biotechnology

On Trial: Agricultural Biotechnology in Africa

21 July 2014

Rob Bailey

Former Research Director, Energy, Environment and Resources

Robin Willoughby
David Grzywacz 

Increasing agricultural productivity and adapting farming to climate change are central to Africa’s development prospects. There are important opportunities to enhance yields and increase resilience through the adoption of improved crop varieties. In some cases, biotechnology, and in particular genetic modification (GM), offers advantages over conventional plant-breeding approaches. Accordingly there are a various projects under way to develop new GM varieties for African farmers, ranging from drought-resistant maize to varieties of cassava, banana, sorghum, cowpea and sweet potato with resistance to pests and disease.

In addition to government funds, these projects have also attracted the support of influential donor agencies and philanthropic foundations. However, despite the expenditure of considerable resources, the potential of GM in Africa is not being realized. So far no GM trait developed for African farmers has been put to use.

Multiple barriers inhibit the development and adoption of pro-poor GM varieties in Africa. On the demand side, farmers may be reluctant to adopt GM varieties owing to a lack of export opportunities and distrust of the technology among local consumers. Farmers may also be concerned about exploitation by transnational seed companies (despite the fact that development of new GM technologies in Africa is dominated by the public sector). On the supply side, donor funding struggles to match the long timescales of research and development, while incentives among research scientists may be poorly aligned with farmer outcomes. Non-existent, poorly functioning or overly punitive regulatory regimes discourage investment.

The most important barriers – such as regulatory constraints, consumer distrust and weak farmer demand – must be understood in the context of wider social and political dynamics surrounding GM, typified by misinformation, polarized public discourse, and dysfunctional and opportunistic politics. The result is most GM projects becoming ‘stuck’ at the field trial stage without ever progressing to release. This ‘convenient deadlock’ of continual field trials allows governments to manage political risks by effectively balancing the demands of pro-GM and anti-GM lobbies – proponents of GM have a pipeline of technologies, while opponents are appeased by the failure of any to gain approval. The disabling socio-political environment for GM development in Africa greatly reduces the efficacy of investment in this technology.

This has two important implications. First, technology development needs to be located within a wider project of transformation that engages key actors – most notably politicians, policy-makers and farmers – as stakeholders from the outset, and includes strategies to address multiple demand- and supply-side barriers. Second, successful adoption is more likely in countries with less disabling political conditions, characterized by lower levels of consumer distrust and opposition, genuine farmer demand and demonstrable commitment from government. Focusing efforts and resources on a small number of ‘best bet’ countries will also allow donors and technology providers to support more ambitious, transformational projects led by national governments.




biotechnology

Nanomaterials and environmental biotechnology

9783030345440 (electronic bk.)




biotechnology

Microalgae biotechnology for food, health and high value products

9789811501692 (electronic bk.)




biotechnology

Grand challenges in fungal biotechnology

9783030295417 (electronic bk.)




biotechnology

Current developments in biotechnology and bioengineering : resource recovery from wastes

0444643222




biotechnology

Bioremediation and biotechnology : sustainable approaches to pollution degradation

9783030356910 (electronic bk.)




biotechnology

Global biotechnology FDI on the rise

Global FDI in the biotechnology sector has witnessed year-on-year increase since 2015.




biotechnology

Multifunctional Acidocin 4356 Combats Pseudomonas aeruginosa through Membrane Perturbation and Virulence Attenuation: Experimental Results Confirm Molecular Dynamics Simulation [Biotechnology]

A longstanding awareness in generating resistance to common antimicrobial therapies by Gram-negative bacteria has made them a major threat to global health. The application of antimicrobial peptides as a therapeutic agent would be a great opportunity to combat bacterial diseases. Here, we introduce a new antimicrobial peptide (~8.3 kDa) from probiotic strain Lactobacillus acidophilus ATCC 4356, designated acidocin 4356 (ACD). This multifunctional peptide exerts its anti-infective ability against Pseudomonas aeruginosa through an inhibitory action on virulence factors, bacterial killing, and biofilm degradation. Reliable performance over tough physiological conditions and low hemolytic activity confirmed a new hope for the therapeutic setting. Antibacterial kinetic studies using flow cytometry technique showed that the ACD activity is related to the change in permeability of the membrane. The results obtained from molecular dynamic (MD) simulation were perfectly suited to the experimental data of ACD behavior. The structure-function relationship of this natural compound, along with the results of transmission electron microscopy analysis and MD simulation, confirmed the ability of the ACD aimed at enhancing bacterial membrane perturbation. The peptide was effective in the treatment of P. aeruginosa infection in mouse model. The results support the therapeutic potential of ACD for the treatment of Pseudomonas infections.

IMPORTANCE Multidrug-resistant bacteria are a major threat to global health, and the Pseudomonas bacterium with the ability to form biofilms is considered one of the main causative agents of nosocomial infections. Traditional antibiotics have failed because of increased resistance. Thus, finding new biocompatible antibacterial drugs is essential. Antimicrobial peptides are produced by various organisms as a natural defense mechanism against pathogens, inspiring the possible design of the next generation of antibiotics. In this study, a new antimicrobial peptide was isolated from Lactobacillus acidophilus ATCC 4356, counteracting both biofilm and planktonic cells of Pseudomonas aeruginosa. A detailed investigation was then conducted concerning the functional mechanism of this peptide by using fluorescence techniques, electron microscopy, and in silico methods. The antibacterial and antibiofilm properties of this peptide may be important in the treatment of Pseudomonas infections.




biotechnology

USPTO Biotechnology/Chemical/Pharmaceutical Customer Partnership Meeting

Biotechnology/Chemical/Pharmaceutical Customer Partnership   Wednesday, June 8, 2011 Meeting  Madison Auditorium   Starting Time of 10:00 AM  United States Patent and Trademark Office Alexandria, Virginia  600 Dulany Street, Alexandria, VA,  Accessing the event: Double click on the link below (or copy it into your internet browser) https://uspto.connectsolutions.com/r80345544/ Click here   for detailed login instructions in MS Word.   […]




biotechnology

Vir Biotechnology, Alnylam Identify VIR-2703 Candidate For Treatment Of COVID-19

Vir Biotechnology, Inc. (VIR) and Alnylam Pharmaceuticals, Inc. (ALNY) announced Monday that they have selected a development candidate (DC) for VIR-2703 (ALN-COV), an investigational RNAi therapeutic targeting the SARS-CoV-2 (COVID-19) genome.




biotechnology

Nature Biotechnology




biotechnology

20,000 Gallons of Renewable Fuel Per Acre: Joule Biotechnology Lifts Veil on Direct CO2 to Fuel Process

If there's a holy grail of liquid renewable fuels it might look something like this: High yield per acre, doesn't negatively impact water supplies, doesn't compete with food crops, and is cost-competitive with fossil




biotechnology

Amgen Foundation Announces New $4 Million Commitment to Bring Hands-On Biotechnology Labs to Secondary School Students - The Amgen Biotech Experience in the classroom

The Amgen Biotech Experience empowers teachers to bring biotechnology into their classrooms to spark students’ love of science and features a hands-on curriculum that introduces students to the excitement of scientific discovery.




biotechnology

Mega Hiring Fresher Biotechnology Candidates

Company: Nanu India Recruitment Co
Qualification: Bachelor of Science (B.Sc), Masters in Technology (M.Tech/M.E/M.Sc)
Experience: 0 to 1
Salary: 1.80 to 3.50
location: Mumbai City, Navi Mumbai, Thane
Ref: 24822451
Summary: Mega Hiring Fresher Biotechnology Candidates.




biotechnology

HOW TO MAKE CAREER IN BIOTECHNOLOGY

In simplest words, Biotechnology is based on biology. It is all around us and is already a big part of our lives. It is used in developing breakthrough products and technologies that help improving the health of the planet, using...




biotechnology

Future Prospects for Industrial Biotechnology

This book examines international drivers, enabling technologies fast-tracking industrial biotechnology, industry trends, some products appearing on the market, industry structure and finance, and policy measures and trends. It examines separately biofuels, biobased chemicals and bioplastics.




biotechnology

Global Forum on Biotechnology: The Evolving Promise of the Life Sciences

The OECD and the ESRC Genomics Policy & Research Forum jointly organised a one-day Forum on 12 November 2012 in Paris. The event was both retrospective and forward-looking. The forum concluded that the promise of biotechnology is not set but evolves with fresh scientific knowledge, novel laws and regulations. The future of biotechnology needs to also integrate social and cultural dimensions.




biotechnology

Marine Biotechnology: Enabling Solutions for Ocean Productivity and Sustainability

This book discusses scientific and technological tools at the centre of a renewed interest in marine biotechnology that is contributing to a new bioeconomy sector in many countries and offering potential new solutions to global challenges.




biotechnology

Marine biotechnology: Definitions, infrastructures and directions for innovation

Several countries have been setting up strategic roadmaps to support marine biotechnologies that could drive innovation and help address the global sustainability goals of food, energy, and health. This report identifies and begins to address challenges facing cooperation on marine biotechnology across countries.




biotechnology

Key biotechnology indicators

Statistics on biotechnology firms, biotechnology R&D (including public sector expenditures), biotech applications and patents.




biotechnology

Revised proposal for the revision of the statistical definitions of biotechnology and nanotechnology

This document revises the OECD's statistical definition of biotechnology, which had last been reviewed in 2008, and proposes the adoption of a statistical definition of nanotechnology in the same format.




biotechnology

GlaxoSmithKline links up with Vir Biotechnology to find a vaccine

Glaxo said it would invest more than £200m in the US company and that they would initially focus on speeding up development of Vir's antibody drugs, which could be used to treat Covid-19.




biotechnology

How International Biotechnology Trust invests in medicine's future

Biotechnology lies at the intersection of a growing need for healthcare and treatments tailored to patients. Ailsa Craig, of International Biotechnology Trust, explains how it invests.




biotechnology

Systems and synthetic biotechnology for production of nutraceuticals [Electronic book] / Long Liu, Jian Chen, editors.

Singapore : Springer, c2019.




biotechnology

Nanobiotechnology in neurodegenerative diseases [Electronic book] / Mahendra Rai, Alka Yadav, editors.

Cham : Springer, c2019.




biotechnology

Grand challenges in algae biotechnology [Electronic book] / Armin Hallmann, Pabulo H. Rampelotto, editors.

Cham, Switzerland : Springer, [2019]




biotechnology

Bacilli and agrobiotechnology : phytostimulation and biocontrol. Volume 2 [Electronic book] / M. Tofazzal Islam, M. Mahfuz Rahman, Piyush Pandey, Michael Henry Boehme, Geert Haesaert, editors.

Cham, Switzerland : Springer, [2019]




biotechnology

Nanomaterials and environmental biotechnology Indu Bhushan, Vivek Kumar Singh, Durgesh Kumar Tripathi, editors

Online Resource




biotechnology

Proceed with caution?: concept and application of the precautionary principle in nanobiotechnology / edited by Rainer Paslack, Johann S. Ach, Beate Lüttenberg, Klaus-Michael Weltring

Hayden Library - T174.7.P665 2012




biotechnology

Chasing Captain America: how advances in science, engineering, and biotechnology will produce a superhuman / E. Paul Zehr ; foreword by Simon Whitfield ; afterword by Nicole Stott

Hayden Library - QH442.Z44 2018




biotechnology

Advances in Animal Biotechnology

Online Resource




biotechnology

Introduction to pharmaceutical biotechnology. Saurabh Bhatia and Divakar Goli

Online Resource




biotechnology

Introduction to pharmaceutical biotechnology. Saurabh Bhatia

Online Resource




biotechnology

Introduction to pharmaceutical biotechnology. Saurabh Bhatia and Satish Sardana, Tanveer Naved

Online Resource




biotechnology

Plant Biotechnology Persa [electronic journal].




biotechnology

Statistics for biotechnology process development / edited by Todd Coffey, Harry Yang

Hayden Library - TP248.25.A96 S73 2018




biotechnology

Multifaceted Protocol in Biotechnology / Azura Amid [and 3 others], editors

Online Resource




biotechnology

Nanobiotechnology in food: concepts, applications and perspectives / Hoda Jafarizadeh-Malmiri, Zahra Sayyar, Navideh Anarjan, Aydin Berenjian

Online Resource




biotechnology

2018 International Conference on Biotechnology and Bioengineering (8th ICBB): conference date, 24-26 October 2018: location, Budapest, Hungary / editors, Antonio Trincone and Mingfu Gong

Online Resource




biotechnology

Recent advancement in white biotechnology through fungi. Ajar Nath Yadav, Shashank Mishra, Sangram Singh, Arti Gupta, editors

Online Resource




biotechnology

Yeasts in biotechnology and human health: physiological genomic approaches / Isabel Sá-Correia, editor

Online Resource




biotechnology

Advances in plant & microbial biotechnology / Rita Kundu, Rajiv Narula, editors

Online Resource




biotechnology

Pharmaceutical biotechnology: fundamentals and applications / Daan J. A. Crommelin, Robert D. Sindelar, Bernd Meibohm, editors

Online Resource




biotechnology

Recent advancement in white biotechnology through fungi. Ajar Nath Yadav, Sangram Singh, Shashank Mishra, Arti Gupta, editors

Online Resource




biotechnology

Plant biotechnology and medicinal plants: periwinkle, milk thistle and foxglove / Mohamed Ramadan Rady

Online Resource




biotechnology

Biotechnology fundamentals / Firdos Alam Khan

Online Resource




biotechnology

Essentials of marine biotechnology / Se-Kwon Kim

Online Resource




biotechnology

Recent Advancement in White Biotechnology Through Fungi. Ajar Nath Yadav, Sangram Singh, Shashank Mishra, Arti Gupta, editors

Online Resource




biotechnology

Plant biotechnology: progress in genomic era / S. M. Paul Khurana, Rajarshi Kumar Gaur, editors

Online Resource




biotechnology

Grand challenges in fungal biotechnology Helena Nevalainen, editor

Online Resource