Every citizen has a legal right to return to their home, says State’s Chief Spokesperson on COVID-19

Asked about the incidents, Additional Chief Secretary (Home) Awanish Awasthi said he that he is aware of them.

First Shramik Special from Chennai Central will reach destination on Monday

The trio were among thousands of migrant workers who have set out on foot for their home states from Maharashtra in the last few weeks amid lockdown on account for coronavirus.

Most entering Madhya Pradesh from Maharashtra are headed to Uttar Pradesh.

Both claim they are footing the bill

Most of them are from West Bengal

It follows letter seeking reimbursement

A select list of stories to read before you start your day

They were atop a heap of mangoes on the Agra-bound vehicle coming from Hyderabad.

An alert loco driver of a goods train saved the lives of at least 20 migrant workers by applying the emergency brakes and halting the train just 100 metres away from them near Pune on Friday evening. The migrants were walking on the tracks between the Uruli and Loni stations. The incident happened barely 14 hrs after 16 migrants were killed on Aurangabad tracks.

Sanjay Raut took to his official Twitter handle on Sunday to let know his suggestion via a post regarding the situation.

Scientists at the Smithsonian Institution examined the feather remains from the Jan. 15, 2009, US Airways Flight 1549 bird strike to determine not only the species, but also that the Canada geese involved were from a migratory, rather than resident, population. This knowledge is essential for wildlife professionals to develop policies and techniques that will reduce the risk of future collisions. The team’s findings were published in the journal “Frontiers in Ecology and the Environment” in June.

The post Scientists Determine Geese Involved in Hudson River Plane Crash Were Migratory appeared first on Smithsonian Insider.

“Our results support the idea that environmental conditions on tropical non-breeding areas can influence the departure time for spring migration,” said Colin Studds, a postdoctoral fellow at the Smithsonian Conservation Biology Institute's Migratory Bird Center and lead author of the study.

The post Smithsonian scientists find declining rainfall is a major influence for migrating birds appeared first on Smithsonian Insider.

The predictability and scale of seasonal changes in a habitat help determine the distance migratory species move and whether the animals always travel together to the same place or independently to different locations.

The post Changes in vegetation determine how animals migrate, scientists find in new National Zoo study appeared first on Smithsonian Insider.

In a new study researchers from the Smithsonian Conservation Biology Institute’s Center for Conservation and Evolutionary Genetics used DNA from coyote scat (feces) to trace the route that led some of the animals to colonize in Northern Virginia.

The post New genetic evidence confirms coyote migration route to Virginia and hybridization with wolves appeared first on Smithsonian Insider.

Small migratory male birds that winter in a stressful environment age faster than those that winter in a high-quality habitat, according to research stemming from […]

The post Small migratory birds age faster in stressful places, study reveals appeared first on Smithsonian Insider.

Unlocking the mysteries of animal migration through precise, near real-time tracking can solve major conservation challenges and transform wildlife science worldwide. For the past year, […]

The post New project to unlock migration mysteries from air appeared first on Smithsonian Insider.

More than two million migrating raptors passed over Panama City on Sunday, Nov. 2, doubling the previous record of almost 900,000 tallied in a single […]

The post Panama shatters raptor migration record appeared first on Smithsonian Insider.

Researchers who examined thousands of migratory birds arriving in the United States from Central and South America have determined that three percent carry ticks species […]

The post Disease carrying ticks hitchhike into U.S. on migratory birds appeared first on Smithsonian Insider.

Laura O'Regan, Giancarlo Barone, Rozita Adib, Chang Gok Woo, Hui Jeong Jeong, Emily L. Richardson, Mark W. Richards, Patricia A.J. Muller, Spencer J. Collis, Dean A. Fennell, Jene Choi, Richard Bayliss, and Andrew M. Fry

EML4-ALK is an oncogenic fusion present in ~5% non-small cell lung cancers. However, alternative breakpoints in the EML4 gene lead to distinct variants with different patient outcomes. Here, we show in cell models that EML4-ALK variant 3 (V3), which is linked to accelerated metastatic spread, causes microtubule stabilization, formation of extended cytoplasmic protrusions and increased cell migration. It also recruits the NEK9 and NEK7 kinase to microtubules via the N-terminal EML4 microtubule-binding region. Overexpression of wild-type EML4 as well as constitutive activation of NEK9 also perturb cell morphology and accelerate migration in a microtubule-dependent manner that requires the downstream kinase NEK7 but not ALK activity. Strikingly, elevated NEK9 expression is associated with reduced progression-free survival in EML4-ALK patients. Hence, we propose that EML4-ALK V3 promotes microtubule stabilization through NEK9 and NEK7 leading to increased cell migration. This represents a novel actionable pathway that could drive metastatic disease progression in EML4-ALK lung cancer.

Stephen Kershaw, David J. Morgan, James Boyd, David G. Spiller, Gareth Kitchen, Egor Zindy, Mudassar Iqbal, Magnus Rattray, Chris M. Sanderson, Andrew Brass, Claus Jorgensen, Tracy Hussell, Laura C. Matthews, and David W. Ray

Glucocorticoids (GCs) act through the glucocorticoid receptor (GR) to regulate immunity, energy metabolism, and tissue repair. Upon ligand binding, activated GR mediates cellular effects by regulating gene expression, but some GR effects can occur rapidly without new transcription. We show GCs rapidly inhibit cell migration, in response to both GR agonist and antagonist ligand binding. The inhibitory effect on migration is prevented by GR knockdown with siRNA, confirming GR specificity, but not by actinomycin D treatment, suggesting a non-transcriptional mechanism. We identified a rapid onset increase in microtubule polymerisation following glucocorticoid treatment, identifying cytoskeletal stabilisation as the likely mechanism of action. HDAC6 overexpression, but not knockdown of αTAT1, rescued the GC effect, implicating HDAC6 as the GR effector. Consistent with this hypothesis, ligand-dependent cytoplasmic interaction between GR and HDAC6 was demonstrated by quantitative imaging. Taken together, we propose that activated GR inhibits HDAC6 function and thereby increases the stability of the microtubule network to reduce cell motility. We therefore report a novel, non-transcriptional mechanism whereby GCs impair cell motility through inhibition of HDAC6 and rapid reorganization of the cell architecture.

Scientists from the Migratory Bird Center of the Smithsonian Conservation Biology Institute are using transmitters to track the movements of shorebirds–the long-billed curlew, red knot, […]

The post Studying migratory connectivity of shorebirds on the Texas coast appeared first on Smithsonian Insider.

Identifying and understanding the migratory connectivity of birds throughout an entire annual cycle (not just the times of year they are in your back yard), […]

The post Video: Protecting songbirds by Better Understanding their Migratory connectivity appeared first on Smithsonian Insider.

Georgi Dimchev
Apr 9, 2020; 133:jcs239020-jcs239020
Articles

Jordi Lambert
Apr 8, 2020; 133:jcs235762-jcs235762
Articles

Immigration benefits the U.S. economy overall and has little negative effect on the income and job opportunities of most native-born Americans, says a new report by a panel of the National Research Council.

As immigrants and their descendants become integrated into U.S. society, many aspects of their lives improve, including measurable outcomes such as educational attainment, occupational distribution, income, and language ability, but their well-being declines in the areas of health, crime, and family patterns, says a new report from the National Academies of Sciences, Engineering, and Medicine.

A new report from the National Academies of Sciences, Engineering, and Medicine provides a comprehensive assessment of economic and demographic trends of U.S. immigration over the past 20 years, its impact on the labor market and wages of native-born workers, and its fiscal impact at the national, state, and local levels.

In President Trump’s address to Congress, he cited a National Academies report on the economic consequences of immigration.

While extreme environmental events — such as floods and tsunamis — may trigger migrations, the underlying drivers of migration are far more complex and diverse, says new research. The research reviewed the available evidence on population movements associated with extreme weather events and found that people could find themselves ‘trapped’ and vulnerable, whether they stayed at their homes or moved to new locations.