The goods train was carrying iron ore and derailed between Raghavapuram and Ramagundam, officials said. No casualties or injuries were reported in the incident.

Telangana will become the second Congress-ruled state after Karnataka to undertake caste census - an exercise that would continue from November 6 to November 30.

A container carrying several cars caught fire on the Hyderabad-Mumbai highway today, causing traffic disruptions.

A 17-year-old girl student of Rajiv Gandhi University of Knowledge Technologies (RGUKT) in Nirmal district of Telangana allegedly died by suicide on Monday, police said.

The Congress and BJP fight against each other across the country, but have a "strange love story" in Telangana, former state minister and Bharat Rashtra Samithi (BRS) leader KT Rama Rao told NDTV today

1. Telangana train accident: Goods train derails near Peddapalli. Check full list of cancelled, diverted trains today | Today News  Mint
2. Goods train derails in Telangana's Peddapalli; 20 trains cancelled, 10 diverted  The Economic Times
3. 11 coaches of goods train derail in Telangana  The Times of India
4. Goods train derailment in Telangana affects rail traffic between Delhi and Chennai  Telangana Today
5. Goods train derails in Telangana's Peddapalli; 30 trains cancelled, several diverted  The Hindu

Glioblastoma (GBM) is a disease of the whole brain, with infiltrative tumor cells protected by an intact blood-brain barrier (BBB). GBM has a poor prognosis despite aggressive treatment, in part due to the lack of adequate drug permeability at the BBB. Standard of care GBM therapies include radiation and cytotoxic chemotherapy that lead to DNA damage. Subsequent activation of DNA damage response (DDR) pathways can induce resistance. Various DDR inhibitors, targeting the key regulators of these pathways such as ataxia telangiectasia mutated and Rad3-related (ATR), are being explored as radio- and chemosensitizers. Elimusertib, a novel ATR kinase inhibitor, can prevent repair of damaged DNA, increasing efficacy of DNA-damaging cytotoxic therapies. Robust synergy was observed in vitro when elimusertib was combined with the DNA-damaging agent temozolomide; however, we did not observe improvement with this combination in in vivo efficacy studies in GBM orthotopic tumor-bearing mice. This in vitro–in vivo disconnect was explored to understand factors influencing central nervous system (CNS) distribution of elimusertib and reasons for lack of efficacy. We observed that elimusertib is rapidly cleared from systemic circulation in mice and would not maintain adequate exposure in the CNS for efficacious combination therapy with temozolomide. CNS distribution of elimusertib is partially limited by P-glycoprotein efflux at the BBB, and high binding to CNS tissues leads to low levels of pharmacologically active (unbound) drug in the brain. Acknowledging the potential for interspecies differences in pharmacokinetics, these data suggest that clinical translation of elimusertib in combination with temozolomide for treatment of GBM may be limited.

Finding regulatory violations in two private hospitals operating in the twin cities of Hyderabad and Secunderabad, the Telangana drugs control administration (DCA) has issued advisories to all the private hospitals in the state mandating strict obtainment of NDPS licence (NDPS Form II) from the DCA to purchase and sell NDPS drugs.

<p>In October 2024, China based Bio-Thera Solutions&nbsp;(Bio-Thera)&nbsp;and Hungary’s Gedeon Richter announced they have reached an exclusive commercialization and license agreement for BAT2206, a biosimilar candidate to&nbsp;Johnson &amp; Johnson’s Stelara (ustekinumab).</p>

IWMI researchers comment on the importance of preserving Colombo's wetland ecosystem as the city becomes more vulnerable to flooding.

The post From wastelands to wetlands: The fight to save Sri Lanka’s natural flood buffers first appeared on International Water Management Institute (IWMI).

Urvashi Rautela recently left fans in awe by showcasing her French-speaking skills.

A student of the Rajiv Gandhi University of Knowledge and Technologies (RGUKT), also known as the IIIT Basar, in Basar town of Telangana's Nirmal district, committed suicide on Monday.

Police in Telangana's Vikarabad district on Tuesday arrested 55 people in connection with an attack on district officials during a public hearing for the proposed 'Pharma Village'.

A 33-year-old woman died and 20 others were taken ill due to food poisoning after eating momos served by a street vendor in Hyderabad last week. Mayonnaise served with momos was also suspected to be contaminated.

The Telangana State Board of Intermediate Education has released the Intermediate Public Examinations 2017 on the official website. {image-26-1453819607-students-examination-27-1488170247.jpg www.careerindia.com}  When are the exams conducted?The examination will begin from March 1, 2017 with the Second Language paper 1 for the first

పార్టీ మారిన ఎమ్మెల్యేలకు సంబంధించి హైకోర్టు సింగిల్ బెంచ్ ఇచ్చిన తీర్పును సవాల్ చేస్తూ డివిజన్ బెంచ్ లో దాఖలు చేసిన పిటిషన్ పై వాదనలు ముగిశాయి. ఇరువురి తరఫు వాదనలు విన్న హైకోర్టు తీర్పును రిజర్వ్ చేసింది. గత అసెంబ్లీ ఎన్నికల్లో ఖైరతాబాద్ నుంచి దానం నాగేందర్, స్టేషన్ ఘన్ పూర్ నుంచి కడియం శ్రీహరి,

Berlin ; Boston : Walter De Gruyter, [2010]

Berlin ; Boston : De Gruyter, [2023]

München ; Wien : De Gruyter Oldenbourg, [2023]

Celebs have some fun on Holi.

Asks State government to adhere to quality norms

New Congress Govt to continue thrust on industrial growth with a focus on MSMEs

Inaugurated virtually by Prime Minister Narendra Modi, the drone service is part of a series of health projects designed to enhance access to essential services in remote and underserved areas

The Board is expected to help develop and grow the spice’s market in India, which controls over 62% share of the turmeric world trade

Govt prepared to extend necessary support to the company in expanding its oil palm and dairy businesses 

Reddy said that his aim is to make Telangana a “Trillion Dollar” economy

EESL reaches out to various stakeholders and top leadership as the delay in payment is causing financial strain for the company.

This decision comes as the existing contract with the current vendor, TerraCIS, is set to expire on November 30, 2024

‘80,000 government employees will be roped in for conducting the survey and they will be appropriately trained for it’

With summer drawing a blank, theatres want to save money by stopping screenings 

Farmers have reaped a bumper rabi harvest of 1 crore tonnes of paddy

Seven deaths and 150 positive cases have been reported since January 1

Revanth Reddy campaigned for Congress candidates in Mumbai

Traffic was disrupted on the Addanki-Narketpally highway as farmers stopped movement of the vehicles

Telangana CM lists the initiatives taken, exams conducted, jobs secured in the last 10 months