x India's index of industrial production shows 3.1 per cent growth in September 2024 By www.newkerala.com Published On :: Wed, 13 Nov 2024 17:48:02 +0530 Full Article
x LTIMindtree expands footprint in US with new innovation facility By www.newkerala.com Published On :: Wed, 13 Nov 2024 18:04:02 +0530 Full Article
x Photocatalytic 1,3-Oxyheteroarylation of Aryl Cyclopropanes with Azine N-oxides By pubs.rsc.org Published On :: Chem. Sci., 2024, Accepted ManuscriptDOI: 10.1039/D4SC06723A, Edge Article Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Doyoung Kim, Hyewon Ju, Wooseok Lee, Sungwoo HongCyclopropanes, valuable C3 building blocks in organic synthesis, possess high strain energy and inherent stability. We present an efficient, environmentally benign 1,3-oxyheteroarylation of aryl cyclopropanes using azine N-oxides as bifunctional...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
x Guest modulating the photoactivity of a titanium-oxide cage By pubs.rsc.org Published On :: Chem. Sci., 2024, Advance ArticleDOI: 10.1039/D4SC04983G, Edge Article Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Dexin Wang, Yanshu Liu, Guanyun Zhang, Menghui Chu, Fangfang Gao, Guanjie Chen, Guo Wang, Chen-Ho Tung, Yifeng WangTi-oxide salicylate clusters with novel biloculate cages and exchangeable guests are reported. The guests influence the physiochemical properties and photocatalytic CO2/epoxide cycloaddition activities of the complexes.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
x Defence Space Agency hosts first ever space exercise 'Antariksha Abhyas - 2024' in Delhi By www.newkerala.com Published On :: Wed, 13 Nov 2024 19:14:02 +0530 Full Article
x Union Education Minister Dharmendra Pradhan urges states to support exam reforms for zero-error entrance test By www.newkerala.com Published On :: Wed, 13 Nov 2024 19:22:01 +0530 Full Article
x Xi leaves China for APEC meeting in Peru: state media By www.thehindu.com Published On :: Wed, 13 Nov 2024 12:55:46 +0530 Chinese leader Xi Jinping travels to Peru for APEC summit amid trade tensions with U.S., inaugurates Chinese-funded port Full Article News
x Iran executes in public a serial rapist convicted in dozens of cases By www.thehindu.com Published On :: Wed, 13 Nov 2024 14:43:02 +0530 Iran’s state media say authorities have executed in public a man convicted of raping dozens of women over two decades Full Article World
x In vitro identification of oridonin hybrids as potential anti-TNBC agents inducing cell cycle arrest and apoptosis by regulation of p21, γH2AX and cleaved PARP By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3674-3694DOI: 10.1039/D4MD00580E, Research ArticleJinhua Ning, Nini Zhan, Zhanpan Wu, Yuzhe Li, Die Zhang, Yadian Shi, Yingxun Zhou, Chuan-Huizi Chen, Wenbin JinOridonin analogue 11a showed significant antitumor efficacy in vitro via cell cycle arrest and apoptosis by regulation of p21, γH2AX and cleaved PARP accumulation, meanwhile, displayed much more stable than oridonin in human plasma.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
x Furoxan–piplartine hybrids as effective NO donors and ROS inducers in PC3 cancer cells: design, synthesis, and biological evaluation By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3778-3794DOI: 10.1039/D4MD00281D, Research ArticleCarolyne Brustolin Braga, Julio Cesar Milan, Matheus Andrade Meirelles, Bruno Zavan, Guilherme Álvaro Ferreira-Silva, Ester Siqueira Caixeta, Marisa Ionta, Ronaldo A. PilliA novel hybrid integrating piplartine with a furoxan moiety exhibited a sub-micromolar IC50 and extraordinary selectivity for PC3 cells, which was associated with its capacity to release NO, generate ROS, induce DNA damage, and trigger apoptosis.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
x Discovery of hybrid Glypromate conjugates with neuroprotective activity against paraquat-induced toxicity By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3711-3727DOI: 10.1039/D4MD00584H, Research ArticleSara C. Silva-Reis, Vera M. Costa, Daniela Correia da Silva, David M. Pereira, Xavier Cruz Correia, Xerardo García-Mera, José E. Rodríguez-Borges, Ivo E. Sampaio-DiasA series of bicyclic-based Glypromate conjugates with reduction of protein aggregation elicited by Aβ25–35 and neuroprotective activity against paraquat-induced toxicity is reported, paving the way for the discovery of novel neurotherapeutics.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
x Pyridinyl 4-(2-oxoalkylimidazolidin-1-yl)benzenesulfonates and their hydrochloride salts as novel water soluble antimitotic prodrugs bioactivated by cytochrome P450 1A1 in breast cancer cells By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3728-3745DOI: 10.1039/D4MD00476K, Research ArticleVincent Ouellette, Chahrazed Bouzriba, Atziri Corin Chavez Alvarez, Quentin Bruxelles, Geneviève Hamel-Côté, Sébastien FortinNew water soluble antimitotic CYP1A1-activated prodrugs named PYRAIB-SOs and their hydrochlorides targeting breast cancers.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
x Fexinidazole optimization: enhancing anti-leishmanial profile, metabolic stability and hERG safety By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3837-3852DOI: 10.1039/D4MD00426D, Research ArticleAbdrrahman Shemsu Surur, Chin Fung Chan, Frieda-Marie Bartz, Iris L. K. Wong, Van T. D. Nguyen, Lukas Schulig, Andreas Link, Tak Hang Chan, Larry M. C. Chow, Patrick J. BednarskiStructure-guided optimization of fexinidazole led to analog (S)-51, a promising lead compound with superior activity, improved metabolic stability, and enhanced hERG safetyThe content of this RSS Feed (c) The Royal Society of Chemistry Full Article
x Asymmetric imidazole-4,5-dicarboxamide derivatives as SARS-CoV-2 main protease inhibitors: design, synthesis and biological evaluation By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3880-3888DOI: 10.1039/D4MD00414K, Research ArticlePhuong Nguyen Hoai Huynh, Phatcharin Khamplong, Minh-Hoang Phan, Thanh-Phuc Nguyen, Phuong Ngoc Lan Vu, Quang-Vinh Tang, Phumin Chamsodsai, Supaphorn Seetaha, Truong Lam Tuong, Thien Y. Vu, Duc-Duy Vo, Kiattawee Choowongkomon, Cam-Van T. VoNovel asymmetric imidazole-4,5-dicarboxamide derivatives were synthesized, evaluated for SARS-CoV-2 MPro inhibitory activity in vitro, and investigated for binding ability in silico.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
x Correction: computational design, synthesis, and assessment of 3-(4-(4-(1,3,4-oxadiazol-2-yl)-1H-imidazol-2-yl)phenyl)-1,2,4-oxadiazole derivatives as effective epidermal growth factor receptor inhibitors: a prospective strategy for anticancer therapy By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3912-3912DOI: 10.1039/D4MD90040E, Correction Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Nilesh Raghunath Khedkar, Milind Sindkhedkar, Alex JosephThe content of this RSS Feed (c) The Royal Society of Chemistry Full Article
x Anticancer potential of copper(I) complexes based on isopropyl ester derivatives of bis(pyrazol-1-yl)acetate ligands By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4MD00610K, Research Article Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Maura Pellei, Carlo Santini, Miriam Caviglia, Jo' Del Gobbo, Chiara Battocchio, Carlo Meneghini, Simone Amatori, Chiara Donati, Eleonora Zampieri, Valentina Gandin, Cristina MarzanoIn this paper, the isopropyl ester derivatives LOiPr and L2OiPr of bis(pyrazol-1-yl)acetic acid and bis(3,5-dimethyl-pyrazol-1-yl)acetic acid were used as chelators for the preparation of the new Cu(I) phosphane complexes 1-4....The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
x Supreme Court stays order for CBI probe into sexual assault of minor in Chennai By www.thehindu.com Published On :: Wed, 13 Nov 2024 13:07:47 +0530 Calls for a list of five to seven direct recruit IPS officers, including three women, who hail from other States but are now serving in Tamil Nadu cadre Full Article Tamil Nadu
x IIT Madras to conduct two-day summit on extended reality By www.thehindu.com Published On :: Wed, 13 Nov 2024 13:19:23 +0530 The aim is to develop academic partnership programmes to boost research in XR or extended reality Full Article Chennai
x Delhi High Court upholds ban on two-wheelers on Expressways By www.thehindu.com Published On :: Wed, 13 Nov 2024 16:18:26 +0530 Two-wheelers, three-wheelers, and other slow-moving vehicles, such as tractors, are prohibited as per the Gazette Notifications dated June 14, 2018, and January 15, 2021 Full Article Delhi
x Sensex, Nifty hit a five-month low By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:11:22 +0530 Fifth straight losing session at the bourses; shares in the midcap, small cap segments plunged harder than large companies’ stocks in what some called ‘correction mode’ Full Article Business
x Mangaluru Junction - CSMT Superfast Express to get LHB coaches in March 2025 By www.thehindu.com Published On :: Wed, 13 Nov 2024 14:25:17 +0530 Train No. 12133 Mumbai CSMT-Mangaluru Junction Superfast Express will get an LHB rake from March 1 while its pairing service, Train No. 12134 Mangaluru Junction-Mumbai CSMT Superfast Express, will get an LHB rake from March 2 Full Article Mangaluru
x Jagan dares govt. to arrest him, says will continue to ‘expose failures’ By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:16:05 +0530 Full Article Andhra Pradesh
x Varun Hospitality announces eco-friendly mixed-use project to replace The Gateway Hotel in Visakhapatnam By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:28:31 +0530 Full Article Andhra Pradesh
x Missile Exhibition Centre inaugurated at DRDL By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:10:16 +0530 Full Article Telangana
x Metro Rail services to be extended to Medchal and other parts of northern Hyderabad under Phase-III: Telangana CM By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:18:36 +0530 Full Article Hyderabad
x Synthesis of MOF-supported Pt catalyst with high electrochemical oxidation activity for methanol oxidation By pubs.rsc.org Published On :: RSC Adv., 2024, 14,36370-36377DOI: 10.1039/D4RA06393G, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Merve Akin, Hatice Kars, Muhammed Bekmezci, Aysenur Aygun, Mert Gul, Guray Kaya, Fatih SenIn this study, Pt and Pt@Ti-MOF NPs catalysts were synthesized by chemical reduction method. Ti-MOF structure was synthesized using the solvothermal method, and the effect of Ti-MOF on methanol oxidation was investigated.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
x KEA opposes fee reduction for recruitment examinations in Karnataka By www.thehindu.com Published On :: Wed, 13 Nov 2024 16:47:00 +0530 Points out that the government does not provide any grant for conducting recruitment examinations Full Article Karnataka
x Experimental Fortification Lab Centre opened at KLE By www.thehindu.com Published On :: Wed, 13 Nov 2024 18:53:06 +0530 Full Article Karnataka
x Illegal export of iron ore from Belekeri port: Karnataka High Court suspends sentence and grants bail to MLA Satish Sail and five other convicts By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:21:10 +0530 Full Article Karnataka
x ‘Freelance journalist’ held for extortion in Rein Bazaar By www.thehindu.com Published On :: Wed, 13 Nov 2024 20:21:15 +0530 Full Article Telangana
x KSRTC invites EoI to ready commercial complex at Ernakulam depot By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:00:29 +0530 Full Article Kerala
x Exploring urban ecology through stories, verse and flavours By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:27:29 +0530 Full Article Bengaluru
x Gokaldas Exports posts 19% growth in Q2 net profit By www.thehindu.com Published On :: Wed, 13 Nov 2024 22:28:34 +0530 Full Article Business
x 80% of non-executive directors believe existing practices, structures are inadequate to oversee AI: Gartner By www.thehindu.com Published On :: Wed, 13 Nov 2024 23:03:00 +0530 Full Article Business
x Centre plans QCO for weaving machines from next year By www.thehindu.com Published On :: Wed, 13 Nov 2024 23:09:19 +0530 Full Article Business
x Surprise spike: On the Consumer Price Index By www.thehindu.com Published On :: Thu, 14 Nov 2024 00:20:00 +0530 October’s inflation pace surpasses expectations and dashes rate cut hopes for now Full Article Editorial
x Fifty years ago | Tamil Nadu omnibus tax increase held valid By www.thehindu.com Published On :: Thu, 14 Nov 2024 04:35:00 +0530 Full Article Archives
x Private college lecturer arrested for sexual assault on job aspirant in Coimbatore By www.thehindu.com Published On :: Wed, 13 Nov 2024 22:30:13 +0530 Full Article Coimbatore
x How the Supreme Court clamped down on ‘bulldozer’ demolition drives | Explained By www.thehindu.com Published On :: Wed, 13 Nov 2024 22:32:43 +0530 The top court has issued a slew of guidelines aimed at ensuring institutional accountability to curb retributive demolitions by state authorities Full Article India
x UPPSC aspirants protest continues for third day over exam format By www.thehindu.com Published On :: Wed, 13 Nov 2024 22:35:28 +0530 The job aspirants protest multiple shifts and score normalisation in exams, demanding a fair and unified testing process Full Article Uttar Pradesh
x CMC organises exhibition and poster competition on diabetes By www.thehindu.com Published On :: Wed, 13 Nov 2024 23:12:15 +0530 Full Article Tamil Nadu
x Temple sets example by introducing ‘mechanical elephant’ to honour tradition and preserve wildlife By www.thehindu.com Published On :: Wed, 13 Nov 2024 23:41:12 +0530 Inspired by the Irinjadappilly Sri Krishna Temple in Thrissur, the temple trustees collaborated with PETA to bring Sankaranarayan to Kannur Full Article Kerala
x Six men held for online share trading scam By www.thehindu.com Published On :: Thu, 14 Nov 2024 00:01:05 +0530 Full Article Chennai
x India’s tea, sugar exports raise sustainability concerns at home | Explained By www.thehindu.com Published On :: Thu, 14 Nov 2024 05:30:00 +0530 Exports help strengthen India’s economy by increasing revenue but the rapid surge in exports poses multiple challenges to the sustainability of production, processing, and distribution systems Full Article Environment
x Playgrounds in Bengaluru: A mixed bag for parents and children By www.thehindu.com Published On :: Thu, 14 Nov 2024 06:50:00 +0530 Full Article Karnataka
x Defence Space Agency conducts maiden tabletop exercise ‘Antariksha Abhyas’ By www.thehindu.com Published On :: Thu, 14 Nov 2024 07:19:00 +0530 One of the aims of the exercise was also to identify vulnerabilities in conduct of operations in the event of denial or disruptions of space-based services Full Article India
x Lanthanum-doped nickel-based composite metal oxide catalyst for hydrogenation of isophthalonitrile to produce meta-xylenediamine By pubs.rsc.org Published On :: Catal. Sci. Technol., 2024, Advance ArticleDOI: 10.1039/D4CY00802B, PaperHeng Shao, Jing Guo, Rulong Li, Dekun Ji, Long Huang, Haibin ChuLanthanum-doped nickel-based composite metal oxide catalysts exhibited excellent activity in IPN hydrogenation reactions with remarkable stability in fixed-bed reactors.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
x This week's sponsor: ADOBE XD By synd.co Published On :: 2016-11-14T05:01:00+00:00 ADOBE XD BETA, the only all-in-one solution for designing, prototyping, and sharing experiences for websites and mobile apps. Full Article
x Andhra Pradesh Government will fill all vacant teacher posts next year: Minister Nara Lokesh By www.thehindu.com Published On :: Wed, 13 Nov 2024 15:31:04 +0530 Nara Lokesh said that of the 22,542 posts notified in 1998 DSC, 18,008 candidates were given appointment in 1999 Full Article Andhra Pradesh
x Visakhapatnam-Gunupur express to be cancelled on some days from November 13 owing to traffic blocks By www.thehindu.com Published On :: Wed, 13 Nov 2024 15:53:57 +0530 The cancellation is owing to traffic blocks in the Naupada-Gunupur section of Waltair Division Full Article Visakhapatnam
