Interview with Dana Dabelea, MD, PhD, author of Prevalence of Type 1 and Type 2 Diabetes Among Children and Adolescents From 2001 to 2009

Interview with Christianne L. Roumie, MD, MPH, author of Association Between Intensification of Metformin Treatment With Insulin vs Sulfonylureas and Cardiovascular Events and All-Cause Mortality Among Patients With Diabetes

Interview with Joseph B. Muhlestein, MD, author of Effect of Screening for Coronary Artery Disease Using CT Angiography on Mortality and Cardiac Events in High-Risk Patients With Diabetes

Interview with David M. Nathan, MD, author of Association Between 7 Years of Intensive Treatment of Type 1 Diabetes and Long-term Mortality

Interview with Anny H. Xiang, PhD, author of Association of Maternal Diabetes With Autism in Offspring

Interview with Ezio Bonifacio, PhD, author of Effects of High-Dose Oral Insulin on Immune Responses in Children at High Risk for Type 1 Diabetes: The Pre-POINT Randomized Clinical Trial

Interview with Andy Menke, PhD, author of Prevalence of and Trends in Diabetes Among Adults in the United States, 1988-2012

Interview with Ingrid M. Libman, MD, PhD, author of Effect of Metformin Added to Insulin on Glycemic Control Among Overweight/Obese Adolescents With Type 1 Diabetes

Polypharmacy is a rapidly worsening problem that hits elderly patients particularly hard.  As patients grow older, they need more medications but at the same time become less capable of managing the complexity of drug treatments.  In order to simplify treatment regimens for older patients, it is necessary to consider the evidence supporting treatment of various conditions and when the evidence is not particularly strong, reduce or eliminate medications accordingly.  Diabetes management in the elderly is highlighted in this podcast with specific attention given to deintensifying diabetes treatment in the elderly.

Articles discussed in this episode:

• Polypharmacy in the Aging Patient: Glycemic Control in Older Adults With Type 2 Diabetes: A Review (Kasia J. Lipska, MD, MHS)
• Evaluation and Treatment of Older Patients With Hypercholesterolemia: A Clinical Review (Timo E. Strandberg, MD, PhD)
• Trends in Prescription Drug Use Among Adults in the United States From 1999-2012 (Elizabeth D. Kantor, PhD, MPH)

Interview with Gillian L. Booth, MD, author of Association of Neighborhood Walkability With Change in Overweight, Obesity, and Diabetes

Online Resource

Type 2 diabetes drug metformin impedes glucose overproduction in a redox-dependent manner, researchers say