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Enlightening advances in polymer bioconjugate chemistry: light-based techniques for grafting to and from biomacromolecules

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Published On ::

Chem. Sci., 2020, Advance Article
DOI: 10.1039/D0SC01544J, Perspective
Open Access
Rebecca A. Olson, Angie B. Korpusik, Brent S. Sumerlin
Light-driven synthetic techniques have revolutionized polymer–biomacromolecule conjugation. This Perspective discusses the benefits of photochemistry for polymer–protein ligation and considerations when designing a new light-driven conjugation approach.
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Trends in biomedical research Mieczyslaw Pokorski, editor

By library.mit.edu
Published On :: Sun, 5 Apr 2020 06:39:21 EDT

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Statistical modeling in biomedical research: contemporary topics and voices in the field / Yichuan Zhao, Ding-Geng (Din) Chen, editors

By library.mit.edu
Published On :: Sun, 26 Apr 2020 07:06:33 EDT

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[ASAP] A Community Letter Regarding Sharing Biomolecular Simulation Data for COVID-19

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Published On :: Fri, 01 May 2020 04:00:00 GMT

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00319


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Cognitive informatics in health and biomedicine: understanding and modeling health behaviors / Vimla L. Patel, Jose F. Arocha, Jessica S. Ancker, editors

By library.mit.edu
Published On :: Sun, 30 Jul 2017 06:29:46 EDT

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Understanding host-microbiome interactions -- an omics approach: omics of host-microbiome association / Ravindra Pal Singh, Ramesh Kothari, Prakash G. Koringa, Satya Prakash Singh, editors

By library.mit.edu
Published On :: Sun, 22 Oct 2017 06:29:07 EDT

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Biomarkers in psychiatry / Judith Pratt, Jeremy Hall, editors

By library.mit.edu
Published On :: Sun, 17 Feb 2019 13:12:16 EST

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Mathematical Modelling and Biomechanics of the Brain Corina Drapaca, Siv Sivaloganathan

By library.mit.edu
Published On :: Sun, 13 Oct 2019 07:39:15 EDT

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Enantiomeric Copper Based Anticancer Agents Promoting Sequence-Selective Cleavage of G-Quadruplex Telomeric DNA and non-random cleavage of plasmid DNA

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Metallomics, 2020, Accepted Manuscript
DOI: 10.1039/D0MT00084A, Paper
Sabiha Parveen, J. A. Cowan, Zhen Yu, Farukh Arjmand
Copper-based binuclear enantiomeric complexes 1S and 1R were synthesized as anticancer chemotherapeutic agents to target G-quadruplex rich region of DNA and thoroughly characterized by various spectroscopic and single X-ray crystal...
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Science Podcast - Biomechanics of fruitflies on the wing and a news roundup (11 April 2014)

By traffic.omny.fm
Published On :: Fri, 11 Apr 2014 12:00:00 -0400

Fruitflies take evasive action; roundup of daily news with David Grimm.


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The home microbiome and a news roundup (29 August 2014)

By traffic.omny.fm
Published On :: Fri, 29 Aug 2014 12:00:00 -0400

Sharing microbes around the house; roundup of daily news.


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Genes and the human microbiome and a news roundup

By traffic.omny.fm
Published On :: Thu, 10 Sep 2015 14:00:00 -0400

Seth Bordenstein discusses how our genes affect the composition of our microbiome, influencing our health, and David Grimm talks with Sarah Crespi about the origins of the Basque language, the benefits of being raised in a barn, and how some flying ants lost their wings. Hosted by Susanne Bard. [Image credit: Decaseconds/CC BY-NC 2.0, via flickr


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What hunter-gatherer gut microbiomes have that we don’t, and breaking the emoji code

By traffic.omny.fm
Published On :: Thu, 24 Aug 2017 15:45:00 -0400

Sarah Crespi talks to Sam Smits about how our microbial passengers differ from one culture to the next—are we losing diversity and the ability to fight chronic disease? For our books segment, Jen Golbeck talks with Vyvyan Evans about his book The Emoji Code: The Linguistics Behind Smiley Faces and Scaredy Cats. Listen to previous podcasts. [Image: Woodlouse/Flickr; Music: Jeffrey Cook]


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Treating the microbiome, and a gene that induces sleep

By traffic.omny.fm
Published On :: Thu, 31 Jan 2019 14:45:00 -0500

Orla Smith, editor of Science Translational Medicine joins host Sarah Crespi to talk about what has changed in the past 10 years of microbiome research, what’s getting close to being useful in treatment, and how strong, exactly, the research is behind those probiotic yogurts. When you’re sick, sleeping is restorative—it helps your body recover from nasty infections. Meagan Cantwell speaks with Amita Sehgal, professor of neuroscience at the University of Pennsylvania and an investigator at Howard Hughes Medical Institute in Chevy Chase, Maryland, about the process of discovering a gene in fruit flies that links sleep and immune function. This week’s episode was edited by Podigy. Download the transcript (PDF) Listen to previous podcasts. About the Science Podcast [Music: Jeffrey Cook]


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Where our microbiome came from, and how our farming and hunting ancestors transformed the world

By traffic.omny.fm
Published On :: Thu, 29 Aug 2019 14:45:00 -0400

Micro-organisms live inside everything from the human gut to coral—but where do they come from? Host Meagan Cantwell talks to Staff Writer Elizabeth Pennisi about the first comprehensive survey of microbes in Hawaii’s Waimea Valley, which revealed that plants and animals get their unique microbiomes from organisms below them in the food chain or the wider environment. Going global, Meagan then speaks with Erle Ellis, professor of geography and environmental science at the University of Maryland, Baltimore County, about a project that aggregated the expertise of more than 250 archaeologists to map human land use over the past 10,000 years. This detailed map will help fine-tune climate models. This week’s episode was edited by Podigy. Ads on this show: Science Sessions Podcast; Kroger Download a transcript (PDF)  Listen to previous podcasts. About the Science Podcast [Image: Chris Couderc/Flickr; Music: Jeffrey Cook]


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Analysis of amino acid enantiomers from aged fingerprints

By feeds.rsc.org
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Anal. Methods, 2020, 12,2052-2057
DOI: 10.1039/D0AY00096E, Technical Note
Open Access
Ward van Helmond, Maarten Weening, Vonne Vleer, Marcel de Puit
The use of the enantiomeric ratio of D/L-serine in fingerprints could pose as interesting target for age estimation techniques.
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Bio-assay of non-amidated progastrin-derived peptide (G17-Gly) using Tailor-made recombinant antibody fragment and phages display method: A biomedical analysis

By feeds.rsc.org
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Anal. Methods, 2020, Accepted Manuscript
DOI: 10.1039/D0AY00627K, Paper
Deniz Sadighbayan, Mohammad Reza Tohid-kia, Tayebeh Mehdipour, Mohammad Hasanzadeh, Ahmad Yari Khosroushahi
In this research, four novel and sensitive immunosensor for electrochemical determination of G17-Gly were designed based on signal amplification and tailor-made recombinant antibody technology. Anti-G17-Glyantibody fragments (i.e. scFv and VL...
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Correction: Towards simultaneous quantification of protease inhibitors and inflammatory biomarkers in serum for people living with HIV

By feeds.rsc.org
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Anal. Methods, 2020, 12,2196-2196
DOI: 10.1039/D0AY90050H, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Pengyi Wang, Charles S. Venuto, Raymond Cha, Benjamin L. Miller
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[ASAP] In Situ Incorporation of Fluorophores in Zeolitic Imidazolate Framework-8 (ZIF-8) for Ratio-Dependent Detecting a Biomarker of Anthrax Spores

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Published On :: Fri, 01 May 2020 04:00:00 GMT

Analytical Chemistry
DOI: 10.1021/acs.analchem.0c00499


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[ASAP] Bifunctional Au@Pt/Au core@shell Nanoparticles As Novel Electrocatalytic Tags in Immunosensing: Application for Alzheimer’s Disease Biomarker Detection

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Published On :: Fri, 01 May 2020 04:00:00 GMT

Analytical Chemistry
DOI: 10.1021/acs.analchem.0c00760


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[ASAP] Zirconium–Metalloporphyrin Frameworks–Luminol Competitive Electrochemiluminescence for Ratiometric Detection of Polynucleotide Kinase Activity

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Published On :: Mon, 04 May 2020 04:00:00 GMT

Analytical Chemistry
DOI: 10.1021/acs.analchem.0c01262


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[ASAP] Metal Ion-Mediated Potential-Resolved Ratiometric Electrochemiluminescence Bioassay for Efficient Determination of miR-133a in Early Diagnosis of Acute Myocardial Infarction

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Published On :: Thu, 07 May 2020 04:00:00 GMT

Analytical Chemistry
DOI: 10.1021/acs.analchem.0c00377


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Medically important plant biomes: source of secondary metabolites / Dilfuza Egamberdieva, Antonio Tiezzi, editors

By library.mit.edu
Published On :: Sun, 22 Dec 2019 07:46:07 EST

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Water hyacinth: a potential lignocellulosic biomass for bioethanol / Anuja Sharma, Neeraj K. Aggarwal

By library.mit.edu
Published On :: Sun, 16 Feb 2020 07:32:02 EST

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The generic unfolding of a biomimetic polymer during force spectroscopy

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Soft Matter, 2020, 16,3941-3951
DOI: 10.1039/C9SM02545F, Paper
Aviel Chaimovich, Christian Leitold, Christoph Dellago
By computing free energies with molecular simulations, we find a general signature for protein unfolding in force spectroscopy, and in turn, we present a useful formula for experimentalists.
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Harnessing biomimetic cryptic bonds to form self-reinforcing gels

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Soft Matter, 2020, Advance Article
DOI: 10.1039/D0SM00145G, Paper
Santidan Biswas, Victor V. Yashin, Anna C. Balazs
Cryptic sites, which lay hidden in folded biomolecules, become exposed by applied force and form new bonds that reinforce the biomaterial.
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Stoichiometry and thermodynamics of metallurgical processes / Y.K. Rao

By prospero.murdoch.edu.au
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Rao, Y. K


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[ASAP] Mechanical Tension of Biomembranes Can Be Measured by Super Resolution (STED) Microscopy of Force-Induced Nanotubes

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Published On :: Wed, 29 Apr 2020 04:00:00 GMT

Nano Letters
DOI: 10.1021/acs.nanolett.9b05232


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[ASAP] Biohybrid Triboelectric Nanogenerator for Label-Free Pharmacological Fingerprinting in Cardiomyocytes

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Published On :: Thu, 30 Apr 2020 04:00:00 GMT

Nano Letters
DOI: 10.1021/acs.nanolett.0c01584


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Biomolecular computation for bionanotechnology / Jian-Qin Liu, Katsunori Shimohara

By prospero.murdoch.edu.au
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Liu, Jian-Qin


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[ASAP] Selective Modification of Tryptophan Residues in Peptides and Proteins Using a Biomimetic Electron Transfer Process

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Published On :: Tue, 05 May 2020 04:00:00 GMT

Journal of the American Chemical Society
DOI: 10.1021/jacs.0c03039


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Biomass to Renewable Energy Processes / edited by Jay Cheng

By library.mit.edu
Published On :: Sun, 21 Apr 2019 06:19:01 EDT

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Biomass gasification, pyrolysis and torrefaction: practical design and theory / Prabir Basu

By library.mit.edu
Published On :: Sun, 19 May 2019 06:18:11 EDT

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Fuel property estimation and combustion process characterization: conventional fuels, biomass, biocarbon, waste fuels, refuse derived fuel, and other alternative fuels / Yen-Hsiung Kiang

By library.mit.edu
Published On :: Sun, 28 Jul 2019 06:49:18 EDT

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Polymer-based additive manufacturing: biomedical applications / Declan M. Devine, editor

By library.mit.edu
Published On :: Sun, 13 Oct 2019 06:22:18 EDT

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Pyrolysis of biomass / Shurong Wang, Zhongyang Luo

By library.mit.edu
Published On :: Sun, 27 Oct 2019 06:20:31 EDT

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Sustainable biofuel and biomass: advances and impacts / edited by Arindam Kuila

By library.mit.edu
Published On :: Sun, 15 Mar 2020 06:23:26 EDT

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Biomass Burning in Sub-Saharan Africa: Chemical Issues and Action Outreach / Liliana Mammino, editor

By library.mit.edu
Published On :: Sun, 15 Mar 2020 06:23:26 EDT

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Handbook on Characterization of Biomass, Biowaste and Related By-Products editor, Ange Nzihou

By library.mit.edu
Published On :: Sun, 5 Apr 2020 06:19:51 EDT

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PEEK biomaterials handbook / edited by Steven M. Kurtz

By library.mit.edu
Published On :: Sun, 19 Apr 2020 06:48:14 EDT

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Biomarkers in Drug Discovery and Development: A Handbook of Practice, Application, and Strategy, 2nd Edition

By www.wiley.com
Published On :: 2020-03-24T04:00:00Z


 
This book continues the legacy of a well-established reference within the pharmaceutical industry – providing perspective, covering recent developments in technologies that have enabled the expanded use of biomarkers, and discussing biomarker characterization and validation and applications throughout drug discovery and development.

•    Explains where proper use of biomarkers can substantively impact drug development timelines and costs, enable selection

Read More...


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Selective modification of Ti6Al4V surfaces for biomedical applications

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RSC Adv., 2020, 10,17642-17652
DOI: 10.1039/C9RA11000C, Paper
Open Access
Gabriela Melo Rodriguez, James Bowen, Mischa Zelzer, Artemis Stamboulis
The surface of a medical implant is required to interact favourably with ions, biomolecules and cells in vivo, commonly resulting in the formation of the extracellular matrix.
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A novel series of phenolic temozolomide (TMZ) esters with 4 to 5-fold increased potency, compared to TMZ, against glioma cells irrespective of MGMT expression

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RSC Adv., 2020, 10,17561-17570
DOI: 10.1039/D0RA02686G, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Leroy Shervington, Oliver Ingham, Amal Shervington
The standard of care treatment for patients diagnosed with glioblastoma multiforme (GBM) is temozolomide (TMZ).
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A highly sensitive, selective and renewable carbon paste electrode based on a unique acyclic diamide ionophore for the potentiometric determination of lead ions in polluted water samples

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RSC Adv., 2020, 10,17552-17560
DOI: 10.1039/D0RA01435D, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
M. A. Zayed, Walaa H. Mahmoud, Ashraf A. Abbas, Aya E. Ali, Gehad G. Mohamed
Due to the toxicity of lead(II) to all living organisms destroying the central nervous system and leading to circulatory system and brain disorders, the development of effective and selective lead(II) ionophores for its detection is very important.
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Biomeasurement : a student's guide to biological statistics / Dawn Hawkins

By prospero.murdoch.edu.au
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Hawkins, Dawn May, author


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Oxaliplatin and [Pt(R,R-DACH)(panobinostat-2H)] show nanomolar cytotoxicity towards diffuse intrinsic pontine glioma (DIPG)

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Dalton Trans., 2020, 49,5703-5710
DOI: 10.1039/C9DT04862F, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Marie H. C. Boulet, Laura K. Marsh, Alison Howarth, Alice Woolman, Nicola J. Farrer
Oxaliplatin and the platinum(II) panobinostat complex (2) demonstrate nanomolar cytotoxicity towards diffuse intrinsic pontine glioma cells (DIPG); with 2 exhibiting improved solubility in comparison to panobinostat.
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Your skin microbiome can be used to predict your age

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Published On :: 20 Feb 2020 23:28:01 +0000

As we age, our skin changes, and so too do the bugs that live there


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DuPont and Dutch firm pursue microbiome therapy

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Published On :: 22 Feb 2020 11:30:14 +0000


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