Collecting and analyzing real-time data on the number of cases and deaths during a disease outbreak is crucial. Here's why we've failed.

View our map and graphics to see where COVID-19 is hitting hardest in the U.S., which state outbreaks are growing the fastest and which are leveling off.

A map of confirmed COVID-19 cases and deaths around the world. The respiratory disease has spread rapidly across six continents and has killed thousands of people.

Alabama's Henry Ruggs appears to be the fastest receiver to enter the NFL draft, and he thinks he can be better in the pros.

How does the Los Angeles Times coronavirus tracker work? The people who built and maintain it explain.

Two-thirds of Keara Williams' 24 AP English students haven't turned in assignments. She spent Friday trying to find them.

Ferrari's 488 Pista, which replaces the 458 Speciale, is driven by the most powerful V8 engine Ferrari has ever put in a road car.

As the all-out effort for a vaccine accelerates, USA TODAY is rounding up some of the week's most notable developments.

The president of Texas Motor Speedway is still hoping to run the Genesys 600 with fans in June. But if they're turned away, he'll need NASCAR's help.

The White House has had to correct its facts about the killing of Bin Laden, and for some that has diminished the glow of success that has surrounded all those involved in the operation.

Bin Laden wasn't armed when he was shot. It raises suspicions that this was indeed a deliberate shoot-to-kill operation.

Here are the inaccuracies in the first version. The woman killed was not his wife. No woman was used as a human shield. And he was not armed.

The president's press secretary Jay Carney suggested this was the result of trying to provide a great deal of information in a great deal of haste.

I can largely accept that. There is no mileage in misleading people and then correcting yourself. But the president's assistant national security advisor John Brennan had used the facts he was giving out to add a moral message - this was the sort of man Bin Laden was, cowering behind his wife, using her as a shield. Nice narrative. Not true. In fact, according to Carney this unarmed woman tried to attack the heavily armed Navy Seal. In another circumstance that might even be described as brave.

Jay Carney said that Bin Laden didn't have to have a gun to be resisting. He said there was a great deal of resistance in general and a highly volatile fire fight. The latest version says Bin Laden's wife charged at the US commando and was shot in the leg, but not killed. The two brothers, the couriers and owners of the compound, and a woman were killed on the ground floor of the main building. This version doesn't mention Bin Laden's son, who also died.

By this count only three men, at the most, were armed. I do wonder how much fight they could put up against two helicopters' worth of Navy Seals.

Does any of this matter? Well, getting the fact right is always important. You can't make a judgment without them. We all make mistakes, and journalists hate doing so because it makes people trust us less. For those involved an operation like this, time must go past in a confused and noisy instant, and they aren't taking notes. Confusion is very understandable. But you start to wonder how much the facts are being massaged now, to gloss over the less appealing parts of the operation.

And of course there is the suspicion that the US never wanted to take Bin Laden alive. Here at least many see a trial as inconvenient, awkward - a chance for terrorists to grandstand. Look at all the fuss about the trial of Khalid Sheikh Mohammed.

In the confusion of a raid it's hard to see how the Seals could be sure that Bin Laden wasn't armed, didn't have his finger on the trigger of a bomb, wasn't about to pull a nasty surprise. If he had his hands in the air shouting "don't shoot" he might have lived, but anything short of that seems to have ensured his death.

I suspect there will be more worry about this in Britain and Europe than in the US. That doesn't mean we are right or wrong. It is a cultural difference. We are less comfortable about frontier justice, less forgiving about even police shooting people who turn out to be unarmed, perhaps less inculcated with the Dirty Harry message that arresting villains is for wimps, and real justice grows from the barrel of a gun. Many in America won't be in the slightest bit bothered that a mass murderer got what was coming to him swiftly, whether he was trying to kill anyone in that instant or not.

PM Scott Morrison said wide usage would be the "ticket" to normal life resuming as soon as possible.

US space agency satellites follow the melting trends in Antarctica and Greenland over 16 years.

A team of researchers from Dartmouth say they’ve created a mobile sensing system — consisting of fitness bracelets, sensors and a custom app — that can measure employee performance with about 80 percent accuracy.

strataconf: Read our initial findings of @amplab's open source benchmark for tracking large-scale Query Engines http://t.co/rGgOVeTHQ8 #strataconf

BEST FITNESS TRACKER DEALS:

• Fitbit - Charge 3 Activity Tracker + Heart Rate — $99.95 (save $30)

• Garmin - Forerunner 645 Music GPS Heart Rate Monitor Running Watch — $449.99

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Wellness is a buzzy word lately. Over the past few years, we’ve seen a surge in all things health, wellness, and spirituality. Juice bars are popping up, boutique studios are becoming more accessible, and essential oils are chilling us out. Self-care is becoming more of the norm too, but amidst all this hype, it can be challenging to find the right routine that promotes good exercise, sleep, vitals, and mindset.  Read more...

The Fiat-Chrysler Windsor Assembly Plant looks to be on track for a May 19 reopening according to union leadership.

Reactive oxygen and nitrogen species have been implicated in many biological processes and diseases, including immune responses, cardiovascular dysfunction, neurodegeneration, and cancer. These chemical species are short-lived in biological settings, and detecting them in these conditions and diseases requires the use of molecular probes that form stable, easily detectable, products. The chemical mechanisms and limitations of many of the currently used probes are not well-understood, hampering their effective applications. Boronates have emerged as a class of probes for the detection of nucleophilic two-electron oxidants. Here, we report the results of an oxygen-18–labeling MS study to identify the origin of oxygen atoms in the oxidation products of phenylboronate targeted to mitochondria. We demonstrate that boronate oxidation by hydrogen peroxide, peroxymonocarbonate, hypochlorite, or peroxynitrite involves the incorporation of oxygen atoms from these oxidants. We therefore conclude that boronates can be used as probes to track isotopically labeled oxidants. This suggests that the detection of specific products formed from these redox probes could enable precise identification of oxidants formed in biological systems. We discuss the implications of these results for understanding the mechanism of conversion of the boronate-based redox probes to oxidant-specific products.

(Tokyo University of Science) Plastic waste often ends up in river bodies and oceans, posing a serious threat to the marine ecosystem. To prevent the accumulation of plastic debris, we must find out where plastic emission is prevalent. To this end, scientists in Japan have come up with a new method to track plastic emissions from inland areas to sea. This method is useful to identify the 'hotspots' of plastic emission and can even help to implement appropriate measures to avoid plastic pollution.

As part of the College's move to remote learning, 143 first-year students are taking a series of virtual field courses to investigate biodiversity.

Imagine some of your favourite artistes on one song, offering up messages of encouragement and upliftment. Well, that is the concept behind the latest track from Billboard-charting producer NotNice. Dubbed We Are, the song features vocals from...

This week our host Scott Carey is joined by Techworld editor Charlotte Jee to discuss the revelation that Google is still tracking users, even if you have that feature disabled, and the wider topic of privacy.

Then games editor at Tech Advisor, Lewis Painter, joins to talk about one of the most hotly anticipated games of the year: Red Dead Redemption 2.

Lastly Macworld UK editor Karen Khan talks about the enduring legacy of the iMac PC 20 years on and how it set Apple on a historic trajectory.

See acast.com/privacy for privacy and opt-out information.

Type 2 diabetes mellitus predicts outcome following acute myocardial infarction (AMI). Since underlying mechanics are incompletely understood, we investigated left ventricular (LV) and atrial (LA) pathophysiological changes and their prognostic implications using cardiovascular magnetic resonance (CMR). Consecutive patients (n=1147, n=265 diabetic; n=882 non-diabetic) underwent CMR 3 days after AMI. Analyses included LV ejection fraction (LVEF), global longitudinal, circumferential and radial strains (GLS, GCS and GRS), LA reservoir, conduit and booster pump strains, as well as infarct size, edema and microvascular obstruction. Predefined endpoints were major adverse cardiovascular events (MACE) within 12 months. Diabetic patients had impaired LA reservoir (19.8 vs. 21.2%, p<0.01) and conduit strains (7.6 vs. 9.0%, p<0.01) but not ventricular function or myocardial damage. They were at higher risk of MACE than non-diabetic patients (10.2% vs. 5.8%, p<0.01) with most MACE occurring in patients with LVEF≥35%. Whilst LVEF (p=0.045) and atrial reservoir strain (p=0.024) were independent predictors of MACE in non-diabetic patients, GLS was in diabetic patients (p=0.010). Considering patients with diabetes and LVEF≥35% (n=237), GLS and LA reservoir strain below median were significantly associated with MACE. In conclusion, in patients with diabetes, LA and LV longitudinal strain permit optimized risk assessment early after reperfused AMI with incremental prognostic value over and above LVEF.

1 June 2012 , Volume 68, Number 4

Eyes in the skies keeping watch on a planet under stress. Click on the PDF link to view the graphic

REGGAE ARTISTE Isha Blender is still coming to terms with the loss of her son, Josiah, on January 5, a mere two days after she celebrated her birthday. The daughter of legendary crooner Everton Blender said the death of a child can be one of the...

Supreme Ventures Racing and Entertainment Limited, operators of Caymanas Track, has announced the re-opening of the main track, effective tomorrow. The company said in a press release on Thursday evening that the track will be opened for two days...

Officials said 15 migrant workers were killed Friday when a cargo train ran them over as they slept on the tracks near Aurangabad, India.

When schools reduce racial segregation between schools, racial isolation within the classes inside those schools goes up, according to an analysis of 20 years of North Carolina data.

It's worth remembering how far we've come on educating students with disabilities, writes Nebraska's education commissioner Matthew L. Blomstedt.

It's worth remembering how far we've come on educating students with disabilities, writes Nebraska's education commissioner Matthew L. Blomstedt.

It's worth remembering how far we've come on educating students with disabilities, writes Nebraska's education commissioner Matthew L. Blomstedt.

Fed up with their district’s unmet pledges to stop steering African American students into low-level classes, parents take action.

The Chinese Communist Party (CCP) is building links between China’s civilian universities, military and security agencies. Those efforts, carried out under a policy of leveraging the civilian sector to maximise military power (known as ‘military–civil fusion’), have accelerated in the past decade. Research for the China Defence Universities Tracker has determined that greater numbers of Chinese universities are engaged in defence research, training defence scientists, collaborating with the military and cooperating with defence industry conglomerates and are involved in classified research.1 At least 15 civilian universities have been implicated in cyberattacks, illegal exports or espionage. China’s defence industry conglomerates are supervising agencies of nine universities and have sent thousands of their employees to train abroad.

This paper develops deterministic upper and lower bounds on the influence measure in a network, more precisely, the expected number of nodes that a seed set can influence in the independent cascade model. In particular, our bounds exploit r-nonbacktracking walks and Fortuin-Kasteleyn-Ginibre (FKG) type inequalities, and are computed by message passing algorithms. Further, we provide parameterized versions of the bounds that control the trade-off between efficiency and accuracy. Finally, the tightness of the bounds is illustrated on various network models.

Gianluca Mastrantonio, Clara Grazian, Sara Mancinelli, Enrico Bibbona.

Source: The Annals of Applied Statistics, Volume 13, Number 4, 2483--2508.

Abstract:
Improved communication systems, shrinking battery sizes and the price drop of tracking devices have led to an increasing availability of trajectory tracking data. These data are often analyzed to understand animal behavior. In this work, we propose a new model for interpreting the animal movent as a mixture of characteristic patterns, that we interpret as different behaviors. The probability that the animal is behaving according to a specific pattern, at each time instant, is nonparametrically estimated using the Logistic-Gaussian process. Owing to a new formalization and the way we specify the coregionalization matrix of the associated multivariate Gaussian process, our model is invariant with respect to the choice of the reference element and of the ordering of the probability vector components. We fit the model under a Bayesian framework, and show that the Markov chain Monte Carlo algorithm we propose is straightforward to implement. We perform a simulation study with the aim of showing the ability of the estimation procedure to retrieve the model parameters. We also test the performance of the information criterion we used to select the number of behaviors. The model is then applied to a real dataset where a wolf has been observed before and after procreation. The results are easy to interpret, and clear differences emerge in the two phases.

Jason Xu, Samson Koelle, Peter Guttorp, Chuanfeng Wu, Cynthia Dunbar, Janis L. Abkowitz, Vladimir N. Minin.

Source: The Annals of Applied Statistics, Volume 13, Number 4, 2091--2119.

Abstract:
Single-cell lineage tracking strategies enabled by recent experimental technologies have produced significant insights into cell fate decisions, but lack the quantitative framework necessary for rigorous statistical analysis of mechanistic models describing cell division and differentiation. In this paper, we develop such a framework with corresponding moment-based parameter estimation techniques for continuous-time, multi-type branching processes. Such processes provide a probabilistic model of how cells divide and differentiate, and we apply our method to study hematopoiesis , the mechanism of blood cell production. We derive closed-form expressions for higher moments in a general class of such models. These analytical results allow us to efficiently estimate parameters of much richer statistical models of hematopoiesis than those used in previous statistical studies. To our knowledge, the method provides the first rate inference procedure for fitting such models to time series data generated from cellular barcoding experiments. After validating the methodology in simulation studies, we apply our estimator to hematopoietic lineage tracking data from rhesus macaques. Our analysis provides a more complete understanding of cell fate decisions during hematopoiesis in nonhuman primates, which may be more relevant to human biology and clinical strategies than previous findings from murine studies. For example, in addition to previously estimated hematopoietic stem cell self-renewal rate, we are able to estimate fate decision probabilities and to compare structurally distinct models of hematopoiesis using cross validation. These estimates of fate decision probabilities and our model selection results should help biologists compare competing hypotheses about how progenitor cells differentiate. The methodology is transferrable to a large class of stochastic compartmental and multi-type branching models, commonly used in studies of cancer progression, epidemiology and many other fields.

Yanjun Qian, Jianhua Z. Huang, Chiwoo Park, Yu Ding.

Source: The Annals of Applied Statistics, Volume 13, Number 3, 1537--1563.

Abstract:
In situ transmission electron microscope (TEM) adds a promising instrument to the exploration of the nanoscale world, allowing motion pictures to be taken while nano objects are initiating, crystalizing and morphing into different sizes and shapes. To enable in-process control of nanocrystal production, this technology innovation hinges upon a solution addressing a statistical problem, which is the capability of online tracking a dynamic, time-varying probability distribution reflecting the nanocrystal growth. Because no known parametric density functions can adequately describe the evolving distribution, a nonparametric approach is inevitable. Towards this objective, we propose to incorporate the dynamic evolution of the normalized particle size distribution into a state space model, in which the density function is represented by a linear combination of B-splines and the spline coefficients are treated as states. The closed-form algorithm runs online updates faster than the frame rate of the in situ TEM video, making it suitable for in-process control purpose. Imposing the constraints of curve smoothness and temporal continuity improves the accuracy and robustness while tracking the probability distribution. We test our method on three published TEM videos. For all of them, the proposed method is able to outperform several alternative approaches.

Bengaluru's all-woman music collective Metronome to release a track for Mother's Day  Times of India

Madagascar, one of the world’s poorest countries, has been mired in political crisis, since 2009, when 34-year-old former radio disc jockey Andry Rajoelina toppled President Marc Ravalomanana in a military coup d’état.

Fed up with their district’s unmet pledges to stop steering African American students into low-level classes, parents take action.

When schools reduce racial segregation between schools, racial isolation within the classes inside those schools goes up, according to an analysis of 20 years of North Carolina data.

The EdWeek Research Center is conducting twice-monthly surveys of teachers and district leaders across the country to help the K-12 system navigate these unprecedented times.

Track how educators and district leaders are responding to challenges related to COVID-19 through recurring surveys from The EdWeek Research Center.

When schools reduce racial segregation between schools, racial isolation within the classes inside those schools goes up, according to an analysis of 20 years of North Carolina data.

YOU report (HeraldScotland, May 5) that Professor Neil Ferguson, one of the UK government’s key advisers on the current lockdown restrictions, has resigned after breaching the government (and his own) strong advice on the need for social distancing.

Children with specific language impairment are at risk for social difficulties. However, whether this occurs adaptively as a result of language impairment or occurs as a result of an underlying deficit in social cognition remains unclear.

We used eye tracking to explore how children with specific language impairment view social scenes. The overall gaze behavior resembled that of typically developing children. Significant attention to the speaker’s mouth may result in receiving less social-emotional information from the eyes. (Read the full article)

A team of social media analysts at an SA business school is tracking misinformation, disinformation, distortion and lies online.