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CBD Communiqué: First Regional Response to the Nagoya Outcomes Will Be Elaborated in the Arab Region.

By www.cbd.int
Published On :: Mon, 08 Nov 2010 00:00:00 GMT


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CBD News: Statement by Mr. Ahmed Djoghlaf, CBD Executive Secretary, on the occasion of the Arab Regional Workshop on Biodiversity and Finance, 29 November 2010, Cairo.

By www.cbd.int
Published On :: Mon, 29 Nov 2010 00:00:00 GMT


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CBD News: Statement by Mr Ahmed Djoghlaf, CBD Executive Secretary, on the occasion of the Second International Colloquium on "Biodiversity - Theoretical and Practical Aspects", 3 December 2010, Sarajevo, Bosnia and Herzegovina.

By www.cbd.int
Published On :: Fri, 03 Dec 2010 00:00:00 GMT


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CBD News: Statement by Mr Ahmed Djoghlaf, CBD Executive Secretary, on the occasion of International Workshop on Biodiversity and Climate Change, 19-22 December 2010, Kharagpur, India.

By www.cbd.int
Published On :: Sun, 19 Dec 2010 00:00:00 GMT


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CBD News: Statement by Mr Ahmed Djoghlaf, CBD Executive Secretary, on the occasion of Regional Workshop Training to Support The Preparation of the State of the World's Forest Genetic Resources in the Pacific, 19-21 January 2011, Nadi, Fiji Islands.

By www.cbd.int
Published On :: Wed, 19 Jan 2011 00:00:00 GMT


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CBD News: Statement by Mr Ahmed Djoghlaf, CBD Executive Secretary, on the Occasion of the Regional Workshop to Support the Preparation of the State of the World's Forest Genetic Resources in Africa, 27-29 April 2011, Nairobi.

By www.cbd.int
Published On :: Wed, 27 Apr 2011 00:00:00 GMT


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CBD Press Release: India Launches National Preparations for the 2012 Hyderabad Biodiversity Summit

By www.cbd.int
Published On :: Mon, 23 May 2011 00:00:00 GMT


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CBD News: Déclaration de mr. Ahmed Djoghlaf, Secrétaire exécutif de la Convention sur la diversite biologique, à l'occasion de la 9ème comité consultatif régional (CCR) - partenariat pour les forêts du bassin

By www.cbd.int
Published On :: Wed, 25 May 2011 00:00:00 GMT


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CBD Communiqué: Arabic version of CBD website inaugurated as a contribution to achieving the objectives of the United Nations Decade on Biodiversity

By www.cbd.int
Published On :: Mon, 06 Jun 2011 00:00:00 GMT


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CBD News: The new Indian Minister of Environment and Forests, HE Jayanthi Natarajan, invites all Parties to the high-level segment of COP-11 at Hyderabad International Convention Centre from 17 to 19 October 2012 highlighting five key issues for discussio

By www.cbd.int
Published On :: Tue, 09 Aug 2011 00:00:00 GMT


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CBD Communiqué: The Preparation of the Global City and Biodiversity Outlook launched

By www.cbd.int
Published On :: Fri, 16 Sep 2011 00:00:00 GMT


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CBD Communiqué: Biodiversity on top of the environmental agenda in the Arab region

By www.cbd.int
Published On :: Tue, 10 Jan 2012 00:00:00 GMT


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CBD Press Release: Jordan becomes first country in the Arab region to ratify the Nagoya Protocol on genetic resources

By www.cbd.int
Published On :: Thu, 12 Jan 2012 00:00:00 GMT


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CBD Press Release: Montreal, 6 July 2012. With a spirit of compromise and constructive engagement, Governments concluded a week-long meeting where they advanced in the preparations for the entry into force of the Nagoya Protocol on Access and Benefit-shar

By www.cbd.int
Published On :: Fri, 06 Jul 2012 00:00:00 GMT


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CBD News: Statement by Mr. Braulio F. de Souza Dias, CBD Executive Secretary, to the Subregional Capacity-Building Workshop to Address Invasive Alien Species and to Achieve Aichi Biodiversity Target 9 in the Arab Region, 11 - 14 February 2013, Dubai, Unit

By www.cbd.int
Published On :: Mon, 11 Feb 2013 00:00:00 GMT


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CBD News: Allocution de m. Braulio F. de Souza Dias, Secrétaire exécutif de la CDB, à l'occasion de l'ouverture du deuxième atelier régional pour les pays moins avancés d'Afrique sur la préparation des cinqui

By www.cbd.int
Published On :: Mon, 15 Apr 2013 00:00:00 GMT


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CBD News: Statement by Mr. Braulio F. de Souza Dias , CBD Executive Secretary, at the opening of the Regional Workshop for South, East and Southeast Asia on the Preparation of the Fifth National Report and Regional Scenario Analysis, Incheon City, Republi

By www.cbd.int
Published On :: Mon, 20 May 2013 00:00:00 GMT


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CBD Press Release: Comoros, Mongolia and the Syrian Arab Republic ratify Nagoya Protocol.

By www.cbd.int
Published On :: Thu, 06 Jun 2013 00:00:00 GMT


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CBD News: Statement by Mr. Braulio F. de Souza Dias, CBD Executive Secretary, at the Opening of the Regional Workshop for the Caribbean Countries on the Preparation of the Fifth National Report and the Regional Workshop for the Caribbean Countries on the

By www.cbd.int
Published On :: Mon, 16 Sep 2013 00:00:00 GMT


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CBD News: The Natural Capital Declaration (NCD) has been declared a Biodiversity Champion by the Secretariat of the Convention on Biological Diversity (CBD) in recognition of its important contribution to the implementation of the Convention's Strateg

By www.cbd.int
Published On :: Mon, 11 Nov 2013 00:00:00 GMT


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CBD News: Statement by Mr. Braulio F. de Souza Dias, CBD Executive Secretary, at the Opening of the Regional Workshop for Middle East and North Africa on the Preparation of the Fifth National Report, Doha, Qatar, 14-17 December 2013

By www.cbd.int
Published On :: Sat, 14 Dec 2013 00:00:00 GMT


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CBD News: Governments meet in Pyeongchang, Republic of Korea this week for discussions which will finalise preparations for the first meeting of the governing body of the Nagoya Protocol on Access to Genetic Resources and the Fair and Equitable Sharing of

By www.cbd.int
Published On :: Mon, 24 Feb 2014 00:00:00 GMT


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CBD News: In preparation of a major international biodiversity conference in October 2014, Parties to the Convention on Biological Diversity (CBD) are currently submitting their fifth national reports that will enable a global assessment of progress made

By www.cbd.int
Published On :: Thu, 10 Apr 2014 00:00:00 GMT


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CBD News: Déclaration de M. Braulio ferreira de Souza Dias, Secrétaire exécutif de la CDB, à l'occasion de l'atelier sur les synergies entre redd + et la conservation et restauration des écosystèmes dans les strat

By www.cbd.int
Published On :: Tue, 08 Jul 2014 00:00:00 GMT


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CBD News: The High Level Segment of the 12th meeting of the Conference of the Parties to the Convention on Biological Diversity adopted the Gangwon Declaration on Biodiversity for Sustainable Development

By www.cbd.int
Published On :: Fri, 17 Oct 2014 00:00:00 GMT


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CBD News: A group of scientists and policymakers delivered a declaration to the Minister of the Environment of Peru, Manuel Pulgar Vidal, the president of UNFCCC Cop-20,that calls for integrated research on biodiversity and climate change and increased re

By www.cbd.int
Published On :: Fri, 05 Dec 2014 00:00:00 GMT


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CBD News: This year, International Women's Day highlights the Beijing Declaration and Platform for Action that twenty years' after its adoption remains an essential roadmap for the achievement of gender equality and women's rights.

By www.cbd.int
Published On :: Sun, 08 Mar 2015 00:00:00 GMT


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CBD News: Déclaration de M. Braulio F. de Souza Dias, Secrétaire exécutif de la CDB, lors de l'ouverture de l'atelier de renforcement des capacités des pays francophones partenaires du centre d'echange d'informations (C

By www.cbd.int
Published On :: Mon, 01 Feb 2016 00:00:00 GMT


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CBD News: First, I would like to congratulate the Arab Society for Fungal Conservation for declaring 20 February as Egyptian Fungus Day. This initiative truly demonstrates commitment towards conservation of biodiversity and promoting the objectives of the

By www.cbd.int
Published On :: Sat, 20 Feb 2016 00:00:00 GMT


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CBD News: The Executive Secretary of the Convention on Biological Diversity, Mr. Braulio Ferreira de Souza Dias, applauds the Arctic Partnership announced Thursday by United States President Barack Obama and Canadian Prime Minister Justin Trudeau in Washi

By www.cbd.int
Published On :: Mon, 14 Mar 2016 00:00:00 GMT


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CBD News: The Subsidiary Body on Implementation at its first meeting urged Parties that have not yet done so to submit their financial reports where feasible by 31 August 2016, in time for the preparation of documentation for the thirteenth meeting of the

By chm.cbd.int
Published On :: Wed, 31 Aug 2016 00:00:00 GMT

f


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CBD News: The 1st Asian Conference on Biocultural Diversity, held from 27-29 October in Nanao City, Ishikawa Prefecture, Japan, produced a regional Declaration on Biocultural Diversity and an annex of practical actions that can be taken at different level

By www.cbd.int
Published On :: Sat, 29 Oct 2016 00:00:00 GMT


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CBD News: Immediately prior to the UN Biodiversity Conference, and in parallel with the High-Level Segment, the Secretariat of the Convention on Biological Diversity (CBD) and the Government of Mexico are hosting the 2016 Business and Biodiversity Forum i

By www.cbd.int
Published On :: Fri, 02 Dec 2016 00:00:00 GMT


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CBD News: Statement by the Secretariat of the Convention on Biological Diversity on behalf of the Executive Secretary at the Preparatory Meeting for the United Nations Conference to Support the Implementation of Sustainable Development Goal 14, New York,

By www.cbd.int
Published On :: Wed, 15 Feb 2017 00:00:00 GMT


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CBD News: Statement by the Secretariat of the Convention on Biological Diversity on behalf of the Executive Secretary at the 4th Session of the Preparatory Committee established by General Assembly resolution 69/292, New York, United States of America, 10

By www.cbd.int
Published On :: Mon, 10 Jul 2017 00:00:00 GMT


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CBD News: The ten-year anniversary of the United Nations Declaration on the Rights of Indigenous Peoples presents a fitting opportunity to draw attention to the significant contribution of indigenous peoples to the conservation and sustainable use of the

By www.cbd.int
Published On :: Tue, 08 Aug 2017 00:00:00 GMT


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CBD News: I want to welcome you to the Subregional Workshop for Arabic Speaking Countries on the Clearing-House Mechanism.

By www.cbd.int
Published On :: Mon, 05 Mar 2018 00:00:00 GMT


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CBD Notification SCBD/IMS/JMF/NS/88541 (2020-002): Preparations for the trial phase of an Open-ended Forum for review of implementation to be held during the third meeting of the Subsidiary Body on Implementation, 27 May 2020 - Montreal, Canada

By www.cbd.int
Published On :: Mon, 06 Jan 2020 00:00:00 GMT


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CBD News: Governments advance in the preparation of a New UN Biodiversity Framework; Negotiations in Rome demonstrate engagement across government and society

By www.cbd.int
Published On :: Sun, 01 Mar 2020 00:00:00 GMT


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Stability, analyticity, and maximal regularity for parabolic finite element problems on smooth domains

By www.ams.org
Published On :: Tue, 07 Apr 2020 14:09 EDT

Takahito Kashiwabara and Tomoya Kemmochi
Math. Comp. 89 (2020), 1647-1679.
Abstract, references and article information


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Music marathon set

By www.news.gov.hk
Published On :: Thu, 02 Jan 2020 00:00:00 +0800

More than 30 local music and dance groups will perform in the Youth Music & Dance Marathon on January 5.

 

The free event presented by the Leisure & Cultural Services Department will be held from 1pm to 6pm that day at the Cultural Centre Piazza.

 

Event highlights will include performances by singers and groups from the Renaissance Foundation and My Main Stage as well as other local bands such as Chonotenki and Gainorva.

 

The Hong Kong Academy for Performing Arts’ School of Dance, the Hong Kong Schools Dance Association and other groups will also give a variety of dance performances such as Chinese, street, jazz, modern, cha-cha-cha, jive and J-pop.

 

Click here for details.


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Jazz marathon set for April

By www.news.gov.hk
Published On :: Wed, 22 Jan 2020 00:00:00 +0800

The city's annual Jazz Marathon will be held on April 25.

 

The all-day music event will see artists from France, India, Italy, Japan, the Mainland, Russia and the US collaborate with local musicians to create a borderless jazz soundscape.

 

The Day Marathon Concert will be held from 2.30pm to 6pm while the Night Marathon Concert will be held from 7.15pm to 10.45pm.

 
Ahead of the concerts, jazz workshops with the artists will be held on April 24.

 

Presented by the Leisure & Cultural Services Department, the events will be held at Queen Elizabeth Stadium in Wan Chai.

 

Tickets are available at URBTIX.

 

Click here for details.


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Secondary Hyperparathyroidism and Chronic Kidney Disease

By spectrum.diabetesjournals.org
Published On :: 2008-01-01

Sarah Tomasello
Jan 1, 2008; 21:19-25
Articles


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12-LOX catalyzes the oxidation of 2-arachidonoyl-lysolipids in platelets generating eicosanoid-lysolipids that are attenuated by iPLA2{gamma} knockout [Signal Transduction]

By www.jbc.org
Published On :: 2020-04-17T00:06:05-07:00

The canonical pathway of eicosanoid production in most mammalian cells is initiated by phospholipase A2-mediated release of arachidonic acid, followed by its enzymatic oxidation resulting in a vast array of eicosanoid products. However, recent work has demonstrated that the major phospholipase in mitochondria, iPLA2γ (patatin-like phospholipase domain containing 8 (PNPLA8)), possesses sn-1 specificity, with polyunsaturated fatty acids at the sn-2 position generating polyunsaturated sn-2-acyl lysophospholipids. Through strategic chemical derivatization, chiral chromatographic separation, and multistage tandem MS, here we first demonstrate that human platelet-type 12-lipoxygenase (12-LOX) can directly catalyze the regioselective and stereospecific oxidation of 2-arachidonoyl-lysophosphatidylcholine (2-AA-LPC) and 2-arachidonoyl-lysophosphatidylethanolamine (2-AA-LPE). Next, we identified these two eicosanoid-lysophospholipids in murine myocardium and in isolated platelets. Moreover, we observed robust increases in 2-AA-LPC, 2-AA-LPE, and their downstream 12-LOX oxidation products, 12(S)-HETE-LPC and 12(S)-HETE-LPE, in calcium ionophore (A23187)-stimulated murine platelets. Mechanistically, genetic ablation of iPLA2γ markedly decreased the calcium-stimulated production of 2-AA-LPC, 2-AA-LPE, and 12-HETE-lysophospholipids in mouse platelets. Importantly, a potent and selective 12-LOX inhibitor, ML355, significantly inhibited the production of 12-HETE-LPC and 12-HETE-LPE in activated platelets. Furthermore, we found that aging is accompanied by significant changes in 12-HETE-LPC in murine serum that were also markedly attenuated by iPLA2γ genetic ablation. Collectively, these results identify previously unknown iPLA2γ-initiated signaling pathways mediated by direct 12-LOX oxidation of 2-AA-LPC and 2-AA-LPE. This oxidation generates previously unrecognized eicosanoid-lysophospholipids that may serve as biomarkers for age-related diseases and could potentially be used as targets in therapeutic interventions.


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