replication

Researchers rewarded for publishing null results and replication studies




replication

Cell studies suggest some repurposed drugs could block replication of SARS-CoV-2

The experiments follow up on an earlier study that identified 69 compounds that could disrupt possible interactions between viral and human proteins




replication

Cell studies suggest some repurposed drugs could block replication of SARS-CoV-2

The experiments follow up on an earlier study that identified 69 compounds that could disrupt possible interactions between viral and human proteins




replication

Tumor localization of oncolytic adenovirus assisted by pH-degradable microgels with JQ1-mediated boosting replication and PD-L1 suppression for enhanced cancer therapy

Biomater. Sci., 2020, 8,2472-2480
DOI: 10.1039/D0BM00172D, Paper
Haishi Qiao, Xingmei Chen, Qiming Wang, Junmei Zhang, Dechun Huang, Enping Chen, Hongliang Qian, Yinan Zhong, Qi Tang, Wei Chen
Illustration of pH-degradable microgels (MGs) for the simultaneous encapsulation of OA and JQ1 for an enhanced oncolytic viral treatment with JQ1-meidated boosting viral replication and PD-L1 suppression.
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replication

Ochre crayons or waste products? Replications compared with MSA ‘crayons’ from Sibudu Cave, South Africa




replication

Agent stops common cold virus replication

In cells, inhibitor created by fragment-based drug design prevents rhinovirus from reproducing