ge An SDS-PAGE based method for the quantification of carbon black in biological samples By feeds.rsc.org Published On :: Analyst, 2020, 145,3370-3375DOI: 10.1039/D0AN00046A, PaperKeyang Liu, Bin WanQuantification of Carbon Black (CB) in bio-samples was made available through SDS-PAGE gel electrophoresis.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ge The fingerprint of essential bio-oils by Fourier transform ion cyclotron resonance mass spectrometry By feeds.rsc.org Published On :: Analyst, 2020, 145,3414-3423DOI: 10.1039/C9AN02492A, PaperClaudia X. Ramírez, Diana Catalina Palacio Lozano, Hugh E. Jones, Rafael Cabanzo Hernández, Mark P. Barrow, Enrique Mejia-OspinoSix essential oils were analyzed by Fourier transform ion cyclotron resonance mass spectrometry coupled to negative electrospray ionization (ESI(–)/FT-ICR MS).The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ge Removing interference-based effects from infrared spectra – interference fringes re-revisited By feeds.rsc.org Published On :: Analyst, 2020, 145,3385-3394DOI: 10.1039/D0AN00062K, PaperThomas G. Mayerhöfer, Susanne Pahlow, Uwe Hübner, Jürgen PoppSubstantial refractive index mismatches between substrate and layers lead to undulating baselines and changes of band intensity, shape and position. For proper spectrum interpretation, all of these effects must be removed.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ge Selective ratiometric red-emission detection of In3+ in aqueous solutions and in live cells using a fluorescent peptidyl probe and metal chelating agent By feeds.rsc.org Published On :: Analyst, 2020, Advance ArticleDOI: 10.1039/D0AN00288G, PaperJoohee Park, Hyeongseok Yu, See-Hyoung Park, Keun-Hyeung LeeA ratiometric fluorescent detection method for In3+ in aqueous buffered solution, ground water, and live cells was developed.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ge FRET based fluorescent ratiometric probes for rapid detection of endogenous hydrogen sulphide in living cells By feeds.rsc.org Published On :: Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00531B, PaperYuming Zhang, Yuncong Chen, Bai Yang, Xueling Xue, Weijiang He, Zijian GuoReal time monitor of hydrogen sulphide (H2S) level change is of crucial importance for the study of its complicated roles in physiology. Herein, we developed a FRET strategy for designing...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ge An electrochemical biosensor based on methylene blue-loaded nanocomposites as signal-amplifying tags to detect pathogenic bacteria By feeds.rsc.org Published On :: Analyst, 2020, Advance ArticleDOI: 10.1039/D0AN00470G, PaperShengjun Bu, Kuiyu Wang, Zhongyi Li, Chengyu Wang, Zhuo Hao, Wensen Liu, Jiayu WanSynthesis of new methylene blue–magainin I organic–inorganic nanocomposites as electrochemical signal labels for the detection of bacteria.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ge Naked-Eye Sensing of Phytic Acid at Sub-Nanomolar Level in 100% Water Medium by Charge Transfer Complex Derived from off-the-shelf Ingredients By feeds.rsc.org Published On :: Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00671H, PaperNilanjan DeyNaked-eye sensing of phytic acid, one of the most abundant antinutrients, was achieved in 100% water medium using charge transfer complex, comprised of pyranine and methyl viologen. Since both the...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ge A homogeneous photoelectrochemical hydrogen sulfide sensor based on the electronic transfer mediated by tetrasulfophthalocyanine By feeds.rsc.org Published On :: Analyst, 2020, Advance ArticleDOI: 10.1039/D0AN00302F, PaperXinyang Wang, Huanan Zhao, Zhonghui Chen, Fang Luo, Longhua Guo, Bin Qiu, Zhenyu Lin, Jian WangA homogeneous photoelectrochemical sensor for H2S detection based on the electronic transfer mediated by [Fe(III)PcS4]+ was developed with an un-modified photoelectrode.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ge Scientific workflow managers in metabolomics: an overview By feeds.rsc.org Published On :: Analyst, 2020, Advance ArticleDOI: 10.1039/D0AN00272K, Critical ReviewAswin Verhoeven, Martin Giera, Oleg A. MayborodaMetabolomics workflows for data processing reproducibility and accelerated clinical deployment.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ge Tetrahedral DNA Nanostructure-decorated Electrochemical Platform for Simple and Ultrasensitive EGFR Genotyping of Plasma ctDNA By feeds.rsc.org Published On :: Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00591F, PaperXuyao Wang, Jianping Wu, Weilin Mao, Xia He, Liming Ruan, Junlan Zhu, Peng Shu, Zhenqi Zhang, Bitao Jiang, Xingguo ZhangGenotyping of the epidermal growth factor receptor (EGFR) mutation status is of great importance in the screening of appropriate advanced non-small cell lung carcinoma (NSCLC) patients to receive superior tyrosine...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ge A Simple and Ubiquitous Device for Picric Acid Detection in Latent Fingerprints using Carbon Dots By feeds.rsc.org Published On :: Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00750A, PaperArunkumar Kathiravan, Annasamy Gowri, Srinivasan Venkatesan, Trevor Smith, Muthpandian Ashokkumar, Asha Jhonsi MariadossThis work addresses the synthetic optimization of carbon dots (CDs) and their application in sensing picric acid from latent fingerprint by exploiting a smartphone-based RGB tool. The optimization in the...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ge [ASAP] A Coculture Based Tyrosine-Tyrosinase Electrochemical Gene Circuit for Connecting Cellular Communication with Electronic Networks By feedproxy.google.com Published On :: Thu, 02 Apr 2020 04:00:00 GMT ACS Synthetic BiologyDOI: 10.1021/acssynbio.9b00469 Full Article
ge [ASAP] Efficient and Reproducible Multigene Expression after Single-Step Transfection Using Improved BAC Transgenesis and Engineering Toolkit By feedproxy.google.com Published On :: Mon, 13 Apr 2020 04:00:00 GMT ACS Synthetic BiologyDOI: 10.1021/acssynbio.9b00457 Full Article
ge [ASAP] SCRaMbLEing of a Synthetic Yeast Chromosome with Clustered Essential Genes Reveals Synthetic Lethal Interactions By feedproxy.google.com Published On :: Fri, 17 Apr 2020 04:00:00 GMT ACS Synthetic BiologyDOI: 10.1021/acssynbio.0c00059 Full Article
ge [ASAP] Genome-Wide CRISPRi-Based Identification of Targets for Decoupling Growth from Production By feedproxy.google.com Published On :: Tue, 21 Apr 2020 04:00:00 GMT ACS Synthetic BiologyDOI: 10.1021/acssynbio.9b00143 Full Article
ge [ASAP] A Synthetic Genetic Circuit Enables Precise Quantification of Direct Repeat Deletion in Bacteria By feedproxy.google.com Published On :: Tue, 28 Apr 2020 04:00:00 GMT ACS Synthetic BiologyDOI: 10.1021/acssynbio.9b00256 Full Article
ge [ASAP] MAPPS: A Web-Based Tool for Metabolic Pathway Prediction and Network Analysis in the Postgenomic Era By feedproxy.google.com Published On :: Wed, 29 Apr 2020 04:00:00 GMT ACS Synthetic BiologyDOI: 10.1021/acssynbio.9b00397 Full Article
ge [ASAP] A Chemical Switch System to Modulate Chimeric Antigen Receptor T Cell Activity through Proteolysis-Targeting Chimaera Technology By feedproxy.google.com Published On :: Thu, 30 Apr 2020 04:00:00 GMT ACS Synthetic BiologyDOI: 10.1021/acssynbio.9b00476 Full Article
ge [ASAP] Multiplex Generation, Tracking, and Functional Screening of Substitution Mutants Using a CRISPR/Retron System By feedproxy.google.com Published On :: Mon, 04 May 2020 04:00:00 GMT ACS Synthetic BiologyDOI: 10.1021/acssynbio.0c00002 Full Article
ge [ASAP] Bacteriophage Inspired Growth-Decoupled Recombinant Protein Production in <italic toggle="yes">Escherichia coli</italic> By feedproxy.google.com Published On :: Thu, 07 May 2020 04:00:00 GMT ACS Synthetic BiologyDOI: 10.1021/acssynbio.0c00028 Full Article
ge Franz Freiherr von Eckgher, Fürstbischofs von Freising, alphabetische Sammlung zur Genealogie des bayrischen Adels, Band 4 - BSB Cgm 2268(4 By daten.digitale-sammlungen.de Published On :: Wed, 01 Apr 2020 13:12:02 +0100 Autor: Johann Franz [Freising, Bischof] Erschienen 1695 BSB-Signatur Cgm 2268(4 URN: urn:nbn:de:bvb:12-bsb00003723-2 URL: http://daten.digitale-sammlungen.de/~db/0000/bsb00003723/images/ Full Article
ge Genealogia Mändliana (der Freiherr Mändl von und zu Duntenhofen Ursprung und Aufnahme von 1613 - 1719) - BSB Cgm 2128 By daten.digitale-sammlungen.de Published On :: Thu, 16 Apr 2020 13:12:02 +0100 Autor: Erschienen 1701 BSB-Signatur Cgm 2128 URN: urn:nbn:de:bvb:12-bsb00132384-3 URL: http://daten.digitale-sammlungen.de/~db/0013/bsb00132384/images/ Full Article
ge [ASAP] Imidazo[1,2-<italic toggle="yes">a</italic>]pyridine Derivatives as Aldehyde Dehydrogenase Inhibitors: Novel Chemotypes to Target Glioblastoma Stem Cells By feedproxy.google.com Published On :: Mon, 20 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b01910 Full Article
ge [ASAP] Pyridine-Embedded Phenothiazinium Dyes as Lysosome-Targeted Photosensitizers for Highly Efficient Photodynamic Antitumor Therapy By feedproxy.google.com Published On :: Tue, 21 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00280 Full Article
ge [ASAP] Treating Cancer by Spindle Assembly Checkpoint Abrogation: Discovery of Two Clinical Candidates, BAY 1161909 and BAY 1217389, Targeting MPS1 Kinase By feedproxy.google.com Published On :: Mon, 27 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b02035 Full Article
ge [ASAP] Bioisosteric Discovery of NPA101.3, a Second-Generation RET/VEGFR2 Inhibitor Optimized for Single-Agent Polypharmacology By feedproxy.google.com Published On :: Tue, 28 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b01336 Full Article
ge [ASAP] Triazolo-Peptidomimetics: Novel Radiolabeled Minigastrin Analogs for Improved Tumor Targeting By feedproxy.google.com Published On :: Thu, 30 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b01936 Full Article
ge [ASAP] Dual-Target Inhibitors Based on HDACs: Novel Antitumor Agents for Cancer Therapy By feedproxy.google.com Published On :: Thu, 30 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00491 Full Article
ge [ASAP] Computational Chemistry on a Budget: Supporting Drug Discovery with Limited Resources<subtitle>Miniperspective</subtitle> By feedproxy.google.com Published On :: Fri, 01 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b02126 Full Article
ge [ASAP] Degradation versus Inhibition: Development of Proteolysis-Targeting Chimeras for Overcoming Statin-Induced Compensatory Upregulation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase By feedproxy.google.com Published On :: Mon, 04 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00339 Full Article
ge [ASAP] Targeting ALK2: An Open Science Approach to Developing Therapeutics for the Treatment of Diffuse Intrinsic Pontine Glioma By feedproxy.google.com Published On :: Tue, 05 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00395 Full Article
ge [ASAP] p62/SQSTM1, a Central but Unexploited Target: Advances in Its Physiological/Pathogenic Functions and Small Molecular Modulators By feedproxy.google.com Published On :: Tue, 05 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b02038 Full Article
ge [ASAP] Structural Fingerprints of an Intact Monoclonal Antibody Acquired under Formulated Storage Conditions via <sup>15</sup>N Direct Detection Nuclear Magnetic Resonance By feedproxy.google.com Published On :: Wed, 06 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00231 Full Article
ge [ASAP] Discovery of Potent Inhibitors against P-Glycoprotein-Mediated Multidrug Resistance Aided by Late-Stage Functionalization of a 2-(4-(Pyridin-2-yl)phenoxy)pyridine Analogue By feedproxy.google.com Published On :: Thu, 07 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00337 Full Article
ge [ASAP] Discovery of a Silicon-Containing Pan-Genotype Hepatitis C Virus NS5A Inhibitor By feedproxy.google.com Published On :: Thu, 07 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00082 Full Article
ge [ASAP] Ruthenium(II) Complex Containing a Redox-Active Semiquinonate Ligand as a Potential Chemotherapeutic Agent: From Synthesis to <italic toggle="yes">In Vivo</italic> Studies By feedproxy.google.com Published On :: Thu, 07 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00431 Full Article
ge [ASAP] Progress in the Field of Aldehyde Dehydrogenase Inhibitors: Novel Imidazo[1,2-<italic toggle="yes">a</italic>]pyridines against the 1A Family By feedproxy.google.com Published On :: Tue, 31 Mar 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00686 Full Article
ge [ASAP] Therapeutic Potential of Targeted Nanoparticles and Perspective on Nanotherapies By feedproxy.google.com Published On :: Thu, 02 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00075 Full Article
ge [ASAP] Design, Synthesis, and Pharmacological Evaluation of Second Generation EZH2 Inhibitors with Long Residence Time By feedproxy.google.com Published On :: Thu, 02 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00045 Full Article
ge [ASAP] Escaping from Flatland: Substituted Bridged Pyrrolidine Fragments with Inherent Three-Dimensional Character By feedproxy.google.com Published On :: Thu, 02 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00039 Full Article
ge [ASAP] Rationally Designed Covalent BCL6 Inhibitor That Targets a Tyrosine Residue in the Homodimer Interface By feedproxy.google.com Published On :: Tue, 07 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00111 Full Article
ge [ASAP] Pharmacophore-Based Virtual Screening for Identification of Negative Modulators of GLI1 as Potential Anticancer Agents By feedproxy.google.com Published On :: Wed, 08 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00639 Full Article
ge [ASAP] Novel Dithiolane-Based Ligands Combining Sigma and NMDA Receptor Interactions as Potential Neuroprotective Agents By feedproxy.google.com Published On :: Fri, 10 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00129 Full Article
ge [ASAP] Selective Covalent Targeting of Mutated EGFR(T790M) with Chlorofluoroacetamide-Pyrimidines By feedproxy.google.com Published On :: Fri, 10 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00574 Full Article
ge [ASAP] Design and Synthesis of Tetrazole- and Pyridine-Containing Itraconazole Analogs as Potent Angiogenesis Inhibitors By feedproxy.google.com Published On :: Mon, 13 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00438 Full Article
ge [ASAP] Potential Cancer Treatment by Agonists of the Stimulator of Interferon Genes By feedproxy.google.com Published On :: Mon, 13 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00117 Full Article
ge [ASAP] Complete Regression of Carcinoma via Combined C-RAF and EGFR Targeted Therapy By feedproxy.google.com Published On :: Tue, 14 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00159 Full Article
ge [ASAP] Discovery of an Atropisomeric PI3Kß Selective Inhibitor through Optimization of the Hinge Binding Motif By feedproxy.google.com Published On :: Wed, 15 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00095 Full Article
ge [ASAP] PROTAC Compounds Targeting a-Synuclein Protein for Treating Neurogenerative Disorders: Alzheimer’s and Parkinson’s Diseases By feedproxy.google.com Published On :: Tue, 28 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00192 Full Article
ge [ASAP] Development of Selective Steroid Inhibitors for the Glucose-6-phosphate Dehydrogenase from <italic toggle="yes">Trypanosoma cruzi</italic> By feedproxy.google.com Published On :: Wed, 29 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00106 Full Article