The present invention relates to an in vitro method of diagnosing chronic myelomonocytic leukemia (CMML) in a subject, said method comprising the steps of: a) Detecting a monocyte population in a biological sample from said subject; b) Quantifying the CD14+/CD16− monocytes in said biological sample; c) Comparing the value of step b) to a reference value; and d) Diagnosing CMML based on said comparison. Preferably, said detecting step a) is performed by an exclusion gating strategy by flow cytometry.

The present invention provides detection methods for detecting a pre-cancerous epithelial cell signature. The present invention further provides reagents for use in the detection methods. A subject detection method is useful in various imaging, diagnostic, prognostic, and patient monitoring methods, which are also provided.

A system and method for detecting a biomarker in exhaled breath condensate nanodroplets comprises noninvasively collecting exhaled breath condensate nanodroplets of a subject, and analyzing said nanodroplets utilizing immuno-quantitative polymerase chain reaction to detect one or more target biomarkers.

The present invention relates to methods of determining if a subject has an increased risk of suffering from memory impairment. The methods comprise analyzing at least one sample from the subject to determine a value of the subject's exosomal profile or combined biomarker profile (lipids plus exosomal cargo) and comparing the value of the subject's exosomal or combined biomarker profile with the value of a normal exosomal or biomarker profile, respectively. A change in the value of the subject's exosomal or combined biomarker profile, including a change in the subject's exosomal or combined biomarker profile, over normal values is indicative that the subject has an increased risk of suffering from memory impairment compared to a normal individual.

A population of bright and stable nanocrystals is provided. The nanocrystals include a semiconductor core and a thick semiconductor shell and can exhibit high extinction coefficients, high quantum yields, and limited or no detectable blinking.

Oakland's alaMar Kitchen & Bar is about to start serving 1,500 free meals per week to restaurant workers who have been displaced and derailed by the coronavirus outbreak.

Located at 100 Grand Ave., chef Nelson German's popular seafood restaurant has just issued this announcement:

"We are here for you, Oakland! ...…

Off the Grid will stage a two-part free-meal giveaway today, April 8, from 12 noon to 1 p.m. at Nob Hill Foods Alameda and from 2:30 p.m. to 3:30 p.m. at Pak 'N Save Emeryville.

It's part of the Grocery Employees Meal Fund, which OTG recently launched to help creators feed grocery-store employees and their family members throughout the Covd-19 crisis.…

Oakland-based food-and-drinks company Purity Organic announced today that it is launching a limited new line of Sweet Leaf beverages that consumers can buy directly online.

"We can't wait to get Sweet Leaf back into the hands of our customers online," said Purity Organic vice president of marketing Bill Porter.…

East Bay resident Miles Woodruff, CEO of the pioneering vegan-seafood brand Sophie's Kitchen, has just donated 3,000 cases of plant-based Toona to the Food Bank of Contra Costa and Solano County as well as several other Bay Area food shelters.

Amidst the Covid-19 outbreak, the company's brand-new Lemon Grass Toona flavor has not yet arrived in grocery stores — but 100 percent of it is now being provided to people in need.…

Just in time to celebrate its ten-year anniversary, popular Filipino-fusion food truck Señor Sisig has established a long-term location in Oakland.

The brand-new spot is at 3331 Fruitvale Ave. in the Dimond District.…

People for the Ethical Treatment of Animals sent UC Berkeley chancellor Carol Christ a letter today requesting permission to place a banner on the university's famous clocktower that reads "It's High Time We Went Vegan. PETA."…

The brick-and-mortar Fruitvale location of La Guerrera's Kitchen is now closed — permanently.

Mother-and-daughter owners Ofelia Barajas and Reyna Maldonado decided against negotiating a new lease for the restaurant when their previous one ended in March, as reported by the San Francisco Chronicle.

Instead, the pair will sell tamales online with pickups several days a week at the Ale Industries brewery.…

Benchmark Pizzeria in Old Oakland has closed permanently.

A notice now posted at the restaurant's website, addressed "to our Friends, Regulars, and Supporters," reads:

"We have made the very tough decision to close Benchmark Oakland permanently.…

Now through May 5, healthcare workers and first responders can collect free "Thank You Meals" at any McDonald's location nationwide.

The promotion began on April 22.…

Celebrated chef-restaurateur Kyle Itani, who helms both Itani Ramen and Hopscotch Restaurant & Bar in Uptown Oakland, has just launched a brand-new project: a takeout sushi spot.

Operating out of Itani Ramen and serving its fare via pickup and delivery, Nikkei Sushi will be open Wednesday through Sunday, 2 p.m. - 8 p.m. during its soft opening with hours extending in the future.…

Celebrated chef-restaurateur Kyle Itani, who helms Itani Ramen and Hopscotch Restaurant & Bar in Uptown Oakland, has just launched a brand-new project: a takeout sushi spot.

Here's a leaked track from Oakland vocalist Karyn Paige.

Stories you shouldn’t miss:

1. Alameda County Public Health Director Muntu Davis contends that gentrification should be examined in terms of health impacts because of the displacement and stress it causes for low-income residents, the Bay Area News Group$ reports.…

If you happen to run into any medical residents anytime soon, they may look a little fatigued and broke, especially if they happen to be residents or pediatricians of UCSF Benioff Children’s Hospital of Oakland. Today, the CIR/SEIU Healthcare union that represents resident physicians and pediatricians said it plans to rally in front of the hospital on Friday at 12:15 p.m. along with nurses and community leaders to demand better wagers and working conditions.…

The city's 911 system can leave callers waiting for more than 120 seconds before an operator ever answers. Seconds of delay in an emergency can lead to death. As a result, 911 calls are supposed to be answered quickly.…

A rework grid array interposer with direct power is described. The interposer has a foundation layer mountable between a motherboard and a package. A heater is embedded in the foundation layer to provide local heat to reflow solder to enable at least one of attachment or detachment of the package. A connector is mounted on the foundation layer and coupled to the heater and to the package to provide a connection path directly with the power supply and not via the motherboard. One type of interposer interfaces with a package having a solderable extension. Another interposer has a plurality of heater zones embedded in the foundation layer.

A ground fault circuit interrupter (GFCI) breaker testing system can include an enclosure having at least one wall that forms a cavity. The system can also include at least one GFCI breaker disposed within the cavity. The system can further include a sensing circuit assembly having at least one switch, where the at least one switch is electrically coupled to the at least one GFCI breaker. The system can also include a user interface assembly disposed, at least in part, outside the cavity, where the user interface assembly is coupled to the sensing circuit assembly, where the user interface assembly instructs the at least one switch to test the at least one GFCI breaker.

A package includes a conductive pad, with a plurality of openings penetrating through the conductive pad. A dielectric layer encircles the conductive pad. The dielectric layer has portions filling the plurality of openings. An Under-Bump Metallurgy (UBM) includes a via portion extending into the dielectric layer to contact the conductive pad. A solder region is overlying and contacting the UBM. An integrated passive device is bonded to the UBM through the solder region.

The present invention is to provide a chassis switch, which comprises a chassis for accommodating a designated number of line cards therein; a backplane installed on the back side of the chassis and having a plurality of connectors disposed thereon; at least one line card plugged into one of the connectors corresponding thereto via a front side of the chassis and each having an access switch chip adapted to switch local network signals and an interconnect switch chip adapted to switch the signals between ports of the at least one line card; and a loop adapted to connect the corresponding ports of the access switch chip and the interconnect switch chip respectively through the connectors, so as to enable each line card plugged into the chassis switch to perform a local network switching function and a switching function between the at least one line card.

Examples of a thermal management unit and an electronic apparatus utilizing the thermal management unit are described. In one aspect, the thermal management unit includes a heat sink. The heat sink includes a base portion, a first protrusion structure and a second protrusion structure. The base portion has a first side and a second side opposite the first side. The first protrusion structure protrudes from the first side of the base portion, and includes multiple fins. The second protrusion structure protrudes from the second side of the base portion, and includes multiple ribs. The heat sink may be made of silicon.

News, arts, and dining coverage for Oakland, Berkeley, and the greater East Bay.

I was wondering why the iconic Civic Centre clock in Southampton is not lit up blue on Thursday at 8pm to clap for the NHS.

75 YEARS AGO this week St John Ambulance volunteers played a vital role delivering first aid and providing support to both the public and the armed forces on VE Day.

I SHOULD like to pay tribute to Alan Wiltshire the Echo and Romsey Advertiser reporter whose death was sadly announced last week

I say to all communities pat yourselves on the back for the great job you are doing taking care of each other and supporting each other.

As we predicted earlier this year, a new Rekordbox version has been released. Rekordbox 6 has a new functionality, Cloud Library Sync, which allows the ability to upload tracks and playlists to Dropbox and sync them across multiple devices. Cloud Library Sync: Tracks, playlists, and track metadata are able to be synced across four different […]

The post Rekordbox 6: Now With Cloud Library Syncing appeared first on DJ TechTools.

On Facebook, live streaming just got taken things a step further: with monetization. Many suspected monetizing virtual events was coming, and it seems to be rapidly arriving on the largest social network. Facebook has come forward with new updates to assert its dominance in this COVID-19 era of online entertainment and relationships. New Facebook Tools […]

The post Facebook Now Lets You Charge Entry To Livestream Events appeared first on DJ TechTools.

If you haven’t looked at Traktor DJ, Native Instruments’ iOS app (it runs on Mac and PC too) recently, a new update and the concurrent global stay-home happening seems like the perfect time to do it. The update to Traktor DJ 2.4 has a bunch of features that look like they’re straight out of a […]

The post Traktor DJ 2.4: Transport Control UI Improvements, Genre Sorting appeared first on DJ TechTools.

The Town’s soccer franchise returns to the pitch this weekend with a new head coach and other fresh faces, kicking off its second season in front of Oakland's loud, loyal fans at Laney College. Last year, professional soccer planted seeds in Oakland. This year, fans hope to see them bloom into something beautiful, preferably with lots of wins on the Laney College pitch.…

A reading list specifically appropriate to these trying times. Okay, you're stuck in the house, but is it really that awful? OK, probably.…

Be extra kind to kind people. ARIES (March 21-April 19): Your oracle comes from Aries poet Octavio Paz: "The path the ancestors cleared is overgrown, unused. The other path, smooth and broad, is crowded with travelers.…

ARIES March 21-April 19 “If all the world’s a stage, where the hell is the teleprompter?” asks aphorist Sami Feiring. In my astrological opinion, you Aries are the least likely of all the signs to identify with that perspective.…

ARIES (March 21-April 19) In the future, when the coronavirus crisis has a diminished power to disrupt our lives, I would love for you to have more of the money you need to finance interesting new experiences that help you learn and thrive.…

The present disclosure provides a method for packaging an organic light-emitting diode (OLED) display panel. The method includes providing a first substrate and a second substrate; forming a first bonding layer in a packaging region of the first substrate; and forming a second bonding layer in a packaging region of the second substrate. The method also includes bonding the first substrate with the second substrate by molecular bonding between the first bonding layer and the second bonding layer.

The invention relates to a storage tank (1) in a motor vehicle for receiving an aqueous urea solution for the SCR of nitrogen oxide in the exhaust gas. The storage tank (1) comprises a tank body which forms a storage volume (2) for the urea solution. The storage tank (1) furthermore comprises a filling pipe for filling the storage volume (2) and means for venting the storage volume (2) during the refuelling, wherein the filling pipe (3) has a filling head (9) at a remote end, and the filling head (9) forms an orifice stub (10). The orifice stub (10) defines an orifice (11) for receiving a fuel pump nozzle. Said orifice stub furthermore has an external thread for receiving a complementary union thread of a refuelling cylinder for refuelling by the gas displacement method. The orifice stub forms at least one secondary air opening when the refuelling cylinder is attached, and therefore, when a refuelling cylinder is attached, a sealing seat is bridged by the refuelling cylinder and refuelling by the gas displacement method is possible even if counterflow venting through the filling tube (3) does not take place.

A gas turbine engine cooling system includes a gas turbine engine. The gas turbine engine includes a core engine, a cold sink, a core undercowl space, and a core cowl at least partially surrounding the core engine and defining a radially outer wall of the core undercowl space. The gas turbine engine cooling system includes an undercowl component positioned in the core undercowl space. The gas turbine engine cooling system also includes a heat pipe including a first end, a second end, and a conduit extending therebetween. The first end is thermally coupled to the undercowl component, and the second end is thermally coupled to the cold sink. The heat pipe facilitates transfer of a quantity of heat from the undercowl component to the cold sink.

A hydraulic system for a work machine includes a first control valve including a first direction switch to switch a direction in which the operation fluid is to flow through a first hydraulic actuator and a pressure compensator to maintain a differential pressure to a constant pressure, the differential pressure being a difference between a pressure of the operation fluid to be inputted to the pressure compensator and a pressure of the operation fluid to be outputted from the pressure compensator. And, the hydraulic system includes a second control valve including a second direction switch to switch a direction in which the operation fluid is to flow through a second hydraulic actuator and a flow rate prioritizer to prioritize a flow rate of the operation fluid to be outputted to the second hydraulic actuator.

An electro-hydraulic actuation system includes a regeneration valve in fluid communication with a first fluid chamber and a second fluid chamber of a hydraulic actuator, and a dump valve is in fluid communication with the second fluid chamber and a fluid reservoir. A pump provides a flow of fluid to the first and second fluid chambers, a displacement of the pump controlling a velocity of the actuator during motion in the retraction and extension directions. An electric motor drives the pump, and a controller controls a state of the regeneration valve and the dump valve. At least one feedback device senses a system condition and provides a respective feedback signal indicative of the sensed system condition to the controller, the controller responsive to the feedback signal to determine an occurrence of an over-center load condition and control a state of the regeneration valve and the dump valve in response to the occurrence to maintain the velocity of the actuator.

An injection assembly for a combustor of a gas turbine has an outer body provided with inlet passages for comburent air, a conical tubular portion housed inside the outer body and delimiting partly an inner duct and an outer annular duct; a first and a second supply means for supplying a liquid fuel into the inner duct and, respectively, into the outer annular duct; at least one circumferential annular seat formed being carried by one of the tubular portion and the outer body, so as to collect a mass of liquid fuel advancing in the outer annular duct and make uniform the flow of liquid flowing out of the circumferential annular seat.

Provided are a substrate chuck and a substrate bonding system including the substrate chuck. The substrate bonding system includes a lower substrate chuck and an upper substrate chuck disposed on the lower substrate chuck. The lower substrate chuck has a non-flat lower substrate contact surface, and the upper substrate chuck has a flat upper substrate contact surface.

There are provided an adhesive for a solar-cell back sheet having an excellent curing rate and being capable of exhibiting excellent adhesive performance by short-term aging, and also a polyol composition used for the adhesive, a solar-cell back sheet using the adhesive, and a solar-cell module using the sheet. The adhesive for a solar-cell back sheet contains, as essential components, at least one hydroxyl group-containing resin (A) selected from a polyester polyurethane polyol (A1), a polyester polyol (A2), a hydroxyl group-containing (meth)acrylic resin (A3), and a hydroxyl group-containing fluorocarbon resin (A4), a polyisocyanate (B), and a cyclic amide compound (C).

The invention relates to compositions comprising composite materials comprised of discontinuous fibers and one or more polymers and/or oligomers. The invention relates to methods of making the same. The composite materials can be in the form of compositions, composite sheets, laminates, pellets, and/or shaped composite products.

A method for making a composite structure with a surfacing film thereon. The surfacing film is co-cured with fiber-reinforced resin composite materials. The surfacing film is formed from a curable resin composition containing an epoxy novolac resin, a tri-functional or tetra-functional epoxy resin, ceramic microspheres, an amine-based curing agent, particulate inorganic fillers; and a toughening component. The surfacing film exhibits high Tg and high cross-linked density after curing, as well as high resistance to paint stripper solutions.

The present invention relates to novel thermoplastic polyurethane (TPU) compositions that contain linear monohydric alcohols. The present invention provides for TPU compositions which may be applied at relatively low temperatures, but upon activation (e.g., activation by ultraviolet light), exhibits higher temperature and melt resistance.

The disclosed composite wood particulate products, adhesives contained in such wood particulate products, and methods of making the adhesive and the wood particulate products employ an aldehyde-free adhesive, and more specifically a formaldehyde-free adhesive. The aldehyde-free adhesive includes an inert additive that extends a resin, such as an isocyanate resin, and forms an evenly dispersed, less expensive polymeric adhesive admixture. The extender-filler of the resin is mixed with water to form a slurry. The slurry can then be mixed with a resin, like the isocyanate resin, to form the adhesive. Various rheology modifiers can be added, if desired, to the extender-filler or the slurry. The adhesive can be blended with wood particles to form a mat that is then pressed into a composite wood particulate product.