Antoni Ribas, MD, PhD, and Gillian Leng, MBChB, are featured.

In the plasmaMATCH trial, researchers performed circulating tumor DNA testing on patients with advanced breast cancer and matched those with ESR1, HER2, or AKT1 alterations to targeted therapies. Patients with HER2 and AKT1 mutations experienced response rates greater than 22% with durable benefit.

As COVID-19 continues to surge, cancer scientists engaged in basic research face unique challenges. At centers throughout the United States, investigators are confronting difficult decisions about which experiments to continue, while securing supplies and creating contingency plans for a complete shutdown.

Since 2018, the FDA has required that U.S. clinical trial results be reported to clinicaltrials.gov within a year of trial completion, but this mandate is often ignored. A recent study found that less than half of U.S. trials submitted results to the site by the deadline. Industry-led trials were the most likely to be reported on time.

In a draft guidance, the FDA urges researchers to take steps to increase enrollment of adults age 65 and older in clinical trials of investigational of cancer drugs. Noting that a drug's risk–benefit profile can vary significantly across age groups, the FDA recommends including older adults in early-phase studies and modifying trial designs and recruitment strategies to make it easier for them to participate.

The Foreign Secretary showed some cautious optimism as he revealed the latest data suggested the UK was "starting to win this struggle," three weeks after restrictions were imposed.

Follow our live coronavirus updates HERE Coronavirus: The symptoms

Donald Trump has instructed his administration to temporarily halt funding to the World Health Organisation over its handling of the coronavirus pandemic.

The Government is today set to extend the coronavirus lockdown until at least May 7 amid fresh warnings it is too soon to start easing the restrictions.

The top stories you're waking up to Listen to your Morning Bulletin on Google Assistant and Amazon Alexa smart speakers from 7am every weekday

Donald Trump cut off his daily coronavirus task force briefing without taking any questions from reporters a day after he was slammed for suggesting disinfectant could be injected as a treatment.

Donald Trump skipped the latest White House coronavirus briefing tweeting the event is "not worth the time and effort".

The top stories you're waking up to Listen to your Morning Bulletin on Google Assistant and Amazon Alexa smart speakers from 7am every weekday

Deaf campaigners have begun legal proceedings against the Government over the lack of sign language interpreters during the daily coronavirus briefings.

The top stories you're waking up to Listen to your Morning Bulletin on Google Assistant and Amazon Alexa smart speakers from 7am every weekday

Boris Johnson will today lead the daily Covid-19 briefing for the first time since his return to work following his battle with the virus.

The top stories you're waking up to Listen to your Morning Bulletin on Google Assistant and Amazon Alexa smart speakers from 7am every weekday

The top stories you're waking up to Listen to your Morning Bulletin on Google Assistant and Amazon Alexa smart speakers from 7am every weekday

The top stories you're waking up to Listen to your Morning Bulletin on Google Assistant and Amazon Alexa smart speakers from 7am every weekday

The top stories you're waking up to Listen to your Morning Bulletin on Google Assistant and Amazon Alexa smart speakers from 7am every weekday

Coronavirus: The symptoms

Ontario Premier Doug Ford dropped by his cottage last month, days after asking the province’s residents to stay away from theirs. His office says Ford "drove alone" and was there for less than an hour to check on construction.

And other stories from around the world.

And other stories from around the world

And other stories from around the world

The new group, modelled on the pro-Brexit European Research Group that scrutinised Theresa May's fated Brexit deal, will assess China's handling of the outbreak and broader security concerns.

The couple have been on and off since 2015

Join POLITICO for a series of virtual briefings and audio teleconferences to learn the latest updates on coronavirus and its impacts.

As the televisual equivalent of a mood ring, the White House briefings are extremely useful. As a vehicle for delivering information, not so much.

Trump's decision to air the selectively edited video clips led major US television networks to quickly cut away from his daily coronavirus briefing. 

The story about TV networks cutting away from the US President's press briefing generated the most online discussion with our readers this week.

At the annual invite-only 2020 Enterprise Retreat in Half Moon Bay, CA, 100 enterprise leaders gathered in a social-media free environment, to network, discuss hot topics and dive into provocative, insightful off-the-record 'State of the Union' presentations. This report details their findings.

Keep on reading: The Enterprise 2020 Report: Software CEO Briefing

On Wednesday, October 23, 2019, ACRO hosted a Congressional Briefing on Capitol Hill. With the help of the Congressional Research & Development...

The US District Court in Delaware issued a decision upholding the validity of patent claims from three…

Danish drugmaker Acesion Pharma, which is focused on novel treatments for atrial fibrillation (AF), has…

Germany’s science and technology company Merck KGaA today announced its investment in SynSense (formerly…

GlaxoSmithKline has completed divestment of its Horlicks and other Consumer Healthcare nutrition products…

US pharma major AbbVie has finally completed its $63 billion acquisition of Ireland-incorporated Allergan,…

The Department has filed briefs in three separate cases in Florida, Illinois and New Jersey as part of its continuing effort to enforce civil rights laws that require states to end discrimination against and unnecessary segregation of persons with disabilities.