lec An overview of electrochemical biosensors used for COVID-19 detection By pubs.rsc.org Published On :: Anal. Methods, 2024, 16,2164-2176DOI: 10.1039/D3AY02042H, MinireviewTatiana Lima Valerio, Raquel Anastácio, Stella Schuster da Silva, Carolina Camargo de Oliveira, Marcio VidottiThis short review presents the latest advances in the field of electrochemical biosensors, focusing particularly on impedimetric biosensors for the direct measurement of analytes.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
lec A novel electrophoretic assisted hydrophobic microdevice for enhancing blood cell sorting: design and numerical simulation By pubs.rsc.org Published On :: Anal. Methods, 2024, 16,2368-2377DOI: 10.1039/D4AY00196F, PaperXinkun Chen, Xueye ChenMicrofluidic technology has great advantages in the precise manipulation of micro–nano particles, and the hybrid microfluidic separation technology has attracted much attention due to the advantages of both active and passive separation technology at the same time.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
lec A highly sensitive and selective fluorescent biosensor for breast cancer derived exosomes using click reaction of azide–CD63 aptamer and alkyne-polymer dots By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00146J, PaperDumei Ma, Yiting Luo, Xiaoya Zhang, Zehu Xie, Yinghua Yan, Chuan-Fan DingA fluorescence method based on Cu-triggered click reaction of azide modified CD63 aptamer and alkyne capped Pdots was developed for breast cancer derived exosome detection.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
lec A reaction based carbazole–indolium conjugate probe for the selective detection of environmentally toxic ions By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00301B, PaperJayasudha Palanisamy, Mansour K. Gatasheh, Ashraf Atef HatamlehCarbazole–indolium based colorimetric probe was designed for detecting cyanide ions in various water samples. An outstanding response was shown by paper test strips prepared using the probe for the easy detection of cyanide in real time.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
lec Electroanalysis overview: additive manufactured biosensors using fused filament fabrication By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00278D, Minireview Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Robert D. Crapnell, Craig E. BanksAdditive manufacturing (3D-printing), in particular fused filament fabrication, presents a paradigm shift in the way electrochemical based biosensing platforms are produced, giving rise to a new generation of personalized and on-demand biosensors.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
lec Design and fabrication of La-based perovskites incorporated with functionalized carbon nanofibers for the electrochemical detection of roxarsone in water and food samples By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00264D, PaperMariya Antony John Felix, Santhiyagu Sahayaraj Rex Shanlee, Shen-Ming Chen, Sundaresan Ruspika, Ramachandran Balaji, Narendhar Chandrasekar, Periyanayagam Arockia DossFabrication of potent electrocatalyst, La-based perovskites coupled with functionalized carbon nanofibers (LMO/f-CNF) for ultrasensitive electrochemical detection of roxarsone in edible and water samples.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
lec A highly selective probe engineered to detect polarity and distinguish normal cells and tumor cells in tissue sections By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00438H, PaperSai Zhu, Lixuan Dai, Xiaoli Zhong, Weiying LinWe have designed a polarity fluorescent probe (DCI-Cou-polar) with high selectivity for diagnosing cancer.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
lec Down to the wire: On the run-up to the U.S. presidential election By www.thehindu.com Published On :: Tue, 17 Sep 2024 00:30:00 +0530 The U.S. presidential race is poised on a knife’s edge Full Article Editorial
lec Wrong notion: On simultaneous elections By www.thehindu.com Published On :: Fri, 20 Sep 2024 00:10:00 +0530 The idea of simultaneous elections is inherently anti-federal Full Article Editorial
lec Sri Lanka’s verdict: On the Island nation’s ninth Presidential election By www.thehindu.com Published On :: Mon, 23 Sep 2024 00:10:00 +0530 The spirit of the mandate of the presidential poll was clear — for change Full Article Editorial
lec Kashmir conflict: On the J&K elections By www.thehindu.com Published On :: Thu, 26 Sep 2024 00:20:00 +0530 The political divide between national parties and regional parties is clear Full Article Editorial
lec Heartland murmurs: On the Haryana Assembly elections By www.thehindu.com Published On :: Wed, 02 Oct 2024 00:20:00 +0530 Haryana may throw up surprises after the realignments Full Article Editorial
lec Healthy sign: On the voting in the 2024 J&K Assembly elections By www.thehindu.com Published On :: Thu, 03 Oct 2024 00:10:00 +0530 Turnout numbers in the Assembly elections show distinct patterns in south Kashmir Full Article Editorial
lec Inflection point: On the escalation in the multi-party West Asia conflict By www.thehindu.com Published On :: Thu, 03 Oct 2024 00:20:00 +0530 West Asia needs the intervention of major world powers for peace Full Article Editorial
lec Flipping scripts: On the Haryana and J&K election results By www.thehindu.com Published On :: Wed, 09 Oct 2024 00:20:00 +0530 BJP and INDIA bloc emerge clear winners in Haryana and Jammu & Kashmir Full Article Editorial
lec Against the odds: On the 2024 Haryana Assembly elections By www.thehindu.com Published On :: Thu, 10 Oct 2024 00:20:00 +0530 The Congress could not counter the caste polarisation in Haryana Full Article Editorial
lec Respect the mandate: On the 2024 Jammu and Kashmir elections By www.thehindu.com Published On :: Fri, 11 Oct 2024 00:20:00 +0530 With elections done and dusted, J&K now must return to statehood Full Article Editorial
lec Battle of wits: On the Maharashtra and Jharkhand elections By www.thehindu.com Published On :: Fri, 18 Oct 2024 00:20:00 +0530 The Maharashtra and Jharkhand polls will witness intense political battles Full Article Editorial
lec Neck and neck: On the U.S. presidential election By www.thehindu.com Published On :: Sat, 26 Oct 2024 00:10:00 +0530 Trump and Harris offer U.S. voters vastly different choices Full Article Editorial
lec Tough task: On the battle lines in the Jharkhand Assembly election By www.thehindu.com Published On :: Wed, 30 Oct 2024 00:20:00 +0530 Coalitional incoherence could stymie the INDIA bloc’s effort to retain power in Jharkhand Full Article Editorial
lec Design, synthesis, inhibitory activity, and molecular simulations study for D-glucose-conjugated thioureas containing pyrimidine ring as multitarget inhibitors against α-amylase, α-glucosidase, DDP-4, and PTP1B in Type 2 diabetes mellitus By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3395-3417DOI: 10.1039/D4MD00334A, Research ArticleVu Ngoc Toan, Do Son Hai, Hoang Thi Kim Van, Nguyen Minh Tri, Duong Ngoc Toan, Nguyen Thi Thanh Mai, Nguyen Dinh ThanhD-Glucose-conjugated thioureas from 2-aminopyrimidines had inhibitory activity against α-amylase, α-glucosidase, DPP-4, PTP1B. The cytotoxicity, inhibitory kinetics, and molecular simulations of the most potent inhibitors 8k, 8j, 8f, and 8h were studied.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
lec Lead optimisation of OXS007417: in vivo PK profile and hERG liability modulation to optimise a small molecule differentiation agent for the potential treatment of acute myeloid leukaemia By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3495-3506DOI: 10.1039/D4MD00275J, Research Article Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Thomas J. Cogswell, Laia Josa-Culleré, David Zimmer, Sébastien R. G. Galan, Morgan Jay-Smith, Kate S. Harris, Carole J. R. Bataille, Thomas R. Jackson, Douzi Zhang, Stephen G. Davies, Paresh Vyas, Thomas A. Milne, Graham M. Wynne, Angela J. RussellThe optimisation of a class of AML differentiation agents is described to show improved potency, solubility and stability, reduced off target toxicity, and tumour regression in a murine model in vivo.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
lec Pyridazinone-based derivatives as anticancer agents endowed with anti-microbial activity: molecular design, synthesis, and biological investigation By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3529-3557DOI: 10.1039/D4MD00481G, Research ArticleMohamed K. S. El-Nagar, Mai I. Shahin, Mohammed F. El-Behairy, Ehab S. Taher, Mohamed F. El-Badawy, Marwa Sharaky, Dalal A. Abou El Ella, Khaled A. M. Abouzid, Mai AdelDiscovery of novel pyridazinone derivatives with dual antimicrobial and anticancer activities.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
lec Design, synthesis and biological evaluation of a novel PSMA–PI3K small molecule drug conjugate By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3485-3494DOI: 10.1039/D4MD00246F, Research ArticleShouguo Peng, Haixia Li, Weilu Cui, Tianning Xiong, Jiaqi Hu, Haixiang Qi, Songwen Lin, Deyu Wu, Ming Ji, Heng XuA novel PSMA–PI3K small molecule drug conjugate has been prepared, highlighting its potential in targeted cancer therapy.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
lec Sidechain structure–activity relationships of cyclobutane-based small molecule αvβ3 antagonists By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3616-3624DOI: 10.1039/D4MD00306C, Research Article Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Adam Throup, Manar Saleh Zraikat, Andrew Gordon, Shohreh Jafarinejad Soumehsaraei, Kathrin D. Haase, Laurence H. Patterson, Patricia A. Cooper, Katherine Hanlon, Paul M. Loadman, Mark Sutherland, Steven D. Shnyder, Helen M. SheldrakeCyclobutanes provide a versatile scaffold for the synthesis of small molecule integrin antagonists with good metabolic stability and in vivo tolerability.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
lec Introduction to the themed collection on ‘AI in Medicinal Chemistry’ By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3284-3285DOI: 10.1039/D4MD90035A, EditorialJian Zhang, Ola Engkvist, Gerhard HesslerJian Zhang, Ola Engkvist and Gerhard Hessler introduce the RSC Medicinal Chemistry themed collection on ‘AI in Medicinal Chemistry’.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
lec Therapeutic upregulation of DNA repair pathways: strategies and small molecule activators By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00673A, Review ArticleJuhyung Song, Cheoljun Park, Francis E. B. Cabanting, Yong Woong JunPotential therapeutic target proteins for upregulating DNA repair system are reviewed, along with reported small-molecule activators.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
lec Introduction to the themed collection in honour of Professor Christian Leumann By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD90039A, EditorialMarcel Hollenstein, Eugen StulzMarcel Hollenstein and Eugen Stulz introduce the cross-journal themed collection celebrating Christian Leumann’s retirement.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
lec Development, biological evaluation, and molecular modelling of some benzene-sulfonamide derivatives as protein tyrosine phosphatase-1B inhibitors for managing diabetes mellitus and associated metabolic disorders By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00594E, Research ArticleNagat Ghareb, Khaled M. Darwish, Mohamed S. Nafie, Ranwa Elrayess, Noha M. Abourobe, Shaimaa A. Fattah, Reem M. Hazem, Eman T. Mehanna, Ranza ElrayessOne benzene-sulfonamide derivative exhibited potent protein tyrosine phosphatase-1B inhibition for managing diabetes mellitus and associated metabolic disorders.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
lec Novel benzenesulfonamides containing a dual triazole moiety with selective carbonic anhydrase inhibition and anticancer activity By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00617H, Research ArticleAida Buza, Cüneyt Türkeş, Mustafa Arslan, Yeliz Demir, Busra Dincer, Arleta Rifati Nixha, Şükrü BeydemirIn this research, a series of sulfonamides incorporating a 1,2,3-triazolyloxime substituted 1,2,3-triazolyl moiety was conceptualized, synthesized, and investigated as carbonic anhydrase inhibitors.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
lec S-MGBs bearing amidine tail groups are potent, selective antiplasmodial agents By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00619D, Research Article Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Marina Perieteanu, Tayner Rodriguez Garzon, Leah M. C. McGee, Abedawn I. Khalaf, Colin J. Suckling, Rebecca Beveridge, Vicky M. Avery, Fraser J. Scott25 S-MGBs, including those bearing an amidine tail group, were investigated for their antiplasmodial, in vitro activity against 3D7 and Dd2 strains of P. falciparum. Several potent, and selective, hit compounds were identified.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
lec Synthesis of cationic N-acylated thiazolidine for selective activity against Gram-positive bacteria and evaluation of N-acylation's role in membrane-disrupting activity By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00626G, Research ArticleAleena Pious, Vignesh Venkatasubramanian, Dharshini Karnan Singaravelu, Subburethinam Ramesh, Fuad Ameen, Anbazhagan VeerappanLipidation modulates the Gram-selective antibacterial activity of QPyNATh.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
lec EPS’s dream of AIADMK staging a comeback in 2026 election will not materialise: Law Minister Regupathy By www.thehindu.com Published On :: Fri, 08 Nov 2024 20:25:59 +0530 Full Article Tiruchirapalli
lec Ferrari's Leclerc fined for swearing By www.rediff.com Published On :: Stewards at the Brazilian race summoned Leclerc on Friday, acting on a report from the governing FIA's media delegate and after reviewing a written transcript. Full Article
lec Economic results in a year of elections By www.thehindubusinessline.com Published On :: Sun, 10 Nov 2024 20:31:09 +0530 Nearly half the world voted this year to choose governments and fiscal roadmaps Full Article Current Account
lec Delhi election: AAP to hold nine-day convention for party workers By www.thehindu.com Published On :: Thu, 07 Nov 2024 01:05:04 +0530 Full Article Delhi
lec Three arrested for raping intellectually disabled research scholar from Odisha By www.thehindu.com Published On :: Fri, 08 Nov 2024 01:09:38 +0530 Full Article Delhi
lec Delhi Assembly elections | Congress leader Mateen Ahmed joins AAP, AAP leader Harsharan Singh Balli returns to BJP By www.thehindu.com Published On :: Mon, 11 Nov 2024 01:32:23 +0530 Setback for Congress as five-time MLA Mateen Ahmed jumps ship to Aam Aadmi Party, days after his son, daughter-in-law join Kejriwal-led party; former Minister Balli quits AAP and returns to BJP Full Article Delhi
lec Dialectics of government deficits By www.thehindubusinessline.com Published On :: Sun, 03 Jan 2021 20:03:22 +0530 The book, espousing modern monetary theory, busts a few conservative myths on government spending Full Article Books
lec Farm loan waivers and elections: How do they affect farmers and governments? By www.thehindu.com Published On :: Mon, 27 May 2024 22:42:42 +0530 Promises to waive off farm loans have been issued by most political parties during this Lok Sabha election. Here’s a look at how these waivers are implemented, the effect on farmers and governments and what alternatives exist Full Article Lok Sabha Elections
lec Over ₹13 crore funds needed to support farmers in drought-affected areas of Nellore, says Collector By www.thehindu.com Published On :: Wed, 19 Jun 2024 20:07:59 +0530 Ten in the district have been declared as ‘drought mandals’ by the NDMA; over 50% of crop was lost in Sitaramapuram while 30-40% of crops were lost in the remaining nine mandals Full Article Andhra Pradesh
lec Anantapur Collector urges farmers to adopt natural practices By www.thehindu.com Published On :: Wed, 18 Sep 2024 20:34:15 +0530 V. Vinod Kumar visits several watershed structures in the district implemented by Accion Fraterna Ecology Centre with funding from NABARD Full Article Andhra Pradesh
lec Collective memory as currency [electronic resource] : the dominance of the past in the present / Tracy Adams. By darius.uleth.ca Published On :: Berlin ; Boston : De Gruyter [2024] Full Article
lec The certainty trap [electronic resource] : why we need to question ourselves more--and how we can judge others less / Ilana Redstone ; foreword by Joe Walsh. By darius.uleth.ca Published On :: Durham, North Carolina : Pitchstone Publishing, [2024] Full Article
lec Observability and mathematics [electronic resource] : Quantum Yang-Mills theory and modelling / Boris Khots. By darius.uleth.ca Published On :: Full Article
lec U.S. Stock market: Wall Street rallies on Election Day as economy remains solid By www.thehindu.com Published On :: Wed, 06 Nov 2024 08:04:30 +0530 U.S. stocks rally on election day, with S&P 500 and Dow Jones climbing, despite uncertainty over results Full Article U.S. Elections
lec Collector forwards complaint against teacher to Education Department By www.thehindu.com Published On :: Mon, 11 Nov 2024 18:26:31 +0530 Full Article Tiruchirapalli
lec Nanoconfinement effects on the dynamics of an ionic liquid-based electrolyte probed by multinuclear NMR By pubs.rsc.org Published On :: Soft Matter, 2024, 20,8436-8445DOI: 10.1039/D4SM01058B, Paper Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Andrei Filippov, Maiia Rudakova, Victor P. Archipov, Faiz Ullah ShahDiffusivity is controlled by exchange of ions between “narrow” and “large” pores that results in an abnormal temperature variation. Li+ ions are solvated inside the porous glasses and their diffusivity remains slower as compared to the organic ions.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
lec Development of a coarse-grained molecular dynamics model for poly(dimethyl-co-diphenyl)siloxane By pubs.rsc.org Published On :: Soft Matter, 2024, 20,8480-8492DOI: 10.1039/D4SM00875H, PaperWeikang Xian, Amitesh Maiti, Andrew P. Saab, Ying LiPolydimethylsiloxane and its copolymer systems have a wide range of application. We systematically develop a coarse-grained MD model for PDMS-co-PDPS system. The model preserves the structural and dynamic properties of the material quantitatively.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
lec Segregative phase separation of strong polyelectrolyte complexes at high salt and high polymer concentrations By pubs.rsc.org Published On :: Soft Matter, 2024, 20,8505-8514DOI: 10.1039/D4SM00994K, Paper Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Conner H. Chee, Rotem Benharush, Lexi R. Knight, Jennifer E. LaaserComplexes of strong polyelectrolytes prepared well above the binodal are shown to undergo hydrophobicity-driven segregative phase separation.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
