Coronavirus disease 2019 (Covid-19) is highly contagious with limited treatment options. Early and accurate diagnosis of Covid-19 is crucial in reducing the spread of the disease and its accompanied mortality. Currently, detection by reverse transcriptase polymerase chain reaction (RT-PCR) is the gold standard of outpatient and inpatient detection of Covid-19. RT-PCR is a rapid method, however, its accuracy in detection is only ~70-75%. Another approved strategy is computed tomography (CT) imaging. CT imaging has a much higher sensitivity of ~80-98%, but similar accuracy of 70%. To enhance the accuracy of CT imaging detection, we developed an open-source set of algorithms called CovidCTNet that successfully differentiates Covid-19 from community-acquired pneumonia (CAP) and other lung diseases. CovidCTNet increases the accuracy of CT imaging detection to 90% compared to radiologists (70%). The model is designed to work with heterogeneous and small sample sizes independent of the CT imaging hardware. In order to facilitate the detection of Covid-19 globally and assist radiologists and physicians in the screening process, we are releasing all algorithms and parametric details in an open-source format. Open-source sharing of our CovidCTNet enables developers to rapidly improve and optimize services, while preserving user privacy and data ownership.

It’s that time of the year again. A new TV season is upon us. With some shows beginning to air this week, I thought it best to post my “to watch” schedule for the fall. Unlike last year, I…

It has been a whirlwind of a year. Looking back at where I ended 2018 and started 2019, I was not fully prepared for everything that happened. The big items from 2019 were: Yours truly turned 35. Shut down the business side of Theme…

Coronavirus Family Tree The University of Washington Virology lab, which is testing samples for coronavirus, tweeted last night.…

After Governor Jay Inslee announced a prohibition on gatherings of 250 people or more in three Washington counties (Snohomish, King, Pierce) on Wednesday, and with public health concerns growing over the COVID-19 pandemic, many organizations in Spokane are following suit. The Inlander will be frequently updating its online calendar of events to reflect local cancelations as we hear of them.…

We at the Inlander are committed to keeping people informed and connected throughout the coronavirus outbreak. We'll continue to update this page with the latest headlines.…

Sam Mendes' 1917, which took Best Picture and Best Director awards at the Golden Globes earlier this week, looks like a standard period piece.…

Jenny Don't and the Spurs were right in the middle of recording their third full-length album when a vocal polyp put a halt to the process.…

Calling all fearless freaks! Mark your calendars: The Flaming Lips have rescheduled their now-canceled April gig at the Fox Theater for March 19, 2021.…

ON INLANDER.COM WORLD: Roughly two weeks after Canada's deadliest mass shooting, Prime Minister Justin Trudeau introduced an immediate ban on what he called “military-style assault weapons.”…

ON INLANDER.COM NATION: Even as U.S. President Donald Trump urges states to reopen their economies, his own administration projects that the death toll from COVID-19 will spike to 3,000 people per day.…

At every level of America's food system, mandated closures and outbreaks of COVID-19 have interrupted the finely tuned network that normally gets food from farmers and food processors to restaurants, grocery stores and food banks.…

If you go to check how many people are hospitalized with COVID-19 in Spokane, the Spokane County Regional Health District website will give you an answer. Right now, it lists eight people as currently hospitalized with COVID-19, and that number has been trending downward.…

Q: I recently read that a combination of the drugs hydroxychloroquine and azithromycin might be effective against COVID-19. I have diabetes and I am at risk for this viral infection.…

Disclosed are methods of purifying (20R) and (20S) analogs of 2-methylene-19-nor-22-dimethyl-1α,25-dihydroxyvitamin D3 to obtain the (20R) and (20S) analogs in crystalline form. The method includes the steps of preparing a solvent of either diethyl ether or a mixture of 2-propanol and hexane, dissolving a product containing the (20R) and (20S) analog to be purified in the solvent, cooling the solvent and dissolved product below ambient temperature for a sufficient amount of time to form a precipitate of crystals, and recovering the crystals.

Disclosed are methods of purifying the compound (20R)-2-methylene-19-nor-24-difluoro-1α,25-dihydroxyvitamin D3 to obtain the compound in crystalline form. The methods typically include the steps of dissolving a product containing the compound in a solvent comprising hexane and 2-propanol, cooling the solvent and dissolved product below ambient temperature for a sufficient amount of time to form a precipitate of crystals, and recovering the crystals.

This invention discloses N-cyclopropyl-(20R)-2-methylene-19,26,27-trinor-25-aza-vitamin D analogs, and specifically N-cyclopropyl-(20R)-2-methylene-19,26,27-trinor-25-aza-1α-hydroxyvitamin D3 and pharmaceutical uses therefor. This compound exhibits relatively high binding activity and pronounced activity in arresting the proliferation of undifferentiated cells and inducing their differentiation to the monocyte thus evidencing use as an anti-cancer agent especially for the treatment or prevention of leukemia, colon cancer, breast cancer, skin cancer or prostate cancer.

This invention discloses 3-desoxy-2-methylene-19-nor-vitamin D analogs, and specifically (20S)-3-desoxy-2-methylene-1α,25-dihydroxy-19-nor-vitamin D3 and (20R)-3-desoxy-2-methylene-1α,25-dihydroxy-19-nor-vitamin D3 as well as pharmaceutical uses therefor. These compounds exhibit relatively high binding activity and pronounced activity in arresting the proliferation of undifferentiated cells and inducing their differentiation to monocytes thus evidencing use as anti-cancer agents especially for the treatment or prevention of osteosarcoma, leukemia, colon cancer, breast cancer, skin cancer or prostate cancer. These compounds also exhibit relatively high calcemic activity evidencing use in the treatment of bone diseases.

Disclosed are methods of purifying the compound (20R)-19-nor-24-difluoro-1α,25-dihydroxyvitamin D3 to obtain the compound in crystalline form. The methods typically include the steps of dissolving a product containing the compound in a solvent comprising hexane and 2-propanol, cooling the solvent and dissolved product below ambient temperature for a sufficient amount of time to form a precipitate of crystals, and recovering the crystals.

The present invention relates to the use of the miRNA expression profile, particularly of miR-199a-5p, and the target genes regulated thereby for the diagnosis, prognosis and use of miR-199a-5p inhibitors for treating fibroproliferative disorders.

This month alone, Oakland-based, family-owned Mr. Espresso has already donated over 2,500 pounds of coffee to COVID-19 relief efforts all over the Bay Area.

During the first two weeks of April, the 42-year-old company — founded in Alameda by enterprising Italian-born Carlo Di Ruocco and now renowned as the first and currently only outfit in the nation that uses oak wood to roast its beans — has given coffee to the Alameda County Community Food Bank and San Francisco-Marin Food Bank, Frontline Foods, East Bay FeedER, Clinica de La Raza, St. Anthony’s Dining Room, Loaves and Fishes Family Kitchen, and other food-, health-, homeless-, youth-, and family-assistance programs.…

Weeks have passed, and DJs the world over have settled into the reality of sheltering in place. As efforts to combat COVID-19 push on, the masses are staying at home. Clubs have shuttered their doors, bars and restaurants are no more, and non-essential businesses are closed. But in this primetime of social distancing, there has […]

The post Streaming L(o)ive In The Time of COVID-19: What’s the future for DJ live streaming? appeared first on DJ TechTools.

Coming on the heels of the AB5 trauma, the coronavirus lockdown poses an extra economic threat. The COVID-19 pandemic has affected all facets of life in California and the world.…

News you don't want to miss for April 7:

1. A nursing home in Orinda is being hit hard by a covid-19 outbreak that has infected 49 people, including 27 residents and 22 staff members, the East Bay Times reports.…

News you don't want to miss for April 9:

1. Six residents at a nursing home in Hayward have died from covid-19, the East Bay Times reports.…

News you don't want to miss for Easter Weekend:

Oakland will temporarily close 74 miles of city streets to automobile traffic in an effort to give ample space for pedestrians, bike riders, and runners during the covid-19 shelter in place, The Guardian reports.…

News you don't want to miss for April 13:

1. "If the country’s most popular coronavirus model proves accurate, California will reach the peak of its outbreak this Wednesday," the San Francisco Chronicle reports, when it will reach a predicted 66 deaths.…

News you don't want to miss for April 14:

1. Six of the 15 confirmed covid-19 cases at Santa Rita Jail have recovered, the East Bay Times reports.…

News you don't want to miss for April 15:

1. The number of covid-19 deaths in Alameda County increased from 23 to 36 over a two-day period, SFGate reports.…

News you don't want to miss for April 20:

1. Fifty-one employees at Safeway's distribution warehouse in Tracy have been infected with covid-19, including one death, the San Francisco Chronicle reports.…

News you don't want to miss for April 21:

1. Those who suffer the effects of poor air quality are at greater risk of complications associated with the coronavirus, the San Francisco Chronicle reports.…

News you don't want to miss for April 24:

1. San Francisco Mayor London Breed provided a hint on Friday that the city's shelter in place order will be extended past May 4, possibly weeks or a month, KPIX reports.…

News you don't want to miss for April 30:

1. The five fired Oakland police officers involved in the shooting of Joshua Pawlik in 2018 were reinstated after it was found the Oakland Police Commission violated the Brown Act, the state law for transparency in public meetings, KPIX reports.…

News you don't want to miss for May 1:

1. Oakland's lawsuit against the Raiders and the NFL over the team's relocation to Las Vegas was dismissed by a federal court judge on Thursday, according to Bleacher Report.…

It's 40 years today since Southampton FC began their memorable journey to glory in the 1976 FA Cup - and we've got some never before seen photos.

Lyndhurst & Ashurst Cricket Club has reinstated an annual fixture – more than 100 years after it was last played.

ONLY one game was played in the Wessex League on October 24, 1998 – the appalling weather made sure of that.

THEY raced over obstacle courses, juggled about on drum races, strenuously made stakes, mended punctures and rode a furious musical chairs on motorcycles.

ALTHOUGH the city of Southampton emerged as winners of the Hampshire and Isle of Wight games on July 8, 1979, it was the district of the New Forest East who took the glory.

THESE pictures were snapped at a football tournament in Millbrook on November 7, 1999.

ROLAND Tilley pedalled his way to victory in the senior race of the Crabwood CC’s East Street Centre series around Hoglands Park, Southampton.

A LADIES’ night of food and fashion raised £700 for a cancer charity.

STOKE Park Infant School was built in 1988/89 to replace the Victorian building which became an infant school in 1958.

HE may have made his first on-screen appearance more than ninety years ago, but in 1989 he showed his happy face at Marks and Spencer, Southampton.

THE annual event was one which saw local residents flock to the streets to catch a glimpse of the colourful and humerous floats as they trundled down the road.

A NUMBER of schools are closing across Hampshire amid the coronavirus outbreak.

THE Hoegh Osaka will return to Southampton's port today for the first time since becoming stranded in the Solent for 19 days.

List of runners numbered 0002 to 1,999

List of runners numbered 0002 to 1,999