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3 more Delhi pvt hosps to treat corona patients

3 more Delhi pvt hosps to treat corona patients




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Delhi lockdown: Today's updates from your city

Delhi lockdown: Today's updates from your city




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Confusion over Delhi's Covid-19 toll as govt data, figures from hospitals don't match | Delhi News - Times of India

Confusion over Delhi's Covid-19 toll as govt data, figures from hospitals don't match | Delhi News - Times of India




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Bombay high court: State must decide on migrants’ travel cost

Bombay high court: State must decide on migrants’ travel cost




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Maharashtra education department tells schools to roll back fee hike

Maharashtra education department tells schools to roll back fee hike




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Maharashtra council polls: NCP may field Shashikant Shinde, Amol Mitkari | Mumbai News - Times of India

Maharashtra council polls: NCP may field Shashikant Shinde, Amol Mitkari | Mumbai News - Times of India




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China conducts 1st Covid vaccine test on monkeys

China conducts 1st Covid vaccine test on monkeys





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PE/VC investments hit 24-month low of $1.7 bn, value falls by 39%

Uncertainty over the impact of Covid-19 is expected to act as a significant headwind to Indian PE/VC investments




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Coronavirus impact: Early funding of start-ups may hit a stumbling block

This comes as seed investments in India during the January-March quarter, which was hit by the lowest level in five quarters




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[ASAP] PTP1B-Inhibiting Branched-Chain Fatty Acid Dimers from <italic toggle="yes">Eremophila oppositifolia</italic> subsp. <italic toggle="yes">angustifolia</italic> Identified by High-Resolution PTP1B Inhibiti

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00070




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[ASAP] Spongian Diterpenoids Derived from the Antarctic Sponge <italic toggle="yes">Dendrilla antarctica</italic> Are Potent Inhibitors of the <italic toggle="yes">Leishmania</italic> Parasite

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00025




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[ASAP] Naphthacemycins from a <italic toggle="yes">Streptomyces</italic> sp. as Protein-Tyrosine Phosphatase Inhibitors

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b00417




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[ASAP] Synthesis of the 1,2,4-Thiadiazole Alkaloid Polyaurine B

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00166




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[ASAP] Diisonitrile-Mediated Reactive Oxygen Species Accumulation Leads to Bacterial Growth Inhibition

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00125




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[ASAP] Aromatic Esters of the Crinane Amaryllidaceae Alkaloid Ambelline as Selective Inhibitors of Butyrylcholinesterase

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b00561




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[ASAP] Talarolactone A, an Isocoumarin Derivative Fused with Dihydrothiophene with Selective Antimigratory Activity from the Endolichenic Fungus <italic toggle="yes">Talaromyces</italic> sp.

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00024




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[ASAP] Phenylpropanoid-Conjugated Triterpenoids from the Leaves of <italic toggle="yes">Actinidia arguta</italic> and Their Inhibitory Activity on a-Glucosidase

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b00643




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[ASAP] Cyperane-Type and Related (Nor)Sesquiterpenoids from the Root Bark of <italic toggle="yes">Acanthopanax gracilistylus</italic> and Their Inhibitory Effects on Nitric Oxide Production

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b00913




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[ASAP] Phaeosphaones: Tyrosinase Inhibitory Thiodiketopiperazines from an Endophytic <italic toggle="yes">Phaeosphaeria fuckelii</italic>

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00046




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[ASAP] Cytotoxic Monoterpenoid Indole Alkaloids from <italic toggle="yes">Tabernaemontana corymbosa</italic> as Potent Autophagy Inhibitors by the Attenuation of Lysosomal Acidification

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b00856




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[ASAP] Review of Progress in the Chemistry of Organic Natural Products<source>Progress in the Chemistry of Organic Natural Products</source>, Volume 108. Edited by A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Jun’ichi Kobayashi, Yoshinori A

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00356




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[ASAP] Structural Specificity of Flavonoids in the Inhibition of Human Fructose 1,6-Bisphosphatase

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00014




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[ASAP] Inhibitory Effect of Cannabidiol on the Activation of NLRP3 Inflammasome Is Associated with Its Modulation of the P2X7 Receptor in Human Monocytes

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00138




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[ASAP] Advances in the Biosynthesis of Pyranocoumarins: Isolation and <sup>13</sup>C-Incorporation Analysis by High-Performance Liquid Chromatography–Ultraviolet–Solid-Phase Extraction–Nuclear Magnetic Resonance Data

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b00607




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Highlight.js 10, Node 14, and modern React in 20 minutes

#485 — April 24, 2020

Unsubscribe  :  Read on the Web

JavaScript Weekly

Introducing Crank.js: A New JSX-Driven Framework — A new framework for creating JSX-driven components with functions, promises and generators. If you haven’t got time to read the creator’s lengthy (but well worth reading!) rationale for creating another framework, check out the GitHub repo or jump straight into a CodeSandbox example. I hope to see a lot more about this in the near future.

Brian Kim

The Cost of JavaScript Frameworks — Using data from the HTTP Archive, Tim explores the performance cost of using various popular frameworks as a starting point. Some good analysis here.

Tim Kadlec

You Hacked the Gibson? Yeah, They Built Their Own Login — Don't let Crash Override pwn your app. FusionAuth adds secure login, registration and user management to your app in minutes not months. Download our community edition for free.

FusionAuth sponsor

Node.js 14 Released — v14 now becomes the current ‘release’ line with it becoming a LTS (Long Term Support) release in October. Diagnostic reports are now a stable feature, it now uses V8 8.1, there's an experimental Async Local Storage API, and more.

Michael Dawson and Bethany Griggs

Vidact: A Compiler to Convert React-like Apps to Vanilla JS — Compiles pure React-compatible JavaScript (JSX) to vanilla JavaScript with no virtual DOM.. think similar to Svelte, but without introducing a new syntax. A curious idea.

Mohamad Mohebifar

Highlight.js 10.0: The Web Syntax Highlighter Library — I always laugh when I see a big release of a popular library and saw we last linked it 5 years ago ???? Nonetheless, this is a big release and Highlight.js continues to be a fantastic library for syntax highlighting code.

highlight.js

???? Jobs

Senior Full-stack Developer (Malmö/Sweden) — Every day is different from the next. Join our upbeat Team and work on exciting, major projects using a modern JavaScript stack.

Ortelius AB

Find a Job Through Vettery — Vettery specializes in tech roles and is completely free for job seekers. Create a profile to get started.

Vettery

???? Tutorials

▶  React: The Basics in 20 Minutes — A well presented, up to date (yep, it covers hooks) tutorial that doesn’t hang around, whether you’re new to React or just want a refresher.

Devistry

Creating Web Apps via TypeScript and webpack — The example app doesn’t use any front-end framework, just vanilla DOM APIs. Some knowledge of TypeScript, webpack, and npm are required, but this is a neat way to bring together a bunch of tools.

Axel Rauschmayer

What Is The toJSON() Function? — If an object has a toJSON function, JSON.stringify() calls toJSON() and serializes the return value from toJSON() instead.

Valeri Karpov

A Much Faster Way to Debug Code Than with Breakpoints or console.log — Move forward and backwards through your code to understand what led to a specific bug, view runtime values, edit-and-continue, and more.

Wallaby.js sponsor

How Does TypeScript Work? A Bird’s Eye View — Dr. Axel goes into depth on the structure of a typical TypeScript project, what gets compiled, and how can an IDE be used to write TypeScript. Aimed at people who haven’t yet picked TypeScript up.

Axel Rauschmayer

10 Lesser Known Angular Features You've Probably Never Used

W3Radar

You Might Not Need switch — Using an object of outcomes instead of switch suits many use cases, though take care over readability.

Valentino Gagliardi

???? Upcoming Online Events

  • Pick JS (May 8) — Aimed at intermediate to expert JS developers rather than beginners.
  • JavaScript Remote Conf 2020 (May 14-15) — Speakers lined up already include Douglas Crockford, Aimee Knight and Christian Heilmann.
  • ESNEXT CONF 2020 (May 18-22) — From the Pika folks (of Snowpack fame). 12 speakers over 5 days so it's a gradual pace.
  • ForwardJS (May 26-29) — A real world event (ForwardJS Ottawa) that has now become a virtual event.
  • CascadiaJS 2020 (September 1-2) — This upcoming online conference is set to take place in September, and the CFP is open now through May 15.

???? Code & Tools

Phelia: A Reactive Slack Application Framework — If you think Slack apps were all about text bots, think again.. you can now create apps complete with in-app UIs. Phelia brings the React approach to the task.

Max Chehab

Marked.js 1.0: A Fast Markdown Parser and Compiler — Got Markdown to render? Marked.js to the rescue. While the project is years old, 1.0 has dropped just this week. Here’s a live demo.

Christopher Jeffrey

Stream Chat API & JavaScript SDK for Custom Chat Apps — Build real-time chat in less time. Rapidly ship in-app messaging with our highly reliable chat infrastructure.

Stream sponsor

Alpine.js: A Minimal Framework for Composing JS Behavior in Your Markup — We only gave Alpine a brief link when it first dropped but with new versions coming out thick and fast, we think it’s well worth a look. Billed as “like Tailwind for JavaScript”, Alpine lets you keep the HTML you know and love and just pepper it with JavaScript as and where appropriate.

Alpine.js

enroute: A React Router with a Small Footprint for Modern Browsers

TJ Holowaychuk

Rosetta: A General Purpose Internationalization Library in 292 Bytes — Less than 300 bytes, but does have a few dependencies. Aims to be very simple and is targeted at basic string use cases.

Luke Edwards

NAB 2020 May Be Canceled, But The Full Bitmovin Experience Is Not

Bitmovin Inc. sponsor

Hotkey 1.4: Trigger an Action on an Element When a 'Hotkey' is Pressed — Use Hotkey, set the data-hotkey attribute on your elements, and you get keyboard shortcuts. GitHub built and uses it (look for the data-hotkey attributes on their pages).

GitHub

web-worker: Consistent Web Workers for the Browser and Node — In Node it works as a web-compatible Worker implementation atop worker_threads. In the browser it’s an alias for Worker.

Jason Miller




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A big positive in this Budget is tax exemptions: PGIM India Mutual Fund CEO

Abolishing DDT will attract investments, said Ajit Menon, CEO of PGIM India Mutual Fund




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ITC is first to hike cigarette prices post budget; makes them 10-20% dearer

Price increase brought on by spike in National Calamity Contingency Duty announced in Budget




hi

How to Enroll Participants in Research Ethically

Interview with David Wendler, PhD, author of How to Enroll Participants in Research Ethically




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Sleep-Disordered Breathing, Hypoxia, and Risk of Mild Cognitive Impairment and Dementia in Older Women

Interview with Katie L. Stone, PhD, author of Sleep-Disordered Breathing, Hypoxia, and Risk of Mild Cognitive Impairment and Dementia in Older Women




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Identification of Chronic Obstructive Pulmonary Disease in Lung Cancer Screening Computed Tomographic Scans

Interview with Pim A. de Jong, MD, PhD, author of Identification of Chronic Obstructive Pulmonary Disease in Lung Cancer Screening Computed Tomographic Scans




hi

Neuron Number and Size in Prefrontal Cortex of Children With Autism

Interview with Eric Courchesne, PhD, author of Neuron Number and Size in Prefrontal Cortex of Children With Autism




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Effects of the CETP Inhibitor Evacetrapib Administered as Monotherapy or in Combination With Statins on HDL and LDL Cholesterol: A Randomized Controlled Trial

Interview with Steven E. Nissen, MD, author of Effects of the CETP Inhibitor Evacetrapib Administered as Monotherapy or in Combination With Statins on HDL and LDL Cholesterol: A Randomized Controlled Trial




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Universal Screening and Drug Treatment of Dyslipidemia in Children and Adolescents

Interview with Frederick P. Rivara, MD, MPH, author of Universal Screening and Drug Treatment of Dyslipidemia in Children and Adolescents




hi

Lansoprazole for Children With Poorly Controlled Asthma: A Randomized Controlled Trial

Interview with Janet T. Holbrook, MPH, PhD, author of Lansoprazole for Children With Poorly Controlled Asthma: A Randomized Controlled Trial




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Moderate to Vigorous Physical Activity and Sedentary Time and Cardiometabolic Risk Factors in Children and Adolescents

Interview with Ulf Ekelund, PhD, author of Moderate to Vigorous Physical Activity and Sedentary Time and Cardiometabolic Risk Factors in Children and Adolescents




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Amoxicillin for Acute Rhinosinusitis: A Randomized Controlled Trial

Interview with Jay F. Piccirillo, MD, author of Amoxicillin for Acute Rhinosinusitis: A Randomized Controlled Trial




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Association of Mental Health Disorders With Prescription Opioids and High-Risk Opioid Use in US Veterans of Iraq and Afghanistan

Interview with Karen H. Seal, MD, MPH, author of Association of Mental Health Disorders With Prescription Opioids and High-Risk Opioid Use in US Veterans of Iraq and Afghanistan




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Out-of-Pocket Medication Costs and Use of Medications and Health Care Services Among Children With Asthma

Interview with Dana P. Goldman, PhD, author of Out-of-Pocket Medication Costs and Use of Medications and Health Care Services Among Children With Asthma




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Primary Health Care in Low-Income Countries: Building on Recent Achievements

Interview with Jeffrey D. Sachs, PhD, author of Primary Health Care in Low-Income Countries: Building on Recent Achievements




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HIV Development Assistance and Adult Mortality in Africa

Interview with Eran Bendavid, MD, MS, author of HIV Development Assistance and Adult Mortality in Africa




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Marshaling Leadership for High-Value Health Care

Interview with Gary S. Kaplan, MD, author of Marshaling Leadership for High-Value Health Care




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HIV in Persons Born Outside the United States, 2007-2010

Interview with Adria Tassy Prosser, PhD, author of HIV in Persons Born Outside the United States, 2007-2010




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Association of Childhood Pertussis With Receipt of 5 Doses of Pertussis Vaccine by Time Since Last Vaccine Dose, California, 2010

Interview with Lara K. Misegades, PhD, MS, author of Association of Childhood Pertussis With Receipt of 5 Doses of Pertussis Vaccine by Time Since Last Vaccine Dose, California, 2010




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Association Between Maternal Use of Folic Acid Supplements and Risk of Autism Spectrum Disorders in Children

Interview with Pål Surén, author of Association Between Maternal Use of Folic Acid Supplements and Risk of Autism Spectrum Disorders in Children




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Relationship Between Occurrence of Surgical Complications and Hospital Finances, and Uwe E. Reinhardt, PhD, author of Making Surgical Complications Pay

Interview with Atul A. Gawande, MD, MPH, author of Relationship Between Occurrence of Surgical Complications and Hospital Finances, and Uwe E. Reinhardt, PhD, author of Making Surgical Complications Pay




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Relationship Between Occurrence of Surgical Complications and Hospital Finances, and Uwe E. Reinhardt, PhD, author of Making Surgical Complications Pay

Interview with Atul A. Gawande, MD, MPH, author of Relationship Between Occurrence of Surgical Complications and Hospital Finances, and Uwe E. Reinhardt, PhD, author of Making Surgical Complications Pay




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Prevalence of a Healthy Lifestyle Among Individuals With Cardiovascular Disease in High-, Middle- and Low-Income Countries: The Prospective Urban Rural Epidemiology (PURE) Studyterview

Interview with Koon Teo, MB, PhD, author of Prevalence of a Healthy Lifestyle Among Individuals With Cardiovascular Disease in High-, Middle- and Low-Income Countries: The Prospective Urban Rural Epidemiology (PURE) Study




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Prenatal Valproate Exposure and Risk of Autism Spectrum Disorders and Childhood Autism

Interview with Jakob Christensen, PhD, author of Prenatal Valproate Exposure and Risk of Autism Spectrum Disorders and Childhood Autism




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Lutein + Zeaxanthin and Omega-3 Fatty Acids for Age-Related Macular Degeneration: The Age-Related Eye Disease Study 2 (AREDS2) Randomized Clinical Trial

Interview with Emily Y. Chew, MD, author of Lutein + Zeaxanthin and Omega-3 Fatty Acids for Age-Related Macular Degeneration: The Age-Related Eye Disease Study 2 (AREDS2) Randomized Clinical Trial