SuperSport United winger Aubrey Modiba says a conversation with club CEO Stanley Matthews convinced him to stay despite interest from Mamelodi Sundowns.

Williams driver George Russell is enjoying sim racing online while Formula 1 is suspended but admits he doesn't get the same sense of speed or fear.

Mercedes' Lewis Hamilton has said that holding races without any fans will feel "even worse than a test day".

Borussia Dortmund star Erling Braut Haaland has been backed to sign for Liverpool in the future, while Manchester United have been criticised for missing out on him.

Former captain Paul O'Connell says it will be vital for the British & Irish Lions to pick a leader capable of beating the Springboks at their own game.

With the UK government set to tighten its lockdown restrictions, fresh doubts have been cast over the viability of a British Grand Prix.

Former New Zealand head coach and current England defence chief John Mitchell believes some good may come for rugby union from the coronavirus.

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School, friends and normal day to day interactions have taken a virtual shift. However, for those with limited access to the internet, devices and other technology, isolation can be challenging.

8 November 2013

Research Event

Event participants

Jeremy Gordon, Director, China Business Services
Chair: Roderic Wye, Associate Fellow, Asia Programme, Chatham House

China's National Health Commission reported 14 new confirmed coronavirus cases on May 9, the highest number since April 28, including the first for more than a month in the city of Wuhan where the outbreak was first detected late last year. While China had officially designated all areas of the country as low-risk last Thursday, the new cases according to data published on Sunday represent a jump from the single case reported for the day before. The new Wuhan case, the first reported in the epicentre of China's outbreak since April 3, was previously asymptomatic, according to the health commission.

Shelling of Tripoli's Mitiga airport early on Saturday, part of an intensified barrage of artillery fire on the capital in recent days, hit fuel tanks and damaged passenger planes, the Transport Ministry said in a statement. Mitiga is the last functioning airport in the Libyan capital, though civilian flights stopped in March because of repeated shelling even before the country imposed a lockdown over the coronavirus pandemic. Brega Petroleum Marketing Company, part of the National Oil Corporation, said its jet fuel tanks at Mitiga caught fire after coming under attack and firemen were working to control the blaze.

Travel blogger and photographer Andy Luten drove 4,200 miles across six states to see the grounded jets, detailing the shocking state of aviation.

Multidrug resistance (MDR) in cancer arises from cross-resistance to structurally- and functionally-divergent chemotherapeutic drugs. In particular, MDR is characterized by increased expression and activity of ATP-binding cassette (ABC) superfamily transporters. Sphingolipids are substrates of ABC proteins in cell signaling, membrane biosynthesis, and inflammation, for example, and their products can favor cancer progression. Glucosylceramide (GlcCer) is a ubiquitous glycosphingolipid (GSL) generated by glucosylceramide synthase, a key regulatory enzyme encoded by the UDP-glucose ceramide glucosyltransferase (UGCG) gene. Stressed cells increase de novo biosynthesis of ceramides, which return to sub-toxic levels after UGCG mediates incorporation into GlcCer. Given that cancer cells seem to mobilize UGCG and have increased GSL content for ceramide clearance, which ultimately contributes to chemotherapy failure, here we investigated how inhibition of GSL biosynthesis affects the MDR phenotype of chronic myeloid leukemias. We found that MDR is associated with higher UGCG expression and with a complex GSL profile. UGCG inhibition with the ceramide analog d-threo-1-(3,4,-ethylenedioxy)phenyl-2-palmitoylamino-3-pyrrolidino-1-propanol (EtDO-P4) greatly reduced GSL and monosialotetrahexosylganglioside levels, and co-treatment with standard chemotherapeutics sensitized cells to mitochondrial membrane potential loss and apoptosis. ABC subfamily B member 1 (ABCB1) expression was reduced, and ABCC-mediated efflux activity was modulated by competition with nonglycosylated ceramides. Consistently, inhibition of ABCC-mediated transport reduced the efflux of exogenous C6-ceramide. Overall, UGCG inhibition impaired the malignant glycophenotype of MDR leukemias, which typically overcomes drug resistance through distinct mechanisms. This work sheds light on the involvement of GSL in chemotherapy failure, and its findings suggest that targeted GSL modulation could help manage MDR leukemias.

The EU-U.S. relationship is one of the most significant partnerships among wealthy nations. Interconnections between the two on migration issues make dialogue necessary and inevitable, as each relies on each other to attain a number of policy objectives, most clearly in the case of travel and border security.

This final report summarizes and reflects upon the key findings of the Improving EU and U.S. Immigration Systems: Learning from Experience comparative research project undertaken by MPI and the European University Institute through a grant from the European Commission.

While many Red Stripe Premier League (RSPL) players are finding it very difficult to stay motivated and maintain their training regime until the league is able to restart, Portmore defender Romaine Breakenridge remains highly motivated and eager...

A Manchester corporal is now on sick leave after receiving several blows to his face allegedly by a woman police inspector at work yesterday. It is reported that the incident happened in the guard room of the Mandeville Police Station.

As daunting as this COVID-19 pandemic has proven to be, and as devastating as its impact is on people both here at home and around the world, we must stand together, united. We must all act with purpose, resolve, love and compassion because when we...

Brutal. Horrific. Tragic. Choose your ­description. The April jobs report showed, in harrowing ­detail, just how terribly the coronavirus outbreak has pummelled the United States economy. Most obviously, there’s the 14.7 per cent unemployment rate...

The operator Jamaica’s two largest airports wants to scrap or delay non-essential capital projects. It forms part of a wider halt of capital projects by the Grupo Aeroportuario del Pacífico – which translate to Pacific Airport Group, or GAP –...

Education officials across the Caribbean and Latin America have asserted that teachers will be in need of psycho-social support for their return to the classroom, following the COVID-19 pandemic. Approximately 91,710 teachers and seven million...

This book explores how developing-country governments have institutionalized ties with emigrants and their descendents. It offers an unprecedented taxonomy of 45 diaspora-engaging institutions found in 30 developing countries, exploring their activities and objectives. It also provides important practitioner insights from Mali, Mexico, and the Philippines.

This edited volume examines the development impact of diasporas in six critical areas: entrepreneurship, capital markets, "nostalgia" trade and "heritage" tourism, philanthropy, volunteerism, and advocacy.

Este manual ofrece a los formuladores de políticas y especialistas una guía accesible y práctica sobre las iniciativas gubernamentales referentes a la diáspora. Este manual contiene un menú, seleccionado cuidadosamente, de opciones normativas y programáticas viables basadas en experiencias reales en distintas partes del mundo.

Ce manuel pratique et simple d’utilisation à l’usage des décideurs et des praticiens fait le point des mesures les plus récentes prises par les pouvoirs publics en direction des diasporas. La question qui se pose aux responsables politiques n’est pas tant de savoir si les diasporas peuvent être utiles à leur pays d’origine, mais comment elles le sont et quels types de politiques et de programmes publics sont à même de favoriser ces relations.

This practical handbook highlights policies and programs that can magnify the resources, both human and financial, that emigrants and their descendants contribute to development. It gives concrete examples of policies and programs that have been effective, and pulls out both useful lessons and common challenges associated with the topics at hand.

This edited volume develops a pragmatic approach to the engagement of highly skilled members of the diaspora for the benefit of their countries of origin. The book, edited by a World Bank senior economist, is based on empirical work in middle-income and high-income economies.

I am a dog sitter for my sister, she pays me around $100 a week. I also do extra chores around the house such as cleaning as an exchange for not paying rent. The money she pays me is usually transferred through zelle or paid cash. Im not sure if I would be considered an independent contractor or an employee. Also does she have to report to the irs my income and what forms would she have to use? Ive always received w2s from employers, so I’m Clueless to what I should do this tax season.  Thank you in advance!  Sorry I forgot to mention that my income for this last year was approximately $5000

Sweden’s strong economic record continues to be marred by its struggles to integrate immigrants, especially those who come through humanitarian or family channels. This report describes how Sweden is trying to overcome these labor market integration challenges and analyzes how successful its workforce development and integration policies have been in helping immigrants progress from low-skilled work to middle-skilled jobs.

This report presents an overview of Czech integration policies, with a special focus on economic integration. It focuses on policies designed to support migrants’ incorporation in the Czech labor market, and assesses the extent to which these policies facilitate migrants’ upward mobility into more skilled work.

Immigrants in the United Kingdom find work easily thanks to a flexible labor market, but often have trouble moving up the ladder into middle-skilled work. This report examines how workforce and integration policies affect immigrant workers in the United Kingdom.

Despite a robust mainstream workforce development system offering job-search and other employment assistance to newcomers, immigrants in France are more likely to be unemployed or in low-skilled work than their native-born peers. This report examines how well recent changes to integration policy, in combination with mainstream employment policies, are supporting migrants' integration and advancement in the labor market.

Part of a series exploring issues likely to be addressed by the new National Integration Plan, this webinar, with perspectives from MPI, the National Partnership for New Americans, and the National Skills Coalition, looks at the role of adult education and English language and skills training in the immigrant integration process.

Part of a series exploring recommendations likely to be addressed by the new National Integration Plan, this webinar, with perspectives from MPI, the WE Global Network, and Lutheran Immigrant and Refugee Services, examines the role of economic development initiatives and refugee resettlement programs/infrastructure in immigrant integration. 

Part of a series exploring issues likely to be addressed by the new National Integration Plan, this webinar, with perspectives from the cities of New York and Seattle and others delves into possible recommendations on federal coordination of local government immigrant integration initiatives, including language access.