1

Continuous flow synthesis of the URAT1 inhibitor lesinurad

React. Chem. Eng., 2020, 5,865-872
DOI: 10.1039/C9RE00483A, Paper
Mariana C. F. C. B. Damião, Henrique M. Marçon, Julio Cezar Pastre
A 5-steps continuous flow synthesis of lesinurad is provided and delivers this API in 68% overall yield.
The content of this RSS Feed (c) The Royal Society of Chemistry




1

Synthesis of 3-trifluoromethylated 1,3-butadienes via a Pd(0)-catalyzed fluorinated Heck reaction

React. Chem. Eng., 2020, 5,961-966
DOI: 10.1039/D0RE00093K, Paper
Yang Li, Meng Hao, Ming Xia, Ning Sun, Cai-Lin Zhang, Wen-Qing Zhu
1,3-Butadienes play a key role in modern synthetic chemistry and biochemistry because they are well-known precursors for the synthesis of retinoids.
The content of this RSS Feed (c) The Royal Society of Chemistry




1

Sustainable chemo-enzymatic preparation of enantiopure (R)-β-hydroxy-1,2,3-triazoles via lactic acid bacteria-mediated bioreduction of aromatic ketones and a heterogeneous “click” cycloaddition reaction in deep eutectic solvents

React. Chem. Eng., 2020, 5,859-864
DOI: 10.1039/D0RE00067A, Communication
Paola Vitale, Francesco Lavolpe, Francesca Valerio, Mariaelena Di Biase, Filippo Maria Perna, Eugenia Messina, Gennaro Agrimi, Isabella Pisano, Vito Capriati
A chemo-enzymatic strategy for the preparation of enantiopure (R)-β-hydroxy-1,2,3-triazoles using a lactic acid bacterium as a whole-cell biocatalyst and a heterogeneous “click” cycloaddition reaction in deep eutectic solvents is disclosed.
The content of this RSS Feed (c) The Royal Society of Chemistry




1

Outstanding Reviewers for Reaction Chemistry & Engineering in 2019

React. Chem. Eng., 2020, 5,813-813
DOI: 10.1039/D0RE90016H, Editorial

We would like to take this opportunity to highlight the Outstanding Reviewers for Reaction Chemistry & Engineering in 2019, as selected by the editorial team for their significant contribution to the journal.
The content of this RSS Feed (c) The Royal Society of Chemistry




1

[ASAP] Dynamics and Interactions of GPI-Linked lynx1 Protein with/without Nicotinic Acetylcholine Receptor in Membrane Bilayers

The Journal of Physical Chemistry B
DOI: 10.1021/acs.jpcb.0c00159




1

[ASAP] Characterization of Long Linear and Branched Alkanes and Alcohols for Temperatures up to 573.15 K by Surface Light Scattering and Molecular Dynamics Simulations

The Journal of Physical Chemistry B
DOI: 10.1021/acs.jpcb.0c01740




1

Coronavirus | It’s like 2nd innings of Test match, says Kumble on fight against COVID-19

Anil Kumble thanked all the health care workers and others who are going on with their work so that everyone else can stay safe at home.




1

This Bengaluru NGO sells handmade COVID-19 masks by women artisans

Sixty underprivileged women artisans from Bengaluru and Hyderabad make the masks sold by Craftizen Foundation



  • Life & Style

1

The changing landscape of fashion photography in a COVID-19 world

An alternative photography technique using mobile technology is fast emerging as a trend among shutterbugs who have had to adapt to the changing landscape of photoshoots due to COVID-19




1

ICICI Bank Q4 net rises 26% to ₹1,221 crore

On the assets front, gross non-performing assets (NPAs) stood at 5.53% of gross advances as on March 31, 2020, compared to 6.70 per cent last year.




1

COVID-19 deaths in Italy exceed 30,000

The country now has 217,185 confirmed coronavirus infections.




1

Coronavirus India lockdown Day 46 live updates | Testing capacity for COVID-19 scaled up to 95,000 per day: Harsh Vardhan

India's recovery rate currently stands at 29.36%, according to the Union Health Ministry.




1

China continues to hide, obfuscate COVID-19 data from world: Pompeo

By Friday, more than 78,000 Americans had died and 13 lakh tested positive for the coronavirus. Globally, more than 274,000 people have died and 39 lakh have tested positive for the disease, according to Johns Hopkins University data.




1

Manipur gears up for arrival of residents from May 12

Chief Minister N. Biren directs district administrations to make arrangements for quarantining them.




1

Odisha govt extends work shift to 12 hours

It modifies the existing eight-hour shift after representations from industries




1

365 Kashmiri students to return home from Bhopal in 18 buses

The students are currently accommodated in a private school in Bhopal.




1

Only those with severe COVID-19 illness need to be tested before discharge: Health Ministry

As per latest guideline, other categories of patients need not be tested before discharge




1

SBI complains to CBI after ₹411 crore loan defaulters flee country

The CBI had recently booked Ram Dev International and its directors Naresh Kumar, Suresh Kumar and Sangita




1

COVID-19 | Five Bihar Military Police personnel test positive

Tally in State goes up to 580




1

Special cargo flight lifts 11 tonnes of vegetables, flowers from Tiruchi to Singapore

The flight, operated by SpiceJet, is the first exclusive freighter service from Tiruchi since the COVID-19 lockdown began




1

COVID-19 | Karnataka reports 36 new cases

State tally goes up to 789




1

Coronavirus lockdown | 150 enter State via Muthanga

Those without domestic pass would be sent back, say authorities




1

Private lab in Kolkata sealed for illegal COVID-19 tests

Government urges people to go only to approved centres.




1

9,194 migrants return

As many as 9,194 migrants working in different districts and States have returned to the district after the government granted permission for the tran




1

One more person tests COVID-19 positive in Puducherry

This takes the total number of active cases in the Union Territory to three




1

COVID-19: Public art in Hyderabad to spread awareness

Md. Abdul Basith, with a team of 15 artists, spreads awareness on the lockdown through public art at various junctions in the city




1

COVID-19 | Three more deaths, 43 fresh cases reported in AP

The State reported three more COVID-19 deaths and 43 fresh cases during the past 24 hours during which 8,388 samples were tested. The tally has reache




1

AJL case: ED attaches assets worth over ₹16 crore

Agency probing alleged irregular re-allotment of Panchkula plot to firm in 2005




1

Providing adequate ration to Rohingya refugees during COVID-19 lockdown: AAP govt to HC

The Bench was hearing a plea seeking immediate relief for the Rohingya families at settlements in Khajuri Khas in north east Delhi and Shram Vihar and Madanpur Khadar in south Delhi




1

Adityanath reviews COVID-19 situation in Uttar Pradesh

The Chief Minister said an elaborate work plan should be formulated to make employment available to migrant labourers, and women self-help groups should be trained on a large scale




1

Coronavirus | ‘Confusion’ within central government in fight against COVID-19, says Congress

Maken also came down heavily on the Arvind Kejriwal-led government and asked it to be more transparent in reporting cases of the novel coronavirus.




1

Tamil Nadu to further relax COVID-19 lockdown restrictions from Monday

Timings for shops and fuel outlets have been extended, and tea shops will be able to offer parcel services




1

U.K. plans 14-day compulsory quarantine for all airport arrivals

The new restriction, which means travellers including Britons arriving in the UK would have to self-isolate at a private residence or be fined up to £1,000 or be deported for flouting the rules, is expected to take effect at the end of this month




1

Coronavirus lockdown | Evaluation for class 10, 12 board exams to be done at home by teachers

The pending board exams will be held from July 1 to 15.




1

Coronavirus | Testing capacity for COVID-19 scaled up to 95,000 per day, says Harsh Vardhan

Harsh Vardhan flagged the large prevalence of non-smoking tobacco usage in some of the States and the problem of spitting in public places.




1

1,138 patients, caregivers leave for Patna

4,000 people from West Bengal waiting to return home




1

09/16:01 WST Marine Wind Warning Summary for Western Australia




1

1st train with Rajasthan migrants reach Jodhpur




1

Covid-19: Toll now 100 in R'sthan; tally 3,453




1

Panic at rly hosp as 13-yr-old girl tests +ve

Panic prevailed at the railway hospital in Ganpati Nagar when a 13-year-old daughter of a railway employee was found positive.




1

76 new Covid-19 cases in Rajasthan, tally 3,655

With 76 new Covid-19 cases reported on Saturday in Rajasthan, the state tally of people infected from the virus has surged to 3,655 out of which 1,526 are active cases.




1

Covid-19 to push UK economy towards deepest recession: Bank of England

It would also be the sharpest annual contraction since 1706, according to reconstructed Bank of England data going back to the 18th Century




1

Suspend guest worker visas, including H-1B for 60 days: Senators to Trump

The unemployment figures in the US have reached an all-time high due to the coronavirus pandemic




1

IMF approves $18 bn emergency financing for 50 countries during Covid-19

In order to ensure full transparency and prevent any misuse of funds, the IMF asked member countries who apply for financing to commit that it is only used for urgent purposes related to Covid-19.




1

Rupert Murdoch gives up yearly bonus after News Corp reports $1 bn loss

News Corp also reported an 8% drop in revenue to $2.27 billion, hurt by a weaker Australian dollar and lower subscription at Foxtel.




1

Canada loses record 2 mn jobs in April, unemployment rate surges to 13%

As of May 5, more than 7.5 million Canadians had applied for some form of federal employment aid, according to government data.




1

Covid-19: US jobless rate spikes to 14.7%, highest since Great Depression

The figures are stark evidence of the damage the coronavirus has done to a now-shattered economy




1

Indian envoy Sandhu, US Senator Feinstein discuss ways to tackle Covid-19

The United States is the worst affected country in the world from coronavirus with over 1.25 million cases in the country




1

Hong Kong eases lockdown as no local Covid-19 transmission seen in 19 days

While gyms, beauty salons, bars, restaurants and other such public places have been reopened, saunas, karaoke lounges, party rooms and nightclubs would remain closed for at least another two weeks




1

Covid-19: India tally close to 60K mark; Russia reports 10,000 new cases

Russia, which has emerged as a new Covid-19 hotspot in Europe, on Friday registered more than 10,000 new Covid-19 cases, for a sixth straight day