Thompson, Katrina Daly, 1975-

American Water Works Association

This cohort study compares the characteristics and management of acute heart failure in global regions comprising 44 countries.

This study develops and validates a quantitative method to predict the pulmonary to systemic flow ratio in patients with congenital heart disease from chest radiographs using deep learning.

This cohort study assesses whether long-term variability and rate of change of blood pressure from young adulthood to midlife are associated with cardiovascular disease and all-cause mortality by middle age.

Increased attention has focused on shared decision-making (SDM) and use of decision aids for treatment decisions in cardiology. In this issue of JAMA Cardiology, Coylewright et al report the results of a rigorously performed pilot study on the use of a decision aid to facilitate SDM for patients with symptomatic severe aortic stenosis (AS) at high or prohibitive risk for surgery considered for transcatheter aortic valve replacement vs medical therapy. Comparisons were made between encounters before clinicians were trained to use a decision aid and the first and fifth encounters after a decision aid was used. The patient-clinician interactions were audio recorded and later coded by independent reviewers using a validated measure to assess SDM. This mixed-methods study found that SDM significantly improved in a stepwise manner from the initial usual care encounter (before use of a decision aid) to the first and then fifth encounters after implementation of the decision aid. Along with this improvement in SDM, patients (n = 35) demonstrated increased knowledge about their treatment choices and reported increased satisfaction in their care with no increase in decisional conflict. In contrast, clinicians (n = 6) reported that they believed they already engaged in SDM prior to use of the decision aid and, after multiple uses of the decision aid, believed patients did not understand or benefit from this tool. The disconnect between clinician and patient perspectives was sobering and has implications for the adoption of decision aids or other tools to facilitate SDM in the clinical setting. Notable limitations of the study, which are acknowledged by the authors, include (1) small sample size (of clinicians and patients); (2) the decision aid is most useful for the relatively smaller number of patients at high or prohibitive risk for surgery for whom transcatheter aortic valve replacement and medical therapy may both be reasonable options; and (3) the lack of diversity in the clinicians (all male), which reflects the current demographics of interventional cardiology and cardiac surgery.

This mixed-methods pilot study examines whether the repeated use of a decision aid by heart teams was associated with greater shared decision-making, along with improved patient-centered outcomes and clinicians’ attitudes about decision aids.

This study developed and validated a prognostic prediction model for patients with heart failure.

This cross-sectional study investigates whether hospital inpatient percutaneous coronary intervention volume is associated with rates of 30-day risk-adjusted mortality and hospital readmission after transcatheter aortic valve replacement and transcatheter mitral valve repair.

Lowering low-density lipoprotein cholesterol (LDL-C) levels remains a mainstay of cardiovascular disease prevention, but gaps in treatment remain, even in persons with hypercholesterolemia and greatly elevated LDL-C levels. Although well-described gene variants in the apolipoprotein B (APOB), low-density lipoprotein receptor (LDLR), and proprotein convertase subtilisin/kexin type 9 (PCSK9) genes explain small but important fractions of monogenic hypercholesterolemia, recent attention has turned to prognostication of cardiovascular disease using polygenic risk scores (PRS) that incorporate common genetic variants derived from large-scale genome-wide association studies of lipid subfractions. Earlier PRS considered only variants with genome-wide significance, and newer studies have focused on methods that better capture the variance conferred by millions of variants, suggesting an ability to identify risk equivalent to monogenic mutations. There remains a gap in evidence from prospective observational studies or treatment trials regarding the appropriate placement of PRS in risk assessment and lipid treatment decisions relative to information on rare monogenic gene variants, particularly in multiethnic populations.

Secondary mitral regurgitation (MR) has long been recognized as prognostically important. Even mild MR is associated with adverse outcomes. Yet, surgical trials have not shown improved survival with invasive therapy whereas medical therapy and cardiac resynchronization therapy are associated with improved outcomes. The 2018 publication of the Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients with Functional Mitral Regurgitation (COAPT) and Multicentre Study of Percutaneous Mitral Valve Repair MitraClip Device in Patients With Severe Secondary Mitral Regurgitation (MITRA-FR) trials and their apparently discordant results have focused attention on the differences in trial design as well as patient populations.

This Special Communication proposes a classification of patients with left-ventricular disease according to the severity of mitral regurgitation that is proportionate vs disproportionate to left-ventricular end-diastolic volume.

Robert Evett (1922-1975) was a composer, arts editor, and critic who made his home primarily in the Washington, D.C., area. This collection contains several scores, sketches, and instrument parts for works composed by Evett; biographical information collected by Evett's family after his death; and his published book and music reviews for the "Atlantic Monthly," "New Republic," and "Washington...

Lawyer, educator, and judge. Personal and official correspondence, lectures, legal briefs and opinions, legal case files, memoranda, speeches, writings, research notes, and other papers documenting Bork's career as a lawyer, legal scholar, professor of law, and federal appellate court judge. Also included is material relating to his unsuccessful nomination to the Supreme Court.

Associate justice of the United States Supreme Court. Correspondence and telegrams, some written while Lurton was attending the University of Chicago (1857-1886) and while he was a prisoner in Camp Chase, Ohio, and at Johnson Island Prison during the Civil War.

Hayden Library - PQ7082.P7 C23 2018

The disappearance of inflammatory communal slogans from political speeches suggests development is the agenda for 2014.

Stefanakis, Alexandros, 1982-

Acha, Eduardo Marcelo

Australia. Bureau of Meteorology

O'Toole, Peter Martin, author

Hogarth, Peter J

Castro, Peter, author

Jacobson, Susan Kay, author

Davis, John K., author

Murray-Darling Basin Authority (Australia), author, issuing body

Schwartz, Judith D., author

Hansen, Shirley J., 1928- author

Martin, Sarah, author

Bertness, Mark D., 1949-

Nielsen, Larry A., 1948- author