A new report from the National Academies of Sciences, Engineering, and Medicine highlights the dynamic process of learning throughout the life span and identifies frontiers in which more research is needed to pursue an even deeper understanding of human learning.

The current measles outbreaks in the United States and elsewhere are being fueled by misinformation about the safety of vaccines.

The Gulf Research Program (GRP) of the National Academies of Sciences, Engineering, and Medicine today announced a new funding opportunity under its Healthy Ecosystems Initiative.

A new report from the National Academies of Sciences, Engineering, and Medicine examines the effects and efficacy of using dispersants in marine oil spill response.

The National Academies of Sciences, Engineering, and Medicine have joined with over 40 colleges, universities, and research institutions to launch an Action Collaborative on Preventing Sexual Harassment in Higher Education.

The changes in brain structure and connectivity that occur between the ages of 10 and 25 present adolescents with unique opportunities for positive, life-shaping development, and for recovering from past adversity, says a new report from the National Academies of Sciences, Engineering, and Medicine.

The U.S. National Academy of Sciences and U.S. National Academy of Medicine joined the science academies of South Africa, Brazil, and Germany today in issuing a statement calling for urgent worldwide action to reduce air pollution.

A new report from the National Academies of Sciences, Engineering, and Medicine – which reviews a separate report by a federally funded laboratory that examines options for treating low-activity radioactive waste at the Hanford Nuclear Reservation -- is available for public comment until Oct. 31.

We tend to think of the process of seeing as fairly objective — that our eyes are similar to cameras, neutrally taking in light and turning it into pictures. But research has shown that biases buried beneath our awareness can powerfully shape how we see.

U.S. colleges and universities should take a more intentional, inclusive, and evidence-based approach to mentoring students in STEMM (science, technology, engineering, mathematics, and medicine) – a shift that could engage and help retain a broader group of students in these fields, says a new report from the National Academies of Sciences, Engineering, and Medicine.

A new report from the National Academies of Sciences, Engineering, and Medicine urges systemic action to change the culture in STEMM (science, technology, engineering, mathematics, and medicine) to address the underrepresentation of women in these fields.

The 1.3 million nursing home residents in the U.S. make up less than 0.5 percent of the nation’s population, but represent approximately 15 percent of COVID-19 related deaths to date.

India-based merchant payment and lending service provider BharatPe has announced disbursing funds...

US-based payments processor Nets has released

Perk Labs has formally launched new verticals and unveiled the...

The Trump administration asked the Supreme Court to block Congress from seeking the materials, saying, "The government will suffer irreparable harm absent a stay."; Credit: Andrew Harnik/AP

The Supreme Court has temporarily put on hold the release of redacted grand jury material from the Russia investigation to a House panel.

The Trump administration is trying to block the release.

Last October, a district court judge ruled the Justice Department had to turn over the materials, which were blacked out, from former special counsel Robert Mueller's report into Russian interference in the 2016 election.

An appeals court upheld the decision, but the Trump administration, hoping to keep the evidence secret, appealed to the Supreme Court.

Chief Justice John Roberts' order temporarily stops the process. Lawyers for the House Judiciary Committee have until May 18 to file their response to the Justice Department's attempts to keep the materials from the House panel.

The Justice Department had until Monday to turn over the material following the appeals court order. But on Thursday, the Trump administration asked the Supreme Court to block Congress from seeking it, saying, "The government will suffer irreparable harm absent a stay."

This content is from Southern California Public Radio. View the original story at SCPR.org.

Brian Dennehy, known for his interpretations of characters created by Eugene O'Neill and Arthur Miller, has died at the age of 81.; Credit: Mike Piscitelli /Dennehy Family

Brian Dennehy could go from viciously intimidating on film to weak and weary on stage. The actor died yesterday of cardiac arrest. His family says his death was not related to COVID-19. He was 81 years old.

Dennehy had a vast and varied body of work. On screen he was known for his roles in First Blood, Cocoon, and Tommy Boy. In theater, he earned wide acclaim for his depiction of the beleagured Willy Loman in the 1999 Broadway revival of Arthur Miller's Death of a Salesman. That performance earned him one of his two Best Actor Tony Awards. He earned the other in 2003 for his portrayal of family patriarch James Tyrone in Eugene O'Neill's Long Days Journey into Night.

Brian Manion Dennehy was born in Bridgeport, Connecticut, on July 9, 1938, and grew up on Long Island, New York. He was tall and broad-chested and played football in high school, but was also in love with theater. As an Irish Catholic, he didn't see much of a future for himself in acting until he saw Marlon Brando in On the Waterfront. "For the first time when I saw that picture, I realized there were people in the business who looked like me, and who sounded like me. And who came from places I came from" he said in an interview with WHYY's Fresh Air in 1999. "Before that time, acting was like ballet — something I could appreciate but never consider myself a part of."

On stage, Dennehy was a revered actor, particularly in the Chicago theater scene. His two Tony-award winning performances began at the famed Goodman Theatre, where he also performed in Samuel Beckett's Krapp's Last Tape. On Broadway, his credits include Translations, Love Letters, and Inherit the Wind.

Earlier in his career, Dennehy wasn't picky about his roles — and he wasn't shy about it either. "I had kids," he said in the Fresh Air interview. "I had kids who were ready to go to college, and I knew I had the responsibility — which I did not resent — to make sure they had good educations." Dennhey said his wide range of roles on television, where he acted in everything from Dynasty to M*A*S*H to Just Shoot Me, helped him become a more efficient actor. Dennehy worked all throughout his life, most recently appearing in the television series The Blacklist, as well the upcoming independent film Driveways.

This content is from Southern California Public Radio. View the original story at SCPR.org.

The status of soil can be represented by many properties. However, how well they represent soil status depends on the level of rainfall in the area. Researchers in Spain found that in wet regions soil status is strongly linked to biological factors, such as vegetation cover and biodiversity. In drier regions, status has a stronger link to the physical properties of the soil.

An inmate firefighter from Oak Glen Conservation Camp near Yucaipa, California sets a backfire during the Easy Fire on October 30, 2019 near Simi Valley, California. ; Credit: David McNew/Getty Images

Red flag warning: They're some of the most dreaded words in fire-prone California. By now, many locals understand the term to basically mean, "Watch out for fires. It's about to get real."

KPCC has been demystifying some of the jargon around fires, so when Betsy Lawlor from Diamond Bar asked us to break down exactly what a red flag warning is, we were more than happy to explain.

This content is from Southern California Public Radio. View the original story at SCPR.org.

An apartment in Pomona that leases through the Housing for Health Program. (Matt Tinoco/LAist)

Our California Dream collaboration is looking for solutions to some of California's most pressing problems, in this case, homelessness. An initiative in Los Angeles seeks to save taxpayer money by housing some of the most vulnerable residents — those who cycle from the street to the emergency room and back again.

The California Dream series is a statewide media collaboration of CALmatters, KPBS, KPCC, KQED and Capital Public Radio with support from the Corporation for Public Broadcasting and the James Irvine Foundation.

READ THE STORY AT LAist.com.

This content is from Southern California Public Radio. View the original story at SCPR.org.

A moment in Larry Mantle’s recent conversation with Steve Inskeep has stuck with me.

The NPR Morning Edition co-host was in our Pasadena studios to talk about his latest book, Imperfect Union. Asked how he approaches his day job, Inskeep told a story about the time he dispassionately called a heartbreaking loss for his high school football team. That “straight call” earned praise from a veteran broadcaster he admired. It’s a lesson, he said, that stayed with him.

“I may have a personal opinion; it doesn’t matter,” Inskeep told Mantle. “My job as a journalist is to get the facts right, that are in front of me, and you can do that even if you have a personal opinion.”

Mantle, who has hosted KPCC’s AirTalk for decades, responded: 

“You can’t do this work if you’re wired like an activist. I sort of see my wiring as more how a teacher would be, wired where you’re amassing information. You’re leading people through a story, and the joy is in people coming to their own conclusions.”

“If you’re an activist at all, you’re an activist for the truth,” Inskeep replied. 

Activists for truth. Finding joy in people reaching their own conclusions.

What a compelling description of what our newsroom strives to deliver every day to Southern Californians.

These were my thoughts even before my colleague at NPR came under attack for doing her job.

If you haven't been following the story, Secretary of State Mike Pompeo angrily objected to being questioned about Ukraine during an interview with All Things Considered co-host Mary Louise Kelly. Pompeo didn't care for Kelly's questions on air and the conversation grew even more contentious behind closed doors.

The next day he accused Kelly of lying about the topic of the interview and then reporting a conversation he claimed was off the record. [Including his odd demand she locate Ukraine on unmarked world map.]  Kelly has denied both claims and media outlets have reported on emails between her and Pompeo's staff that back up her assertion she told them the interview would go beyond questions about Iran.

Then, this week, the State Department denied credentials to NPR's Michele Kelemen, who'd been scheduled to cover Pompeo's trip to Europe.

NPR President and CEO John Lansing and Nancy Barnes, who heads news, are rightfully demanding answers.

Why does it matter? Because as Lansing notes having access to people in power is fundamental to "the role of journalism in America.

Get KPCC in your inbox

Breaking news alerts sent to your inbox

I want to take a few minutes to tell you more about how our newsroom works and why you’ll be hearing more from us about our mission and ambition.

Listeners may have noticed a new phrase on our air: “Democracy needs to be heard.” It’s a statement you’ll also start seeing on billboards and bus benches around Los Angeles.

It’s part of the first marketing campaign for our station in many years. The goal is to make more people aware of what we do and why we do it. We also want to grow our audience and our supporters, so we can do even more original journalism.

Southern California Public Radio — home to 89.3 KPCC, LAist Studios, and LAist.com — turns 20 this year. SCPR was born out of a belief that the region would embrace and support a news-focused NPR station serving Southern California with original programming and reporting.

In the two decades since, our members stepped up and helped us build what is now one of the biggest newsrooms in the region. We’ve gone from cramped quarters in the library of Pasadena City College, to a new headquarters in 2010, to today, when we have to scramble for desks for our growing operation.

If you’ve ever heard me on-air during a pledge drive, you’ve heard me talk about how remarkable it is that your support has fueled our ambition and growth. We’re the most listened to NPR station in Southern California. The public media model depends on people donating their hard-earned money because they believe in what we are doing. You don’t have to pay a dime to listen to us on your radio, or stream us on your smart speaker or our app. You’ll never hit a paywall when you visit our website.

Our relationship with you isn’t transactional — that’s one of the ways nonprofit member-supported newsrooms are different. Instead, we make a case that what we do matters, that it’s valuable to you — so valuable that you voluntarily support us (even though you can still listen and read if you don’t). 

That’s a powerful relationship.

It’s why we take community engagement so seriously. That means listening closely to your concerns, answering your questions, meeting you in person, thinking about how our coverage can be both for and about Southern Californians.

In September, we were awarded the first-ever Gather Award for engaged journalism from the Online News Association. In December, we won our second-in-a-row Champion of Curiosity Award for our breaking news coverage of the wildfires.

Our approach to engaged journalism has been transformational for coverage, and we’ve emerged as a clear leader in the industry — sharing what we’ve learned with other newsrooms.

***

We talk a lot about our public-service mission in this newsroom. It permeates how we approach stories. It’s why our reporters, producers, hosts and editors choose to work here. 

And we’ve made this promise to you:

“You deserve great local news — and we need your help to find those stories. We listen to what you’re curious about, what keeps you up at night, and who you want held accountable. We’re inviting you to be part of the conversation.”

We do this work because of you. We do it for you and with you. 

We’ve spent quite a bit of time thinking about how we’re finding and telling stories, and how we can do an even better job of delivering reporting that you won’t find anywhere else. We want our reporters to spend their energy on original stories (and not get stuck echoing information that everyone else is reporting). 

To that end, each reporter has their own individual mission statement to reflect their goals in covering communities and crucial issues. 

The free press is a cornerstone of democracy. That’s why in 1786 Thomas Jefferson wrote:

"Our liberty depends on the freedom of the press, and that cannot be limited without being lost." 

More than 200 years later, Nelson Mandela said: “A critical, independent and investigative press is the lifeblood of any democracy.”

Activists for truth. That means scrutinizing the information we receive from our sources or uncover through our reporting. It means giving you the context you need to consider what is fact and what is spin.

It’s truly an exciting time to work in our newsroom.

We have ambitious plans for coverage of the upcoming California primary and presidential election.

We have so much great work in progress — including three in-depth investigations scheduled to publish in the coming weeks.

Those stories took months to report, involving thousands of public documents, hundreds of miles of travel, and data analysis that no one else has done.

And it was only possible because of your support.  

Thank you.

Megan Garvey, Executive Editor

This content is from Southern California Public Radio. View the original story at SCPR.org.

Among those protesting stay-at-home orders this week at the California Capitol in Sacramento were activists who oppose governments requiring vaccinations for school children.; Credit: Katie Orr/KQED

Protests over stay-at-home orders because of COVID-19 have become more common around the country. In California, a surprising group is behind some of them: those who oppose mandatory vaccinations.

On Thursday, a mash-up of people mingled on the sidewalk in front of California's state Capitol in Sacramento. There were Trump supporters wearing MAGA hats and waving American flags. There were Christians, singing along to religious rock songs and raising their hands in prayer. The event's MC. urged Gov. Gavin Newsom to tune into their event.

"Everybody up at the Capitol, tell Gavin Newsom [to tune in to] 107.9 FM, if he wants to hear what we have to say," the MC told the crowd over loudspeakers. "It could be kind of good for him!"

There were also mothers with their children at the rally. Many people were not wearing face masks or observing social distancing protocols.

They'd all come out to protest California's stay-at-home order, put in place to slow the spread of COVID-19. This week's event was built around the National Day of Prayer, and featured pastors and sermons. But it was organized by a group called Freedom Angels, which was originally formed to fight mandatory vaccine laws in the state.

At the beginning of the rally, the group's founders took the stage, including Denise Aguilar.

"Hello everybody, my name is Denise, I'm one of the founders of Freedom Angels," Aguilar said to a cheering crowd. "Thank you guys for being out here to let Gov. Newsom know we're not going away! We've said this for years!"

The group has become a fixture at the Capitol ever since California passed a law requiring school students to be vaccinated and a second law tightening restrictions on medical exemptions for those vaccines. But another Freedom Angels founder, Stefanie Fetzer, said they're not a single-issue group. She said these events are about promoting personal freedom.

"I think what we're seeing now is the predictive modeling that they came out with in the beginning didn't hold true. We aren't seeing the numbers that they predicted," Fetzer said. "And instead of backing off of the shutdown and the restrictive measures that Gov. Newsom implemented, he seems to be doubling down."

Attention-seeking strategy

Public health advocates point out that the reason those early predictions didn't come true is that aggressive social distancing measures — including stay-at-home orders — worked. Democratic state Senator Richard Pan, who authored California's vaccine laws, believes this anti-vaccine group is aligning with others protesting the stay-at-home order as a way to promote their cause. After all, Pan said, a vaccine would eventually allow the economy to reopen.

"They have staged these protests to basically find a way to get media attention for themselves. They fund raise off of their activities as well," Pan said. "So, frankly, many of the anti-vaxxers who are involved in this are really there for their own interests."

It's common for anti-vaccine groups to latch onto other controversial issues, according to epidemiologist and vaccine educator René Najera. For instance, he points to abortion.

"They try to say that there are aborted fetal cells in vaccines — which there are not — to try to get the anti-abortion people on their side," he said. "And then they flip it around and say, also, 'My body, my choice.'"

Najera said those tactics can have dangerous outcomes, including making people think twice about getting vaccines. In fact, he said, in 2019 the World Health Organization named vaccine hesitancy, or people's reluctance to consider vaccination, as one of the world's top 10 public health challenges.

"And we saw the effects of that," Najera said. "We saw a rise of measles in the United States to the point where the elimination status of the United States for measles was in jeopardy."

Najera is confident vaccine opponents aren't going away. He says, if anything, the rise of social media has made it easier for them to spread their message. What he finds most frustrating is that these anti-vaccines protesters aren't just making choices that affect their own families. Najera says choosing not to vaccinate their children and joining other large protests to spread their message puts the health of everyone at risk.

This content is from Southern California Public Radio. View the original story at SCPR.org.

Chris Hemsworth and Rudhraksh Jaiswal in Extraction.; Credit: Netflix/Extraction (2020)

Larry Mantle and KPCC film critics Christy Lemire, Angie Han and Wade Major review this weekend’s new movie releases on streaming and VOD platforms.

• "Extraction" on Netflix

• "Bad Education" on HBO

• "Circus Of Books" on Netflix

• "Why Don't You Just Die!" on VOD (iTunes, Amazon & Google Play)

• "Beastie Boys Story" on Apple TV+

• "Robert The Bruce" on VOD (iTunes, Amazon, FandangoNOW & Google Play)

• "1BR" on VOD (iTunes) & DVD

• "The True History Of The Kelly Gang" on VOD (iTunes, Vudu & Google Play)

Guests:

Angie Han, KPCC film critic and deputy entertainment editor at Mashable; she tweets @ajhan

Christy Lemire, film critic for KPCC, RogerEbert.com and co-host of the ‘Breakfast All Day’ podcast; she tweets @christylemire

Wade Major, film critic for KPCC and CineGods.com

This content is from Southern California Public Radio. View the original story at SCPR.org.

A recent study has demonstrated that it is possible to identify which human pressures, such as fisheries and environmental pollution, are causing changes in Marine and Coastal by combining the trends in different indicators. This approach can be used as a tool for integrated ecosystem assessment and management.

Understanding the impacts of human activities on Marine and Coastal is important to ensure their sustainability. New research has indicated that seafloor ecosystems are less likely to recover from fishing if they are in rocky or reef habitats and if dredging and bottom trawling equipment is used for shellfish and various fish species. When fishing is combined with the extraction of aggregate for mineral resources, the impacts are even more damaging.

The effects of seafloor trawling can extend further than the immediate fishing grounds, affecting delicate deep-sea ecosystems, new research suggests. In this Mediterranean study, the researchers demonstrated that clouds of sediment from trawling reached deeper habitats, increasing water-borne sediment particle concentrations to a hundred times that of background levels.

Seabed fishing grounds in the UK are made up of intensively fished core areas surrounded by more rarely used marginal areas, new research shows. Excluding these margins, which contain only 10% of the total fishing activity, approximately halves the total area of fishing grounds. Thus reducing the fishing footprint by closing the marginal areas will disproportionately reduce the seabed impact of fishing activity.

'California Mountain Lions,' Episode 7: Human Interaction

The Trump administration asked the Supreme Court to block Congress from seeking the materials, saying, "The government will suffer irreparable harm absent a stay."; Credit: Andrew Harnik/AP

The Supreme Court has temporarily put on hold the release of redacted grand jury material from the Russia investigation to a House panel.

The Trump administration is trying to block the release.

Last October, a district court judge ruled the Justice Department had to turn over the materials, which were blacked out, from former special counsel Robert Mueller's report into Russian interference in the 2016 election.

An appeals court upheld the decision, but the Trump administration, hoping to keep the evidence secret, appealed to the Supreme Court.

Chief Justice John Roberts' order temporarily stops the process. Lawyers for the House Judiciary Committee have until May 18 to file their response to the Justice Department's attempts to keep the materials from the House panel.

The Justice Department had until Monday to turn over the material following the appeals court order. But on Thursday, the Trump administration asked the Supreme Court to block Congress from seeking it, saying, "The government will suffer irreparable harm absent a stay."

This content is from Southern California Public Radio. View the original story at SCPR.org.

Among those protesting stay-at-home orders this week at the California Capitol in Sacramento were activists who oppose governments requiring vaccinations for school children.; Credit: Katie Orr/KQED

Protests over stay-at-home orders because of COVID-19 have become more common around the country. In California, a surprising group is behind some of them: those who oppose mandatory vaccinations.

On Thursday, a mash-up of people mingled on the sidewalk in front of California's state Capitol in Sacramento. There were Trump supporters wearing MAGA hats and waving American flags. There were Christians, singing along to religious rock songs and raising their hands in prayer. The event's MC. urged Gov. Gavin Newsom to tune into their event.

"Everybody up at the Capitol, tell Gavin Newsom [to tune in to] 107.9 FM, if he wants to hear what we have to say," the MC told the crowd over loudspeakers. "It could be kind of good for him!"

There were also mothers with their children at the rally. Many people were not wearing face masks or observing social distancing protocols.

They'd all come out to protest California's stay-at-home order, put in place to slow the spread of COVID-19. This week's event was built around the National Day of Prayer, and featured pastors and sermons. But it was organized by a group called Freedom Angels, which was originally formed to fight mandatory vaccine laws in the state.

At the beginning of the rally, the group's founders took the stage, including Denise Aguilar.

"Hello everybody, my name is Denise, I'm one of the founders of Freedom Angels," Aguilar said to a cheering crowd. "Thank you guys for being out here to let Gov. Newsom know we're not going away! We've said this for years!"

The group has become a fixture at the Capitol ever since California passed a law requiring school students to be vaccinated and a second law tightening restrictions on medical exemptions for those vaccines. But another Freedom Angels founder, Stefanie Fetzer, said they're not a single-issue group. She said these events are about promoting personal freedom.

"I think what we're seeing now is the predictive modeling that they came out with in the beginning didn't hold true. We aren't seeing the numbers that they predicted," Fetzer said. "And instead of backing off of the shutdown and the restrictive measures that Gov. Newsom implemented, he seems to be doubling down."

Attention-seeking strategy

Public health advocates point out that the reason those early predictions didn't come true is that aggressive social distancing measures — including stay-at-home orders — worked. Democratic state Senator Richard Pan, who authored California's vaccine laws, believes this anti-vaccine group is aligning with others protesting the stay-at-home order as a way to promote their cause. After all, Pan said, a vaccine would eventually allow the economy to reopen.

"They have staged these protests to basically find a way to get media attention for themselves. They fund raise off of their activities as well," Pan said. "So, frankly, many of the anti-vaxxers who are involved in this are really there for their own interests."

It's common for anti-vaccine groups to latch onto other controversial issues, according to epidemiologist and vaccine educator René Najera. For instance, he points to abortion.

"They try to say that there are aborted fetal cells in vaccines — which there are not — to try to get the anti-abortion people on their side," he said. "And then they flip it around and say, also, 'My body, my choice.'"

Najera said those tactics can have dangerous outcomes, including making people think twice about getting vaccines. In fact, he said, in 2019 the World Health Organization named vaccine hesitancy, or people's reluctance to consider vaccination, as one of the world's top 10 public health challenges.

"And we saw the effects of that," Najera said. "We saw a rise of measles in the United States to the point where the elimination status of the United States for measles was in jeopardy."

Najera is confident vaccine opponents aren't going away. He says, if anything, the rise of social media has made it easier for them to spread their message. What he finds most frustrating is that these anti-vaccines protesters aren't just making choices that affect their own families. Najera says choosing not to vaccinate their children and joining other large protests to spread their message puts the health of everyone at risk.

This content is from Southern California Public Radio. View the original story at SCPR.org.

Jordan Trimble of Skyharbour Resources lays out the reasons why the uranium bear market is coming to an end, and why his company is poised to take advantage of the upturn, in this conversation with Maurice Jackson of Proven and Probable.

Tom Rachal (R) receives a free meningitis vaccine from Dr. Wayne Chen at the AIDS Healthcare Foundation pharmacy on April 15, 2013 in Hollywood, California. Los Angeles County's unemployment rate is 7.9%, down from 9.2% a year ago, and once again it was healthcare that added the most jobs: 22,000.
; Credit: Kevork Djansezian/Getty Images

If you want a job in Los Angeles County, you’re best off being a nurse or a hotel worker and you’re less likely to find employment in manufacturing. 

We’re getting our first look at the employment numbers for 2014, which show mostly good news: California’s unemployment has fallen to 7 percent, the lowest rate in five and a half years. (The final numbers come out in March)

The state’s job growth outpaced the rest of the country for the third straight year, though it slowed slightly towards the end of the year.

California added jobs at a 2.2 percent annual rate last year, outpacing the nation’s 1.8 percent rate. 

Los Angeles County fared the worst as far as seasonally adjusted year-to-year job gains among California's major metropolitan areas, according to The Los Angeles County Economic Development Corp.:

• San Jose/Silicon Valley +4 percent
• San Francisco Bay Area + 3.8 percent 
• San Diego +3.3 percent
• Inland Empire +1.9 percent
• Orange County +2.3 percent
• Ventura +2 percent
• Los Angeles +1.7 percent

Los Angeles County's unemployment rate is 7.9 percent, down from 9.2 percent a year ago, and once again it was health care that added the most jobs: 22,000.

"Part of it is demographic, and part of it was the Affordable Care Act, which is helping more individuals take advantage of health care," said Robert Kleinhenz, Chief Economist at the L.A. County Economic Development Corp.

Aside from an aging population needing more health care, Kleinhenz adds that more people can afford to get medical treatment because of the improvement in the economy. 

With more money in their pockets, more people have also been traveling, which made leisure and hospitality the second-best area for job growth in the county, with 11,300 new jobs.

What's not doing well? 

Manufacturing, especially in non-durable goods – which includes food and clothing – lost the most jobs in L.A. County in 2014: 6,700 jobs. The only other sector that shed jobs was the government, which lost almost 3,800 jobs positions last year.

Kleinhenz also pointed to wholesale trade, which lost 300 jobs year-to-year in but saw job growth in the Inland Empire. 

"Some parts of the goods movement may be moving into the Inland Empire, where we have seen in recent years quite a bit of warehouse building taking place,” said Kleinhenz. 

This content is from Southern California Public Radio. View the original story at SCPR.org.

Full Text:

The molecular mechanism used by many bacteria to kill neighboring cells has redundancy built into its genetic makeup, which could allow for the mechanism to be expressed in different environments, say researchers at Penn State and the University of Wisconsin-Madison. Their new study provides insights into the molecular mechanisms of competition among bacteria. "Many organisms, including humans, acquire bacteria from their environment," said Tim Miyashiro, a biochemist and molecular biologist at Penn State and the leader of the research team. "These bacteria can contribute to functions within the host organism, like how our gut bacteria help us digest food. We're interested in the interactions among bacteria cells, and between bacteria and their hosts, to better understand these mutually beneficial symbiotic relationships." Cells of the bioluminescent bacteria Vibrio fisheri take up residence in the light organ of newly hatched bobtail squid. At night, the bacteria produce a blue glow that researchers believe obscures a squid's silhouette and helps protect it from predators. The light organ has pockets, or crypts, in the squid's skin that provide nutrients and a safe environment for the bacteria. "When the squid hatches, it doesn't yet have any bacteria in its light organ," said Miyashiro. "But bacteria in the environment quickly colonize the squid's light organ." Some of these different bacteria strains can coexist, but others can't. "Microbial symbioses are essentially universal in animals, and are crucial to the health and development of both partners," says Irwin Forseth, a program director in the National Science Foundation's Division of Integrative Organismal Systems, which funded the research. "The results from this study highlight the role small genetic changes can play in microbe interactions. Increased understanding will allow us to better predict organisms' performance in changing environments."

Image credit: Andrew Cecere

Source: Streetwise Reports   05/06/2020

In a May 4 research note, H.C. Wainwright & Co. analyst Ed Arce reported that Arcturus Therapeutics Holdings Inc. (ARCT:NASDAQ) formed a partnership with Catalent Inc. (CTLT:NYSE), which "raises the profile of LUNAR-COV19 as a leading vaccine candidate."

Arce reviewed Catalent's contribution to the partnership. The global contract development and manufacturing organization is to manufacture Arcturus' messenger RNA (mRNA) LUNAR-COV19 for protection against SARS-CoV-2 to be used first for human clinical trials and potentially, eventually commercially.

As for timing, Arce noted, San Diego, Calif.-based Arcturus intends to transfer its vaccine technology to Catalent this month and expects Catalent to manufacture the first batches of LUNAR-COV19 by June 2020. "Critically, Arcturus continues to anticipate initiation of Phase 1 testing of LUNAR-COV19 in the summer of 2020," Arce highlighted.

Catalent is to produce the vaccine at its biomanufacturing facility in Madison, Wisc. "This facility utilizes Catalent's flex-suite, a current good manufacturing practice manufacturing suite, that can produce batches at multiple scales and support Arcturus' proprietary mRNA manufacturing process," explained Arce.

Obtaining the vaccine from one facility domestically versus multiple entities worldwide should result in several benefits, Arce continued. They include easy development and production, accelerated delivery and improved costs. Arcturus believes Catalent can produce millions of doses of LUNAR-COV19 mRNA in 2020 and, if need be, hundreds of millions of doses each year subsequently for use globally.

Arce pointed out that LUNAR-COV19 differentiates itself from other similar vaccine candidates in that the technology and delivery platform behind it deliver an "extraordinarily low dose (perhaps 2 micrograms)" in "a potential single shot."

H.C. Wainwright has a Buy rating and a $62 per share price target on Arcturus, the stock of which is currently trading at about $42.12 per share.

Disclosure:
1) Doresa Banning compiled this article for Streetwise Reports LLC and provides services to Streetwise Reports as an independent contractor. She or members of her household own securities of the following companies mentioned in the article: None. She or members of her household are paid by the following companies mentioned in this article: None.
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Disclosures from H.C. Wainwright & Co., Arcturus Therapeutics Holdings Inc., First Take, May 4, 2020

Investment Banking Services include, but are not limited to, acting as a manager/co-manager in the underwriting or placement of securities, acting as financial advisor, and/or providing corporate finance or capital markets-related services to a company or one of its affiliates or subsidiaries within the past 12 months.

I, Ed Arce, certify that 1) all of the views expressed in this report accurately reflect my personal views about any and all subject securities or issuers discussed; and 2) no part of my compensation was, is, or will be directly or indirectly related to the specific recommendation or views expressed in this research report; and 3) neither myself nor any members of my household is an officer, director or advisory board member of these companies.

None of the research analysts or the research analyst's household has a financial interest in the securities of Arcturus Therapeutics Holdings Inc. (including, without limitation, any option, right, warrant, future, long or short position).

As of April 30, 2020 neither the Firm nor its affiliates beneficially own 1% or more of any class of common equity securities of Arcturus Therapeutics Holdings Inc.

Neither the research analyst nor the Firm has any material conflict of interest in of which the research analyst knows or has reason to know at the time of publication of this research report.

The research analyst principally responsible for preparation of the report does not receive compensation that is based upon any specific investment banking services or transaction but is compensated based on factors including total revenue and profitability of the Firm, a substantial portion of which is derived from investment banking services.

The firm or its affiliates received compensation from Arcturus Therapeutics Holdings Inc. for non-investment banking services in the previous 12 months.

The Firm or its affiliates did receive compensation from Arcturus Therapeutics Holdings Inc. for investment banking services within twelve months before, and will seek compensation from the companies mentioned in this report for investment banking services within three months following publication of the research report.

H.C. Wainwright & Co., LLC managed or co-managed a public offering of securities for Arcturus Therapeutics Holdings Inc. during the past 12 months.

The Firm does not make a market in Arcturus Therapeutics Holdings Inc. as of the date of this research report.

H.C. Wainwright & Co., LLC and its affiliates, officers, directors, and employees, excluding its analysts, will from time to time have long or short positions in, act as principal in, and buy or sell, the securities or derivatives (including options and warrants) thereof of covered companies referred to in this research report.

( Companies Mentioned: ARCT:NASDAQ, )

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