1

Now, a mobile app predicts COVID-19 incidence days in advance

The predictive power of the App highlights the potential utility of real-time symptom tracking




1

‘COVID-19 death is a wake-up call to improve surveillance in the area’

Even after more than six weeks of national lockdown, there is no sign of any flattening of the curve but instead the number of new novel coronavirus c




1

PE/VC investments hit 24-month low of $1.7 bn, value falls by 39%

Uncertainty over the impact of Covid-19 is expected to act as a significant headwind to Indian PE/VC investments




1

PE-VC companies invest $5.9 billion across 164 deals in the Q4FY20

The latest quarter witnessed 14 PE-VC investments worth $100 million or more, down from the 20 such transactions in the same period last year




1

PE and VC investments at $5.1 billion in 1Q2020; a 12-quarter low: IVCA-EY

At $2.2 billion, large deals declined by over 70 per cent on a year-on-year basis in the same period




1

[ASAP] PTP1B-Inhibiting Branched-Chain Fatty Acid Dimers from <italic toggle="yes">Eremophila oppositifolia</italic> subsp. <italic toggle="yes">angustifolia</italic> Identified by High-Resolution PTP1B Inhibiti

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00070




1

[ASAP] 6-Deoxy- and 11-Hydroxytolypodiols: Meroterpenoids from the Cyanobacterium HT-58-2

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b00844




1

[ASAP] Synthesis of the 1,2,4-Thiadiazole Alkaloid Polyaurine B

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00166




1

[ASAP] Correction to Corrected Structure of Natural Hyacinthacine C<sub>1</sub> via Total Synthesis

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00389




1

[ASAP] Antitubercular Ilamycins from Marine-Derived <italic toggle="yes">Streptomyces atratus</italic> SCSIO ZH16 ?<italic toggle="yes">ilaR</italic>

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00151




1

[ASAP] Review of Progress in the Chemistry of Organic Natural Products<source>Progress in the Chemistry of Organic Natural Products</source>, Volume 108. Edited by A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Jun’ichi Kobayashi, Yoshinori A

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00356




1

[ASAP] Effect of Temperature on <sup>1</sup>H NMR Spectra, Antitrypanosomal Activity, Conformational Analysis, and Molecular Docking of Curine Derivatives from <italic toggle="yes">Berberis brevissima</italic>

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b00397




1

[ASAP] Structural Specificity of Flavonoids in the Inhibition of Human Fructose 1,6-Bisphosphatase

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00014




1

[ASAP] Advances in the Biosynthesis of Pyranocoumarins: Isolation and <sup>13</sup>C-Incorporation Analysis by High-Performance Liquid Chromatography–Ultraviolet–Solid-Phase Extraction–Nuclear Magnetic Resonance Data

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b00607




1

Highlight.js 10, Node 14, and modern React in 20 minutes

#485 — April 24, 2020

Unsubscribe  :  Read on the Web

JavaScript Weekly

Introducing Crank.js: A New JSX-Driven Framework — A new framework for creating JSX-driven components with functions, promises and generators. If you haven’t got time to read the creator’s lengthy (but well worth reading!) rationale for creating another framework, check out the GitHub repo or jump straight into a CodeSandbox example. I hope to see a lot more about this in the near future.

Brian Kim

The Cost of JavaScript Frameworks — Using data from the HTTP Archive, Tim explores the performance cost of using various popular frameworks as a starting point. Some good analysis here.

Tim Kadlec

You Hacked the Gibson? Yeah, They Built Their Own Login — Don't let Crash Override pwn your app. FusionAuth adds secure login, registration and user management to your app in minutes not months. Download our community edition for free.

FusionAuth sponsor

Node.js 14 Released — v14 now becomes the current ‘release’ line with it becoming a LTS (Long Term Support) release in October. Diagnostic reports are now a stable feature, it now uses V8 8.1, there's an experimental Async Local Storage API, and more.

Michael Dawson and Bethany Griggs

Vidact: A Compiler to Convert React-like Apps to Vanilla JS — Compiles pure React-compatible JavaScript (JSX) to vanilla JavaScript with no virtual DOM.. think similar to Svelte, but without introducing a new syntax. A curious idea.

Mohamad Mohebifar

Highlight.js 10.0: The Web Syntax Highlighter Library — I always laugh when I see a big release of a popular library and saw we last linked it 5 years ago ???? Nonetheless, this is a big release and Highlight.js continues to be a fantastic library for syntax highlighting code.

highlight.js

???? Jobs

Senior Full-stack Developer (Malmö/Sweden) — Every day is different from the next. Join our upbeat Team and work on exciting, major projects using a modern JavaScript stack.

Ortelius AB

Find a Job Through Vettery — Vettery specializes in tech roles and is completely free for job seekers. Create a profile to get started.

Vettery

???? Tutorials

▶  React: The Basics in 20 Minutes — A well presented, up to date (yep, it covers hooks) tutorial that doesn’t hang around, whether you’re new to React or just want a refresher.

Devistry

Creating Web Apps via TypeScript and webpack — The example app doesn’t use any front-end framework, just vanilla DOM APIs. Some knowledge of TypeScript, webpack, and npm are required, but this is a neat way to bring together a bunch of tools.

Axel Rauschmayer

What Is The toJSON() Function? — If an object has a toJSON function, JSON.stringify() calls toJSON() and serializes the return value from toJSON() instead.

Valeri Karpov

A Much Faster Way to Debug Code Than with Breakpoints or console.log — Move forward and backwards through your code to understand what led to a specific bug, view runtime values, edit-and-continue, and more.

Wallaby.js sponsor

How Does TypeScript Work? A Bird’s Eye View — Dr. Axel goes into depth on the structure of a typical TypeScript project, what gets compiled, and how can an IDE be used to write TypeScript. Aimed at people who haven’t yet picked TypeScript up.

Axel Rauschmayer

10 Lesser Known Angular Features You've Probably Never Used

W3Radar

You Might Not Need switch — Using an object of outcomes instead of switch suits many use cases, though take care over readability.

Valentino Gagliardi

???? Upcoming Online Events

  • Pick JS (May 8) — Aimed at intermediate to expert JS developers rather than beginners.
  • JavaScript Remote Conf 2020 (May 14-15) — Speakers lined up already include Douglas Crockford, Aimee Knight and Christian Heilmann.
  • ESNEXT CONF 2020 (May 18-22) — From the Pika folks (of Snowpack fame). 12 speakers over 5 days so it's a gradual pace.
  • ForwardJS (May 26-29) — A real world event (ForwardJS Ottawa) that has now become a virtual event.
  • CascadiaJS 2020 (September 1-2) — This upcoming online conference is set to take place in September, and the CFP is open now through May 15.

???? Code & Tools

Phelia: A Reactive Slack Application Framework — If you think Slack apps were all about text bots, think again.. you can now create apps complete with in-app UIs. Phelia brings the React approach to the task.

Max Chehab

Marked.js 1.0: A Fast Markdown Parser and Compiler — Got Markdown to render? Marked.js to the rescue. While the project is years old, 1.0 has dropped just this week. Here’s a live demo.

Christopher Jeffrey

Stream Chat API & JavaScript SDK for Custom Chat Apps — Build real-time chat in less time. Rapidly ship in-app messaging with our highly reliable chat infrastructure.

Stream sponsor

Alpine.js: A Minimal Framework for Composing JS Behavior in Your Markup — We only gave Alpine a brief link when it first dropped but with new versions coming out thick and fast, we think it’s well worth a look. Billed as “like Tailwind for JavaScript”, Alpine lets you keep the HTML you know and love and just pepper it with JavaScript as and where appropriate.

Alpine.js

enroute: A React Router with a Small Footprint for Modern Browsers

TJ Holowaychuk

Rosetta: A General Purpose Internationalization Library in 292 Bytes — Less than 300 bytes, but does have a few dependencies. Aims to be very simple and is targeted at basic string use cases.

Luke Edwards

NAB 2020 May Be Canceled, But The Full Bitmovin Experience Is Not

Bitmovin Inc. sponsor

Hotkey 1.4: Trigger an Action on an Element When a 'Hotkey' is Pressed — Use Hotkey, set the data-hotkey attribute on your elements, and you get keyboard shortcuts. GitHub built and uses it (look for the data-hotkey attributes on their pages).

GitHub

web-worker: Consistent Web Workers for the Browser and Node — In Node it works as a web-compatible Worker implementation atop worker_threads. In the browser it’s an alias for Worker.

Jason Miller




1

Govt not included AGR dues payment in Budget 2020-21: DEA Secretary

15 entities owe the government about Rs 1.47 trillion in past dues -- Rs 92,642 crore in unpaid licence fee and another Rs 55,054 crore in outstanding spectrum usage charges




1

LIC disinvestment: 100,000 employees stage walk-out across country

There are 13 unions in LIC, and employees and officers affiliated to 11 unions were on protest




1

Budget proposes to shut thermal power plants of 166,000 mw, says group

National powermen body to stage protests against 'anti-people' proposals




1

ITC is first to hike cigarette prices post budget; makes them 10-20% dearer

Price increase brought on by spike in National Calamity Contingency Duty announced in Budget




1

Yogi govt to table Budget 2020-21 on February 18; session starts Thursday

The size of the UP Annual Budget 2020-21 is expected to breach the historic mark of Rs 5 trillion




1

Odisha tables revenue surplus budget with total outgo pegged at Rs 1.5 trn

Budget estimates fiscal deficit to be at 3.4%, within permissible limit of FRBM target




1

Physician Communication in the 21st Century

Interview with Allan S. Detsky, MD, PhD, author of Physician Communication in the 21st Century




1

Application of Electronic Health Records to the Joint Commission's 2011 National Patient Safety Goals

Interview with Ryan Radecki, MD, author of Application of Electronic Health Records to the Joint Commission's 2011 National Patient Safety Goals




1

Graduated Driver Licensing and Fatal Crashes Involving 16- to 19-Year-Old Drivers

Interview with Scott V. Masten, PhD, author of Graduated Driver Licensing and Fatal Crashes Involving 16- to 19-Year-Old Drivers




1

National and Regional Trends in Heart Failure Hospitalization and Mortality Rates for Medicare Beneficiaries, 1998-2008

Interview with Jersey Chen, MD, MPH, author of National and Regional Trends in Heart Failure Hospitalization and Mortality Rates for Medicare Beneficiaries, 1998-2008




1

JAMA: 2012-04-11, Vol. 307, No. 14, Author Interview

Interview with Donald M. Berwick, MD, MPP, author of Eliminating Waste in US Health Care




1

Use of Diagnostic Imaging Studies and Associated Radiation Exposure for Patients Enrolled in Large Integrated Health Care Systems, 1996-2010

Interview with Rebecca Smith-Bindman, MD, author of Use of Diagnostic Imaging Studies and Associated Radiation Exposure for Patients Enrolled in Large Integrated Health Care Systems, 1996-2010




1

Epidemiology of Staphylococcus aureus Blood and Skin and Soft Tissue Infections in the US Military Health System, 2005-2010

Interview with Clinton K. Murray, MD, author of Epidemiology of Staphylococcus aureus Blood and Skin and Soft Tissue Infections in the US Military Health System, 2005-2010




1

Risk of Adverse Fetal Outcomes Following Administration of a Pandemic Influenza A(H1N1) Vaccine During Pregnancy

Interview with Björn Pasternak, MD, PhD, author of Risk of Adverse Fetal Outcomes Following Administration of a Pandemic Influenza A(H1N1) Vaccine During Pregnancy




1

HIV in Persons Born Outside the United States, 2007-2010

Interview with Adria Tassy Prosser, PhD, author of HIV in Persons Born Outside the United States, 2007-2010




1

Trends in Serum Lipids Among US Youths Aged 6 to 19 Years, 1988-2010

Interview with Brian K. Kit, MD, MPH, author of Trends in Serum Lipids Among US Youths Aged 6 to 19 Years, 1988-2010




1

Total Knee Arthroplasty Volume, Utilization, and Outcomes Among Medicare Beneficiaries, 1991-2010

Interview with Peter Cram, MD, MBA, author of Total Knee Arthroplasty Volume, Utilization, and Outcomes Among Medicare Beneficiaries, 1991-2010




1

Trends in Lipids and Lipoproteins in US Adults, 1988-2010

Interview with Margaret D. Carroll, MSPH, author of Trends in Lipids and Lipoproteins in US Adults, 1988-2010




1

Hospitalizations and Mortality Associated With Norovirus Outbreaks in Nursing Homes, 2009-2010

Interview with Tarak K. Trivedi, BS, author of Hospitalizations and Mortality Associated With Norovirus Outbreaks in Nursing Homes, 2009-2010




1

Association of Childhood Pertussis With Receipt of 5 Doses of Pertussis Vaccine by Time Since Last Vaccine Dose, California, 2010

Interview with Lara K. Misegades, PhD, MS, author of Association of Childhood Pertussis With Receipt of 5 Doses of Pertussis Vaccine by Time Since Last Vaccine Dose, California, 2010




1

Prevalence of Nonrefractive Visual Impairment in US Adults and Associated Risk Factors, 1999-2002 and 2005-2008

Interview with David S. Friedman, MD, MPH, PhD, author of Prevalence of Nonrefractive Visual Impairment in US Adults and Associated Risk Factors, 1999-2002 and 2005-2008




1

Prevalence of and Risk Factors for Autopsy-Determined Atherosclerosis Among US Service Members, 2001-2011

Interview with Bryant J. Webber, MD, author of Prevalence of and Risk Factors for Autopsy-Determined Atherosclerosis Among US Service Members, 2001-2011




1

Long-term Mortality After Stroke Among Adults Aged 18 to 50 Years

Interview with Frank-Erik de Leeuw, MD, PhD and Loes C. A. Rutten-Jacobs, MSc, authors of Long-term Mortality After Stroke Among Adults Aged 18 to 50 Years




1

The State of US Health, 1990-2010: Burden of Diseases, Injuries, and Risk Factors

Interview with Christopher J. L. Murray, MD, DPhil, author of The State of US Health, 1990-2010: Burden of Diseases, Injuries, and Risk Factors




1

The 2012 West Nile Encephalitis Epidemic in Dallas, Texas

Interview with Wendy M. Chung, MD, SM, author of The 2012 West Nile Encephalitis Epidemic in Dallas, Texas




1

Sofosbuvir and Ribavirin for Hepatitis C Genotype 1 in Patients With Unfavorable Treatment Characteristics: A Randomized Clinical Trial

Interview with Anthony S. Fauci, MD, author of Sofosbuvir and Ribavirin for Hepatitis C Genotype 1 in Patients With Unfavorable Treatment Characteristics: A Randomized Clinical Trial




1

2014 Evidence-Based Guideline for the Management of High Blood Pressure in Adults: Report From the Panel Members Appointed to the Eighth Joint National Committee (JNC 8)

Interview with Paul A. James, MD, author of 2014 Evidence-Based Guideline for the Management of High Blood Pressure in Adults: Report From the Panel Members Appointed to the Eighth Joint National Committee (JNC 8)




1

Tobacco Control and the Reduction in Smoking-Related Premature Deaths in the United States, 1964-2012

Interview with Theodore R. Holford, PhD, author of Tobacco Control and the Reduction in Smoking-Related Premature Deaths in the United States, 1964-2012




1

Clinical Trial Evidence Supporting FDA Approval of Novel Therapeutic Agents, 2005-2012

Interview with Joseph S. Ross, MD, MHS, author of Clinical Trial Evidence Supporting FDA Approval of Novel Therapeutic Agents, 2005-2012




1

Proportion of US Adults Potentially Affected by the 2014 Hypertension Guideline

Interview with Ann Marie Navar-Boggan, MD, PhD, author of Proportion of US Adults Potentially Affected by the 2014 Hypertension Guideline




1

Prevalence of Type 1 and Type 2 Diabetes Among Children and Adolescents From 2001 to 2009

Interview with Dana Dabelea, MD, PhD, author of Prevalence of Type 1 and Type 2 Diabetes Among Children and Adolescents From 2001 to 2009




1

Use of and Mortality After Bilateral Mastectomy Compared With Other Surgical Treatments for Breast Cancer in California, 1998-2011

Interview with Allison W. Kurian, MD, MSc, author of Use of and Mortality After Bilateral Mastectomy Compared With Other Surgical Treatments for Breast Cancer in California, 1998-2011




1

Prevalence of Antimicrobial Use in US Acute Care Hospitals, May-September 2011

Interview with Shelley S. Magill, MD, PhD, author of Prevalence of Antimicrobial Use in US Acute Care Hospitals, May-September 2011




1

Cost-effectiveness of Varying 10-Year Risk Statin Treatment Thresholds

Interview with Thomas A. Gaziano, MD, MSc, author of Cost-effectiveness of 10-Year Risk Thresholds for Initiation of Statin Therapy for Primary Prevention of Cardiovascular Disease