cia Beneficial Effect of Low-Glycemic Index Diet in Overweight NIDDM Subjects By care.diabetesjournals.org Published On :: 1992-04-01 Thomas M S WoleverApr 1, 1992; 15:562-564Short Report Full Article
cia Update on Prevention of Cardiovascular Disease in Adults With Type 2 Diabetes Mellitus in Light of Recent Evidence: A Scientific Statement From the American Heart Association and the American Diabetes Association By care.diabetesjournals.org Published On :: 2015-09-01 Caroline S. FoxSep 1, 2015; 38:1777-1803Scientific Statement Full Article
cia Standardizing Clinically Meaningful Outcome Measures Beyond HbA1c for Type 1 Diabetes: A Consensus Report of the American Association of Clinical Endocrinologists, the American Association of Diabetes Educators, the American Diabetes Association, the Endo By care.diabetesjournals.org Published On :: 2017-12-01 Gina AgiostratidouDec 1, 2017; 40:1622-1630Continuous Glucose Monitoring and Risk of Hypoglycemia Full Article
cia Type 1 Diabetes Mellitus and Cardiovascular Disease: A Scientific Statement From the American Heart Association and American Diabetes Association By care.diabetesjournals.org Published On :: 2014-10-01 Sarah D. de FerrantiOct 1, 2014; 37:2843-2863Scientific Statement Full Article
cia Can a Shift in Fuel Energetics Explain the Beneficial Cardiorenal Outcomes in the EMPA-REG OUTCOME Study? A Unifying Hypothesis By care.diabetesjournals.org Published On :: 2016-07-01 Sunder MudaliarJul 1, 2016; 39:1115-1122Diabetes Care Symposium Full Article
cia Staging Presymptomatic Type 1 Diabetes: A Scientific Statement of JDRF, the Endocrine Society, and the American Diabetes Association By care.diabetesjournals.org Published On :: 2015-10-01 Richard A. InselOct 1, 2015; 38:1964-1974Scientific Statement Full Article
cia Psychosocial Care for People With Diabetes: A Position Statement of the American Diabetes Association By care.diabetesjournals.org Published On :: 2016-12-01 Deborah Young-HymanDec 1, 2016; 39:2126-2140Psychosocial Research and Care in Diabetes Full Article
cia Hypoglycemia and Diabetes: A Report of a Workgroup of the American Diabetes Association and The Endocrine Society By care.diabetesjournals.org Published On :: 2013-05-01 Elizabeth R. SeaquistMay 1, 2013; 36:1384-1395Scientific Statement Full Article
cia Digitizing financial services key to Africa's post-pandemic growth, experts say By www.upi.com Published On :: Thu, 07 May 2020 16:18:10 -0400 As the COVID-19 pandemic begins to take root in Africa, experts say that digitizing financial services could help keep the continent safe Full Article
cia Defense officials criticize Ligado's 5G proposal at Senate hearing By www.upi.com Published On :: Wed, 06 May 2020 19:42:44 -0400 Top Pentagon officials told lawmakers Wednesday that a proposed nationwide network to provide 5G and internet-of-things services was "too risky to be worth it." Full Article
cia Type 1 Diabetes Mellitus and Cardiovascular Disease: A Scientific Statement From the American Heart Association and American Diabetes Association By care.diabetesjournals.org Published On :: 2014-10-01 Sarah D. de FerrantiOct 1, 2014; 37:2843-2863Scientific Statement Full Article
cia Staging Presymptomatic Type 1 Diabetes: A Scientific Statement of JDRF, the Endocrine Society, and the American Diabetes Association By care.diabetesjournals.org Published On :: 2015-10-01 Richard A. InselOct 1, 2015; 38:1964-1974Scientific Statement Full Article
cia Psychosocial Care for People With Diabetes: A Position Statement of the American Diabetes Association By care.diabetesjournals.org Published On :: 2016-12-01 Deborah Young-HymanDec 1, 2016; 39:2126-2140Psychosocial Research and Care in Diabetes Full Article
cia 2019 Update to: Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) By care.diabetesjournals.org Published On :: 2020-02-01 John B. BuseFeb 1, 2020; 43:487-493Consensus Report Update Full Article
cia Redefining Hypoglycemia in Clinical Trials: Validation of Definitions Recently Adopted by the American Diabetes Association/European Association for the Study of Diabetes By care.diabetesjournals.org Published On :: 2020-01-20T12:00:30-08:00 OBJECTIVE To determine if the International Hypoglycaemia Study Group (IHSG) level 2 low glucose definition can identify clinically relevant hypoglycemia in clinical trials and offer value as an end point for future trials. RESEARCH DESIGN AND METHODS A post hoc analysis was performed of the SWITCH (SWITCH 1: n = 501, type 1 diabetes; SWITCH 2: n = 721, type 2 diabetes) and DEVOTE (n = 7,637, type 2 diabetes) trials utilizing the IHSG low glucose definitions. Patients in all trials were randomized to either insulin degludec or insulin glargine 100 units/mL. In the main analysis, the following definitions were compared: 1) American Diabetes Association (ADA) 2005 (plasma glucose [PG] confirmed ≤3.9 mmol/L with symptoms); and 2) IHSG level 2 (PG confirmed <3.0 mmol/L, independent of symptoms). RESULTS In SWITCH 2, the estimated rate ratios of hypoglycemic events indicated increasing differences between treatments with decreasing PG levels until 3.0 mmol/L, following which no additional treatment differences were observed. Similar results were observed for the SWITCH 1 trial. In SWITCH 2, the IHSG level 2 definition produced a rate ratio that was lower than the ADA 2005 definition. CONCLUSIONS The IHSG level 2 definition was validated in a series of clinical trials, demonstrating its ability to discriminate between basal insulins. This definition is therefore recommended to be uniformly adopted by regulatory bodies and used in future clinical trials. Full Article
cia Association of Urine Haptoglobin With Risk of All-Cause and Cause-Specific Mortality in Individuals With Type 2 Diabetes: A Transethnic Collaborative Work By care.diabetesjournals.org Published On :: 2020-02-20T11:55:30-08:00 OBJECTIVE Haptoglobin is an acute-phase reactant with pleiotropic functions. We aimed to study whether urine haptoglobin may predict risk of mortality in people with type 2 diabetes. RESEARCH DESIGN AND METHODS We employed a transethnic approach with a cohort of Asian origin (Singapore) (N = 2,061) and a cohort of European origin (France) (N = 1,438) included in the study. We used survival analyses to study the association of urine haptoglobin with risk of all-cause and cause-specific mortality. RESULTS A total of 365 and 525 deaths were registered in the Singapore cohort (median follow-up 7.5 years [interquartile range 3.5–12.8]) and French SURDIAGENE cohort (median follow-up 6.8 years [interquartile range 4.3–10.5], respectively. Singapore participants with urine haptoglobin in quartiles 2 to 4 had higher risk for all-cause mortality compared with quartile 1 (unadjusted hazard ratio [HR] 1.47 [95% CI 1.02–2.11], 2.28 [1.62–3.21], and 4.64 [3.39–6.35], respectively). The association remained significant in quartile 4 after multiple adjustments (1.68 [1.15–2.45]). Similarly, participants in the French cohort with haptoglobin in quartile 4 had significantly higher hazards for all-cause mortality compared with quartile 1 (unadjusted HR 2.67 [2.09–3.42] and adjusted HR 1.49 [1.14–1.96]). In both cohorts, participants in quartile 4 had a higher risk of mortality attributable to cardiovascular disease and infection but not malignant tumor. CONCLUSIONS Urine haptoglobin predicts risk of mortality independent of traditional risk factors, suggesting that it may potentially be a novel biomarker for risk of mortality in patients with type 2 diabetes. Full Article
cia Special Olympics athletes get dental help thanks to ADA member dentist By www.ada.org Published On :: Tue, 21 Jan 2020 11:15:00 -0600 As the world gets ready for the Special Olympics Sweden Invitational Games in February, one of the ADA’s member dentists will be watching as the Special Smiles program he founded will be used to screen and attend to the dental needs of the competing athletes. Full Article
cia Addressing caries through the lens of social justice, health equity, human rights By www.ada.org Published On :: Wed, 29 Jan 2020 11:49:00 -0600 It’s a conviction that was published in the November issue of The Journal of the American Dental Association and the basis for the October 2019 forum that Dr. Francisco Ramos-Gomez fostered, where dentists, physicians, nurses and public health and public policy experts proposed, discussed and recommended solutions for preventing early childhood caries through the lens of social justice, health equity and human rights. Full Article
cia Missouri Dental Association notches win By www.ada.org Published On :: Mon, 03 Feb 2020 12:43:00 -0600 Thanks to the advocacy efforts of the Missouri Dental Association, a managed care organization has agreed to remove an authorization tool it was requiring dentists to use prior to using sedation. Full Article
cia CDC reminds clinicians to use standard precautions, recommends isolating patients with coronavirus symptoms By www.ada.org Published On :: Fri, 07 Feb 2020 13:41:00 -0600 In light of the “emerging, rapidly evolving” outbreak of the novel coronavirus 2019-nCoV, the Centers for Disease Control and Prevention is reminding clinicians to use standard precautions consistently and advising they isolate patients who show signs and symptoms of the virus. Full Article
cia Journal of Public Health Dentistry study finds association between man-made chemical, childhood caries By www.ada.org Published On :: Mon, 10 Feb 2020 16:08:00 -0600 Circulating levels of perfluorodecanoic acid, a type of perfluoroalkyl acid, may be associated with dental caries in children, according to a study published in the fall 2019 issue of the Journal of Public Health Dentistry. Full Article
cia Free ADA webinar to help dentists with social media marketing By www.ada.org Published On :: Wed, 12 Feb 2020 14:01:00 -0600 The ADA is hosting a free webinar in March on how to effectively advertise and market services and dental practices on Facebook and Instagram. Full Article
cia March JADA finds past incarceration associated with oral health issues By www.ada.org Published On :: Mon, 24 Feb 2020 09:00:00 -0600 Formerly incarcerated people in the U.S. have worse oral health outcomes than those who have never been in prison, according to a study published in the March issue of The Journal of the American Dental Association. Full Article
cia Learning, social opportunities abound at ADA FDC 2020 By www.ada.org Published On :: Wed, 26 Feb 2020 14:14:00 -0600 Registration opens April 22 for the ADA FDC Annual Meeting, which will offer a variety of learning and social opportunities for dentists and their teams to enjoy. Full Article
cia American Dental Board of Anesthesiology recognized as national certifying board for dental specialty By www.ada.org Published On :: Wed, 04 Mar 2020 13:15:00 -0600 The National Commission on Recognition of Dental Specialties and Certifying Boards announced March 4 it recognizes the American Dental Board of Anesthesiology as the national certifying board for dental anesthesiology. Full Article
cia Oral medicine recognized as a dental specialty By www.ada.org Published On :: Wed, 04 Mar 2020 14:24:00 -0600 Oral medicine becomes the 11th dental specialty recognized by the National Commission on Recognition of Dental Specialties and Certifying Boards. The recognition comes after the National Commission on March 2 adopted a resolution based on an application from the American Academy of Oral Medicine to recognized oral medicine as a dental specialty. Full Article
cia The decision to specialize By www.ada.org Published On :: Tue, 10 Mar 2020 10:41:00 -0500 The question surfaces at the beginning of dental school, maybe even sooner, when the dream first takes hold. What kind of dentist do I want to be? Do I want to be a general dentist? An oral surgeon? A pediatric dentist? Every student’s path to becoming a dentist is unique. Choosing whether to specialize is no different. Full Article
cia Association launches new ADA Science & Research Institute By www.ada.org Published On :: Thu, 12 Mar 2020 08:07:00 -0500 The American Dental Association launched the new ADA Science & Research Institute LLC on Jan. 1, bringing together the Science Institute in Chicago and research group in Gaithersburg, Maryland, that previously reported to the ADA Foundation. Full Article
cia Association warns members on potential coronavirus-related phishing emails By www.ada.org Published On :: Mon, 16 Mar 2020 16:29:00 -0500 The Association is asking member dentists and their dental teams to increase their vigilance over phishing emails as a result of the coronavirus, known as COVID-19.Attackers often use emergencies as an opportunity to send fake emails tailored to that situation, the association said. Full Article
cia Association provides coronavirus infection control resources for dentists By www.ada.org Published On :: Thu, 19 Mar 2020 09:43:00 -0500 The ADA is sharing with members the CDC guidelines on the use of personal protective equipment on its website dedicated to COVID-19. Full Article
cia Two March 27 webinars focus on surviving financial storm caused by pandemic By www.ada.org Published On :: Thu, 26 Mar 2020 15:52:00 -0500 The ADA is presenting two free webinars March 27, aiming to help dentists financially weather the economic downturn during the COVID-19 outbreak and illustrate how ADA advocacy has helped turn the tide. Full Article
cia Association offers resources on handling stress during a pandemic By www.ada.org Published On :: Thu, 26 Mar 2020 19:16:00 -0500 Noting that we’re living through a time of uncertainty and it’s normal to feel stressed and anxious, the Center for Professional Success today posted free resources on stress management to help dentists navigate this time of uncertainty amid the COVID-19 pandemic. Full Article
cia Delta Dental member companies begin offering financial assistance during pandemic By www.ada.org Published On :: Tue, 31 Mar 2020 13:33:00 -0500 The ADA is calling on third-party payers to support dental practices in the midst of the COVID-19 pandemic. Full Article
cia Code Maintenance Committee approves new codes associated with vaping, teledentistry By www.ada.org Published On :: Thu, 02 Apr 2020 10:27:00 -0500 On the heels of the ADA’s December interim policy on vaping comes a new CDT code that references counseling services about high-risk substance use including vaping. Full Article
cia Oregon Dental Association dentists, volunteers donate PPE to help emergency relief By www.ada.org Published On :: Mon, 20 Apr 2020 10:37:00 -0500 Oregon Dental Association dentists, volunteers donate more than 600,000 pieces of PPE to help emergency relief efforts Full Article
cia American College of Emergency Physicians endorses ADA's antibiotics guideline By www.ada.org Published On :: Wed, 22 Apr 2020 14:18:00 -0500 The American College of Emergency Physicians has endorsed the American Dental Association's clinical practice guideline on the use of antibiotics for the management of pulpal- and periapical-related pain and swelling. Full Article
cia Arizona Dental Association hosts one of the largest virtual dental conferences to date By www.ada.org Published On :: Fri, 24 Apr 2020 14:23:00 -0500 Scottsdale, Ariz. — In February, the Arizona Dental Association was fully prepared to host the Western Regional Dental Experience April 2-4 at the Renaissance Phoenix Glendale Hotel and Spa. Full Article
cia Delta Dental of California, Massachusetts offer financial relief to dentists in midst of COVID-19 pandemic By www.ada.org Published On :: Wed, 29 Apr 2020 14:52:00 -0500 Two additional Delta Dental member companies announced details April 27-28 of programs that will provide economic assistance and post-COVID-19 pandemic relief for members of its independent provider networks across 16 states and the District of Columbia. Full Article
cia Social Innovation for Refugee Inclusion: From Bright Spots to System Change By www.migrationpolicy.org Published On :: Wed, 12 Jun 2019 11:51:08 -0400 In the three years since the European migration and refugee crisis vividly captured public attention, a wave of innovative initiatives has emerged to help newcomers settle into receiving societies. Now, as the sense of crisis abates, this report explores what these initiatives will need to do to outlast the hype and produce lasting change on key integration issues such as housing, economic inclusion, and community building. Full Article
cia Diabetes Is Associated With Worse Long-term Outcomes in Young Adults After Myocardial Infarction: The Partners YOUNG-MI Registry By care.diabetesjournals.org Published On :: 2019-09-23T15:12:23-07:00 OBJECTIVEWe sought to determine the prevalence of diabetes and associated cardiovascular outcomes in a contemporary cohort of young individuals presenting with their first myocardial infarction (MI) at age ≤50 years.RESEARCH DESIGN AND METHODSWe retrospectively analyzed records of patients presenting with a first type 1 MI at age ≤50 years from 2000 to 2016. Diabetes was defined as a hemoglobin A1c ≥6.5% (48 mmol/mol) or a documented diagnosis of or treatment for diabetes. Vital status was ascertained for all patients, and cause of death was adjudicated.RESULTSAmong 2,097 young patients who had a type 1 MI (mean age 44.0 ± 5.1 years, 19.3% female, 73% white), diabetes was present in 416 (20%), of whom 172 (41%) were receiving insulin. Over a median follow-up of 11.2 years (interquartile range 7.3–14.2 years), diabetes was associated with a higher all-cause mortality (hazard ratio 2.30; P < 0.001) and cardiovascular mortality (2.68; P < 0.001). These associations persisted after adjusting for baseline covariates (all-cause mortality: 1.65; P = 0.008; cardiovascular mortality: 2.10; P = 0.004).CONCLUSIONSDiabetes was present in 20% of patients who presented with their first MI at age ≤50 years and was associated with worse long-term all-cause and cardiovascular mortality. These findings highlight the need for implementing more-aggressive therapies aimed at preventing future adverse cardiovascular events in this population. Full Article
cia The Association of Lipoprotein(a) Plasma Levels With Prevalence of Cardiovascular Disease and Metabolic Control Status in Patients With Type 1 Diabetes By care.diabetesjournals.org Published On :: 2020-02-04T06:30:22-08:00 OBJECTIVETo investigate the association of the cardiovascular risk factor lipoprotein (Lp)(a) and vascular complications in patients with type 1 diabetes.RESEARCH DESIGN AND METHODSPatients with type 1 diabetes receiving regular care were recruited in this observational cross-sectional study and divided into four groups according to their Lp(a) levels in nmol/L (very low <10, low 10–30, intermediate 30–120, high >120). Prevalence of vascular complications was compared between the groups. In addition, the association between metabolic control, measured as HbA1c, and Lp(a) was studied.RESULTSThe patients (n = 1,860) had a median age of 48 years, diabetes duration of 25 years, and HbA1c of 7.8% (61 mmol/mol). The median Lp(a) was 19 (interquartile range 10–71) nmol/L. No significant differences between men and women were observed, but Lp(a) levels increased with increasing age. Patients in the high Lp(a) group had higher prevalence of complications than patients in the very low Lp(a) group. The age- and smoking-status–adjusted relative risk ratio of having any macrovascular disease was 1.51 (95% CI 1.01–2.28, P = 0.048); coronary heart disease, 1.70 (95% CI 0.97–3.00, P = 0.063); albuminuria, 1.68 (95% CI 1.12–2.50, P = 0.01); and calcified aortic valve disease, 2.03 (95% CI 1.03–4.03; P = 0.042). Patients with good metabolic control, HbA1c <6.9% (<52 mmol/mol), had significantly lower Lp(a) levels than patients with poorer metabolic control, HbA1c >6.9% (>52 mmol/mol).CONCLUSIONSLp(a) is a significant risk factor for macrovascular disease, albuminuria, and calcified aortic valve disease in patients with type 1 diabetes. Poor metabolic control in patients with type 1 diabetes is associated with increased Lp(a) levels. Full Article
cia Commercially Available Insulin Products Demonstrate Stability Throughout the Cold Supply Chain Across the U.S. By care.diabetesjournals.org Published On :: 2020-04-27T16:36:14-07:00 OBJECTIVEA recent publication questioned the integrity of insulin purchased from U.S. retail pharmacies. We sought to independently validate the method used, isotope dilution solid-phase extraction (SPE) liquid chromatography mass spectrometry (LC-MS), and expand analysis to two U.S. Pharmacopeia (USP) methods (high-performance LC with ultraviolet detection and LC-MS).RESEARCH DESIGN AND METHODSEach method was used to evaluate nine insulin formulations, purchased at four pharmacies, within five geographic locations in the U.S.RESULTSAll human and analog insulins measured by the USP methods (n = 174) contained the expected quantity of active insulin (100 ± 5 units/mL). When using isotope dilution SPE-LC-MS, units-per-milliliter values were well below product labeling due to unequal recovery of the internal standard compared with target insulin.CONCLUSIONSInsulin purchased from U.S. pharmacies is consistent with product labeling. Full Article
cia Acrylamide Exposure and Oxidative DNA Damage, Lipid Peroxidation, and Fasting Plasma Glucose Alteration: Association and Mediation Analyses in Chinese Urban Adults By care.diabetesjournals.org Published On :: 2020-04-28T14:58:19-07:00 OBJECTIVEAcrylamide exposure from daily-consumed food has raised global concern. We aimed to assess the exposure-response relationships of internal acrylamide exposure with oxidative DNA damage, lipid peroxidation, and fasting plasma glucose (FPG) alteration and investigate the mediating role of oxidative DNA damage and lipid peroxidation in the association of internal acrylamide exposure with FPG.RESEARCH DESIGN AND METHODSFPG and urinary biomarkers of oxidative DNA damage (8-hydroxy-deoxyguanosine [8-OHdG]), lipid peroxidation (8-iso-prostaglandin-F2α [8-iso-PGF2α]), and acrylamide exposure (N-acetyl-S-[2-carbamoylethyl]-l-cysteine [AAMA], N-acetyl-S-[2-carbamoyl-2-hydroxyethyl]-l-cysteine [GAMA]) were measured for 3,270 general adults from the Wuhan-Zhuhai cohort. The associations of urinary acrylamide metabolites with 8-OHdG, 8-iso-PGF2α, and FPG were assessed by linear mixed models. The mediating roles of 8-OHdG and 8-iso-PGF2α were evaluated by mediation analysis.RESULTSWe found significant linear positive dose-response relationships of urinary acrylamide metabolites with 8-OHdG, 8-iso-PGF2α, and FPG (except GAMA with FPG) and 8-iso-PGF2α with FPG. Each 1-unit increase in log-transformed level of AAMA, AAMA + GAMA (UAAM), or 8-iso-PGF2α was associated with a 0.17, 0.15, or 0.23 mmol/L increase in FPG, respectively (P and/or P trend < 0.05). Each 1% increase in AAMA, GAMA, or UAAM was associated with a 0.19%, 0.27%, or 0.22% increase in 8-OHdG, respectively, and a 0.40%, 0.48%, or 0.44% increase in 8-iso-PGF2α, respectively (P and P trend < 0.05). Increased 8-iso-PGF2α rather than 8-OHdG significantly mediated 64.29% and 76.92% of the AAMA- and UAAM-associated FPG increases, respectively.CONCLUSIONSExposure of the general adult population to acrylamide was associated with FPG elevation, oxidative DNA damage, and lipid peroxidation, which in turn partly mediated acrylamide-associated FPG elevation. Full Article
cia The Association of Energy and Macronutrient Intake at Dinner Versus Breakfast With Disease-Specific and All-Cause Mortality Among People With Diabetes: The U.S. National Health and Nutrition Examination Survey, 2003-2014 By care.diabetesjournals.org Published On :: 2020-04-30T07:25:50-07:00 OBJECTIVEThis study aims to evaluate the association of energy and macronutrient intake at dinner versus breakfast with disease-specific and all-cause mortality in people with diabetes.RESEARCH DESIGN AND METHODSA total of 4,699 people with diabetes who enrolled in the National Health and Nutrition Examination Survey from 2003 to 2014 were recruited for this study. Energy and macronutrient intake was measured by a 24-h dietary recall. The differences () in energy and macronutrient intake between dinner and breakfast ( = dinner – breakfast) were categorized into quintiles. Death information was obtained from the National Death Index until 2015. Cox proportional hazards regression models were developed to evaluate the survival relationship between and diabetes, cardiovascular disease (CVD), and all-cause mortality.RESULTSAmong the 4,699 participants, 913 deaths, including 269 deaths due to diabetes and 314 deaths due to CVD, were documented. After adjustment for potential confounders, compared with participants in the lowest quintile of in terms of total energy and protein, participants in the highest quintile were more likely to die due to diabetes (hazard ratio [HR]energy 1.92, 99% CI 1.08–3.42; HRprotein 1.92, 99% CI 1.06–3.49) and CVD (HRenergy 1.69, 99% CI 1.02–2.80; HRprotein 1.96, 99% CI 1.14–3.39). The highest quintile of total fat was related to CVD mortality (HR 1.67, 99% CI 1.01–2.76). Isocalorically replacing 5% of total energy at dinner with breakfast was associated with 4% and 5% lower risk of diabetes (HR 0.96, 95% CI 0.94–0.98) and CVD (HR 0.95, 95% CI 0.93–0.97) mortality, respectively.CONCLUSIONSHigher intake of energy, total fat, and protein from dinner than breakfast was associated with greater diabetes, CVD, and all-cause mortality in people with diabetes. Full Article
cia Circulating Retinol-Binding Protein 4 Is Inversely Associated With Pancreatic {beta}-Cell Function Across the Spectrum of Glycemia By care.diabetesjournals.org Published On :: 2020-05-07T08:41:18-07:00 OBJECTIVEThe aim of this study was to examine the association of circulating retinol-binding protein 4 (RBP4) levels with β-cell function across the spectrum of glucose tolerance from normal to overt type 2 diabetes.RESEARCH DESIGN AND METHODSA total of 291 subjects aged 35–60 years with normal glucose tolerance (NGT), newly diagnosed impaired fasting glucose or glucose tolerance (IFG/IGT), or type 2 diabetes were screened by a standard 2-h oral glucose tolerance test (OGTT) with the use of traditional measures to evaluate β-cell function. From these participants, 74 subjects were recruited for an oral minimal model test, and β-cell function was assessed with model-derived indices. Circulating RBP4 levels were measured by a commercially available ELISA kit.RESULTSCirculating RBP4 levels were significantly and inversely correlated with β-cell function indicated by the Stumvoll first-phase and second-phase insulin secretion indices, but not with HOMA of β-cell function, calculated from the 2-h OGTT in 291 subjects across the spectrum of glycemia. The inverse association was also observed in subjects involved in the oral minimal model test with β-cell function assessed by both direct measures and model-derived measures, after adjustment for potential confounders. Moreover, RBP4 emerged as an independent factor of the disposition index-total insulin secretion.CONCLUSIONSCirculating RBP4 levels are inversely and independently correlated with β-cell function across the spectrum of glycemia, providing another possible explanation of the linkage between RBP4 and the pathogenesis of type 2 diabetes. Full Article
cia Angela's Tips for Handling Your Child's Special Education Needs By schoolpsychologistfiles.blogspot.com Published On :: Fri, 08 Jan 2010 01:22:00 +0000 This guest post is written by Angela Peterson who writes on the topic of Online Psychology Degrees and can be emailed at angela_peterson@rediffmail.comIt’s not easy raising a child, and when he or she is affected by a severe disorder or disease, you have a greater challenge ahead of you. You have to put in extra effort, energy and thought into your child’s development and progress, one aspect of which includes their education. Some parents of children with special needs may be tempted to overprotect by keeping them in cloistered environments and limiting their interaction with the outside world. This usually only hampers the child instead of helping them. If you’re a parent with a child who has special needs, here’s some strategies: * Understand your child: Some children may be able to express themselves while others are limited because of their disability. Whatever the case, understand your child and know that they have a mind of their own even if they are unable to speak it. Instead of forcing your will on them, get to know what they wish to do and cater to their needs as much as possible as long as it does not cause them any harm. * Be patient: It’s a tough task, but you need to have an enormous amount of patience with your child. You need to condition yourself to be patient through practice and experience, otherwise you and your child will be subject to a great deal of stress. * Decide on their education: There are many options for providing education to your special needs child, so look for what is available in your area. If you plan to homeschool, you will need to do some research before you’re up to the task. Many feel that it’s better to let the professionals handle this task who are trained and more experienced. Also, your child gets to mingle with other children and interact with them on a regular basis, which is very important to his or her social development. *Think about inclusive classrooms: Parents often want their special needs children to attend regular schools. Learn about inclusive classrooms and determine if it is a good fit for your child. Consider if your child is up to the task of being educated with general education children and if he/she can cope with the curriculum in such classrooms. Although teachers in inclusive classrooms are trained to deal with children with special needs, there may be times when your child could be bullied or teased by the other kids for not being like them. Take all these facts into consideration before you decide on an inclusive classroom for your child.Children with special needs need all the help and support they can get from parents and teachers, and it’s up to you to decide on the best form of education for them. Full Article
cia How Much of Your Child's Special Education Meeting Did You Understand? By schoolpsychologistfiles.blogspot.com Published On :: Tue, 28 Dec 2010 14:43:00 +0000 As a School Psychologist- I attend numerous Special Education Meetings weekly. There are Child Study Meetings, where we discuss interventions and may decide to complete an evaluation. There are eligibility meetings, where we determine if a student is eligible for special education services. There are IEP meetings where we develop a plan for a student who is eligible for special education. Additionally, there are Manifestation Determination meetings, Functional Behavioral Assessments, Behavior Intervention Plans, and 504 Meetings. I may attend around 5-10 meetings a week and I only work part time. Special education teachers, administrators, and a few others will attend these meetings as well. We are VERY used to the process and the terminology. That being said, we constantly have to remind ourselves that parents are often not used to any of it. We went to school for years to learn this, and we've been living it out in our careers. It's second nature to many of us. Parents often come in understanding very little. I try to be conscious of explaining what we are doing to the parents. However, it's a lot of information that gets thrown out very quickly. I want to know how many of the readers feel that you understood what transpired in the meetings you attended? Did you feel rushed? Did you feel supported? Share your comments and please vote in the poll. I'll leave it open through January and then discuss the results. Full Article
cia What Parents Need to Know About the Special Education Evaluation By schoolpsychologistfiles.blogspot.com Published On :: Sat, 22 Sep 2012 17:36:00 +0000 I spend most days of my life working with various students who are at different parts in the sped referral process. I attend Child Study Meetings where we decide if we are going to evaluate a student. I observe and screen children and talk with parents and teachers to help the committee make a good decision about whether we should do a special education evaluation. I evaluate those students (this includes Psychological testing, observations, talking with student/teacher/parent, doing rating scales, etc.). I attend eligibility meetings where we determine if the student is eligible for for special education services. All of this is second nature to me and sometimes I need to stop and remember when a parent comes in, that this is NEW. When I talk to parents, I find that many parents do not fully understand the special education referral process, even when they nod and act like they do. We as school staff need to do a better job of helping the parents understand the process. Parents also need to speak up and ask questions when there is not understanding. This is a guide for parents to understand the process of special education testing, the testing components, and some of the test data. It is important to note that schools systems and states will vary to some degree. If you have any questions about the process in your school system, ask your school psychologist, teacher, or principal. Parents have every right to ask questions and usually school personnel are happy to help make this process less anxiety-provoking for you. It is important for parents to understand their rights during the special education process.Special Education ProcessAfter data shows that interventions have been attempted and if a student is suspected of having a disability, a referral is made to evaluate him or her for special education testing. Once the parents sign the Permission for Testing Forms, timelines begin and the schools have 65 business days to complete the assessments and hold the eligibility meeting. Some states may have a different timeline. During these 65 days, several testing components will be completed with you and your child. The evaluators will write reports and a copy will be given to parents at the eligibility meeting. However, schools are required to have a copy available for parents to pick up two days before the eligibility meeting. It is advised, that parents take advantage of this and read reports before the meeting to help get familiar with the information and to formulate questions. The reports hold a lot of information that can be overwhelming if you are not familiar with this type of testing. Read Understanding Test Scores to understand the types of tests used and what the scores mean.Additionally, the meeting is likely to bring forth strong emotions as your child’s difficulties are discussed openly. It can be overwhelming for parents, especially when not prepared. When parents do not read the reports prior to the eligibility meeting, they are the only people at the table who come to the meeting not knowing what to expect.What if My Child is Found ELIGIBLE for Special Education Services?Once a child is eligible for special education services, the schools have 30 days to develop an Individualized Education Plan (IEP) for the student. This will consist of accommodations, goals, and describe the services offered. Parents are part of a committee to help create this document. Once it is signed, schools are legally required to follow it. It is reviewed once a year, unless parents or teachers feel that changes are necessary. Every three years, the committee will determine if the student should be reevaluated. This is called a triennial evaluation. Sometimes another full evaluation will be conducted, other times a review of records and updated teacher information is used.What if My Child is Found INELIGIBLE for Special Education Services?If your child was found ineligible for special education services and you agree with the eligibility findings, then your child will not receive special education. He or she was evaluated because of a problem that still needs to be addressed within regular education. Ask for a separate meeting with your teacher or a team to determine what accommodations or strategies can be used to help.If you believe that your child requires special education services and has a disability, but was found ineligible for services, make an appointment to meet with the special education director. If an agreement cannot be reached, you may be able to have an Independent Evaluation at the expense of the school. The results of that testing will be brought back to an eligibility meeting. A child MUST have 2 things before they can receive special education services: They must have a disability and there must be a documented educational impact that the student requires special education services to be successful. Full Article
cia Check out this Awesome Special Education Infographic by USC Rossier By schoolpsychologistfiles.blogspot.com Published On :: Sun, 21 Oct 2012 17:56:00 +0000 USC Rossier Online Full Article
cia Artificial tongue with gold taste buds to test maple syrup By www.upi.com Published On :: Tue, 05 May 2020 13:34:08 -0400 Scientists in Quebec have developed an artificial tongue that can taste the flavor profiles of maple syrup, researchers revealed in a paper published on Tuesday. Full Article