It is an object of the present invention to apply a sufficient electrical field to a liquid crystal material in a horizontal electrical field liquid crystal display device typified by an FFS type. In a horizontal electrical field liquid crystal display, an electrical field is applied to a liquid crystal material right above a common electrode and a pixel electrode using plural pairs of electrodes rather than one pair of electrodes.

A liquid crystal display device is provided, which includes a thin film transistor including an oxide semiconductor layer, a first electrode layer, a second electrode layer having an opening, a light-transmitting chromatic-color resin layer between the thin film transistor and the second electrode layer, and a liquid crystal layer. One of the first electrode layer and the second electrode layer is a pixel electrode layer which is electrically connected to the thin film transistor, and the other of the first electrode layer and the second electrode layer is a common electrode layer. The light-transmitting chromatic-color resin layer is overlapped with the pixel electrode layer and the oxide semiconductor layer of the thin film transistor.

The present invention relates to the development and manufacturing of viral vaccines. In particular, the invention relates to the field of industrial production of viral vectors and vaccines, more in particular to the use of avian embryonic stem cells, preferably the EBx® cell line derived from chicken embryonic stem cells, for the production of viral vectors and viruses. The invention is particularly useful for the industrial production of viral vaccines to prevent viral infection of humans and animals.

The present invention relates to the generation of a mucin-producing cell using stem/progenitor cells obtained from the amniotic membrane of umbilical cord and therapeutic uses of such mucin-producing cells.

Methods of washing adherent cells, capable of effectively suppressing cell death due to proteolytic enzyme treatment for detaching the adherent cell from a culture vessel and subsequent cell treatment; cell-washing solutions used for the washing method; methods of producing cell suspensions for transplantation using the cell-washing solution; and kits comprising the cell-washing solution. Trehalose or its derivative or a salt thereof is added to physiological aqueous solutions to prepare cell-washing solutions containing trehalose or its derivative or a salt thereof as an active ingredient. The cell-washing solutions can be used to wash adherent cells before detaching the adherent cells from a culture vessel by proteolytic enzyme treatment to suppress cell death due to the proteolytic enzyme treatment. The concentration of trehalose applied to the cell-washing solution may be a concentration capable of suppressing the cell death due to the proteolytic enzyme treatment, such as 0.1 to 20 (w/v) %.

Methods and compositions for targeted delivery of biotherapeutics are provided. The compositions comprise bile-sensitive St. thermophilus bacteria modified to release a biotherapeutic agent following bile exposure. Biotherapeutic agents released by the St. thermophilus bacteria disclosed herein include AQ and AQR rich peptides. Methods of the invention comprise administering to a subject a St. thermophilus bacterium modified to release a biotherapeutic agent following bile exposure. Administration of the St. thermophilus bacterium promotes a desired therapeutic response. The bacterium may be modified to express and release AQ or AQR rich peptides which subsequently inhibit cellular apoptosis or reduce mucosal damage. Thus, methods of the invention find use in treating or preventing a variety of gastrointestinal disorders including C. difficile infection and antibiotic-associated diarrhea.

Management of the health status of an animal colony using a plurality of blood collection cards and the analysis of dried blood from members of the colony that has been collected on the cards. Members of the colony may be removed from the colony as a result of the analysis.

The invention provides an improved design for the construction of extensible nucleic acid-based, ligand-controlled regulatory systems, and the nucleic acid regulatory systems resulting therefrom. The invention contemplates improving the design of the switches (ligand-controlled regulatory systems) through the design of an information transmission domain (ITD). The improved ITD eliminates free-floating ends of the switching and the competing strands, and localizes competitive hybridization events to a contiguous strand of competing and switching strands in a strand-displacement mechanism-based switch, thereby improving the kinetics of strand-displacement. The improved regulatory systems have many uses in various biological systems, including gene expression control or ligand-concentration sensing.

Disclosed are new members of a class of non-lipid small molecule inhibitors which interfere with the interaction between phosphoinositol-3,4,5-triphosphate (PIP3) and pleckstrin homology (PH) domains. These molecules target a broad range of PIP3-dependent signaling events in vitro and exert significant anti-tumor activity in vivo, with improved activity and selectivity toward particular PH domains. The small molecule inhibitors of the invention can be used alone or together with tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) or other cancer medicament to treat cancer. Small molecule inhibitors of the invention act synergistically in combination with TRAIL and with other Akt inhibitors in treating cancer. Pharmaceutical compositions and methods for treating cancer are provided.

The invention is directed to a single-step method for rapidly and efficiently preparing protein-polymer conjugates, including an insulin-polymer conjugate. According to the method of the present invention, a protein and hydrophilic polymer are contacted in the presence of at least one organic solvent and at least one metal chelator, under conditions that promote the formation of a conjugate of the protein and polymer. Thus, the invention is directed to the site-specific modification of selected proteins, such as insulin, with poly(ethylene glycol) at residue PheB1. The invention also provides a pharmaceutical formulation for encapsulating the conjugate in a biodegradable polymer.

Monoclonal antibodies (mAbs) having thyroid stimulating activity (TSAb), especially full or considerably agonistic activity, or thyroid blocking activity (TBAb), which are obtainable by genetic immunization of mice, or fragments (F(ab')2, Fab or Fv) or humanized forms of such monoclonal antibodies or single chain forms (SCA; scFv) of such fragments, which antibodies, or their fragments, compete with bovine TSH for epitopes of the human TSHr, compete with autoantibodies from sera from Graves' patients as well as with autoantibodies from sera from patients harboring blocking autoantibodies for epitopes of the human TSHr, bind to conformational epitopes of the human TSHr located in the first 281 amino acids of the human TSHr, and usually also bind to TSFR receptors (TSHr) from different animals. Various uses of such antibodies, or of peptides corresponding to variable regions of such antibodies, are also described and claimed.

Isolated polynucleotides and polypeptides and recombinant DNA constructs particularly useful for altering agronomic characteristics of plants under nitrogen limiting conditions, compositions (such as plants or seeds) comprising these recombinant DNA constructs, and methods utilizing these recombinant DNA constructs. The recombinant DNA construct comprises a polynucleotide operably linked to a promoter functional in a plant, wherein said polynucleotide encodes an LNT1 polypeptide.

[Problem to be Solved] The importance of sugar chains having α2,3- or α2,6-linked sialic acid at their non-reducing ends is known. Industrial production has been demanded for these sugar chain compounds. Particularly, the production of glycoprotein drugs or the like inevitably requires producing in quantity sugar chains having homogeneous structures by controlling the linking pattern (α2,6-linkage or α2,3-linkage) of sialic acid. Particularly, a triantennary or tetraantennary N-type complex sugar chain having sialic acid at each of all non-reducing ends is generally considered difficult to chemically synthesize. There has been no report disclosing that such a sugar chain was chemically synthesized. Furthermore, these sugar chains are also difficult to efficiently prepare enzymatically.[Solution]The present inventors have newly found the activity of sialyltransferase of degrading sialic acid on a reaction product in the presence of CMP and also found that formed CMP can be degraded enzymatically to thereby efficiently produce a sialic acid-containing sugar chain. The present inventors have further found that even a tetraantennary N-type sugar chain having four α2,6-linked sialic acid molecules, which has previously been difficult to synthesize, can be prepared at high yields by one-pot synthesis comprising the elongation reaction of a biantennary sugar chain used as a starting material without performing purification after each enzymatic reaction.

A chair including a dynamically-flexible back and seat having a shape that adjusts to the movements of a user seated in the chair to enhance user comfort. Each of the back and seat has an air gap formed therewithin and a resilient frame or liner with a spring memory. The resilient liner is adapted to flex in response to compressive forces that are generated as the user slides his body back or from side-to-side in the chair. Accordingly, some of the chair back and some of the chair seat move into respective air gaps so that the shapes of the back and seat change to conform to the movements of the user. The air gaps also establish air flow ventilation channels which run laterally through the back and seat of the chair.

An ergonomic back support device utilizing one or multiple vertical components that include layers (28,36), pressure distributing layers (34,38,50), and a single notched layer (48). These layers provide primary back support located behind and conforming to the Erector spinae muscles (124). The vertical components form an open channel (24) that is parallel to the prime neurological pathway of the spinal column (100). The vertical conforming support components and open channel facilitate physiological functions that promote health. The device accomplishes support without using any transverse, hard or continuous components across or against the back. Other embodiments include the following additional vertical components: a lateral pressure-adjusting device (14), heating layers (40,46), circulation stimulating layers (42,44), and massage layers (52,54). Embodiments include portable and permanently installed versions that can be utilized in the following applications, including, but not limited to, furniture, vehicles, trains, aircraft, boats, ships, and backpacks.

An operating unit (1) for installation in an aircraft cabin comprises an operating unit front side (10) and an operating unit rear side (20), at least one operating element (12, 14) attached in the region of the operating unit front side (10) and accessible to a user, and a holding device (40) for attaching the operating unit (1) to a monument (30) accommodating the operating unit (1) in its state mounted in the aircraft cabin. The holding device (40) is designed to attach the operating unit (1) in its state mounted in the aircraft cabin to the monument (30), in a first position or in a second position, as desired, the operating element (12, 14) in the second position of the operating unit (1) being situated in a spatial position which is lowered with respect to the spatial position of the operating element (12, 14) in the first position of the operating unit (1) and/or is displaced in a direction parallel to an imaginary straight line connecting the operating unit rear side (20) to the operating unit front side (10).

A seating unit that includes a linkage mechanism adapted to move the seating unit between seat-lift, closed, extended, reclined, and seat-lift positions is provided. The linkage mechanism includes a seat-mounting plate mounted to a footrest assembly, a base plate fixedly mounted to a lift assembly, a back-mounting link rotatably coupled to the seat-mounting plate, a seat-adjustment assembly with a bellcrank, and a linear actuator for automating adjustment of the linkage mechanism. In operation, a stroke in a first phase of the linear actuator generates a force on the bellcrank that translates the seat-mounting plate rearward in a consistent angle of inclination and rotates the back-mounting link from a reclined to an upright orientation. A stroke in a second phase acts to collapse the footrest assembly. A stroke in a third phase causes the lift assembly to raise and tilt the seating unit, thereby accommodating egress and ingress of an occupant.

According to an example embodiment, an apparatus is provided that produces a small-step switchable capacitor, which can have steps that are smaller in value than the smallest capacitor used in the system. In one embodiment, an input signal is connected to a switchable capacitor system that includes at least one and/or a plurality of small-step, switchable capacitors. In an example embodiment, a capacitor system may be provided that includes a first capacitance block coupled in series with a second capacitance block. In an example embodiment, the second capacitance block may include one or more switchable capacitors to provide a step in capacitance for the capacitor system between a first setting and a second setting using the one or more switchable capacitors. Also, in an example embodiment, the step in capacitance of the capacitor system may be determined based, at least in part, on a ratio of the capacitance of the second capacitance block to the capacitance of the first capacitance block.

The present invention provides an apparatus for enhancing Q factor of an inductor. The apparatus includes a negative resistance generator coupled to the inductor for providing a negative resistance, and a bias circuit coupled to the negative resistance generator for biasing the negative resistance generator.

A plurality of varactors are coupled via a first electrode to a shared terminal that in turn can operably couple to a source of control voltage. A second electrode for each varactor couples to a corresponding switch, where each switch couples to at least two different voltage levels. So configured, the second electrode of each varactor can be individually connected to either of two voltage levels. This can be leveraged to control, in coarse steps, the overall aggregate effective capacitance presented by these components. At least some of these varactors can have differing corresponding capacitances, the specific values of which can be selected in order to facilitate relatively equal spacing and substantially equal rates of reactance change versus the control voltage value between aggregate-capacitive reactance ranges as correspond to differing settings for the switches at various levels for the control voltage source.

The present invention provides a central frequency adjustment device and adjustable inductor layout; wherein, the central frequency adjustment device is applied in an inductor/capacitor tank (LC tank) for adjusting the central frequency of the LC tank. The device comprises a first inductor with a first end and a second end; a second inductor with one end coupled with the second end of the first inductor; and, a first trimmable wire connected to the first inductor in parallel and to the second inductor in series, which adjusts the central frequency by cutting off the first trimmable wire.

In a signal communication device, a frequency-selective filter has at least one component that is biased by a control signal to establish a center frequency of the frequency-selective filter. A closed-loop bias generator is provided to generate the control signal and to adjust the control signal based, at least in part, on a comparison of the control signal and a reference signal.

One embodiment relates to a circuit for active loss compensation. The circuit includes a parallel inductor-capacitive (LC) tank circuit having a first single-ended output. A first adjustable capacitor, which includes a first terminal and a second terminal, is coupled to the first single-ended output. The circuit also includes a first pair of transistors having sources coupled to a first common node. One transistor of the first pair of transistors has a drain coupled to the first single-ended output and the other transistor of the first pair of transistors has a gate coupled to the second terminal of the first adjustable capacitor. Other embodiments are also disclosed.

Disclosed are one-port and two-port voltage-tunable micro-electromechanical capacitors, switches, and filter devices. High aspect-ratio metal micromachining is used to implement very high quality factor (Q) tunable and fixed capacitors, fixed inductors, and low insertion loss tunable and fixed bandpass LC filters. The tunable capacitors can move in the plane of the substrate by the application of DC voltages and achieve greater than 100% of tuning. A combination of low-loss substrate and highest conductivity metal is used to achieve record high Q and low insertion loss at radio frequencies. The disclosed tunable capacitor structure can also be used as a micromechanical switch.

Aspects and embodiments of the present invention provide a system for obtaining, processing and managing data from an implanted sensor. In some embodiments, a patient or other persons can use a flexible antenna to obtain data from the implanted sensor. The flexible antenna includes at least one transmit loop and at least one receive loop. The transmit loop is adapted to propagate energizing signals to the implanted sensor. The receive loop is adapted to detect a response signal from the implanted sensor. The transmit loop includes a capacitor formed by a discontinuous area. The capacitor is adapted to allow the loop to be tuned. The flexible antenna can communicate with a patient device that collects the data from the implanted sensor, creates a data file and transmits the data file to a remote server over a network. A physician or other authorized person may access the remote server using an access device.

An inductor circuit with high quality (Q) factor includes a primary inductor and a compensation sub-circuit. The compensation sub-circuit is electrically isolated from the primary inductor. The compensation sub-circuit is magnetically coupled with the primary inductor to compensate the loss in the primary inductor.

An electromagnetic system consists of an electric circuit comprising two solenoids wired in series, one mounted either side and proximate to a toroid. Voltage is applied across the toroid and the solenoids in a specific sequence which alters the inductance behavior of the system, resulting in an inductance gain and no mutual inductance between the toroid and the two solenoids.

Control method and apparatus for a manual spray gun may include a second manually actuated trigger disposed on the spray gun handle, with the second trigger being operational to select or change one or more coating operation parameters.

A RFID transponder includes a resonant circuit for providing a clock signal at a predetermined clock frequency, a self-calibration stage for calibrating the resonant circuit's current clock frequency towards the predetermined clock frequency. The self-calibration stage is adapted to compare a first clock frequency of the resonant circuit determined during an interrogation period, during which the resonant circuit is excited by an external RF signal, with a second clock frequency determined during a frequency maintenance period, during which the resonant circuit is excited internally through an oscillation maintenance circuit of the RFID transponder and to calibrate the resonant circuit towards the predetermined clock frequency based on the comparison result.

A circuit (C1-C4) is employed in a TWACS transponder (T) installed in an electric meter (M). The transponder generates inbound signals (IB) transmitted from the location of the electric meter to a central location (R). Firmware (F) within the transponder controls the flow of current for each pulse through the circuit by triggering a semi-conductor device such as a SCR (X1) or TRIAC (X2). The resulting current flow through the inductor for a subsequent pulse, regardless of the pulse's polarity, will be in the opposite direction to that of the previous pulse. The result is to maintain a constant level of magnetization of the inductor core which does not have to be overcome by energy in the subsequent pulse resulting in amplitude of all the pulses imposed on an AC waveform being substantially the same.

An electrical component provides a ceramic element located on or in a dielectric substrate between and in contact with a pair of electrical conductors, wherein the ceramic element includes one or more metal oxides having fluctuations in metal-oxide compositional uniformity less than or equal to 1.5 mol % throughout the ceramic element. A method of fabricating an electrical component, provides or forming a ceramic element between and in contact with a pair of electrical conductors on a substrate including depositing a mixture of metalorganic precursors and causing simultaneous decomposition of the metal oxide precursors to form the ceramic element including one or more metal oxides.

An improved grounding technique for mechanically adjustable rotary capacitors uses a directly grounded bronze sliding contact to effectively and continuously ground the rotating comb-like blades of the capacitor. RF measurements of the continuity and repeatability of the capacitance settings prove the suitability of the modified capacitors for using in pre-calibrated multi-capacitor MHz range impedance tuners.

A method and apparatus for use in a digitally tuning a capacitor in an integrated circuit device is described. A Digitally Tuned Capacitor DTC is described which facilitates digitally controlling capacitance applied between a first and second terminal. In some embodiments, the first terminal comprises an RF+ terminal and the second terminal comprises an RF− terminal. In accordance with some embodiments, the DTCs comprise a plurality of sub-circuits ordered in significance from least significant bit (LSB) to most significant bit (MSB) sub-circuits, wherein the plurality of significant bit sub-circuits are coupled together in parallel, and wherein each sub-circuit has a first node coupled to the first RF terminal, and a second node coupled to the second RF terminal. The DTCs further include an input means for receiving a digital control word, wherein the digital control word comprises bits that are similarly ordered in significance from an LSB to an MSB.

An optical beam scanning apparatus is disclosed, including: a laser source that emits an optical beam, a deflection part that deflects the optical beam, a light receiving part that receives a returning light of the optical beam which is deflected toward the laser source by the deflection part, a signal generation part that generates a synchronization detection signal, and an optical source drive part that conducts a lighting control of the laser source. The light receiving part is arranged in vicinity to the laser source. The signal generation part detects a timing at which the light receiving part receives the returning light, by an output signal from the light receiving part to generate the synchronization detection signal. The optical source drive part conducts the lighting control of the laser source in response to the synchronization detection signal as a reference.

A print shop consolidation system including a print shop consolidation management system with an application is provided. The application is used to (1) evaluate, with a set of information, an operational capacity of a first print shop to process both a first group of print jobs and a second group of print jobs, (2) evaluate, with the set of information, an operational capacity of the second print shop to process both the first and second groups of print jobs, and (3) use the evaluations of (1) and (2) to consolidate processing of the first and second groups of print jobs at one of first and second print shops.

A method enables changes in the operation of a web printing system in response to web dimensional changes being detected. The method includes identifying a cross-process dimensional change in a web moving through a printing system, comparing the identified cross-process dimensional change to a predetermined threshold, and changing operation of a component in the web printing system in response to the cross-process dimensional change exceeding the predetermined threshold.

Currency bills are received, transported, and imaged to produce image data from which a visually readable image of each currency bill can be reproduced. Each of the currency bills includes a denomination, a serial number, and a set of secondary identifiers. One of the currency bills is determined to be a suspect bill. The suspect bill serial number is attempted to be extracted from the image data associated with the suspect bill. In response to failing to extract a complete serial number of the suspect bill, a serial number field in a suspect report is populated with a serial number snippet image.

A combined video display and image capture system and method are disclosed. In one embodiment the system alternates between the capture period of the camera (306) and the image display (302) period to isolate the camera (306) from the display (302). Various methods are disclosed to achieve the alternation in the capture and the display periods of the system. Distortions in the captured image can be corrected using an image correction subsystem.

A liquid crystal display (LCD) device capable of reducing the number of printed circuit boards (PCBs) and the number of signal transmitters, and thus reducing manufacturing costs, is disclosed. The LCD device includes a liquid crystal panel having a display to display an image, a plurality of data drive integrated circuits (ICs) connected between one-side portion of the liquid crystal panel and a source PCB, to drive data lines arranged on the display of the liquid crystal panel, a light source unit to provide light to the liquid crystal panel, and a unified board formed with a light source driver to drive the light source unit, and a drive circuit to drive the data drive ICs.

In one aspect, the present invention is directed to an earthquake detection and alarming apparatus, comprising: a transparent object (46) having a concave surface on the top thereof; a rollable object (34) placed on the concave surface; an apiary of light projectors (30) placed above the concave surface; an apiary of light receivers (38) correspondingly to the apiary of light projectors, the apiary of light receivers being placed below the concave surface; and circuitry for determining: (a) vibrating frequency and amplitude of the rollable object with reference to the concave surface from sensing of the receivers (38); and (b) deducing therefrom the arrival of primary waves.

Systems and methods are provided for installing workflow servers for a print shop. One embodiment is a system that installs a workflow server for a print shop. The system accesses installation templates, configured for different categories of print shop, that describe a set of print shop resources expected to exist at the category of print shop. The system also installs workflow server software on a computer system of a print shop. During the installation, the system determines a category for the print shop, selects an installation template that matches the category of the print shop, and performs a dialogue of queries with a user to determine which resources of the set of print shop resources identified by the installation template are available to the print shop, wherein the dialogue excludes queries for print shop resources that are not in the set of print shop resources described by the installation template.

Next generation pervasive wireless ecosystems and mobile information apparatus are herein disclosed and enabling millions of users to migrate to pervasive digital living and enterprise. Wireless communications may include the mobile information apparatus accessing wireless local area network or by direct wireless communication. The mobile information apparatus may include a wireless unit compatible with Bluetooth and/or IEEE802.11. Mobile information apparatus may conduct a local area wireless search within short distances for discovering wireless devices in its vicinity, receive an attribute related to the discovered wireless device, establish secure wireless communication with the discovered wireless device, and transfer or synchronize digital content or applications to/from the discovered wireless device. The discovered wireless device may be other mobile apparatus, wireless televisions, wireless audio devices, wireless speakers, wireless printers, among others, in a digital living room or office. Mobile apparatus may be smart phones, information pads, or laptops with touch sensitive screen interface.

A printing device includes at least one printing engine that has actuators and sensors. At least one engine controller is operatively connected to the printing engine, the engine controller uses software to control operations of the printing engine. At least one non-volatile memory is operatively connected to the engine controller. The non-volatile memory stores values used by the engine controller to control operations of the printing engine. Further, at least one adapter card is operatively connected to the non-volatile memory and to the actuators and sensors. The adapter card stores data and receives sensor feedback from the sensors. The adapter card uses the data and the sensor feedback to control the actuators by bypassing the engine controller when communicating with the actuators. The adapter card provides adapter card feedback to the non-volatile memory.

According to one embodiment, a liquid crystal display device includes a first substrate including a gate line extending in a first direction, a source line including an oblique line portion extending in a third direction which crosses at an acute angle a second direction perpendicular to the first direction, a pixel electrode including an oblique electrode portion extending in the third direction, and a first alignment film covering the pixel electrode, a second substrate including a counter-electrode which is opposed to the pixel electrode, and a second alignment film covering the counter-electrode, and a liquid crystal layer held between the first substrate and the second substrate. A first rubbing direction of the first alignment film is a direction which crosses the third direction at an acute angle, and an angle formed between the first rubbing direction and the third direction is 3.6° or more.

Provided is a welding metal in which the chemical component composition thereof is appropriately controlled; an A value that is specified by a predetermined relational expression satisfies the requirement of being 3.8% to 9.0%; an X value that is specified by a predetermined relational expression satisfies the requirement of being 0.5% or greater; the area percentage of carbide particles having a circle-equivalent diameter of 0.20 μm or greater in the welding metal is 4.0% or less; and the number of carbide particles having a circle-equivalent diameter of 1.0 μm or greater is 1000 particles/mm2 or less. This welding metal, which can exhibit not only high strength but also good low-temperature toughness and good drop-weight characteristics, is useful as a material for a pressure vessel in a nuclear power plant.

A gamma prime nickel-base superalloy and components formed therefrom that exhibit improved high-temperature dwell capabilities, including creep and hold time fatigue crack growth behavior. A particular example of a component is a powder metallurgy turbine disk of a gas turbine engine. The gamma-prime nickel-base superalloy contains, by weight, 16.0 to 30.0% cobalt, 11.5 to 15.0% chromium, 4.0 to 6.0% tantalum, 2.0 to 4.0% aluminum, 1.5 to 6.0% titanium, up to 5.0% tungsten, 1.0 to 7.0% molybdenum, up to 3.5% niobium, up to 1.0% hafnium, 0.02 to 0.20% carbon, 0.01 to 0.05% boron, 0.02 to 0.10% zirconium, the balance essentially nickel and impurities, wherein the titanium:aluminum weight ratio is 0.5 to 2.0.

A gamma prime nickel-base superalloy and components formed therefrom that exhibit improved high-temperature dwell capabilities, including creep and hold time fatigue crack growth behavior. A particular example of a component is a powder metallurgy turbine disk of a gas turbine engine. The gamma-prime nickel-base superalloy contains, by weight, 18.0 to 30.0% cobalt, 11.4 to 16.0% chromium, up to 6.0% tantalum, 2.5 to 3.5% aluminum, 2.5 to 4.0% titanium, 5.5 to 7.5% molybdenum, up to 2.0% niobium, up to 2.0% hafnium, 0.04 to 0.20% carbon, 0.01 to 0.05% boron, 0.03 to 0.09% zirconium, the balance essentially nickel and impurities, wherein the titanium:aluminum weight ratio is 0.71 to 1.60.

Sliding parts are made of Pb-free Cu—Bi based sintered material. The side in contact with a shaft is machined to a predetermined roughness. A number of Bi phases are present on the finished surface. Stable performance of Bi is to be exhibited. Machined sintered material covers a portion of the Bi phases. The ratio of the exposed surface area of the Bi phases is 0.5% or more relative to the area of the finished surface.

New 6xxx aluminum alloy bodies and methods of producing the same are disclosed. The new 6xxx aluminum alloy bodies may be produced by preparing the aluminum alloy body for post-solutionizing cold work, cold working by at least 25%, and then thermally treating. The new 6xxx aluminum alloy bodies may realize improved strength and other properties.

Disclosed are: a casting aluminum alloy that is excellent in elongation as alternative properties of a high cycle fatigue strength and a thermal fatigue strength and is suitably usable for a casting for which both of the excellent high cycle fatigue strength and the excellent thermal fatigue strength are required, for example, an internal combustion engine cylinder head; a casting made of the aluminum alloy; a manufacturing method of the casting; and further, an internal combustion engine cylinder head composed of the aluminum alloy casting and manufactured by the manufacturing method of the casting. The casting aluminum alloy contains, in terms of mass ratios, 4.0 to 7.0% of Si, 0.5 to 2.0% of Cu, 0.25 to 0.5% of Mg, no more than 0.5% of Fe, no more than 0.5% of Mn, and at least one component selected from the group consisting of Na, Ca and Sr, each mass ratio of which is 0.002 to 0.02%.