sla Islamic radicalisation in Central Asia By www.chathamhouse.org Published On :: Tue, 20 Aug 2024 15:47:13 +0000 Islamic radicalisation in Central Asia 18 September 2024 — 10:00AM TO 11:30AM Anonymous (not verified) 20 August 2024 Chatham House and Online Experts analyse rising foreign recruitment, current counter-radicalisation efforts and challenge past Chatham House predictions made of the Central Asia region. In 2014, Chatham House released a report titled The Myth of Post-Soviet Muslim Radicalisation in the Central Asian Republics. At that time, a significant, Western-funded counter-radicalisation industry was addressing what was believed to be a major issue of Islamic violent extremism in the region.Over the past decade, two key developments have occurred. First, Western interest in the region has declined in favour of traditional geopolitical concerns. Second, while violent extremism incidents within Central Asia remain rare, there has been a notable recruitment of Central Asians by foreign groups, with several attacks carried out by Central Asians overseas.In this event, the original report’s authors, John Heathershaw and David Montgomery, will discuss whether the report’s arguments are still valid and how we might answer these questions today.This raises several questions:What did the report accurately predict, and where did it fall short?How can we explain the lack of violent extremist organisations (VEOs) within Central Asia but the presence of Central Asians in VEOs abroad?Could repression by Central Asian states both domestically and transnationally have contributed to this issue?What, if anything, can the counter-radicalisation industry do today to address this problem more effectively?Please note that in-person places are limited. Please wait for confirmation before participating. Full Article
sla FUS contributes to mTOR-dependent inhibition of translation [Signal Transduction] By www.jbc.org Published On :: 2020-12-25T00:06:31-08:00 The amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD)–linked RNA-binding protein called FUS (fused in sarcoma) has been implicated in several aspects of RNA regulation, including mRNA translation. The mechanism by which FUS affects the translation of polyribosomes has not been established. Here we show that FUS can associate with stalled polyribosomes and that this association is sensitive to mTOR (mammalian target of rapamycin) kinase activity. Specifically, we show that FUS association with polyribosomes is increased by Torin1 treatment or when cells are cultured in nutrient-deficient media, but not when cells are treated with rapamycin, the allosteric inhibitor of mTORC1. Moreover, we report that FUS is necessary for efficient stalling of translation because deficient cells are refractory to the inhibition of mTOR-dependent signaling by Torin1. We also show that ALS-linked FUS mutants R521G and P525L associate abundantly with polyribosomes and decrease global protein synthesis. Importantly, the inhibitory effect on translation by FUS is impaired by mutations that reduce its RNA-binding affinity. These findings demonstrate that FUS is an important RNA-binding protein that mediates translational repression through mTOR-dependent signaling and that ALS-linked FUS mutants can cause a toxic gain of function in the cytoplasm by repressing the translation of mRNA at polyribosomes. Full Article
sla Lysine Propionylation and Butyrylation Are Novel Post-translational Modifications in Histones By www.mcponline.org Published On :: 2007-05-01 Yue ChenMay 1, 2007; 6:812-819Research Full Article
sla Islam, Immigration and Identity in Europe By f1.media.brightcove.com Published On :: Wed, 23 May 2018 00:00:00 +0100 Full Article
sla A Divided Island: Sri Lanka's Constitutional Crisis By f1.media.brightcove.com Published On :: Thu, 17 Jan 2019 00:00:00 +0000 Full Article
sla Iran, Islam and Democracy: The Politics of Managing Change 20 Years On By f1.media.brightcove.com Published On :: Tue, 02 Jul 2019 00:00:00 +0100 Full Article
sla Undercurrents: Episode 43 - The UK Election, and Svyatoslav Vakarchuk on the Future of Ukraine By f1.media.brightcove.com Published On :: Thu, 19 Dec 2019 00:00:00 +0000 Full Article
sla Thematic review series: Lipid Posttranslational Modifications. Protein palmitoylation by a family of DHHC protein S-acyltransferases By www.jlr.org Published On :: 2006-06-01 David A. MitchellJun 1, 2006; 47:1118-1127Thematic Reviews Full Article
sla A translation of “classification of four-vectors of an 8-dimensional space”, by Antonyan, L. V., with an appendix by the translator By www.ams.org Published On :: Tue, 01 Oct 2024 14:21 EDT L. Oeding Trans. Moscow Math. Soc. 83 (), 227-250. Abstract, references and article information Full Article
sla Mouse Ifit1b is a cap1-RNA-binding protein that inhibits mouse coronavirus translation and is regulated by complexing with Ifit1c [RNA] By www.jbc.org Published On :: 2020-12-18T00:06:18-08:00 Knockout mouse models have been extensively used to study the antiviral activity of IFIT (interferon-induced protein with tetratricopeptide repeats). Human IFIT1 binds to cap0 (m7GpppN) RNA, which lacks methylation on the first and second cap-proximal nucleotides (cap1, m7GpppNm, and cap2, m7GpppNmNm, respectively). These modifications are signatures of “self” in higher eukaryotes, whereas unmodified cap0-RNA is recognized as foreign and, therefore, potentially harmful to the host cell. IFIT1 inhibits translation at the initiation stage by competing with the cap-binding initiation factor complex, eIF4F, restricting infection by certain viruses that possess “nonself” cap0-mRNAs. However, in mice and other rodents, the IFIT1 orthologue has been lost, and the closely related Ifit1b has been duplicated twice, yielding three paralogues: Ifit1, Ifit1b, and Ifit1c. Although murine Ifit1 is similar to human IFIT1 in its cap0-RNA–binding selectivity, the roles of Ifit1b and Ifit1c are unknown. Here, we found that Ifit1b preferentially binds to cap1-RNA, whereas binding is much weaker to cap0- and cap2-RNA. In murine cells, we show that Ifit1b can modulate host translation and restrict WT mouse coronavirus infection. We found that Ifit1c acts as a stimulatory cofactor for both Ifit1 and Ifit1b, promoting their translation inhibition. In this way, Ifit1c acts in an analogous fashion to human IFIT3, which is a cofactor to human IFIT1. This work clarifies similarities and differences between the human and murine IFIT families to facilitate better design and interpretation of mouse models of human infection and sheds light on the evolutionary plasticity of the IFIT family. Full Article
sla Heme oxygenase-2 is post-translationally regulated by heme occupancy in the catalytic site [Protein Structure and Folding] By www.jbc.org Published On :: 2020-12-11T00:06:20-08:00 Heme oxygenase-2 (HO2) and -1 (HO1) catalyze heme degradation to biliverdin, CO, and iron, forming an essential link in the heme metabolism network. Tight regulation of the cellular levels and catalytic activities of HO1 and HO2 is important for maintaining heme homeostasis. HO1 expression is transcriptionally regulated; however, HO2 expression is constitutive. How the cellular levels and activity of HO2 are regulated remains unclear. Here, we elucidate the mechanism of post-translational regulation of cellular HO2 levels by heme. We find that, under heme-deficient conditions, HO2 is destabilized and targeted for degradation, suggesting that heme plays a direct role in HO2 regulation. HO2 has three heme binding sites: one at its catalytic site and the others at its two heme regulatory motifs (HRMs). We report that, in contrast to other HRM-containing proteins, the cellular protein level and degradation rate of HO2 are independent of heme binding to the HRMs. Rather, under heme deficiency, loss of heme binding to the catalytic site destabilizes HO2. Consistently, an HO2 catalytic site variant that is unable to bind heme exhibits a constant low protein level and an enhanced protein degradation rate compared with the WT HO2. Finally, HO2 is degraded by the lysosome through chaperone-mediated autophagy, distinct from other HRM-containing proteins and HO1, which are degraded by the proteasome. These results reveal a novel aspect of HO2 regulation and deepen our understanding of HO2's role in maintaining heme homeostasis, paving the way for future investigation into HO2's pathophysiological role in heme deficiency response. Full Article
sla Post-translational control of the long and winding road to cholesterol [Lipids] By www.jbc.org Published On :: 2020-12-18T00:06:18-08:00 The synthesis of cholesterol requires more than 20 enzymes, many of which are intricately regulated. Post-translational control of these enzymes provides a rapid means for modifying flux through the pathway. So far, several enzymes have been shown to be rapidly degraded through the ubiquitin–proteasome pathway in response to cholesterol and other sterol intermediates. Additionally, several enzymes have their activity altered through phosphorylation mechanisms. Most work has focused on the two rate-limiting enzymes: 3-hydroxy-3-methylglutaryl CoA reductase and squalene monooxygenase. Here, we review current literature in the area to define some common themes in the regulation of the entire cholesterol synthesis pathway. We highlight the rich variety of inputs controlling each enzyme, discuss the interplay that exists between regulatory mechanisms, and summarize findings that reveal an intricately coordinated network of regulation along the cholesterol synthesis pathway. We provide a roadmap for future research into the post-translational control of cholesterol synthesis, and no doubt the road ahead will reveal further twists and turns for this fascinating pathway crucial for human health and disease. Full Article
sla The Translation of Dosimetry into Clinical Practice: What It Takes to Make Dosimetry a Mandatory Part of Clinical Practice By jnm.snmjournals.org Published On :: 2024-09-05T07:37:49-07:00 Full Article
sla FAP and PSMA Expression by Immunohistochemistry and PET Imaging in Castration-Resistant Prostate Cancer: A Translational Pilot Study By jnm.snmjournals.org Published On :: 2024-10-30T08:04:15-07:00 Visual Abstract Full Article
sla CD70-Targeted Immuno-PET/CT Imaging of Clear Cell Renal Cell Carcinoma: A Translational Study By jnm.snmjournals.org Published On :: 2024-11-07T04:28:31-08:00 Visual Abstract Full Article
sla Temporal Quantitative Proteomics of mGluR-induced Protein Translation and Phosphorylation in Neurons By www.mcponline.org Published On :: 2020-12-01 Charlotte A. G. H. van GelderDec 1, 2020; 19:1952-1967Research Full Article
sla PTM-Shepherd: analysis and summarization of post-translational and chemical modifications from open search results By www.mcponline.org Published On :: 2020-12-01 Daniel J. GeiszlerDec 1, 2020; 0:TIR120.002216v1-mcp.TIR120.002216Technological Innovation and Resources Full Article
sla Problem Notes for SAS®9 - 66511: A Russian translation shows the same value for two different variables in the Define Value dialog box for the Reply node in SAS Customer Intelligence Studio By Published On :: Mon, 24 Aug 2020 14:23:55 EST In SAS Customer Intelligence Studio, when you add Reply- node variable values in the Define Value dialog box, you might notice that two identically labeled data-grid variables are Full Article POLICYOFR+SAS+Real-Time+Decision+Manager
sla Doctors face manslaughter charge for failing to raise alarm over killer nurse By www.bmj.com Published On :: Thursday, December 1, 2016 - 18:06 Full Article
sla Post-translational regulation of the maȷor drug transporters in the families of organic anion transporters and organic anion-transporting polypeptides [Protein Structure and Folding] By www.jbc.org Published On :: 2020-12-11T00:06:21-08:00 The organic anion transporters (OATs) and organic anion–transporting polypeptides (OATPs) belong to the solute carrier (SLC) transporter superfamily and play important roles in handling various endogenous and exogenous compounds of anionic charge. The OATs and OATPs are often implicated in drug therapy by impacting the pharmacokinetics of clinically important drugs and, thereby, drug exposure in the target organs or cells. Various mechanisms (e.g. genetic, environmental, and disease-related factors, drug-drug interactions, and food-drug interactions) can lead to variations in the expression and activity of the anion drug-transporting proteins of OATs and OATPs, possibly impacting the therapeutic outcomes. Previous investigations mainly focused on the regulation at the transcriptional level and drug-drug interactions as competing substrates or inhibitors. Recently, evidence has accumulated that cellular trafficking, post-translational modification, and degradation mechanisms serve as another important layer for the mechanisms underlying the variations in the OATs and OATPs. This review will provide a brief overview of the major OATs and OATPs implicated in drug therapy and summarize recent progress in our understanding of the post-translational modifications, in particular ubiquitination and degradation pathways of the individual OATs and OATPs implicated in drug therapy. Full Article
sla Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane [Research] By www.mcponline.org Published On :: 2020-11-01T00:05:37-07:00 Protein synthesis on the endoplasmic reticulum (ER) requires the dynamic coordination of numerous cellular components. Together, resident ER membrane proteins, cytoplasmic translation factors, and both integral membrane and cytosolic RNA-binding proteins operate in concert with membrane-associated ribosomes to facilitate ER-localized translation. Little is known, however, regarding the spatial organization of ER-localized translation. This question is of growing significance as it is now known that ER-bound ribosomes contribute to secretory, integral membrane, and cytosolic protein synthesis alike. To explore this question, we utilized quantitative proximity proteomics to identify neighboring protein networks for the candidate ribosome interactors SEC61β (subunit of the protein translocase), RPN1 (oligosaccharyltransferase subunit), SEC62 (translocation integral membrane protein), and LRRC59 (ribosome binding integral membrane protein). Biotin labeling time course studies of the four BioID reporters revealed distinct labeling patterns that intensified but only modestly diversified as a function of labeling time, suggesting that the ER membrane is organized into discrete protein interaction domains. Whereas SEC61β and RPN1 reporters identified translocon-associated networks, SEC62 and LRRC59 reporters revealed divergent protein interactomes. Notably, the SEC62 interactome is enriched in redox-linked proteins and ER luminal chaperones, with the latter likely representing proximity to an ER luminal chaperone reflux pathway. In contrast, the LRRC59 interactome is highly enriched in SRP pathway components, translation factors, and ER-localized RNA-binding proteins, uncovering a functional link between LRRC59 and mRNA translation regulation. Importantly, analysis of the LRRC59 interactome by native immunoprecipitation identified similar protein and functional enrichments. Moreover, [35S]-methionine incorporation assays revealed that siRNA silencing of LRRC59 expression reduced steady state translation levels on the ER by ca. 50%, and also impacted steady state translation levels in the cytosol compartment. Collectively, these data reveal a functional domain organization for the ER and identify a key role for LRRC59 in the organization and regulation of local translation. Full Article
sla Asparagine Hydroxylation is a Reversible Post-translational Modification [Research] By www.mcponline.org Published On :: 2020-11-01T00:05:37-07:00 Amino acid hydroxylation is a common post-translational modification, which generally regulates protein interactions or adds a functional group that can be further modified. Such hydroxylation is currently considered irreversible, necessitating the degradation and re-synthesis of the entire protein to reset the modification. Here we present evidence that the cellular machinery can reverse FIH-mediated asparagine hydroxylation on intact proteins. These data suggest that asparagine hydroxylation is a flexible and dynamic post-translational modification akin to modifications involved in regulating signaling networks, such as phosphorylation, methylation and ubiquitylation. Full Article
sla Temporal Quantitative Proteomics of mGluR-induced Protein Translation and Phosphorylation in Neurons [Research] By www.mcponline.org Published On :: 2020-12-01T00:05:33-08:00 At neuronal synapses, activation of group I metabotropic glutamate receptors (mGluR1/5) triggers a form of long-term depression (mGluR-LTD) that relies on new protein synthesis and the internalization of AMPA-type glutamate receptors. Dysregulation of these processes has been implicated in the development of mental disorders such as autism spectrum disorders and therefore merit a better understanding on a molecular level. Here, to study mGluR-induced signaling pathways, we integrated quantitative phosphoproteomics with the analyses of newly synthesized proteins via bio-orthogonal amino acids (azidohomoalanine) in a pulsed labeling strategy in cultured hippocampal neurons stimulated with DHPG, a specific agonist for group I mGluRs. We identified several kinases with important roles in DHPG-induced mGluR activation, which we confirmed using small molecule kinase inhibitors. Furthermore, changes in the AMPA receptor endocytosis pathway in both protein synthesis and protein phosphorylation were identified, whereby Intersectin-1 was validated as a novel player in this pathway. This study revealed several new insights into the molecular pathways downstream of group I mGluR activation in hippocampal neurons, and provides a rich resource for further analyses. Full Article
sla Translating Divergent Environmental Stresses into a Common Proteome Response through Hik33 in a Model Cyanobacterium [Research] By www.mcponline.org Published On :: 2017-05-12T06:53:48-07:00 The histidine kinase Hik33 plays important roles in mediating cyanobacterial response to divergent types of abiotic stresses including cold, salt, high light (HL), and osmotic stresses. However, how these functions are regulated by Hik33 remains to be addressed. Using a hik33-deficient strain (hik33) of Synechocystis sp. PCC 6803 (Synechocystis) and quantitative proteomics, we found that Hik33 depletion induces differential protein expression highly similar to that induced by divergent types of stresses. This typically includes downregulation of proteins in photosynthesis and carbon assimilation that are necessary for cell propagation, and upregulation of heat shock proteins, chaperons, and proteases that are important for cell survival. This observation indicates that depletion of Hik33 alone mimics divergent types of abiotic stresses, and that Hik33 could be important for preventing abnormal stress response in the normal condition. Moreover, we found the majority of proteins of plasmid origin were significantly upregulated in hik33, though their biological significance remains to be addressed. Together, the systematically characterized Hik33-regulated cyanobacterial proteome, which is largely involved in stress responses, builds the molecular basis for Hik33 as a general regulator of stress responses. Full Article
sla PTM-Shepherd: analysis and summarization of post-translational and chemical modifications from open search results [Technological Innovation and Resources] By www.mcponline.org Published On :: 2020-12-01T08:35:18-08:00 Open searching has proven to be an effective strategy for identifying both known and unknown modifications in shotgun proteomics experiments. Rather than being limited to a small set of user-specified modifications, open searches identify peptides with any mass shift that may correspond to a single modification or a combination of several modifications. Here we present PTM-Shepherd, a bioinformatics tool that automates characterization of PTM profiles detected in open searches based on attributes such as amino acid localization, fragmentation spectra similarity, retention time shifts, and relative modification rates. PTM-Shepherd can also perform multi-experiment comparisons for studying changes in modification profiles, e.g. in data generated in different laboratories or under different conditions. We demonstrate how PTM-Shepherd improves the analysis of data from formalin-fixed paraffin-embedded samples, detects extreme underalkylation of cysteine in some datasets, discovers an artefactual modification introduced during peptide synthesis, and uncovers site-specific biases in sample preparation artifacts in a multi-center proteomics profiling study. Full Article
sla Review: Islam's role in shaping Europe By www.chathamhouse.org Published On :: Tue, 01 Feb 2022 17:14:02 +0000 Review: Islam's role in shaping Europe The World Today rsoppelsa.drupal 1 February 2022 Maryyum Mehmood on a work that recasts the role of Muslim minorities Muslims and the Making of Modern EuropeEmily Greble, Oxford University Press, £26.99 When discussing the historical role of Muslims in Europe, most authors focus on Muslims in the western part of the continent, many of whom arrived as immigrant settlers from Muslim-majority nations. As a result, Muslims are easily identifiable as a foreign ‘other’. Emily Greble takes a different trajectory. In Muslims and the Making of Modern Europe, Greble centres her analysis on south-eastern European Muslims who are native to the region and, despite this fact, have still been subject to continuous stigmatization. In light of the present-day political tensions and targeted attacks on Muslims in Bosnia, which has seen inter-ethnic and religious hostility at its worst in 30 years, Greble’s nuanced retelling of the region’s social and political landscape has renewed urgency. Her work serves as a refreshing intervention to the literature on various fronts. It subverts stereotypical assumptions promulgated by the ‘Eastern Question’, whereby Muslims are portrayed as a simple ethnic minority living under colonial rule. Instead, Greble shows how they are a marginalized indigenous group that is by no means a monolithic, homogeneous entity. By uncovering the history of the region through the lens of Muslims, Greble highlights their capabilities as agents of change. Muslims were not just passive subjects but active citizens whose engagement was vital in the framing of social norms, political, ethical and legislative structures. By uncovering the history of the region through the lens of Muslims, Greble highlights their capabilities as agents of change Greble’s neatly crafted thesis serves as a counterpunch to a decades-long clash-of-civilizations discourse, which pits Muslims of the region as Ottoman outsiders to be scapegoated as and when deemed necessary. The author offers a proposition that while secularism was the overarching aim of the new European state-project, the role of religion, especially marginalized or ‘othered’ religious communities cannot be overlooked or relegated to a simple ‘minority’ issue. This argument is laid out in three historical parts, beginning with the post-Ottoman transition of power (1878-1921), to the Yugoslav nation-building project (1918-1941) and finally to the political overhaul in a post-Second World War Europe (1941-1949). Most historical analyses of the region focus on state actions towards Muslim minorities. Greble points out that such an approach is lacking because it is riddled with institutional biases from the very sources and methods used to understand them. Instead, the author takes Muslims, their lived realities and agency as her starting point and effectively manages to avoid such pitfalls. What is most remarkable about this book is Greble’s self-reflective approach to confronting such a sensitive topic with great care. The reader is shown how Muslims affected change and steered the trajectory of democracies in Europe at key historical junctures Almost every chapter begins with an insightful and deeply personal historical account from a Muslim from the region which sets the scene for Greble’s assessment of key social, political and legal struggles. With an enriching methodology, Greble explores the topic through first and second-hand accounts of how Muslims manoeuvred in both the secular realm and within religious spaces, such as madrasas (Islamic seminaries), waqfs (local community funds), muftis and ulemas (religious scholar), and the shariah courts. As a result, the reader is shown how Muslims affected change and steered the trajectory of constitutional democracies in Europe at key historical junctures. By taking this lens, Greble does not just offer another retelling of the significance of the 1878 Congress of Berlin, which enabled the demarcation of new territorial boundaries in a post-Ottoman world, but also conveys the story of how Muslims contributed to the emerging narratives around citizenship. Crucially, we are exposed to Muslim leadership as more than just a docile, homogenous grouping, but a defining entity that shaped the European citizenship project by refashioning both imperial secular norms, as well as Islamic jurisprudential rulings to suit their unique context, as opposed to a remnant of bygone Ottoman rule. A fundamental difference that sets this book apart from other contemporary work on the topic is that the author brings forth multiple intra-faith complexities found within Muslim groups of the region, from revivalist to reformists, and all else in between. The fluctuating relationship between the traditionalist ulema, muftis and qadis (religious scholars, clergy and judges) and the secular state powers is intricately captured across most chapters in this book. At times, the ulema would be seen to bandy with the state to acculturate Muslims to the emerging polities of the region. As Greble shows, muftis in 1914 travelled across southern Serbia giving dawah (missionary work) to locals to encourage them to support the Serbian state. Similarly, qadis in Montenegro in 1902 reassured local Muslims that by following the law of the land, they would be guaranteed their ‘shariah rights’, which were loosely defined by the Muslim clergy. This created a paradox for the states: the role of nation-building and liberalizing orthodox religious communities was given to conservative clerics who, in turn, were gatekeepers setting the boundaries and thus interpreted and applied Islam to preserve their position of power. The consequences were twofold. As Greble suggests, ‘instead of becoming more tied to secular structures of state and society – through centralized law, conscription, political representation – Muslims in formerly Ottoman lands were becoming more deeply bound to Islam’. Simultaneously, the rhetoric used further embedded Muslims firmly as a minority. Ironically in contrast, it was the liberal reformist thinkers who, sometimes, stood in opposition to the state regimes. Such internal divisions within Muslim spaces became more overtly discernible under communist rule, wherein members of the same Muslim community fought in different camps. The author offers a complex perspective not only of Balkan Muslims and their lived experiences, but also, their impact upon wider society and the states themselves For instance, the author notes how some were aligned with the communist regime, while others were fighting with the allied forces and many were still backing revivalist Islamic groups. In light of this, what is perhaps most intriguing is how the communist takeover in 1945 managed to tear down any seemingly progressive movement that benefited the region’s Muslims. And it brought them back to square one, with the scrapping of shariah law and the removal of a mufti-led judiciary. Such crackdowns caused greater frenzy among the region’s Muslims and led to resistance movements in the form of activism and insurgencies. Ultimately, the author offers a complex perspective not only of Balkan Muslims and their lived experiences, but also, the implications of this upon wider society and the states themselves. Greble’s remapping of the historical underpinnings of the tale of Muslims and the Making of Modern Europe is not just a clear example of how Muslims are not a foreign entity to the region, but a call to overturn the entrenched Great Replacement theory which uses this foreign ‘othering’ to further prejudice and calls for the ousting of Muslims and other minorities from Europe, a land which has forever been their home. Full Article
sla Australia to legislate social media ban for those under 16 By www.upi.com Published On :: Thu, 07 Nov 2024 00:54:48 -0500 Australian Prime Minister Anthony Albanese said Thursday his government will introduce legislation to ban children under 16 years of age from social media. Full Article
sla Tesla regains $1 trillion in market capitalization in post-election surge By www.upi.com Published On :: Fri, 08 Nov 2024 12:37:28 -0500 Tesla Friday reached a $1 trillion market capitalization value for the first time since 2022 in a post-election stock rally. Full Article
sla Costco recalls nearly 80,000 pounds of butter due to possible mislabeling By www.upi.com Published On :: Tue, 12 Nov 2024 16:31:56 -0500 Costco voluntarily recalled 79,200 pounds of two types of its store-brand butter over the past month because their labels may not have said the products contain milk. Full Article
sla Costco recalls nearly 80,000 pounds of butter due to possible mislabeling By www.upi.com Published On :: Tue, 12 Nov 2024 16:31:56 -0500 Costco voluntarily recalled 79,200 pounds of two types of its store-brand butter over the past month because their labels may not have said the products contain milk. Full Article
sla Watch: Rhode Island man amasses world's largest collection of energy drink cans By www.upi.com Published On :: Fri, 08 Nov 2024 14:52:40 -0500 A Rhode Island man with a passion for caffeine earned a Guinness World Record for his collection of 1,019 energy drink cans. Full Article
sla The ‘Flavodiet’ Could Slash Your Dementia Risk By 30% (M) By www.spring.org.uk Published On :: Fri, 01 Nov 2024 18:00:05 +0000 A study reveals how six simple food additions could dramatically lower your dementia risk. Full Article Dementia Nutrition subscribers-only
sla $11B budget package passes Pennsylvania Legislature By www.edweek.org Published On :: Mon, 23 Nov 2020 00:00:00 +0000 Full Article Pennsylvania
sla Adoption of New Science Standards May Start With Rhode Island By blogs.edweek.org Published On :: Thu, 16 May 2013 00:00:00 +0000 Rhode Island may become the first state to adopt the Next Generation Science Standards. Full Article Rhode_Island
sla Science Standards Win OK in First State With Rhode Island Vote By blogs.edweek.org Published On :: Thu, 23 May 2013 00:00:00 +0000 Rhode Island today became the first state in the nation adopt the Next Generation Science Standards. Full Article Rhode_Island
sla Per-Pupil Spending in Rhode Island Schools (Map) By www.edweek.org Published On :: Tue, 27 Feb 2018 00:00:00 +0000 This map of Rhode Island shows per-pupil spending by school and just how much spending varies among the schools within individual districts. Full Article Rhode_Island
sla New Science Standards to Face First State Vote Today, in Rhode Island By blogs.edweek.org Published On :: Thu, 23 May 2013 00:00:00 +0000 Rhode Island may become the first state to adopt the Next Generation Science Standards. The state board will vote later today. Full Article Rhode_Island
sla Michigan, Rhode Island to Require Education About Genocide in Schools By blogs.edweek.org Published On :: Wed, 29 Jun 2016 00:00:00 +0000 The two states are the first in 20 years to add such a requirement. Full Article Rhode_Island
sla Rhode Island PARCC Scores Lower on Computer-Based Exams By blogs.edweek.org Published On :: Tue, 09 Feb 2016 00:00:00 +0000 A state-by-state breakdown shows that Colorado, Rhode Island and Illinois found some evidence that students' familiarity with technology impacted scores on 2014-15 PARCC exams. An analysis in Maryland is pending. Full Article Rhode_Island
sla Rhode Island Announces Statewide K-12 Personalized Learning Push By blogs.edweek.org Published On :: Wed, 22 Feb 2017 00:00:00 +0000 The Chan-Zuckerberg Initiative and other funders are supporting Rhode Island's efforts to define and research personalized learning in traditional public schools. Full Article Rhode_Island
sla Rhode Island to Promote Blended Learning Through Nonprofit Partnership By blogs.edweek.org Published On :: Fri, 08 Aug 2014 00:00:00 +0000 The Rhode Island Department of Education and the nonprofit Learning Accelerator are teaming to develop a strategic plan and a communications strategy aimed at expanding blended learning. Full Article Rhode_Island
sla Rhode Island Jumps on 'Computer Science for All' Bandwagon By blogs.edweek.org Published On :: Tue, 08 Mar 2016 00:00:00 +0000 Rhode Island Governor Gina M. Raimondo announced a new effort to bring computer science classes to every public school in the state by the end of 2017. Full Article Rhode_Island
sla New Rhode Island Law Mandates Daily School Recess, Calls It a Student's Right By blogs.edweek.org Published On :: Fri, 08 Jul 2016 00:00:00 +0000 The law passed after parent groups lobbied for it and will require schools to provide 20 consecutive minutes of recess daily for students in kindergarten through 6th grade. Full Article Rhode_Island
sla Educational Opportunities and Performance in Rhode Island By www.edweek.org Published On :: Wed, 16 Jan 2019 00:00:00 +0000 This Quality Counts 2019 Highlights Report captures all the data you need to assess your state's performance on key educational outcomes. Full Article Rhode_Island
sla Rhode Island the Latest State to Plan a District Intervention By www.edweek.org Published On :: Wed, 21 Aug 2019 00:00:00 +0000 The move to assume broad powers over the Providence school system illustrates both the attraction and challenges of high-profile approaches to troubled or low-performing schools and districts. Full Article Rhode_Island
sla Educational Opportunities and Performance in Rhode Island By www.edweek.org Published On :: Tue, 21 Jan 2020 00:00:00 +0000 This Quality Counts 2020 Highlights Report captures all the data you need to assess your state's performance on key educational outcomes. Full Article Rhode_Island
sla State Legislators Revamp Funding in Texas, Nevada By www.edweek.org Published On :: Tue, 18 Jun 2019 00:00:00 +0000 Several states this year sought to replace their funding formulas, a monumental fiscal and political feat, but only a handful of legislatures have been able to get proposals to their governors' desks. Full Article Nevada
sla Civics-Test Bills Hit State Legislatures Again in 2016 By blogs.edweek.org Published On :: Thu, 14 Jan 2016 00:00:00 +0000 A bill in Nebraska would require high school students to take a civics examination before graduating. Full Article Nebraska
sla $11B budget package passes Pennsylvania Legislature By www.edweek.org Published On :: 2020-11-23T08:45:20-05:00 Full Article Education
sla Hawaii Lawmakers Propose Legislation to Create Housing Vouchers for Teachers By www.edweek.org Published On :: Tue, 26 Feb 2019 00:00:00 +0000 Two proposed bills are intended to create a housing-voucher program for full-time teachers employed by the Hawaii education department or at public charter schools. Full Article Hawaii