Singapore-based TransferTo has partnered with the Pan-African Ecobank Group in order to expand financial access and cross-border payments across the region of Africa.

The Catawba County Board of Commissioners, at its January 19, 2010 meeting, joined with other local governments across the region in approving the agreement. The main points of the agreement hinged on Concord and Kannapolis modifying their ability, contained in their IBT certificate, to withdraw 10 million gallons of water per day (MGD) from the Catawba River at all times, by significantly limiting withdrawals during times of drought. The agreement limits withdrawals to 6 MGD during times of most severe drought, or �exceptional� drought; 7 MGD during �extreme� drought; 8.5 MGD during �severe� drought; and 9 MGD during �moderate� drought. Further, the agreement restricts Concord and Kannapolis from withdrawing more than 3 MGD from the Catawba until July 1, 2015, and after they first are withdrawing 5 MGD from the Yadkin River.

Educational and business leaders want todays students both to master school subjects and to excel in areas such as problem solving, critical thinking, and communication

Dr. Leila Ebrahimpoor, dentist in Ottawa, ON, is excited to celebrate her 5th year with her dental practice after transfer.

FonePaw WhatsApp Transfer:Transfer WhatsApp Data Between Android and iOS

Multinational companies are generally aware of data transfer laws, but smaller ones just embarking on looking beyond country borders may not be.

The CL0P Ransomware Group, also known as TA505, has exploited zero-day vulnerabilities across a series of file transfer solutions since December 2020. File transfer solutions often contain sensitive information from a variety of organizations. This stolen information is used to extort victims to pay ransom demands. In 2023, CL0P claimed credit for the exploitation of vulnerabilities in both Fortra’s GoAnywhere Managed File Transfer (MFT) and Progress Software’s MOVEit Transfer solutions.

Research conducted as part of security audits has revealed additional vulnerabilities. This dashboard contains a list of vulnerabilities known to be exploited by the CL0P ransomware group as well as other vulnerabilities that could be leveraged by CL0P and other threat actors. Operations teams can use this data to identify the assets affected by the associated CVEs targeted by the CL0P ransomware group. The following Nessus plugins identify the affected vulnerabilities:

•  90190: Progress MOVEit Transfer Installed (Windows)
• 176735: Progress MOVEit Transfer Web Interface Detection
• 176736: Progress MOVEit Transfer FTP Detection
• 176567: Progress MOVEit Transfer
• 177371: Progress MOVEit Transfer Critical Vulnerability (June 15, 2023)

The dashboard and its components are available in the Tenable.sc Feed, a comprehensive collection of dashboards, reports, assurance report cards and assets. The dashboard can be easily located in the Tenable Security Center Feed under the category Security Industry Trends.

The requirements for this dashboard are:

• Tenable Security Center 6.1.1
• Tenable Nessus 10.5.2

The Security Response Team (SRT) in Tenable Research digs into technical details and tests proof-of-concept attacks, when available, to ensure customers are fully informed of risks. The SRT also provides breakdowns for the latest vulnerabilities in the Tenable blog.

Tenable Research has posted the FAQ for MOVEit Transfer Vulnerabilities and CL0P Ransomware Gang blog post to provide the latest information about this threat.

Components

CL0P Ransomware Group MOVEit – This table displays assets that are vulnerable to recent targeted attacks by the CL0P Ransomware Group (aka TA505) related to Progress Software’s MOVEit Transfer solutions. The component specifically provides results for pluginIDs 90190, 176735, 176736, 176567, 177082, and 177371. These vulnerabilities are associated with a zero-day that is actively being exploited. The table displays the IP address, NetBIOS, DNS, and OS CPE of any identified vulnerable assets, and the Vulnerabilities severity bar.

CL0P Ransomware Group Fortra GoAnywhere MFT – This table displays assets that may be vulnerable to recent targeted attacks by the CL0P Ransomware Group (aka TA505) related to Fortra GoAnywhere Managed File Transfer (MFT). The component specifically provides results for pluginIDs 171845, 171558, 171771, and 113896. These vulnerabilities are associated with a zero-day that is actively being exploited. The table displays the IP address, NetBIOS, DNS, OS CPE of any identified vulnerable assets, and the Vulnerabilities severity bar. 

CL0P Ransomware Group Accellion File Transfer – This table displays assets that may be vulnerable to recent targeted attacks by the CL0P Ransomware Group (aka TA505) for CGI abuses related to Accellion Secure File Transfer. The component specifically provides results for pluginIDs 85007, 146927, and 154933. These vulnerabilities are associated with a zero-day that is actively being exploited by the CL0P Ransomware Group, also known as TA505. The table displays the IP address, NetBIOS, DNS, and OS CPE of any identified vulnerable assets, and the Vulnerabilities severity bars.

CL0P Ransomware Group Patched Assets – This table displays vulnerabilities that have been remediated related to recent targeted attacks by the CL0P Ransomware Group (aka TA505). The remediated vulnerabilities displayed are specifically related to the vulnerabilities related to Progress Software’s MOVEit Transfer solutions, Fortra GoAnywhere Managed File Transfer, and Accellion Secure File Transfer. These vulnerabilities are associated with a zero-day that is actively being exploited. The table displays the PluginID, Vulnerability Name, Plugin Family, Severity, and Total of remediated vulnerabilities.

The Forgiven Canvas Transfer Framed by Thomas Blackshear II is a(n) Open Edition. The Edition is Limited to Open Edition No Serial Number pcs

Diversified Heat Transfer (DHT) announced the launch of its new corporate brand strategy and website, www.dhtnet.com, that elevates the company’s corporate identity and supports the ongoing evolution of the brand.

 

The iFTS will be showcased alongside R.A Jones’ Criterion CLI-100 cartoner at PACK EXPO Las Vegas 2023.

Room 29, Parliament Buildings

Room 29, Parliament Buildings

ASTANA, 14 July 2016 – The introduction of the Pollutant Release and Transfer Register (PRTR) in Kazakhstan was the focus of a roundtable discussion organized in Astana today by the OSCE Programme Office in Astana in partnership with the Energy Ministry’s Information and Analytical Centre of Environment Protection and the UN Development Programme in Kazakhstan.

Some 80 representatives of the Aarhus Centres, regional and central government entities, environmental NGOs and private sector focused on recent changes in national environmental legislation, guiding rules in implementing PRTR, international best practices and the role of the Aarhus Centres in promoting PRTR in the regions.

Joldasov Zulfuhar, Deputy Chairperson of the Committee of Environmental Regulation, Control and State Inspection in the oil and gas sector of Kazakhstan’s Energy Ministry, said:  “Taking into account that environmental damage impacts all spheres of life, a state register of pollutant release and transfer is particularly relevant. We are convinced of the need to co-operate with all interested parties and consolidate our efforts in addressing the emerging issues in the field of environmental protection and sustainable development.”

Mirco Guenther, Deputy Head of the OSCE Programme Office in Astana, said: "PRTR management can lead to a significant reduction in environmental and social risks to promote a constructive dialogue between interested parties, as well as to achieve a balance of interests and protection of environmental rights of citizens. The OSCE Programme Office in Astana stands ready to support Kazakhstan’s initiative to comply fully with all their obligations under the Aarhus Convention."

The PRTR Protocol was adopted in 2003, in Kyiv, Ukraine and is a legally binding instrument that requires parties to establish publicly accessible registers containing information on the release and transfer of pollutants.

The event is part of the Programme Office’s longstanding efforts in promoting the international standards of the Aarhus Convention in Kazakhstan.

Related Stories

• OSCE promotes Central Asian Leadership Program for young environmental leaders
• OSCE supports water co-operation in southern Kazakhstan
• Seminar for defence lawyers on new approaches and techniques of legal defence

ASTANA, 14 July 2016 – The introduction of the Pollutant Release and Transfer Register (PRTR) in Kazakhstan was the focus of a roundtable discussion organized in Astana today by the OSCE Programme Office in Astana in partnership with the Energy Ministry’s Information and Analytical Centre of Environment Protection and the UN Development Programme in Kazakhstan.

Some 80 representatives of the Aarhus Centres, regional and central government entities, environmental NGOs and private sector focused on recent changes in national environmental legislation, guiding rules in implementing PRTR, international best practices and the role of the Aarhus Centres in promoting PRTR in the regions.

Joldasov Zulfuhar, Deputy Chairperson of the Committee of Environmental Regulation, Control and State Inspection in the oil and gas sector of Kazakhstan’s Energy Ministry, said:  “Taking into account that environmental damage impacts all spheres of life, a state register of pollutant release and transfer is particularly relevant. We are convinced of the need to co-operate with all interested parties and consolidate our efforts in addressing the emerging issues in the field of environmental protection and sustainable development.”

Mirco Guenther, Deputy Head of the OSCE Programme Office in Astana, said: "PRTR management can lead to a significant reduction in environmental and social risks to promote a constructive dialogue between interested parties, as well as to achieve a balance of interests and protection of environmental rights of citizens. The OSCE Programme Office in Astana stands ready to support Kazakhstan’s initiative to comply fully with all their obligations under the Aarhus Convention."

The PRTR Protocol was adopted in 2003, in Kyiv, Ukraine and is a legally binding instrument that requires parties to establish publicly accessible registers containing information on the release and transfer of pollutants.

The event is part of the Programme Office’s longstanding efforts in promoting the international standards of the Aarhus Convention in Kazakhstan.

Related Stories

• OSCE supports water co-operation in southern Kazakhstan
• OSCE Programme Office supports training for defence lawyers in Kazakhstan on the new criminal procedure legislation
• OSCE Programme Office supports public hearings on libel and slander legislation in Kazakhstan

The Seminoles have another transfer heading out of Tallahassee after the April 15 Garnet and Gold Showcase.

The spring portal opened April 15, and moves are expected to take place before the 15-day window closes.

Electromagnetic field strength inside and outside of electric vehicles using wireless power transfer technology

FIGI - DFS - Technical Report on Methodology for inter-operator and cross-border P2P money transfers

Los funcionarios registran sus peticiones en el concurso de traslados hartos de la inacción del Ejecutivo autonómico ante reclamaciones sin respuesta desde 2021. Comisiones Obreras (CCOO) denuncia la "sobrecarga de trabajo" de los empleados públicos y exige a San José medios para "un servicio penitenciario público de calidad Leer

Host Bob Leins, CPA® welcomes Marc Levine, Esquire. 

The post Estate planning without estate planning: How joint ownership and beneficiary designations transfer assets at your death first appeared on Federal News Network.

Manufacturers in the rail, marine, defence and household good sectors can now benefit from more than 25 years of automotive and aerospace quality excellence as G&P is undergoing a proactive diversification drive across adjacent sectors.

Officials say the United States has given its approval for the Netherlands and Denmark to deliver F-16s to Ukraine. The defense ministers of those two NATO countries announced the decision Friday. It is a major gain for Kyiv even though the fighter jets won’t have an impact any time soon on the almost 18-month war. It was not immediately clear when the first F-16s might enter the conflict. Denmark says it will hand over some of its F-16s only after receiving its new F-35 jet fighters, which are due to start arriving on Oct. 1. Officials have previously said that Ukrainian pilots will need six to eight months of training on the F-16s.

The post Ukraine will get F-16 fighter jets from the Dutch and Danes after the US agrees to allow transfers first appeared on Federal News Network.

What exactly is zombie deer disease? Find out how chronic wasting disease spreads and if it poses a threat to humans.

Location: Electronic Resource- 

Incorporate the Interbanks Funds Transfer as another means of secured payment for online purchases made on www.newlook.com.sg.

We have opened an new bank account at DBS bank. This it to facility local shoppers since POSB/DBS ATM machines POSB banks is available at most public places.

RiverStone International announced that the previously disclosed agreement with QBE to provide a Loss Portfolio Transfer reinsurance [LPT] for various QBE subsidiaries, including their Lloyd’s syndicates has closed after receiving all requisite approvals A spokesperson said, “RiverStone International today announced that the previously disclosed agreement with QBE to provide a Loss Portfolio Transfer reinsurance [LPT] […]

A 59-year-old minibus driver was arrested and passengers were transferred to another vehicle, with the incident going viral on social media as passengers posted images. A police spokesperson said, “Around 8:50 a.m. on Monday, August 5th, 2024 police officers had cause to stop a minibus driven by a 59-year-old male, on Middle Road Southampton. “Upon being […]

Chelse­a looks to add promising young talent to their team with new transfer targets emerging this summer. The­ club hopes..

The post Latest Transfer Targets: Two Palace Stars appeared first on Chelsea FC Blog.

Now one of the most influential teams in the world, Chelsea have always pushed the boundaries both on the field..

The post Pivotal Transfers Throughout Chelsea’s History appeared first on Chelsea FC Blog.

As the 2024 summer transfer window closes, Chelsea has made several key signings that could significantly impact the upcoming season...

The post Chelsea’s Summer 2024 Transfers: Key Signings and How They’ll Impact the New Season appeared first on Chelsea FC Blog.

Over 1,500 Android devices have been infected by a new strain of Android banking malware called ToxicPanda that allows threat actors to conduct fraudulent banking transactions. "ToxicPanda's main goal is to initiate money transfers from compromised devices via account takeover (ATO) using a well-known technique called on-device fraud (ODF)," Cleafy researchers Michele Roviello, Alessandro Strino

Craig B. Arnold has been named Princeton’s first University Innovation Officer and heads the new office.

Thirteen Princeton University faculty members were transferred to emeritus status in recent action by the Board of Trustees.

Check out the significant signings and departures in the Premier League, Scottish Premiership, EFL and Women's Super League.

When the Baby Boomers retire they are going to be taking their substantial knowledge with them. The younger generation to whom that knowledge should be transferred likes to consume video.  This has some very interesting implications for organizations that want to capture that knowledge, organize it, and make it easy for employees to find it and benefit from it.

Here is a link to a webcast on June 1 where Dan Rasmus, a technology strategist and author of Listening to the Future , will discuss the potential for video to serve as an all important medium for knowledge transfer and organizational learning.

Topics to be Covered:
• Knowledge Acquisition via Video
• Video as a Tool for Knowledge Management
• Use of Video or Operational Efficiency
• Practical Applications of Video for Learning in the Enterprise

Click here to register for the webcast

David A. Mitchell
Jun 1, 2006; 47:1118-1127
Thematic Reviews

M. Mahmood Hussain
Jan 1, 2003; 44:22-32
Reviews

AR Tall
Aug 1, 1993; 34:1255-1274
Reviews

John A. Glomset
Mar 1, 1968; 9:155-167
Reviews

CARM1 is a protein arginine methyltransferase (PRMT) that acts as a coactivator in a number of transcriptional programs. CARM1 orchestrates this coactivator activity in part by depositing the H3R17me2a histone mark in the vicinity of gene promoters that it regulates. However, the gross levels of H3R17me2a in CARM1 KO mice did not significantly decrease, indicating that other PRMT(s) may compensate for this loss. We thus performed a screen of type I PRMTs, which revealed that PRMT6 can also deposit the H3R17me2a mark in vitro. CARM1 knockout mice are perinatally lethal and display a reduced fetal size, whereas PRMT6 null mice are viable, which permits the generation of double knockouts. Embryos that are null for both CARM1 and PRMT6 are noticeably smaller than CARM1 null embryos, providing in vivo evidence of redundancy. Mouse embryonic fibroblasts (MEFs) from the double knockout embryos display an absence of the H3R17me2a mark during mitosis and increased signs of DNA damage. Moreover, using the combination of CARM1 and PRMT6 inhibitors suppresses the cell proliferation of WT MEFs, suggesting a synergistic effect between CARM1 and PRMT6 inhibitions. These studies provide direct evidence that PRMT6 also deposits the H3R17me2a mark and acts redundantly with CARM1.

The molecular mechanisms of reduced frataxin (FXN) expression in Friedreich's ataxia (FRDA) are linked to epigenetic modification of the FXN locus caused by the disease-associated GAA expansion. Here, we identify that SUV4-20 histone methyltransferases, specifically SUV4-20 H1, play an important role in the regulation of FXN expression and represent a novel therapeutic target. Using a human FXN–GAA–Luciferase repeat expansion genomic DNA reporter model of FRDA, we screened the Structural Genomics Consortium epigenetic probe collection. We found that pharmacological inhibition of the SUV4-20 methyltransferases by the tool compound A-196 increased the expression of FXN by ∼1.5-fold in the reporter cell line. In several FRDA cell lines and patient-derived primary peripheral blood mononuclear cells, A-196 increased FXN expression by up to 2-fold, an effect not seen in WT cells. SUV4-20 inhibition was accompanied by a reduction in H4K20me2 and H4K20me3 and an increase in H4K20me1, but only modest (1.4–7.8%) perturbation in genome-wide expression was observed. Finally, based on the structural activity relationship and crystal structure of A-196, novel small molecule A-196 analogs were synthesized and shown to give a 20-fold increase in potency for increasing FXN expression. Overall, our results suggest that histone methylation is important in the regulation of FXN expression and highlight SUV4-20 H1 as a potential novel therapeutic target for FRDA.

Mammalian Asn-linked glycans are extensively processed as they transit the secretory pathway to generate diverse glycans on cell surface and secreted glycoproteins. Additional modification of the glycan core by α-1,6-fucose addition to the innermost GlcNAc residue (core fucosylation) is catalyzed by an α-1,6-fucosyltransferase (FUT8). The importance of core fucosylation can be seen in the complex pathological phenotypes of FUT8 null mice, which display defects in cellular signaling, development, and subsequent neonatal lethality. Elevated core fucosylation has also been identified in several human cancers. However, the structural basis for FUT8 substrate specificity remains unknown.Here, using various crystal structures of FUT8 in complex with a donor substrate analog, and with four distinct glycan acceptors, we identify the molecular basis for FUT8 specificity and activity. The ordering of three active site loops corresponds to an increased occupancy for bound GDP, suggesting an induced-fit folding of the donor-binding subsite. Structures of the various acceptor complexes were compared with kinetic data on FUT8 active site mutants and with specificity data from a library of glycan acceptors to reveal how binding site complementarity and steric hindrance can tune substrate affinity. The FUT8 structure was also compared with other known fucosyltransferases to identify conserved and divergent structural features for donor and acceptor recognition and catalysis. These data provide insights into the evolution of modular templates for donor and acceptor recognition among GT-B fold glycosyltransferases in the synthesis of diverse glycan structures in biological systems.

Identification of antibody-binding epitopes is crucial to understand immunological mechanisms. It is of particular interest for allergenic proteins with high cross-reactivity as observed in the lipid transfer protein (LTP) syndrome, which is characterized by severe allergic reactions. Art v 3, a pollen LTP from mugwort, is frequently involved in this cross-reactivity, but no antibody-binding epitopes have been determined so far. To reveal human IgE-binding regions of Art v 3, we produced three murine high-affinity mAbs, which showed 70–90% coverage of the allergenic epitopes from mugwort pollen–allergic patients. As reliable methods to determine structural epitopes with tightly interacting intact antibodies under native conditions are lacking, we developed a straightforward NMR approach termed hydrogen/deuterium exchange memory (HDXMEM). It relies on the slow exchange between the invisible antigen-mAb complex and the free 15N-labeled antigen whose 1H-15N correlations are detected. Due to a memory effect, changes of NH protection during antibody binding are measured. Differences in H/D exchange rates and analyses of mAb reactivity to homologous LTPs revealed three structural epitopes: two partially cross-reactive regions around α-helices 2 and 4 as well as a novel Art v 3–specific epitope at the C terminus. Protein variants with exchanged epitope residues confirmed the antibody-binding sites and revealed strongly reduced IgE reactivity. Using the novel HDXMEM for NMR epitope mapping allowed identification of the first structural epitopes of an allergenic pollen LTP. This knowledge enables improved cross-reactivity prediction for patients suffering from LTP allergy and facilitates design of therapeutics.

Thibaut Bourgeois
Dec 11, 2020; 0:jlr.RA120000737v1-jlr.RA120000737
Research Articles

Aloïs Dusuel
Dec 9, 2020; 0:jlr.RA120000704v1-jlr.RA120000704
Research Articles