Trial MVA85A - monkey trials for a booster vaccine for BCG, developed by researchers at Oxford University, is the subject of an investigation published on bmj.com. Experts warn that today’s investigation is just one example of “a systematic failure” afflicting preclinical research and call for urgent action “to make animal research more fit for...

Introductory statement by Ms Christine Lagarde, President of the European Central Bank, and Mr Luis de Guindos, Vice-President of the European Central Bank, Frankfurt am Main, 30 April 2020.

Members of the public will now have the chance to put questions to the Government, as the daily Downing Street coronavirus briefing opens up for the first time.

Coronavirus: The symptoms

The Transport Secretary will lead Saturday's briefing

Where coronavirus came from, Australia's relationship with China, and the possibility of being able to jump on a plane to New Zealand were all canvassed by the PM in his latest press conference.

The Prime Minister and Chief Medical Officer urge people to download the tracing app to speed easing of restrictions, while another large support package to help keep aged care resident safe is announced.

"These archeological treasures are precious and protecting them preserves a rich history and heritage. That is why the Justice Department will use all of its tools to vigorously enforce the laws designed to safeguard the cultural heritage of Native Americans."

"We have two goals for our work in Indian Country. One is to find immediate solutions to bring down the crime rates, including homicide, drugs, and violence against children and women, and to put policies in place to help tribal communities make a difference for themselves. The other is to develop long term answers to the problems facing tribal communities."

"We will be relentless in our investigation of corporate and financial wrongdoing, and will not hesitate to bring charges, where appropriate, for criminal misconduct on the part of businesses and business executives."

"The U.S. financial system is built on trust and transparency. Our banks must know what payments they are processing and for whom. Credit Suisse’s decades-long scheme to flout the rules that govern our financial institutions robbed our system of the legitimacy that is fundamental to it success."

"The Department of Justice and our partners in the national security community have no higher priority than disrupting those attempts, and bringing those who plot them to justice."

"This report shows the success of our collaborative efforts to prevent, identify, and prosecute the most egregious instances of health care fraud," said Attorney General Holder.

"We are here to announce the results of Project Deliverance – a 22-month, bilateral investigation focused on the transportation infrastructure in the United States used by Mexican drug cartels to distribute illegal narcotics throughout our country and smuggle weapons and cash across the U.S.-Mexico border," said Attorney General Holder.

Last night, federal agents arrested Lee Bentley Farkas, the former chairman of Taylor, Bean & Whitaker Mortgage Corporation. He has been charged in a 16-count indictment in the Eastern District of Virginia.

"This operation began on March 1, and to date involved 1,215 criminal defendants nationwide, defendants who were allegedly responsible for more than $2.3 billion in losses," said Attorney General Holder.

"Today marks an important step forward in administering justice, in healing community wounds, in improving public safety, and in restoring public trust in this city’s police department," said Attorney General Holder.

"We are here to announce the results of the largest federal health care fraud takedown in our nation’s history: 94 people in four cities have been charged for their alleged participation in schemes to submit more than $251 million in false Medicare claims," said Attorney General Holder.

"The pharmaceutical manufacturer Allergan has agreed to plead guilty and pay $600 million to resolve serious criminal and civil fraud allegations," announced Assistant Attorney General West.

"This morning, federal agents began arresting 11 individuals on charges that they conspired over an approximately 19-month period to corrupt the legislative process in Alabama," said Assistant Attorney General Breuer.

"Today, the Department of Justice, along with seven state attorneys general, filed a civil antitrust lawsuit in the Eastern District of New York challenging rules that Visa, MasterCard and American Express have put in place that prevent merchants from providing discounts to consumers."

"Today I’m pleased to be joined by the United States Attorney for the District of Puerto Rico, Rosa Emilia Rodriguez-Velez, and FBI Executive Assistant Director, Shawn Henry, to announce the results of Operation Guard Shack – the largest police corruption investigation in FBI history."

"Today’s charges mark the first time that HEAT’s Medicare Fraud Strike Force has indicted a corporate entity for Medicare fraud," said Assistant Attorney General Breuer.

"In addition to the arrests and criminal charges that Assistant Attorney General Breuer announced, we are also announcing that we have obtained a Temporary Restraining Order freezing the assets of four corporate entities," said Assistant Attorney General West.

"Every year, health care fraud costs American taxpayers billions of dollars and undermines the integrity of the health care programs on which so many of us depend," said Assistant Attorney General West.

"We are pleased to announce an important step in our ongoing efforts to protect the interests and safety of consumers, to ensure the strength of our markets, and to safeguard the intellectual property rights of innovators and entrepreneurs."

"Over the last two years, the Justice Department—in close collaboration with the Department of Health and Human Services—has made cracking down on health care fraud a top priority. Today, we announce the latest results of those efforts."

"Today, more than 800 federal, state and local law enforcement officials have arrested over 110 individuals, including dozens of La Cosa Nostra members and associates."

"The Departments of Justice and HHS have a long history of working together in this fight against health care fraud. While we know that most health care dollars are spent on healing sick Americans and most companies and providers work hard to play by the rules, we also know that too much money is lost to fraud and abuse. So, we have been fighting back together, on behalf of American taxpayers and patients."

"I am pleased to be here today with my friend, U.S. Attorney Birotte, and our law enforcement partners to announce these indictments, and the arrest of more than 80 members and associates of transnational organized crime groups, including a particularly powerful one based here in California."

"As today’s arrests prove, the federal government is working aggressively to pursue health care criminals around the country and to bring offenders to justice."

I am here to announce the U.S. government’s latest actions to ensure safety along our Southwest border, to seek justice for victims of violent crime in this region, and to weaken dangerous criminal organizations currently operating in Mexico and the United States – including the international gang known as “Barrio Azteca.”

From the very first day of this investigation, prosecutors from the Justice Department’s Criminal Division and the U.S. Attorney’s Office in El Paso have worked around-the-clock with our law enforcement partners in Mexico and the United States to find those responsible for these heinous crimes and bring them to justice.

"The Justice Department opened its investigation of the New Orleans Police Department last year with a single mission: to work with all stakeholders to build a world class police force," said Assistant Attorney General Perez.

"Unfortunately, our conclusions reveal that many NOPD officers have failed to live up to what we rightfully expect from our law enforcement officers," said Deputy Attorney General Cole.

"the Civil Rights Division, along with the U.S. Attorney’s Office, conducted a preliminary inquiry and concluded that it would be necessary and appropriate to begin a formal civil pattern or practice investigation," said Assistant Attorney General Perez.

"Today, a 50-count superseding indictment was unsealed charging 13 leaders, members and associates of the Philadelphia La Cosa Nostra Family with crimes that spanned more than a decade."

"Effective, accountable policing is critical for any healthy community, and we are here today because we all share the goal of ensuring that the Portland Police Bureau is the best law enforcement agency that it can be."

The Department of Justice, through our United States Attorneys’ Offices and the Civil Division’s Office of Consumer Protection Litigation, is investigating and prosecuting dozens of cases against these so-called “notarios,” said Assistant Attorney General West.

"Today’s agreement will bring Delaware into compliance with the ADA and the Olmstead decision by building a comprehensive, community-based mental health system," said Assistant Attorney General Perez.

"And as Attorney General Eric Holder has often said, two of the Department’s highest priorities are fighting financial fraud and protecting our most vulnerable citizens, such as our elder citizens," said Assistant Attorney General West.

"This successful operation marks another step forward in our work to protect children across, and beyond, our country," said Attorney General Holder.

"We will continue our strategy of targeting the most sophisticated child exploitation networks, at home and abroad, and sending the message loud and clear that no matter how savvy online predators think they are, we will find them, dismantle their networks, and bring them to justice," said Assistant Attorney General Breuer.

"Regrettably, as we have seen here in New Mexico and across the nation, the need for aggressive enforcement remains," said Assistant Attorney General Perez.

"T-Mobile has been an important source of competition among the national carriers through innovation and quality enhancements," said Acting Assistant Attorney General Pozen.

"The Department filed its lawsuit because we believe the combination of AT&T and T-Mobile would result in tens of millions of consumers all across the United States facing higher prices, fewer choices and lower quality products for their mobile wireless services," said Deputy Attorney General Cole.

"We are pleased to announce the results of a nationwide takedown, by Medicare Fraud Strike Force operations in eight cities, that has resulted in charges against 91 defendants for their alleged participation in Medicare fraud schemes involving nearly $300 million in false billings," said Attorney General Holder.

"The indictments announced today serve as a powerful reminder that Medicare fraud is a nationwide problem," said Assistant Attorney General Breuer.

"As outlined in our findings report, we found reasonable cause to believe that PRPD engages in a pattern and practice of unconstitutional and/or unlawful conduct in three areas," said Assistant Attorney General Perez.

"The settlement requires Regal Stone Limited and Fleet Management Limited to pay more than $44 million for natural resource damages and penalties, and to reimburse the government entities for response costs incurred as a result of the spill," said Assistant Attorney General Moreno.