ria

Tears for Syria

Initiating conversation with a man at the entrance of the Syrian club, Ben* learnt about his pain and encouraged him to consider God's truth.




ria

Brian Beacom: Dating in the modern world

GREAT news. I think. Glasgow is a great place in which to be looking for love, with 44 per cent of the city single, according to an online dating company.Why does this matter? Flash back to Valentine’s Day. There I was, lying in a pool of poetical blood, having been shot in the heart with the killer question no single man over a certain age wants to hear: “How many Valentine’s cards did you get?” asked a friend.




ria

Participants share about refugee outreach in Austria

Thirteen participants from all over the world spent a week getting to know and supporting the refugee work in Linz. Six share about their experiences.




ria

From Africa to Austria

Leon and Santjie Potgieter arrive in Austria to work with a church in Linz and help with church planting.




ria

Austrian summer outreach

Stories from ReachAUT, an outreach in Austria organised by the Liebenzeller Mission in cooperation with other Christian organisations, including OM.




ria

From Siberia to South Africa to Scotland, plan now for a truly unusual post-lockdown break

HOLIDAYS may be temporarily on hold, but planning magical trips is still possible. Spontaneity shapes thrilling travel escapades, but there's also a case for careful, methodical planning. Often, the preparation – deciding on a route, reading up about a destination – can be just as enjoyable as the trip itself.




ria

Penev offers grassroots support in Bulgaria

Bulgaria coach Luboslav Penev and his staff encouraged over 120 children taking part in a grassroots event in Sofia designed to increase participation in football and other sports.




ria

Tycoon who bought Craig Whyte castle to stand trial

A Russian tycoon who bought former Rangers owner Craig Whyte’s Highland castle is to stand trial over an alleged £8 million fraud.




ria

'Fresh street food. In the house. Hard to beat' – Ron Mackenna's home delivery eating in review: Lebanese Street Sajeria

Thyme: Lebanese Street Sajeria




ria

David Torrance: Airstrikes in Syria are far from ideal, but it’s better than nothing

Today in the House of Commons, the Prime Minister will explain her decision to authorise airstrikes against Syria alongside France and the United States.




ria

Celebrities like Victoria Beckham should be paying up in the coronavius crisis

THE Through the Keyhole Pandemic Special has certainly given rise to some entertaining sights.




ria

Iain Macwhirter: Alex Salmond ... the trial that could split the SNP from top to bottom

The Scottish political world is holding its breath this weekend.




ria

Khan App Boosted Early Literacy, Parent Teaching in Small Trial

The free literacy app Khan Academy Kids boosted early literacy skills in children and parents said it improved their home-teaching skills.




ria

Obituary: Brian Dennehy, imposing actor whose range spanned grizzled cops and Willy Loman

Born: July 9, 1938;




ria

Judge Allows Lawsuit Against Pop Warner to Proceed to Trial

A Los Angeles judge ruled that a teenage football player may proceed to trial against the national Pop Warner organization, four years after he suffered an on-field injury that left him a quadriplegic.




ria

Bavaria to host Regions' Cup in June

Bavaria will host the eight-team UEFA Regions' Cup finals from 18 to 26 June.




ria

Camley’s Cartoon round-up: Royal crisis, CalMac latest, Brian Cox and more

Monday 13 January: Royals’ family meeting




ria

Colette Douglas Home: Far from an easy choice in deciding to launch strikes over Syria

An armoured car guarded the Grand Place in Brussels city centre yesterday as a group of women sat drinking coffee at an outdoor table. A reporter asked one of them what she would do if terrorists started shooting? She said: "Smile. Sit. Drink coffee. Enjoy – even if it is the last."




ria

The Hysteria Over Face Recognition

The fear is that instead of using it to prevent crime and catch terrorists, facial recognition is instead used for political purposes. But we won't stop it or protect privacy by freaking out.




ria

Reducir la deforestación e incrementar captura de CO2 en el suelo, una estrategia climática y de seguridad alimentaria

Source: El Periódico - Las políticas climáticas que se centran en la agricultura y los bosques podrían llevar al aumento de los precios de los alimentos, pero reducir la deforestación e incrementar la captura de carbono en la agricultura podría reducir significativamente las emisiones de gases de efecto invernadero, evitando riesgos para la seguridad alimentaria, según un nuevo estudio publicado en 'Environmental Research Letters'.




ria

Noninvasive Ventilation for Respiratory Distress Syndrome: A Randomized Controlled Trial

Nasal continuous positive airway pressure (NCPAP) has been the initial respiratory support for many preterm infants with respiratory distress syndrome (RDS). Nasal intermittent positive-pressure ventilation (NIPPV) seems to increase the beneficial effects of NCPAP by combining it with ventilatory inflations.

This study suggests that NIPPV, as an intial respiratory support for preterm infants with RDS, is feasible and safe and may have beneficial effects, when compared with NCPAP. (Read the full article)




ria

Prospective Assessment of Practice Pattern Variations in the Treatment of Pediatric Gastroenteritis

Although gastroenteritis guidelines describe the need to perform oral rehydration, it remains underused, resulting in excessive use of intravenous rehydration. Other interventions, such as antiemetic administration, vary according to location, often resulting in differences in cost and outcomes.

In this nationwide cohort, intravenous rehydration use varied dramatically. Use was associated with the institution providing care and an increase in the need for future health care provider visits. Use of ondansetron also varied significantly across Canada. (Read the full article)




ria

Corticosteroid Pulse Combination Therapy for Refractory Kawasaki Disease: A Randomized Trial

The efficacy of intravenous immunoglobulin and corticosteroid pulse combination therapy for refractory Kawasaki disease has been established. The Egami score can be used to predict which patients are likely to have refractory Kawasaki disease.

As a new strategy for primary treatment, intravenous immunoglobulin and corticosteroid pulse combination therapy is safe and effective for patients predicted to have refractory Kawasaki disease based on the Egami score. (Read the full article)




ria

Wide Variation in Reference Values for Aluminum Levels in Children

Aluminum is ubiquitous and exposure is unavoidable. Adverse health effects have been associated with large exposures in workers or those with chronic kidney disease. There are no established age-specific reference ranges or toxicity data for populations of healthy children.

We demonstrate the wide variability of aluminum reference ranges in biological samples and that the ranges are not based on studies including healthy children. Further research is necessary to establish clinically relevant reference ranges for healthy children. (Read the full article)




ria

Peer-led Education for Adolescents With Asthma in Jordan: A Cluster-Randomized Controlled Trial

The prevalence of asthma and smoking among adolescents in Jordan is high. Well-designed, school-based, peer-led education programs can have a positive impact on asthma self-management in adolescents. Student peer leaders can be useful and responsible partners in health promotion programs.

A peer-led asthma education program —Adolescent Asthma Action—for adolescents developed in Australia was adapted to suit non–English-speaking cultures in the Middle East. Peer-led education led to improved self-management of asthma and motivated students to avoid smoking. (Read the full article)




ria

US Estimates of Hospitalized Children With Severe Traumatic Brain Injury: Implications for Clinical Trials

Clinical trials in children with severe traumatic brain injury (TBI) are challenging. To date, no work has been published that permits clinical investigators to estimate the number and compositional features of sites from which to recruit children with severe TBI into clinical trials.

Children with severe TBI are infrequent. Less than 5% of all US hospitals discharged more than 78% of severe TBI cases. To maximize enrollment efficiency for future clinical trials, attention has to be paid to selecting appropriate hospital sites. (Read the full article)




ria

Early Intervention Improves Behavioral Outcomes for Preterm Infants: Randomized Controlled Trial

Prematurely born children have an increased prevalence of behavioral problems in the long term. Knowledge regarding the effects of early intervention programs is sparse, and more randomized controlled trials are warranted.

A modified version of the Mother-Infant Transaction Program showed beneficial effects on behavioral outcomes reported by both parents of preterm infants with birth weights of <2000 g at a corrected age of 5 years. (Read the full article)




ria

Bovine Lactoferrin Prevents Invasive Fungal Infections in Very Low Birth Weight Infants: A Randomized Controlled Trial

Lactoferrin is a glycoprotein with anti-infective activities being part of the innate defensive network. Bovine and human lactoferrin share high homology. Bovine lactoferrin can prevent late-onset sepsis in preterm very low birth weight neonates.

In preterm very low birth weight infants, bovine lactoferrin is able to prevent not only late-onset sepsis but also systemic fungal infections. This protection is achieved independently from their colonization status. (Read the full article)




ria

Oral Sucrose and "Facilitated Tucking" for Repeated Pain Relief in Preterms: A Randomized Controlled Trial

Preterm infants are exposed to inadequately managed painful procedures during their NICU stay, which can lead to altered pain responses. Nonpharmacologic approaches are established for the treatment of single painful procedures, but evidence for their effectiveness across time is lacking.

Oral sucrose with or without the added technique of facilitated tucking has a pain-relieving effect even in extremely premature infants undergoing repeated pain exposures; facilitated tucking alone seems to be less effective for repeated pain exposures over time. (Read the full article)




ria

Randomized Trial of Oral Versus Sequential IV/Oral Antibiotic for Acute Pyelonephritis in Children

The standard initial management for infants and children with acute pyelonephritis is intravenous antibiotic treatment.

Our results support the use of an oral cefixime treatment of initial episodes of acute pyelonephritis involving a gram-negative bacteria strain in children aged 1 month to 3 years who are without urological abnormalities and without clinical hemodynamic impairment. (Read the full article)




ria

Resilience in Children Undergoing Stem Cell Transplantation: Results of a Complementary Intervention Trial

Children undergoing stem cell transplantation are thought to be at risk for increased distress, adjustment difficulties, and impaired health-related quality of life. Few interventions to improve adjustment and quality-of-life outcomes in this setting have been tested.

The excellent outcomes observed in all patient groups, including controls, may be a result of improvements in standard supportive care. Stem cell transplantation may not be as demanding as previously thought to be, and children undergoing this procedure appear resilient to the challenge. (Read the full article)




ria

Variation in Teen Driver Education by State Requirements and Sociodemographics

Most states require driver education (DE) for novice drivers, and several recent substantial efforts have sought to realign DE with the aim of producing safer drivers. However, teen participation rates and how they differ among relevant subgroups remain unknown.

This study provides national estimates of teen driver participation in formal DE, a recognized gap in the literature, and identifies disparities in behind-the-wheel training among certain racial/ethnic, socioeconomic, and gender groups, particularly in jurisdictions without a DE requirement. (Read the full article)




ria

Impaired Fetal Growth and Arterial Wall Thickening: A Randomized Trial of Omega-3 Supplementation

Impaired fetal growth is an independent risk factor for cardiovascular diseases in adulthood and is associated with arterial wall thickening, a noninvasive measure of subclinical atherosclerosis, in early childhood. No preventive strategy has been identified.

Dietary omega-3 fatty acid supplementation in early childhood prevented the association of impaired fetal growth with arterial wall thickening, suggesting that this early-life intervention may mitigate the risk of cardiovascular disease in those with impaired fetal growth. (Read the full article)




ria

A Statewide Trial of the SafeCare Home-based Services Model With Parents in Child Protective Services

Neglect cases in Child Protective Services often receive home-based interventions, but their success in preventing maltreatment recidivism has been elusive. Structured, behavioral skills models, such as SafeCare, are promising but have not been tested in full-scale implementation trials.

This cluster trial experiment demonstrates significant maltreatment recidivism reduction due to implementing the SafeCare model in a fully scaled-up statewide system. The findings support adopting the SafeCare model for these types of services. (Read the full article)




ria

Clinic-Integrated Behavioral Intervention for Families of Youth With Type 1 Diabetes: Randomized Clinical Trial

Strategies to assist patients in achieving optimal chronic disease self-management are critical. The complex family and regimen issues surrounding pediatric type 1 diabetes management suggest the need to integrate such strategies into routine clinical care.

This study demonstrates the efficacy of a practical, low-intensity behavioral intervention delivered during routine care for improving glycemic outcomes. Findings indicate that the approach may offer a potential model for integrating medical and behavioral sciences to improve health care. (Read the full article)




ria

Breast Milk and Glucose for Pain Relief in Preterm Infants: A Noninferiority Randomized Controlled Trial

Numerous late preterm infants undergo repetitive heel lancing procedures during their first hours of life to evaluate glycemic control. Heel lances are painful and 25% glucose solution is effective on reducing procedural neonatal pain scores and crying behavior.

This noninferiority randomized controlled trial demonstrated that compared with breast milk, 25% glucose provided lower pain scores and reduced duration of cry. Further research is necessary to clarify breast milk’s mechanisms and efficacy on neonatal pain relief. (Read the full article)




ria

A Randomized Controlled Trial of Zinc as Adjuvant Therapy for Severe Pneumonia in Young Children

Pneumonia is still a significant problem in young children from developing countries where zinc deficiency is prevalent. Although zinc supplementation reduces the risk of childhood pneumonia, the effect of adjunct zinc on severe pneumonia is unclear with conflicting results.

The overall effect, if any, of zinc as adjuvant therapy for World Health Organization–defined severe pneumonia in young children is small. (Read the full article)




ria

Hospital Variation in Nitric Oxide Use for Premature Infants

Inhaled nitric oxide for premature infants has been evaluated in multiple studies; however, these trials differed in treatment initiation, duration of therapy, and inclusion criteria. Furthermore, these trials reached differing conclusions regarding the benefit of inhaled nitric oxide.

We used a large sample of infants from children’s hospitals and found that the use of inhaled nitric oxide in premature infants was variable even when controlling for demographic characteristics and disease. (Read the full article)




ria

Triage Nurse Initiation of Corticosteroids in Pediatric Asthma Is Associated With Improved Emergency Department Efficiency

Early administration of oral corticosteroids is essential for children presenting to emergency departments with moderate to severe acute asthma exacerbations, because subsequent admission need is directly related to time to receipt of systemic steroids, yet delays to administration remain long.

A medical directive allowing nurse initiation of oral corticosteroids before physician assessment was associated with improved quality and efficiency of care provided in the pediatric emergency department by ensuring implementation of evidence-based practice. (Read the full article)




ria

Tight Glycemic Control With Insulin in Hyperglycemic Preterm Babies: A Randomized Controlled Trial

Insulin is commonly used to treat neonatal hyperglycemia, but there are few data to support its use. Tight glycemic control with insulin improves outcome in diabetic patients, but it is not known whether it is effective in hyperglycemic preterm infants.

Tight glycemic control with insulin in hyperglycemic preterm neonates decreases the rate of linear growth despite increased weight and occipitofrontal head circumference gain and increases the risk of hypoglycemia. Insulin may not be a safe and effective treatment in hyperglycemic preterm neonates. (Read the full article)




ria

Randomized Trial of Probiotics and Calcium on Diarrhea and Respiratory Tract Infections in Indonesian Children

Some but not all randomized trials have shown effects of probiotics on incidence and duration of diarrhea and respiratory tract infections among children in developing countries. Calcium improves resistance to intestinal infections in adults, but efficacy in children is unknown.

Lactobacillus reuteri DSM17938 may prevent diarrhea, especially in children with lower nutritional status. Regular calcium milk, alone or with Lactobacillus casei CRL431, did not reduce diarrhea. None of the interventions affected respiratory tract infections in these Indonesian children. (Read the full article)




ria

Early or Delayed Enteral Feeding for Preterm Growth-Restricted Infants: A Randomized Trial

Preterm, growth-restricted infants are at high risk of necrotizing enterocolitis (NEC). NEC occurs most frequently in infants who have received enteral feeds. It is common practice to delay introduction of enteral feeds in these infants.

Early introduction of enteral feeds results in earlier achievement of full enteral feeding. Early feeding is not associated with a higher risk of NEC. Delayed feeding is associated with a higher risk of cholestasis. (Read the full article)




ria

Supplemental Written Information Improves Prenatal Counseling: A Randomized Trial

During prenatal counseling for prematurity, information is provided to expectant parents to empower them to participate in the medical-care decision-making regarding their child. However, numerous studies have shown that providing information effectively during preterm labor is challenging.

The current study provides evidence that effectiveness of counseling can be improved by providing written information to parents before the face-to-face verbal counseling. Appropriately presented, detailed information improves knowledge and decreases maternal anxiety. (Read the full article)




ria

Long-term Effectiveness of Maternal Dietary Counseling in a Low-Income Population: A Randomized Field Trial

Recent systematic reviews revealed that educational dietary interventions were effective in improving nutritional status and food consumption in the first year after birth. We are not aware, however, of studies in developing countries that have evaluated their long-term effectiveness.

This randomized trial revealed that, in a low-income population, the delivery of home-based maternal counseling focusing on breastfeeding and complementary feeding during the first year of children’s lives significantly improved the lipid profile at 7 to 8 years old. (Read the full article)




ria

Computer-Facilitated Substance Use Screening and Brief Advice for Teens in Primary Care: An International Trial

Primary care settings provide an important venue for early detection of substance use and intervention, but adolescent screening rates need improvement. Screening and brief interventions appear effective in reducing adult problem drinking but evidence for effectiveness among adolescents is needed.

A computer-facilitated system for screening, feedback, and provider brief advice for primary care can increase adolescent receipt of substance use screening across a variety of practice settings, and shows promise for reducing adolescents’ use of alcohol and cannabis. (Read the full article)




ria

Oral Dimenhydrinate Versus Placebo in Children With Gastroenteritis: A Randomized Controlled Trial

Dimenhydrinate, an antihistaminic agent, is a widely used drug in Canada and Europe. It limits stimulation of the vomiting center via the vestibular system. Multiple studies have shown its effectiveness in the treatment of vertigo and postoperative nausea and vomiting.

Dimenhydrinate, when given orally, did not significantly decrease the frequency of vomiting in children with acute gastroenteritis compared with placebo. The reported adverse effect proportions were similar for the dimenhydrinate and placebo groups. (Read the full article)




ria

Randomized Trial of Sumatriptan and Naproxen Sodium Combination in Adolescent Migraine

Treatment of adolescent migraine remains a significant unmet medical need. In adults, the combination of sumatriptan and naproxen sodium has demonstrated superior efficacy, with similar tolerability, to its components in the acute treatment of migraine.

This study constitutes the first large-scale, placebo-controlled evidence for the acute relief of adolescent migraine pain and associated symptoms with an oral medication. (Read the full article)




ria

A Double-Blind, Placebo-Controlled Trial of Omega-3 Fatty Acids in Tourette's Disorder

Omega-3 fatty acids (O3FA) are commonly used as complementary treatments in pediatric psychiatric disorders, including Tourette’s disorder (TD), and are well known to have anti-inflammatory properties. However, no studies to date have examined the effects of O3FA on pediatric TD.

This is the first double-blind, placebo-controlled clinical trial of O3FA in pediatric TD. The results indicate that O3FA supplementation may be beneficial in the reduction of tic-related impairment for some children and adolescents with TD, but not tics per se. (Read the full article)




ria

Pediatric Versus Adult Drug Trials for Conditions With High Pediatric Disease Burden

Many drugs are not approved for use in pediatric patients and there is limited evidence on their safety and efficacy in children. Furthermore, there is concern that the quality of pediatric trials is inferior compared with adult trials.

For conditions with a high disease burden in children, only a small proportion of clinical drug trials study pediatric patients. Most pediatric trials are not funded by industry, and the deficiency of evidence is largest in developing countries. (Read the full article)




ria

Maternal HIV Infection and Vertical Transmission of Pathogenic Bacteria

Neonatal sepsis is an important cause of under-5 childhood mortality. Infants born to HIV-infected mothers are at increased risk of morbidity and mortality, even if not having acquired HIV. This association needs further study during the neonatal period.

Maternal HIV infection was associated with increased vaginal colonization by Escherichia ecoli but not group B Streptococcus. Neonates born to HIV-infected mothers were only at increased risk of sepsis if they had acquired HIV-infection, but not if HIV-uninfected. (Read the full article)