata, and mind reading comprised of a gathering of thousands of pamphlets and offprints. This ephemeral literature is the backbone of modern...




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Music of Machito and his Afro-Cubans, 1930s-1980s [New Finding Aid]

Latin jazz musician and band leader Machito (circa 1908-1984) was active on the New York City jazz scene with his innovative band the Afro-Cubans from 1940 to the early 1980s, forming an influential legacy that includes salsa music and Afro-Cuban jazz. The collection contains approximately 150 manuscript and published compositions and arrangements performed by the ensemble, as well as clippings,...




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USP for BJP

As the last phase of campaigning picks up steam, Modi should clearly advocate economic growth and the positive impact it has on all Indians.




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There's a profusion of movie stars contesting 2014 polls

Movie stars in 2014's polls are a welcome addition to the fray. For those carping about how stars represent glamour and gloss, why not?




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Congress manifesto swings rightward on economic policy and yet promises to push ahead with populism

The Congress manifesto is the polar opposite of policies pursued by UPA-II. It promises to undo measures that clogged the economy and make economic growth the "overriding priority".




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Treat us as friends and we will never let you down, Trinamool says to NDA

Trinamool Congress appears ready to move forward from the ferocious acrimony of Mamata-Modi exchanges during the election campaign.




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Following Karachi strikes, Pakistan must take decisive steps to destroy terror infrastructure

Going by a letter written by Nawaz Sharif to Narendra Modi, that he was 'much satisfied' with their meeting in New Delhi, the two prime ministers have succeeded in striking up a working relationship.




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[ASAP] Fast Magneto-Ionic Switching of Interface Anisotropy Using Yttria-Stabilized Zirconia Gate Oxide

Nano Letters
DOI: 10.1021/acs.nanolett.0c00340




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[ASAP] Overcoming Hypoxia-Restrained Radiotherapy Using an Erythrocyte-Inspired and Glucose-Activatable Platform

Nano Letters
DOI: 10.1021/acs.nanolett.0c00650




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[ASAP] Simultaneous Intravital Optical and Acoustic Monitoring of Ultrasound-Triggered Nanobubble Generation and Extravasation

Nano Letters
DOI: 10.1021/acs.nanolett.0c01310




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State party report on the state of conservation of the Great Barrier Reef World Heritage Area (Australia) : in response to the World Heritage Committee decision WHC 38 COM 7B.63




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Australia's environment / Environment and Communications References Committee

Australia. Parliament. Senate. Environment and Communications References Committee, author




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Ocean sustainability in the 21st century / edited by Salvatore Aricò




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Australia's water markets : an evaluation of Australia's water market as a new global standard for managing water resources / Manabu Kondo

Kondo, Manabu, author




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Marine ecosystems : human impacts on biodiversity, functioning and services / edited by Tasman P. Crowe, University College Dublin, Ireland, Christopher L.J. Frid, Griffith University, Queensland, Australia




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Marine biology / Peter Castro, Ph.D., California State Polytechnic University, Pomona, Michael E. Huber, Ph.D., Jacobs Australia ; original artwork by William C. Ober, M.D., Washington & Lee University, and Claire E. Ober, B.A., R.N

Castro, Peter, author




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Conservation education and outreach techniques / Susan K. Jacobson, Mallory D. McDuff, and Martha C. Monroe

Jacobson, Susan Kay, author




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Impact of water pollution on human health and environmental sustainability / A. Elaine McKeown, Independent Researcher, USA, George Bugyi, Pennsylvania State University, USA




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Coastal and marine stewardship in Western Australia : the case for a virtue ethic / John Davis

Davis, John K., author




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Toxic tide: the threat of marine plastic pollution in Australia / The Senate, Environment and Communications References Committee

Australia. Parliament. Senate. Environment and Communications References Committee, author, issuing body




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Solving the groundwater challenges of the 21st century / editor, Ryan Vogwill, School of Earth and Environment, University of Western Australia, Crawley Australia




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Population biology of the sand dollar, Peronella lesueuri, in Cockburn Sound, southwest Australia / Sharon Yeo Sue-Yee

Yeo, Sue-Yee Sharon, author




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Pollution status, environmental protection, and renewable energy production in marine systems / Ahmed El Nemr, editor




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Implications of habitat type on the hyperbenthos of two morphologically divergent estuaries, and their adjacent nearshore marine waters, along the lower west coast of Australia / Natahsa Jeanne Coen

Coen, Natasha Jeanne, author




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The Deep Sea Drilling Project--a decade of progress / based on a symposium sponsored by SEPM-AAPG, held at the annual meeting, Houston, Texas, 1979, with additional related contributions ; edited by John E. Warme, Robert G. Douglas, and Edward L. Winterer




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Hydroacoustic ocean exploration : theories and experimental application / I. B. Abbasov

Abbasov, Iftikhar Balakishi ogly, author




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International water scarcity and variability : managing resource use across political boundaries / Shlomi Dinar and Ariel Dinar

Dinar, Shlomi, author




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Introduction to physical oceanography / John A. Knauss (late of University of Rhode Island), Newell Garfield (Southwest Fisheries Science Center)

Knauss, John A., author




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Bush Heritage Australia : restoring nature step by step / Sarah Martin

Martin, Sarah, author




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The marine world : a natural history of ocean life / Frances Dipper ; illustrated by Marc Dando

Dipper, Frances, 1951- author




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Aquatic pollution : an introductory text / Edward A. Laws, Los Angeles, US

Laws, Edward A., 1945- author




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Tropical marine life of Australia : plants and animals of the central Indo-Pacific / Graham Edgar

Edger, Graham, author, photographer




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Australia state of the environment 2016 overview / W.J. Jackson [and 17 others]

Jackson, W. J., author




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Towards a healthy, working Murray-Darling basin : basin plan annual report 2015-16 / Australian Government, Murray Darling Basin Authority

Murray-Darling Basin Authority (Australia)




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Decision making in water resources policy and management : an Australian perspective / Barry T. Hart (Water Science Pty Ltd, Echuca and Monash University, Melbourne, VIC, Australia), Jane Doolan (University of Canberra, ACT, Australia)

Hart, Barry T., author




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Commercial and institutional end uses of water / prepared by Benedykt Dziegielewski ... [et al.]




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The water-food-energy nexus : processes, technologies, and challenges / edited by I.M. Mujtaba, R. Srinivasan, N.O. Elbashir




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Essentials of oceanography / Alan P. Trujillo (Distinguished Teaching Professor, Palomar College), Harold V. Thurman (Former Professor Emeritus, MT. San Antonio College)

Trujillo, Alan P., author




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Marine pollution / Christopher L.J. Frid (School of Environment, Griffith University, Queensland, Australia), Bryony A. Caswell (Environmental Futures Research Institute, Griffith University, Queensland, Australia)

Frid, Chris, author




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The rise of marine mammals : 50 million years of evolution / Annalisa Berta ; graphics editor, James L. Sumich ; illustrations by Carl Buell, Robert Boessenecker, William Stout, and Ray Troll

Berta, Annalisa, author




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Evolutionary ecology of marine invertebrate larvae / edited by Tyler J. Carrier (University of North Carolina at Charlotte, USA), Adam M. Reitzel (University of North Carolina at Charlotte, USA), Andreas Heyland (University of Guelph, Canada)




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Microplastics in fisheries and aquaculture : status of knowledge on their occurrence and implications for aquatic organisms and food safety / Amy Lusher, Peter Hollman, and Jeremy Mendoza-Hill

Lusher, Amy, author




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Making every drop count : inquiry into water use efficiency programs in agriculture / House of Representatives, Standing Committee on Agriculture and Water Resources

Australia. Parliament. House of Representatives. Standing Committee on Agriculture and Water Resources, author




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Revitalizing urban waterway communities : streams of environmental justice / Richard Smardon, Sharon Moran, and April Karen Baptiste ; with contributions from Blake Neumann and Jill Weiss

Smardon, Richard C., author




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Coral whisperers : scientists on the brink / Irus Braverman

Braverman, Irus, 1970- author




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The sea around us / Rachel Carson ; introduction by Sylvia Earle

Carson, Rachel, 1907-1964, author




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Oceans : science and solutions for Australia / editor: Bruce Mapstone




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Report on the inquiry into the management and use of Commonwealth environmental water : Inquiry into the management and use of Commonwealth environmental water / House of Representatives Standing Committee on the Environment and Energy

Australia. Parliament. House of Representatives. Standing Committee on the Environment and Energy, author, issuing body