aggregation Detection of Protein Aggregation in Live Plasmodium Parasites [Pharmacology] By aac.asm.org Published On :: 2020-04-13T08:15:30-07:00 The rapid evolution of resistance in the malaria parasite to every single drug developed against it calls for the urgent identification of new molecular targets. Using a stain specific for the detection of intracellular amyloid deposits in live cells we have detected the presence of abundant protein aggregates in Plasmodium falciparum blood stages and female gametes cultured in vitro, in the blood stages of mice infected by Plasmodium yoelii, and in the mosquito stages of the murine malaria species Plasmodium berghei. Aggregated proteins could not be detected in early rings, the parasite form that starts the intraerythrocytic cycle. A proteomics approach was followed to pinpoint actual aggregating polypeptides in functional P. falciparum blood stages, which resulted in the identification of 369 proteins, with roles particularly enriched in nuclear import-related processes. Five aggregation-prone short peptides selected from this protein pool exhibited different aggregation propensity according to Thioflavin-T fluorescence measurements, and were observed to form amorphous aggregates and amyloid fibrils in transmission electron microscope images. The results presented suggest that generalized protein aggregation might have a functional role in malaria parasites. Future antimalarial strategies based on the upsetting of the pathogen's proteostasis and therefore affecting multiple gene products could represent the entry to new therapeutic approaches. Full Article
aggregation Five Companies You’ve Definitely Heard of Join Up to Buy Solar Energy in Aggregation Deal By feedproxy.google.com Published On :: 2019-01-17T15:32:08Z It’s hard to find a common thread between the business models of Gap, Bloomberg, Cox, Salesforce and Workday but today they are announcing that they all have one big thing in common: their desire to clean up their organizations’ energy supply by using renewable energy. Full Article Energy Efficiency News Utility Scale Solar SolarFeatured
aggregation [ASAP] Thiosemicarbazone Derivatives as Inhibitors of Amyloid-ß Aggregation: Effect of Metal Coordination By feedproxy.google.com Published On :: Tue, 05 May 2020 04:00:00 GMT Inorganic ChemistryDOI: 10.1021/acs.inorgchem.0c00467 Full Article
aggregation [ASAP] A Spectroscopic Marker for Structural Transitions Associated with Amyloid-ß Aggregation By feedproxy.google.com Published On :: Thu, 30 Apr 2020 04:00:00 GMT BiochemistryDOI: 10.1021/acs.biochem.0c00113 Full Article
aggregation Precise Tracking and Modulating Aggregation Structures of Conjugated Copolymers in Solutions By feeds.rsc.org Published On :: Polym. Chem., 2020, Accepted ManuscriptDOI: 10.1039/D0PY00456A, PaperZi-Yuan Wang, Ze-Fan Yao, Yang Lu, Li Ding, Zi-Di Yu, Hao-Yang You, Xin-Yi Wang, Yang-Yang Zhou, Lin Zou, Jie-Yu Wang, Jian PeiThe effects of the backbone shape of the conjugated polymers on the aggregation features in solutions, and further on the morphology in solid states are rarely reported. Herein, four copolymers,...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
aggregation Aggregation-induced emission luminogens for RONS sensing By pubs.rsc.org Published On :: J. Mater. Chem. B, 2020, 8,3357-3370DOI: 10.1039/C9TB02310K, Review ArticleJun Dai, Chong Duan, Yu Huang, Xiaoding Lou, Fan Xia, Shixuan WangThe development of AIE bioprobes for RONS sensing in living systems is now summarized. We discuss some representative examples of AIEgen based bioprobes in terms of their molecular design, sensing mechanism and sensitive sensing in vitro and in vivo.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
aggregation Human serum albumin-based doxorubicin prodrug nanoparticles with tumor pH-responsive aggregation-enhanced retention and reduced cardiotoxicity By pubs.rsc.org Published On :: J. Mater. Chem. B, 2020, 8,3939-3948DOI: 10.1039/D0TB00327A, PaperBoya Zhang, Shiyu Wan, Xinyu Peng, Mingying Zhao, Sai Li, Yuji Pu, Bin HeA nano-assembly of pH-sensitive doxorubicin prodrug and human serum albumin shows tumor pH-responsive aggregation, enhanced tumor retention and reduced cytotoxicity.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
aggregation Chinese News Aggregation App Targets $3 Billion U.S. IPO By www.rss-specifications.com Published On :: Wed, 18 Apr 2018 09:51:07 -0400 Qu Toutiao, which means Fun Headlines in Chinese, is reportedly making its own fun headlines these days, telling sources that it is eyeing an initial public offering that could value it as high as $3 billion. If successful, it would be an extraordinary valuation for a company, a news and video aggregation mobile app popular in mostly rural areas of China, that was launched less than 2 years ago. The company is considering an IPO in New York as soon as early this year, people familiar with the matter told Bloomberg News. complete article Full Article
aggregation Techmeme Brings Its Aggregation Formula to a Daily Podcast By www.rss-specifications.com Published On :: Fri, 20 Apr 2018 09:56:02 -0400 Techmeme, the online aggregator of record for technology industry news, is adding some audio in the form of a podcast: the Techmeme Ride Home. Beginning today, the site’s new podcast will appear at 5 p.m. every weekday. Over 20 minutes, host Brian McCullough (from The Internet History podcast) will summarize the day’s top tech news and commentary from around the web and social media. Plain-vanilla news aggregation is unusual in podcasts. Even in tech, podcasts tend to be personality-driven, more often involving hosts providing commentary on the big news of the week rather than just the news itself. McCullough thinks Techmeme can offer something different. complete article Full Article
aggregation [ASAP] Aggregation-Dependent Photoreactive Hemicyanine Assembly as a Photobactericide By feedproxy.google.com Published On :: Fri, 08 May 2020 04:00:00 GMT ACS Applied Materials & InterfacesDOI: 10.1021/acsami.0c03894 Full Article
aggregation Smart meter data analytics: electricity consumer behavior modeling, aggregation, and forecasting / Yi Wang, Qixin Chen, Chongqing Kang By library.mit.edu Published On :: Sun, 12 Apr 2020 09:09:06 EDT Online Resource Full Article
aggregation Effect of freeze/thaw on aggregation and transport of nano-TiO2 in saturated porous media By pubs.rsc.org Published On :: Environ. Sci.: Nano, 2020, Advance ArticleDOI: 10.1039/D0EN00008F, PaperJeffrey M. Farner, Jacopo De Tommaso, Heather Mantel, Rachel S. Cheong, Nathalie TufenkjiResearch has focused on nanoparticle (NP) aggregation and transport behavior in saturated granular porous media, but few studies have looked at the effect that temperature variability associated with winter conditions will have on engineered NPs.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
aggregation Privacy-enhancing aggregation techniques for smart grid communications / Rongxing Lu By prospero.murdoch.edu.au Published On :: Lu, Rongxing, author Full Article
aggregation Synthesis and aggregation behaviour of single-chain, 1,32-alkyl-branched bis(phosphocholines) – part 2: lateral chain length triggers self-assembling from sheets to fibres to vesicles By feeds.rsc.org Published On :: Org. Biomol. Chem., 2020, Advance ArticleDOI: 10.1039/D0OB00534G, PaperKai Gruhle, Max Tuchtenhagen, Sindy Müller, Gerd Hause, Annette Meister, Simon DrescherThe synthesis of six single-chain, alkyl-branched bolalipids and first investigations of the lyotropic behaviour of these lipids are reported.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
aggregation Hyperbolic and kinetic models for self-organised biological aggregations: a modelling and pattern formation approach / Raluca Eftimie By library.mit.edu Published On :: Sun, 17 Feb 2019 13:12:16 EST Online Resource Full Article
aggregation Efficient near-infrared photosensitizer with aggregation-induced emission characteristics for mitochondria-targeted and image-guided photodynamic cancer therapy By pubs.rsc.org Published On :: Mater. Chem. Front., 2020, Advance ArticleDOI: 10.1039/D0QM00170H, Research ArticleHanxiao Yang, Jiabao Zhuang, Nan Li, Yue Li, Shiyu Zhu, Jiaxin Hao, Jiayao Xin, Na ZhaoA highly efficient near-infrared photosensitizer with aggregation-induced emission characteristics was developed for mitochondria-targeted and image-guided photodynamic cancer therapy.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
aggregation The origin of the unusual red-shifted aggregation-state emission of triphenylamine-imidazole molecules: excimers or a photochemical reaction? By pubs.rsc.org Published On :: Mater. Chem. Front., 2020, 4,1411-1420DOI: 10.1039/C9QM00737G, Research ArticleJin Liu, Jianai Chen, Yujie Dong, Yue Yu, Shitong Zhang, Jianli Wang, Qingbao Song, Weijun Li, Cheng ZhangRevealing the actual origin of the unusual red-shifted aggregation-state emission of triphenylamine-imidazole molecules: is the photochemical reaction rather than the excimers.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
aggregation Origin of aggregation-induced enhanced emission: role of pseudo-degenerate electronic states of excimers formed in aggregation phases By pubs.rsc.org Published On :: J. Mater. Chem. C, 2020, Advance ArticleDOI: 10.1039/C9TC07067B, PaperWataru Ota, Ken Takahashi, Kenji Higashiguchi, Kenji Matsuda, Tohru SatoThe origin of aggregation-induced enhanced emission (AIEE) is investigated considering cyano-substituted 1,2-bis(pyridylphenyl)ethene (CNPPE) as an example.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
aggregation Aggregation-State engineering and emission switching in D-A-D' AIEgens featuring dual emission and high contrast MCL By pubs.rsc.org Published On :: J. Mater. Chem. C, 2020, Accepted ManuscriptDOI: 10.1039/D0TC01733G, PaperJi-Hua Tan, Wen-Cheng Chen, Shao-Fei Ni, Zhipeng Qiu, yingying zhan, Zhiwen Yang, Jingwen Xiong, Chen Cao, Yanping Huo, Chun-Sing LeeThermally activated delayed fluorescence (TADF) and room-temperature phosphorescence (RTP) have attracted much recent attention for their capabilities to utilize triplet excitons for emission. Herein, we demonstrate a strategy for switching...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
aggregation [ASAP] Aggregation-Induced Emission Active Polyacrylates via Cu-Mediated Reversible Deactivation Radical Polymerization with Bioimaging Applications By feedproxy.google.com Published On :: Fri, 08 May 2020 04:00:00 GMT ACS Macro LettersDOI: 10.1021/acsmacrolett.0c00281 Full Article
aggregation [ASAP] Interaction Volume Is a Measure of the Aggregation Propensity of Amyloid-ß By feedproxy.google.com Published On :: Wed, 06 May 2020 04:00:00 GMT The Journal of Physical Chemistry LettersDOI: 10.1021/acs.jpclett.0c00922 Full Article
aggregation [ASAP] Sugar-Based Aggregation-Induced Emission Luminogens: Design, Structures, and Applications By feedproxy.google.com Published On :: Tue, 14 Apr 2020 04:00:00 GMT Chemical ReviewsDOI: 10.1021/acs.chemrev.9b00814 Full Article
aggregation [ASAP] Heteroaggregation between Charged and Neutral Particles By feedproxy.google.com Published On :: Mon, 04 May 2020 04:00:00 GMT LangmuirDOI: 10.1021/acs.langmuir.0c00667 Full Article
aggregation A single-ligand-protected Eu60−nGd(Tb)n cluster: a reasonable new approach to expand lanthanide aggregations By pubs.rsc.org Published On :: Inorg. Chem. Front., 2020, Advance ArticleDOI: 10.1039/D0QI00226G, Research ArticleXi-Ming Luo, Ning-Fang Li, Qing-Fang Lin, Jia-Peng Cao, Peng Yuan, Yan XuTwo fascinating configurations were obtained based on mixed-lanthanide conditions, abbreviated as mixed-Ln60. The synthesis provides a way to obtain similar metal-core Ln high-nuclearity clusters, breaking the ionic radius limitation.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
aggregation Exploiting cation aggregation in new magnesium amidohaloaluminate electrolytes for magnesium batteries By pubs.rsc.org Published On :: Inorg. Chem. Front., 2020, Advance ArticleDOI: 10.1039/C9QI01606F, Research Article Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Etienne V. Brouillet, Marco Amores, Serena A. Corr, Stuart D. RobertsonThe active species in magnesium electrolytes is regularly assigned as being the thermodynamically stable dinuclear [Mg2Cl3]+ cation. By deliberately targeting other implicated aggregates, their effect on Mg-ion battery performance is easily ascertained.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
aggregation Ruthenium(III) complexes containing thiazole-based ligands that modulate amyloid-β aggregation By feeds.rsc.org Published On :: Metallomics, 2020, 12,491-503DOI: 10.1039/D0MT00054J, PaperSamantha E. Huffman, Gideon K. Yawson, Samuel S. Fisher, Paige J. Bothwell, David C. Platt, Marjorie A. Jones, Christopher G. Hamaker, Michael I. WebbAlzheimer's Disease (AD) is a devastating neurodegenerative disorder where one of the commonly observed pathological hallmarks is extracellular deposits of the peptide amyloid-β (Aβ).The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
aggregation Diphenyl Diselenide Protects Caenorhabditis elegans Model for Huntington's Disease by Activation of Antioxidant Pathway and Decrease in Protein Aggregation By feeds.rsc.org Published On :: Metallomics, 2020, Accepted ManuscriptDOI: 10.1039/D0MT00074D, PaperFabiane Bicca Obetine Baptista, Marina Lopes Machado, Aline da Silva Franzen, Larissa Marafiga Cordeiro, Tassia da Silveira, Leticia Arantes, Félix A. A. SoaresHuntington’s disease (HD) is an autosomal dominant, progressive neurodegenerative disease with a distinct phenotype. It occurs due to a mutation in huntingtin (or IT19) gene with abnormal CAG repeat, leading...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
aggregation A high-throughput plasmonic tongue using an aggregation assay and nonspecific interactions: classification of taste profiles in maple syrup By feeds.rsc.org Published On :: Anal. Methods, 2020, Advance ArticleDOI: 10.1039/C9AY01942A, PaperSimon Forest, Trevor Théorêt, Julien Coutu, Jean-Francois MassonA simple colorimetric test detects off-flavour profiles of maple syrups in minutes, which are detectable by the naked eye.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
aggregation [ASAP] Structural Characterization of Individual a-Synuclein Oligomers Formed at Different Stages of Protein Aggregation by Atomic Force Microscopy-Infrared Spectroscopy By feedproxy.google.com Published On :: Fri, 01 May 2020 04:00:00 GMT Analytical ChemistryDOI: 10.1021/acs.analchem.0c00593 Full Article
aggregation [ASAP] Highly Sensitive and Selective Detection of Heparin in Serum Based on a Long-Wavelength Tetraphenylethylene–Cyanopyridine Aggregation-Induced Emission Luminogen By feedproxy.google.com Published On :: Tue, 05 May 2020 04:00:00 GMT Analytical ChemistryDOI: 10.1021/acs.analchem.0c00496 Full Article
aggregation Different-shaped micro-objects driven by active particle aggregations By feeds.rsc.org Published On :: Soft Matter, 2020, Advance ArticleDOI: 10.1039/D0SM00160K, PaperChen Wang, Hongyuan JiangWe study the dynamics of passive micro-objects in the active bath. The motion of micro-objects depends on the pattern of active particle aggregations.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
aggregation Development of novel N-(6-methanesulfonyl-benzothiazol-2-yl)-3-(4-substituted-piperazin-1-yl)-propionamides with cholinesterase inhibition, anti-β-amyloid aggregation, neuroprotection and cognition enhancing properties for the therapy of Alzheimer's d By feeds.rsc.org Published On :: RSC Adv., 2020, 10,17602-17619DOI: 10.1039/D0RA00663G, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Chandra Bhushan Mishra, Shruti Shalini, Siddharth Gusain, Amresh Prakash, Jyoti Kumari, Shikha Kumari, Anita Kumari Yadav, Andrew M. Lynn, Manisha TiwariA novel series of benzothiazole–piperazine hybrids were rationally designed, synthesized, and evaluated as multifunctional ligands against Alzheimer's disease (AD).The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
aggregation JAMA Pediatrics : Sibling Recurrence Risk and Cross-aggregation of ADHD and Autism Spectrum Disorder By traffic.libsyn.com Published On :: Mon, 10 Dec 2018 16:00:00 +0000 Interview with Meghan Miller, PhD, author of Sibling Recurrence Risk and Cross-aggregation of Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder Full Article
aggregation Heat-resistant Pb(II)-based X-ray scintillating metal-organic frameworks for sensitive dosage detection via the aggregation-induced luminescent chromophore By feeds.rsc.org Published On :: Dalton Trans., 2020, Accepted ManuscriptDOI: 10.1039/D0DT00974A, CommunicationJian Lu, Shuai-Hua Wang, Yan Li, Wen-Fei Wang, Cai Sun, Pei-Xin Li, Fa-Kun Zheng, Guo-Cong GuoThe synergy of unusual X-aggregation induced luminescent chromophores and heavy Pb(II) ions has facilitated excellent X-ray scintillation of two structurally similar Pb-SMOFs, which are heat-resistant due to solvent-free lattices. Owing...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
aggregation [ASAP] Protective Effects of a Neurohypophyseal Hormone Analogue on Prion Aggregation, Cellular Internalization, and Toxicity By feedproxy.google.com Published On :: Tue, 20 Aug 2019 04:00:00 GMT ACS Chemical NeuroscienceDOI: 10.1021/acschemneuro.9b00299 Full Article
aggregation [ASAP] A Master Regulator of a-Synuclein Aggregation By feedproxy.google.com Published On :: Fri, 01 May 2020 04:00:00 GMT ACS Chemical NeuroscienceDOI: 10.1021/acschemneuro.0c00216 Full Article
aggregation Enhanced type I photoreaction of indocyanine green via electrostatic-force-driven aggregation By feeds.rsc.org Published On :: Nanoscale, 2020, 12,9517-9523DOI: 10.1039/D0NR01208D, PaperHuizhen Fan, Yu Fan, Wenna Du, Rui Cai, Xinshuang Gao, Xinfeng Liu, Hao Wang, Lei Wang, Xiaochun WuICG forms aggregates in positively charged mesoporous silica, which show an enhanced type I photoreaction pathway.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
aggregation Size-dependent aggregation of hydrophobic nanoparticles in lipid membranes By feeds.rsc.org Published On :: Nanoscale, 2020, 12,9452-9461DOI: 10.1039/D0NR00868K, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Enrico Lavagna, Jonathan Barnoud, Giulia Rossi, Luca MonticelliAggregation of hydrophobic spherical nanoparticles in lipid membranes depends on nanoparticle size. Nanoparticles of ∼3 nm sense and induce membrane curvature.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
aggregation A mathematical model for colloidal aggregation By digital.lib.usf.edu Published On :: Sat, 15 Feb 2014 18:08:53 -0400 Full Article
aggregation Continuous time disaggregation in hierarchical production planning By digital.lib.usf.edu Published On :: Sat, 15 Feb 2014 18:36:30 -0400 Full Article
aggregation Aggregational behavior and nest ownership of Crawfodapis luctuosa (Diphaglossinae : Apidae) By digital.lib.usf.edu Published On :: Fri, 21 Mar 2014 13:58:53 -0400 Full Article
aggregation The Identification of Prehistoric Hunter-Gatherer Aggregation Sites: The Case of Altamira [and Comments and Reply] By digital.lib.usf.edu Published On :: Tue, 07 Apr 2020 09:07:23 -0400 Full Article
aggregation Diapause aggregations in Stenotarsus sp. (Endomychidae) By digital.lib.usf.edu Published On :: Fri, 17 Apr 2020 12:49:06 -0400 Full Article
