When Mary the Virgin was about fourteen years old, the Archangel Gabriel came to Joseph's dwelling, where she was living, and said to her, 'Rejoice, thou Full of Grace, the Lord is with thee: blessed art thou among women.' Receiving assurance that she had been chosen to be the Mother of God Himself, she answered in humility, 'Behold the handmaid of the Lord; be it unto me according to thy word.' Immediately, the Holy Spirit came upon her, the power of the Most High overshadowed her, and the Incarnation, long awaited by the whole creation, took place: He who contains the whole universe consented to be contained in the womb of one woman, the most holy Theotokos.   The Church teaches us that it was within the holy Virgin's power to refuse the divine conception: her knowing and willing acceptance, the consummation of the faith of the whole righteous remnant of Israel, shows us that our very salvation is the fruit of the cooperation (synergia) of human faithfulness with God's saving grace.   Carrying in her womb the Savior of the Universe, the Virgin went to the hills of Judea to stay with her kinswoman Elizabeth, who six months before had conceived in her old age (by Zacharias the priest) St John the Forerunner. As the holy Virgin approached, the child John leaped in his mother's womb for joy, prophesying the coming of Emmanuel. Feeling the prophecy, Elizabeth was filled with the Holy Spirit and blessed the holy Mary and the fruit of her womb. And Mary in turn glorified God, saying 'My soul doth magnify the Lord, and my spirit hath rejoiced in God my Savior' (Luke ch. 1).

These three sisters lived in Aquilea. When the Emperor Diocletian was visiting there, he learned that they were Christians and had them brought to him. When they would not deny Christ, they were cast into prison, then handed over to a general named Dulcitius for torture. Dulcitius conceived a passion for the sisters, and entered the prison planning to defile them; but when he tried to enter, he was deprived of his reason and fell upon the dirty pots at the entrance, embracing and kissing them until he was completely black with soot. Hearing of this, the Emperor appointed another general to torment the sisters. After terrible tortures Agape and Chionia were burned, but the sadistic general, knowing her pledge of virginity to the Lord, ordered Irene to be put in a brothel. By God's providence she was shot with an arrow before she could be forced to endure this fate.   So ends the version given in the Great Horologion. The Prologue gives a slightly different version: When Irene was being led to the brothel, an angel turned the soldiers back and led Irene to the top of a high hill. The next day the general came with his soldiers to capture her, but were unable to climb it. The general then ordered that Irene be shot with arrows.   St Anastasia, a prophetess in that town, gathered the bodies of all three sisters and gave them burial.

Licinius was co-emperor with Constantine the Great. At his accession, he had agreed to tolerate Christianity in his territories, but soon turned to persecuting the Christians, and to a variety of carnal sins. He conceived a passion for Glaphyra, a Christian virgin handmaid of the Empress Constantia. When Glaphyra told Constantia of this, the Empress sent her away to Amasia in the East for her protection. There she was received and protected by Bishop Basil of that city. Licinius learned where Glaphyra was hiding and ordered that both she and the bishop be brought to him as prisoners. The soldiers who came for her found that she had already died, so they returned with only Bishop Basil, who was subjected to cruel tortures, then beheaded. His body was cast into the sea, but, with the help of an angel of God, his people found his body, retrieved it from the sea, and returned it to Amasia.   The Prologue adds, "The Emperor Constantine raised an army against Licinius, overcame him, arrested him and sent him into exile in Gaul, where he ended his God-hating days."

At a pagan festival in Thrace, when the Governor of the region was offering sacrifice to the idols, St Glyceria entered the temple and declared herself to be a handmaid of Christ. When the governor commanded her to make sacrifice to the gods, she overturned the statue of Zeus, smashing it to pieces. For this, and for her continued refusal to deny her faith, she was seized and subjected to many tortures. First, the governor had her sealed in a prison cell with the intention of starving her to death; but an angel appeared to Glykeria and gave her heavenly food. When enough time had passed that the governor was certain that Glykeria had perished, he opened her cell, and all present were astonished to see her alive, healthy and full of joy. At this her jailer, Laodicius, confessed Christ and was beheaded. Glykeria was then thrown into a fire, but stood in it unharmed, praising God like the Three Children in Babylon. Finally she was cast to wild beasts, where she gave up her soul to God. A healing myrrh flowed from her relics.

Theodotus was a married inn-keeper in Ancyra during the persecutions of Diocletian. He used his inn-keeping trade as a means of secretly helping the persecuted Christians, many of whom used his inn as a refuge in time of need. One of his holy works was to retrieve the bodies of martyred Christians and give them burial. At that time, seven maidens were tried and tortured for their faith in Christ, then killed by being thrown into a lake. One of them, St Tecusa, appeared to St Theodotus and asked him to retrieve the bodies of her and her sisters in Christ. Under cover of night Theodotus, guided by an Angel, was able to find all seven bodies and bury them honorably. But a friend whom he had asked to help him in this work betrayed him, and he was arrested and subjected to cruel tortures. Finally he was sentenced to be beheaded. As he went to the block, he said to the many Christians who had gathered to weep for him: 'Do not weep for me, brethren, but glorify our Lord Jesus Christ, by whose aid I am finishing my course and overcoming the enemy.' A church dedicated to him was later built on the site of his burial.

During the persecutions of the Emperor Maximian, the virgin Theodosia came to comfort a group of Christians who were standing before the governor of Caesarea in Palestine. When she encouraged them not to shun martyrdom, she too was brought before the judge, who ordered that a stone be tied around her neck and that she be thrown into the sea; but angels carried her to shore unharmed. The judge then ordered that she be beheaded. The night that the sentence was carried out, Theodosia appeared to her parents, surrounded by heavenly light and accompanied by other virgin martyrs, and said, 'Do you see how great is the glory and grace of my Christ, of which you wished to deprive me?' (Her parents, wishing to preserve her from martyrdom, had tried to prevent her from confessing Christ).

On the Cross, the Lord charged the Apostle John to care for His holy Mother. The Apostle settled her in a house in Jerusalem, where she lived for the rest of her days on earth, praying and offering counsel and encouragement to the Apostles. In her old age, the Archangel Gabriel appeared to her and told her that in three days' time she would enter into her rest. Giving thanks to God, she hastened to the Mount of Olives where she prayed continually, preparing herself to meet the Lord. Meanwhile, the Apostles, scattered in various parts of the earth, were caught up in clouds and miraculously brought by the holy Angels to Jerusalem, so that they might all be with the Theotokos at her repose. After she had blessed them, she gave up her soul to God. The Apostles buried her with all honor, solemnity and joy at Gethsemane. The Apostle Thomas, who was delayed (again!) by God's providence, arrived on the third day and went to her tomb, intending to honor her. But when the Apostles opened her grave, they found her holy body gone and only the winding-sheet remaining. That evening the Theotokos appeared to them surrounded by angels, and said to them, 'Rejoice: I will be with you always!'. Thus they learned that she had been bodily translated to heaven, anticipating the general resurrection of all. Her age at her repose is not known, but many say that she was about sixty years old.

She lived in Rome during the reigns of the Emperors Decius and Valerian. At an early age she left all to embrace a life of unceasing prayer, entering a small monastery in Rome, directed by a nun named Sophia. For her Christian faith, she was seized and brought before the governor Probus and, when she boldly confessed Christ and refused to honor the idols, was subjected to a series of vicious tortures, under which she died. An angel led Sophia to retrieve her holy relics, which are now venerated at the monastery of Grigoriou on Mt Athos.   We are sometimes told that monasticism developed in the Church after Christianity became accepted and grew more worldly. The story of St Anastasia is one of many evidences in the lives of the Saints that what we now call monasticism was present from the earliest days of the Church.