Rockville, Maryland : National Institute on Drug Abuse, 1986.

Rockville, Maryland : National Institute on Drug Abuse, 1986.

Rockville, Maryland : National Institute on Drug Abuse, 1988.

Rockville, Maryland : National Institute on Drug Abuse, 1987.

Rockville, Maryland : National Institute on Drug Abuse, 1987.

Rockville, Maryland : National Institute on Drug Abuse, 1988.

Rockville, Maryland : National Institute on Drug Abuse, 1988.

Rockville, Maryland : National Institute on Drug Abuse, 1988.

Rockville, Maryland : National Institute on Drug Abuse, 1988.

Rockville, Maryland : National Institute on Drug Abuse, 1988.

Rockville, Maryland : National Institute on Drug Abuse, 1991.

Rockville, Maryland : National Institute on Drug Abuse, 1995.

Rockville, Maryland : National Institute on Drug Abuse, 1979.

Springfield, Virginia. : National Technical Information Service, 1984.

Greenwich, Conn. : Jai Press Inc., 1997.

Source: Brazilian Journal of Probability and Statistics, Volume 34, Number 2, 203--203.

Source: Brazilian Journal of Probability and Statistics, Volume 34, Number 1, 1--1.

A guide to the tech gadgets even your hard-to-shop-for friends and family members will love.

You can learn almost anything on YouTube. It is very handy. But navigating through the crud to get to that educational material is a nightmare.

Lineup is subject to change. Please see our masthead for editorial contacts.

Patel was appointed editor of the weekly investigative newspaper in October of 2016.

The Eufy smart scale normally costs $44.99, but Amazon is offering a 40 percent off coupon, which lowers the price to just $26.99.

China should drastically increase its stockpile of nuclear warheads to dissuade the United States from pursuing its strategic ambitions abroad, the editor of the Global Times has urged.
Read Full Article at RT.com

Are they basically the same thing? I am trying to get as much experience with Allegro since a lot of jobs I am looking at right now are asking for Cadence Allegro experience (I wish they asked for Altium experience...). I currently have access to PCB Editor, but I don't want to commit to learning Editor if Allegro is completely different. Also walmart one, are the Cadence Allegro courses worth it? I won't be paying for it and if it's worth it, I figure I might as well use the opportunity to say I know how to use two complex CAD tools.

Hi,

I wanted to find the location of a pin in the design using skill program. pin_dbids = axlDBGetDesign()->pins, this gives me all the dbids of the pins that are present in my design. But when im entering that dbid, pad = axlDBGetPad("000001EA8FD8B9F8" "package geometry/assembly_top" "regular") it is throwing an error stating "This dbid is not user defined. Please enter the user defined". So please provide me a snippet so that I can get the exact pin location in the design using skill script.

FCKEditor version 2.6.8 ASP version suffers from a file upload protection bypass.

Telerik ASP.NET AJAX RadEditor Control versions 2014.1.403.35 and 2009.3.1208.20 suffer from a persistent cross site scripting vulnerability.

The documentary "American Factory" tells us communities need to go beyond the job creation narrative when it comes to attracting foreign investment. 

Attending the Ocean Energy Europe event in Paris recently the considerable presence of developers and manufacturers signalled a long-term transformation for the sector, which - for tidal stream in particular - is now emerging as a technological reality.

In her time at the Mail & Guardian, Patel was responsible for bringing stability to the newsroom and in the process assembled one of the best newsrooms in South Africa.

The post Khadija Patel resigns as Mail & Guardian editor-in-chief appeared first on The Mail & Guardian.

Tell Israelis to enter bomb shelters, they know how. Tell them to stop their car on the side of the road when an air raid siren goes off and to duck into a ditch, they can do it.

Thematic collection: This article is part of the ‘Early Career Researchers’ available at: https://www.lyellcollection.org/cc/SJG-early-career-research

On January 15, 1915, the first issue of PNAS, the official “organ of publication” of the National Academy of Sciences, appeared in print. It was, in some ways, a less than propitious time to launch a journal—just a little more than seven months after the start of what ultimately became...

In our computational study, we use molecular simulations to substantiate a hypothetical mechanism for glycosidic bond cleavage in the presence of a single catalytic acid at the active site of the mutant D10N HiCel45A. In addition to discussing this plausible mechanism from the context of structurally related MltA lytic transglycosylase and subfamily C GH45s, we also suggest the implications of the plausible mechanism for our current understanding of the action of expansins and lytic transglycosylases. As correctly pointed out by Professor Cosgrove (1), there is large body of evidence, a significant portion of which was regrettably not discussed in our paper, that suggests that expansins are incapable of lytic action on polysaccharide substrates. Whereas these insights do not change the results or the conclusions of our article, we would like to thank Professor Cosgrove for these additional insights. In particular, our main point with respect to expansins is that our results suggest the possibility that expansins are capable of nonhydrolytic lytic activity. Our intention was not to suggest this was the mechanism of expansins, but that it should be considered based on our results and the similarity of the active sites.The molecular mechanisms of how expansins enable cell wall expansion remains to be fully understood. Whereas our proposed mechanism resulting in the formation of the 1,6-anhdro product might be found in expansins and might contribute to the mode of action of expansins, we would like to emphasize that the intent of this study was only to suggest this as a...

From their simulations of endoglucanase Cel45A, Bharadwaj et al. (1) propose that structurally related expansins and MltA may cut glycan backbones without generating reducing ends. This is tenable for MltA, a peptidoglycan lytic transglycosylase whose action produces nonreducing 1,6-anhydro products, but is untenable for expansins.Expansins loosen plant cell walls and induce wall expansion. Contrary to the assertion by Bharadwaj et al., the conclusion that expansins are not lytic is not merely based on lack of new reducing ends but is supported by multiple (negative) tests for polysaccharide cleavage that do not rely on detection of reducing ends. At least eight studies with three divergent groups of expansins document this point. For instance, α-expansin did not reduce the viscosity of various wall polysaccharide solutions, an endolytic assay that does not rely on measuring reducing ends (e.g. see Ref. 2 and other studies).Walls treated with α-expansin did not release saccharide fragments, measured by pulsed amperometric detection, which can detect nonreducing saccharides (3).In the case of β-expansins, protein treatments did not cleave the backbones of a wide range of dye-coupled cross-linked wall polysaccharides; nor did they cleave backbones of polysaccharides extracted from plant cell walls, measured by gel permeation chromatography (4).For five microbial expansins, tests with a range of dye-coupled cross-linked polysaccharides likewise did not detect lytic activity (e.g. see Ref. 5). Thus, extensive published evidence argues against lytic action by expansins, as proposed by Bharadwaj (1), and attempts to identify 1,6-anhydro products seem unlikely to succeed.

Clinical and Vaccine Immunology (CVI) will merge with the American Society for Microbiology (ASM) open-access journal mSphere in January 2018. We commemorate this transition by exploring the history of CVI and that of its predecessor, Clinical and Diagnostic Laboratory Immunology (CDLI), and by acknowledging their contributors. Research on vaccines, clinical immunology, and clinical diagnostic immunology published through mSphere will be available without restrictions to an ever-larger audience, which will expedite progress in the field. ASM remains committed to supporting its members and the research community by facilitating the dissemination of scientific knowledge in these important areas.