ultrasound

Thoracic ultrasound in the modern management of pleural disease

Physician-led thoracic ultrasound (TUS) has substantially changed how respiratory disorders, and in particular pleural diseases, are managed. The use of TUS as a point-of-care test enables the respiratory physician to quickly and accurately diagnose pleural pathology and ensure safe access to the pleural space during thoracentesis or chest drain insertion. Competence in performing TUS is now an obligatory part of respiratory speciality training programmes in different parts of the world. Pleural physicians with higher levels of competence routinely use TUS during the planning and execution of more sophisticated diagnostic and therapeutic interventions, such as core needle pleural biopsies, image-guided drain insertion and medical thoracoscopy. Current research is gauging the potential of TUS in predicting the outcome of different pleural interventions and how it can aid in tailoring the optimum treatment according to different TUS-based parameters.




ultrasound

Efficacy of Affibody-Based Ultrasound Molecular Imaging of Vascular B7-H3 for Breast Cancer Detection

Purpose:

Human B7-H3 (hB7-H3) is a promising molecular imaging target differentially expressed on the neovasculature of breast cancer and has been validated for preclinical ultrasound (US) imaging with anti–B7-H3-antibody-functionalized microbubbles (MB). However, smaller ligands such as affibodies (ABY) are more suitable for the design of clinical-grade targeted MB.

Experimental Design:

Binding of ABYB7-H3 was confirmed with soluble and cell-surface B7-H3 by flow cytometry. MB were functionalized with ABYB7-H3 or anti–B7-H3-antibody (AbB7-H3). Control and targeted MB were tested for binding to hB7-H3–expressing cells (MS1hB7-H3) under shear stress conditions. US imaging was performed with MBABY-B7-H3 in an orthotopic mouse model of human MDA-MB-231 coimplanted with MS1hB7-H3 or control MS1WT cells and a transgenic mouse model of breast cancer development.

Results:

ABYB7-H3 specifically binds to MS1hB7-H3 and murine-B7-H3–expressing monocytes. MBABY-B7-H3 (8.5 ± 1.4 MB/cell) and MBAb-B7-H3 (9.8 ± 1.3 MB/cell) showed significantly higher (P < 0.0001) binding to the MS1hB7-H3 cells compared with control MBNon-targeted (0.5 ± 0.1 MB/cell) under shear stress conditions. In vivo, MBABY-B7-H3 produced significantly higher (P < 0.04) imaging signal in orthotopic tumors coengrafted with MS1hB7-H3 (8.4 ± 3.3 a.u.) compared with tumors with MS1WT cells (1.4 ± 1.0 a.u.). In the transgenic mouse tumors, MBABY-B7-H3 (9.6 ± 2.0 a.u.) produced higher (P < 0.0002) imaging signal compared with MBNon-targeted (1.3 ± 0.3 a.u.), whereas MBABY-B7-H3 signal in normal mammary glands and tumors with B7-H3 blocking significantly reduced (P < 0.02) imaging signal.

Conclusions:

MBABY-B7-H3 enhances B7-H3 molecular signal in breast tumors, improving cancer detection, while offering the advantages of a small size ligand and easier production for clinical imaging.




ultrasound

Radiomics Study of Thyroid Ultrasound for Predicting BRAF Mutation in Papillary Thyroid Carcinoma: Preliminary Results [FUNCTIONAL]

BACKGROUND AND PURPOSE:

It is not known how radiomics using ultrasound images contribute to the detection of BRAF mutation. This study aimed to evaluate whether a radiomics study of gray-scale ultrasound can predict the presence or absence of B-Raf proto-oncogene, serine/threonine kinase (BRAF) mutation in papillary thyroid cancer.

MATERIALS AND METHODS:

The study retrospectively included 96 thyroid nodules that were surgically confirmed papillary thyroid cancers between January 2012 and June 2013. BRAF mutation was positive in 48 nodules and negative in 48 nodules. For analysis, ROIs from the nodules were demarcated manually on both longitudinal and transverse sonographic images. We extracted a total of 86 radiomics features derived from histogram parameters, gray-level co-occurrence matrix, intensity size zone matrix, and shape features. These features were used to build 3 different classifier models, including logistic regression, support vector machine, and random forest using 5-fold cross-validation. The performance including accuracy, sensitivity, specificity, positive predictive value, negative predictive value, and area under the receiver operating characteristic curve, of the different models was evaluated.

RESULTS:

The incidence of high-suspicion nodules diagnosed on ultrasound was higher in the BRAF mutation–positive group than in the mutation–negative group (P = .004). The radiomics approach demonstrated that all classification models showed moderate performance for predicting the presence of BRAF mutation in papillary thyroid cancers with an area under the curve value of 0.651, accuracy of 64.3%, sensitivity of 66.8%, and specificity of 61.8%, on average, for the 3 models.

CONCLUSIONS:

Radiomics study using thyroid sonography is limited in predicting the BRAF mutation status of papillary thyroid carcinoma. Further studies will be needed to validate our results using various diagnostic methods.




ultrasound

Focused ultrasound opening brain to previously impossible treatments

Focused ultrasound, the researchers hope, could revolutionize treatment for conditions from Alzheimer's to epilepsy to brain tumors -- and even help repair the devastating damage caused by stroke.




ultrasound

Ciara FaceTimes hubby Russell Wilson during ultrasound

American singer Ciara, who is expecting her second child with National Football League (NFL) star hubby Russell Wilson, has some advice for pregnant women during the COVID-19 pandemic. Several hospitals and healthcare facilities in many countries have decided to ban partners from accompanying pregnant women for their doctor's appointments or entering the delivery room.

In a recent interview with Good Morning America, Ciara spoke about how pregnant women should make optimum use of technology to involve their partners during the maternity period.

Ciara revealed how she had to FaceTime Russell so that he could experience the ultrasound with her. "It was the first time we ever had that kind of experience and it was really a moment that marked the time we are living in... we made the best of it, but it was definitely surreal. I took tons and tons of videos, tons and tons of photos during the ultrasound and made the best of that. Also, what we do in our house is we sing to the belly," Ciara said.

Catch up on all the latest sports news and updates here. Also download the new mid-day Android and iOS apps to get latest updates.

Mid-Day is now on Telegram. Click here to join our channel (@middayinfomedialtd) and stay updated with the latest news




ultrasound

Mandatory Training for Ultrasound: Indian Supreme Court Has Put High Court's Order on Hold

The Supreme Court of India has put Delhi high court order on hold to allow the MBBS practitioners to access the ultrasound. The stated order has come




ultrasound

Ultrasound-assisted Molecule Delivery Looks to Preserve Blood for Years: Study

A novel way to use ultrasound to create pores in blood cells, which allows the molecule trehalose to enter the cells and prevent their degradation when




ultrasound

My Kitchen Rules' Jess Alvial shares ultrasound of her unborn baby

The 31-year-old joked in the caption that her little one is already taking after his mother, writing: 'When he has his mummy’s pout already!!'




ultrasound

Katy Perry: daughter flashes the middle finger during an ultrasound

'I went to a doctor's appointment yesterday and I had an ultrasound and she was moving around,' said the fiancee of actor Orlando Bloom. 'I have a video of her giving me the middle finger.'




ultrasound

Blac Chyna's fake pregnancy post: Star uploads then deletes ultrasound photo from ANOTHER WOMAN

The 31-year-old cosmetics mogul - real name Angela White - took to her Instagram on Tuesday to share the image which was captioned simply:  'Blessed 2020.'




ultrasound

[ASAP] Ultrasound-Enhanced Chemo-Photodynamic Combination Therapy by Using Albumin “Nanoglue”-Based Nanotheranostics

ACS Nano
DOI: 10.1021/acsnano.9b09827




ultrasound

A general method to greatly enhance ultrasound-responsiveness for common polymeric assemblies

Polym. Chem., 2020, Advance Article
DOI: 10.1039/D0PY00254B, Paper
Jinkang Dou, Ruiqi Yang, Kun Du, Li Jiang, Xiayun Huang, Daoyong Chen
Ultrasound-controlled drug release is a very promising technique for controlled drug delivery due to the unique advantages of ultrasound as the stimulus.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




ultrasound

Room Temperature Synthesis of Block Copolymer Nano-Objects with Different Morphologies via Ultrasound Initiated RAFT Polymerization-Induced Self-Assembly (Sono-RAFT-PISA)

Polym. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0PY00461H, Paper
Jing Wan, Bo Fan, Yiyi Liu, Tina Hsia, Kaiyuan Qin, Tanja Junkers, Boon M. Teo, San Thang
Polymerization-induced self-assembly (PISA), which allows scalable synthesis of nano-objects, has drawn significant research attention in the past decade. However, the initiation methods in most of the current reported PISA are...
The content of this RSS Feed (c) The Royal Society of Chemistry




ultrasound

Ultrasound-assisted extraction of bioactive alkaloids from Phellodendri amurensis cortex using deep eutectic solvent aqueous solutions

New J. Chem., 2020, Advance Article
DOI: 10.1039/D0NJ00877J, Paper
Yuanbin Li, Zuchen Pan, Binshen Wang, Wen Yu, Siwei Song, Huanhuan Feng, Weiwei Zhao, Jiaheng Zhang
ChCl/citric acid-based DESs are demonstrated to be effective green solvents for the ultrasound-assisted extraction of bioactive alkaloids from herbs.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




ultrasound

Symposium and workshop on ultrasound, 12th-13th October, 1985 : venue, University Farm, Camden, New South Wales / organised and run by D. I. Bryden

University of Sydney. Post-Graduate Committee in Veterinary Science




ultrasound

Medical imaging based on magnetic fields and ultrasounds / edited by Hervé Fanet




ultrasound

Point of care ultrasound / Nilam J. Soni, Robert Arntfield, Pierre Kory

Soni, Nilam J., author




ultrasound

Practical guide to emergency ultrasound / [edited by] Karen S. Cosby, John L. Kendall




ultrasound

General and vascular ultrasound : case review / John McGahan, Sharlene A. Teefey, Laurence Needleman

McGahan, John P., author




ultrasound

Ultrasound (Scoutt)




ultrasound

Ultrasound in anesthetic practice




ultrasound

Introduction to ultrasound, sonochemistry and sonoelectrochemistry / Bruno G. Pollet, Muthupandian Ashokkumar

Online Resource




ultrasound

Therapeutic ultrasound in dentistry: applications for dentofacial repair, regeneration, and tissue engineering / Tarek E-Bialy, Eiji Tanaka, Dror Aizenbud, editors

Online Resource




ultrasound

The ultimate guide to point-of-care ultrasound-guided procedures / Srikar Adhikari, Michael Blaivas, editors

Online Resource




ultrasound

Multi-residue determination of micropollutants in Nigerian fish from Lagos lagoon using ultrasound assisted extraction, solid phase extraction and ultra-high-performance liquid chromatography tandem mass spectrometry

Anal. Methods, 2020, 12,2114-2122
DOI: 10.1039/D0AY00411A, Paper
Idera Fabunmi, Natalie Sims, Kathryn Proctor, Aderonke Oyeyiola, Temilola Oluseyi, Kehinde Olayinka, Barbara Kasprzyk-Hordern
This reports for the first time a simple and robust approach in determining pharmaceuticals in different fish species in Nigeria.
The content of this RSS Feed (c) The Royal Society of Chemistry




ultrasound

Multivariate optimization of an ultrasound-assisted extraction procedure for the determination of Cu, Fe, Mn, and Zn in plant samples by flame atomic absorption spectrometry

Anal. Methods, 2020, Advance Article
DOI: 10.1039/D0AY00554A, Paper
Floriatan Santos Costa, Raquel Viana Pinto Leal, Clissiane Soares Viana Pacheco, Fábio Alan Carqueija Amorim, Raildo Mota de Jesus, Luana Novaes Santos, Erik Galvão Paranhos da Silva
A new ultrasound-assisted extraction method simple and fast was developed employing multivariate optimization.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




ultrasound

Interventional ultrasound of the breast: from biopsy to ablation / Bruno D. Fornage

Online Resource




ultrasound

[ASAP] Simultaneous Intravital Optical and Acoustic Monitoring of Ultrasound-Triggered Nanobubble Generation and Extravasation

Nano Letters
DOI: 10.1021/acs.nanolett.0c01310




ultrasound

Ultrasound contrast agent enhances tissue imaging

Polymer-coated silica nanoparticles swell in response to pH changes




ultrasound

[ASAP] Ultrasound Enhances ZD2767P–Carboxypeptidase G2 against Chemoresistant Ovarian Cancer Cells by Altering the Intracellular Pharmacokinetics of ZD2767D

Molecular Pharmaceutics
DOI: 10.1021/acs.molpharmaceut.0c00008




ultrasound

Detection of Breast Cancer With Addition of Annual Screening Ultrasound or a Single Screening MRI to Mammography in Women With Elevated Breast Cancer Risk

Interview with Wendie A. Berg, MD, PhD, author of Detection of Breast Cancer With Addition of Annual Screening Ultrasound or a Single Screening MRI to Mammography in Women With Elevated Breast Cancer Risk




ultrasound

MR/Ultrasound Fusion Biopsy for Prostate Cancer

Interview with Peter A. Pinto, MD, author of Comparison of MR/Ultrasound Fusion-Guided Biopsy With Ultrasound-Guided Biopsy for the Diagnosis of Prostate Cancer




ultrasound

In situ conversion of rose bengal microbubbles into nanoparticles for ultrasound imaging guided sonodynamic therapy with enhanced antitumor efficacy

Biomater. Sci., 2020, 8,2526-2536
DOI: 10.1039/C9BM02046B, Paper
Rui Hou, Xiaolong Liang, Xiaoda Li, Xu Zhang, Xiaotu Ma, Fan Wang
Sonosensitizer microbubbles enhance drug accumulation and the antitumor efficacy of sonodynamic therapy by ultrasound mediated micro to nano conversion.
The content of this RSS Feed (c) The Royal Society of Chemistry




ultrasound

Ultrasound hardware setup for CMP pad characterization




ultrasound

Reliability of hand measures of ultrasound analysis




ultrasound

[ASAP] Ultrasound Responsive Magnetic Mesoporous Silica Nanoparticle-Loaded Microbubbles for Efficient Gene Delivery

ACS Biomaterials Science & Engineering
DOI: 10.1021/acsbiomaterials.0c00014




ultrasound

[ASAP] Ultrasound Enhanced Synthetic Platelet Therapy for Augmented Wound Repair

ACS Biomaterials Science & Engineering
DOI: 10.1021/acsbiomaterials.9b01976




ultrasound

Therapeutic endoscopic ultrasound Evangelos Kalaitzakis, Peter Vilmann, Manoop S. Bhutani, editors

Online Resource




ultrasound

Diagnostic ultrasound for sonographers / Aya Kamaya [and 7 others]




ultrasound

Essential ultrasound anatomy / Marios Loukas, Danny Burns

Loukas, Marios, author